INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2024
·
IF 8.1
Yuanchen Zhu,Gang Liu,Zhenying Cui,Hongwei Yang,Fang Liu,Baolei Jiang,Lei Chen
Blending hydrogen into existing natural gas pipelines is a cost-effective method for large-scale hydrogen transportation. However, high hydrogen ratios cause hydrogen embrittlement in pipeline steel, limiting transportation efficiency. Due to complex structures and harsh application conditions, existing coatings are difficult to apply on pipelines. To tackle such issues, we propose an ionic liquid-polymer composite coating using epoxy resin as coating substrate, based on the competitive adsorption of methane and hydrogen on pipeline steel. Ionic liquids with high methane selectivity were selected via quantum chemical calculation. The protective effect of coatings was characterized using hydrogen pre-charging constant strain tensile tests. Simulation and experimental results demonstrate that epoxy resin coatings reduce hydrogen embrittlement in X80 steel. Modified with selective CH 4 /H 2 permeability ionic liquids, the epoxy resin coating enhances methane and hydrogen competitive adsorption on the steel surface, improving hydrogen embrittlement resistance. This novel coating offers a viable solution for achieving safe and high ratio hydrogen blended transportation in natural gas pipeline.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Yanan Chen,Zhonghao Jiang,Zhuo Yan,Jierong Liu,Yilin Lai,Li Li,Xiao Lin,Jiantao Lin
Sorafenib (SF) is a first-line drug for the treatment of hepatocellular carcinoma (HCC) in clinical practice. However, acquired drug resistance tremendously limits the clinical efficacy of sorafenib in treating HCC, which has attracted great attention. PDL1 plays a crucial role in the drug resistance of HCC. Here, a codelivery system based on poly-SS-lysine modified chitosan (TAT-C-SS-P) was established and was applied to deliver sorafenib and PDL1-siRNA for synergetic HCC therapy. The successful synthesis of TAT-C-SS-P was confirmed by 1 H NMR. Additionally, sorafenib and PDL1-siRNA were successfully transported into the cells as the decreased expression of VEGF and PD-L1 by administrated with TAT-C-SS-P@SF@ PDL1-siRNA. Simultaneously, the expression of pro-apoptosis proteins cyt-c and Bax was prominently augmented, whereas the expression of anti-apoptosis protein Bcl-2 was decreased. The reduced expression of PDL1 resulted in the downregulation of P-GP and MRP1, which contributed to more sorafenib aggregation in tumor cells. Moreover, TAT-C-SS-P@PDL1-siRNA@SF efficiently promotes apoptosis of HepG2-SI cells, as the apoptosis rate rised to 73 %. A sorafenib-insensitive model was established to evaluate in vivo antitumor effect of TAT-C-SS-P@PDL1-siRNA@SF. TAT-C-SS-P@PDL1-siRNA@SF showed a tumor inhibition rate of 90.2 ± 3.5 % and no significant decrease in body weight. Taken together, our study provided compelling evidence that TAT-C-SS-P@PDL1-siRNA@SF has great potential application in the treatment of HCC clinically.
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INDUSTRIAL CROPS AND PRODUCTS
·
2025
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IF 6.2
Chengshun Liu,Jianlong Li,Miao Wang,Guotai Jian,Chen Zhu,Hanxiang Li,Yongxia Jia,Jinchi Tang,Lanting Zeng
Camellia sinensis var. assamica is a major variety used to produce black tea. However, the core compounds influencing its aroma quality are unknown. In this study, Yinghong No. 9 black tea (YJBT), a distinctive black tea in South China, was analyzed. We detected 44 aroma compounds and identified seven key contributors, namely linalool, geraniol, trans -linalool oxide (furanoid), hexanal, methyl jasmonate, phenylacetaldehyde, and β-ionone. Linalool, which was generally more abundant in spring tea than in summer tea, contributed significantly to sweet and floral aromas. ( R )-Linalool was the primary linalool form in Yinghong No. 9, wherein it was highly abundant in high-quality tea leaves. The substantial expression of a linalool synthase gene and the relatively high catalytic efficiency of the encoded enzyme likely contributed to the accumulation of ( R )-linalool. This study identified the primary aroma compounds in YJBT, providing a foundation for advancing our knowledge of the aromatic quality of black tea.
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NEW JOURNAL OF CHEMISTRY
·
2024
·
IF 2.7
Yufen Wang,Yantao Wang,Yongqing Ma,Asma Mohmmad Elsharif,Chen Zhang,Weiran Yang,Christophe Len
A new transition-metal-free catalytic system which uses sodium iodide as the catalyst with formic acid as the hydrogen donor in a biphasic medium was reported for the reduction of the hydroxyl group and various unsaturated groups such as CC, CC, CN and CO. Using the same catalytic system, reductive N-formylation of nitroarenes with formic acid was explored to produce the corresponding amide in high selectivity. Moreover, the catalyst stability was evaluated and reaction mechanisms were studied and proposed for the three model reactions.
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Advanced Science
·
2025
·
IF 14.1
Kun Zhang,Ni Dan,Ruo-Yu Zhang,Jiaojiao Wei,Rui-Xue Tian,Yongfan Zhang,Hong-Ru Fu,Mei Qiu,Lu-Fang Ma,Shuang-Quan Zang
Preparing multi-color and multi-stimuli-responsive circularly polarized luminescence (CPL) materials and understanding the evolution of chirality through the visualized mode is still a challenge. Here, an encapsulation engineering approach of chiral metal-organic frameworks (MOFs) is proposed to confine guest emitters to realize multi-color and multi-stimuli-responsive CPL. Based on triplet-triplet energy transfer (TTET), white CPL and near-infrared circularly polarized room temperature phosphorescence (NIR-CPRTP) can be obtained by introducing the pyrene derivatives. With the introduction of the guest containing vinylpyrene group, the light- and thermal-responsive CPL with the signal inversion can be realized through the reversible [2+2] cycloaddition reaction between the ligand and guest triggered by visible light/ultraviolet light or heating. Furthermore, the excitation-dependent CPL is successfully achieved with the incorporation of excited state intramolecular proton transfer (ESIPT) molecules into nanopores. Importantly, the chirality magnification can be greatly enhanced through the chiral spatial confinement, the accurate host-guest single crystal structures of FLT@DCF-12 and FLT@LCF-12 provide the visualized mode to understand the mechanism of chirality transfer, amplification and responsiveness. White LED and multiple information display and encryption are further demonstrated. This breakthrough provides a new perspective to guest-encapsulated chiral MOFs and contributes to the construction of stimuli-responsive CPL-active materials.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Ding-Ming Xue,Yi-Jun Zhang,Jing-Wen Chen,Hao Yang,Rui-Jie Xie,Shi-Chao Qi,Yuan-Qing Bu,Fei Liu,Hou-Hu Zhang,Jacques Lalevée
Covalent organic frameworks (COFs), as a newly emerging kind of porous and crystalline materials, serve as an ideal template for hydrogen peroxide (H 2 O 2 ) photosynthesis. However, the vision of achieving high efficiency and selectivity in H 2 O 2 photosynthesis is greatly hindered by the large exciton binding energy and limited charge separation efficiency influenced by the molecular structure of the building blocks. Herein, we developed three newly designed COFs with a donor–acceptor (D-A) structure and incorporated regulatory units (fluorine, F, and methoxyl, OCH 3 ) in the D-A pathway through molecular engineering to optimize electronic structure, the availability of activate sites, charge kinetics and O 2 activation capacity. Due to electron-donating effect, OCH 3 -functionalization (NIES-COF-3) can strengthen the intramolecular electron transfer and interaction with O 2 . This results in a reduction of the energy barrier of the rate-determining step (*O 2 → *OOH) and excellent O 2 -to-H 2 O 2 photocatalytic activity under visible light irradiation, delivering an H 2 O 2 production rate of 3238.4 μmol g −1 h −1 and a high apparent quantum yield of 3.17 %. In addition, F-functionalization (NIES-COF-2) primarily reduces the band-gap energy and improve the O 2 adsorption capacity compared to unfunctionalized NIES-COF-1. This work unveils insight into the catalytic activity-optimization mechanism of molecular engineering in the D-A structure and provides important references for photocatalysts.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Dandan Song,Guoqiang Li,Qian Liu,Xingge Huang,Weiyu Wang,Faming Gao
The accurate monitoring of pesticide residues in agricultural products is critical for maintaining food quality and human health. The development of innovative analysis techniques capable of satisfying the stringent demands of practical applications is the key to building intelligent and highly-efficient pesticide detection equipment. Here, an ultrasensitive electrochemical biosensor has been reported, which utilizes quinary PtPdRhFeCu high-entropy alloy mesoporous nanotubes (PtPdRhFeCu HEA mNTs) and N/Cu dual-atom anchored ZnSe@C (N-Cu-ZnSe@C) as electrode materials. Multi-effect coupling (defect effect, high entropy effect, lattice distortion effect and doping effect), endows the proposed sensing interface with extremely high electronic conductive properties and unprecedentedly large electroactive surface area, which could heavily promote the charge transfer capability, meanwhile assists the acetylcholinesterase (AChE) with high affinity towards its substrate, thereby significantly improving the pesticide analysis performance of the sensor. Remarkably, the detection limit of this assembled biosensor for aldicarb sulfone and methamidophos detection are notably low at 2.32 fM and 4.58 fM, respectively. Moreover, this biosensor demonstrated wide detection ranges (7 pM ∼ 70 nM for methamidophos and 1 pM ∼ 0.1 μM for aldicarb sulfone), high sensitivity and specificity, along with good recovery rates (86.67 % ∼ 117.14 %) in real samples. This signal amplification strategy enhances the analysis capability by integrating multiple effects, and provides an innovative analysis tool for hazardous substance analysis in food safety and environmental monitoring research.
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LANGMUIR
·
2024
·
IF 3.7
Jing Wu,Shuqing Xiang,Ming Zhang,Ninglin Zhou,Mingqian Wang,Li Li,Jian Shen
Wounds caused by bacterial infections have become a major challenge in the medical field; however, the overuse of antibiotics has led to increased resistance and bioaccumulation. Therefore, it is urgent to develop an antibacterial agent with excellent antibacterial properties and biosafety. Here, we designed an antibacterial platform that combines photothermal and chemical kinetics therapies. Platinum–cobalt (PtCo) bimetallic nanoparticles (NPs) were first prepared, and then PtCo@MnO2 nanoflowers were obtained by adding MES buffer solution and KMnO4 to the PtCo bimetallic nanoparticle suspension using ultrasound. When light strikes metal NPs, they can strongly absorb the photon energy, resulting in photothermal properties. In addition, Pt and Co were used as the oxidase mimics, and MnO2 was used as the catalase mimic. In summary, the photothermal capacity of PtCo@MnO2 nanoflowers with rough surfaces can effectively disrupt the permeability of the bacterial cell membranes. Further, by catalyzing H2O2, PtCo@MnO2 nanoflowers can generate large amounts of hydroxyl free radicals, which can damage bacterial cell membranes, proteins, and DNA. In addition, MnO2 can effectively alleviate the hypoxic environment of the bacterially infected areas and activate deep bacteria, thus achieving the goal of complete sterilization. The in vitro and in vivo results showed that PtCo@MnO2 displayed excellent antibacterial properties and good biocompatibility.
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CHEMICAL ENGINEERING SCIENCE
·
2024
·
IF 4.1
Qi Liu,Tong Luo,Yiyan Yin,Yan Ouyang,Min Xiao,Hongxia Gao,Teerawat Sema,Zhiwu Liang
Amine degradation is one of the key issues that hampers the implementation of amine-based post combustion carbon capture technology. In this work, the oxidative degradation of fourteen structurally varied amines were experimentally studied by measuring the amine loss, alkalinity change, ammonia yield, and degradation product. There is a linear relationship between amine loss against alkalinity change and ammonia yield, indicating that the degradation product either loss reactivity for CO 2 absorption or emit out as the small molecule. The results have shown that amine stability generally increased with amine order and stronger steric hindrance effect. Most primary and secondary amines showed more than 40 % amine loss after 336 h degradation experiment, while most of tertiary amines showed less than 10 % amine loss. This may be due to the exposed amine groups of primary and secondary amines. The oxidative degradation mechanism was studied based on density functional theory (DFT) calculations.
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PLANT PHYSIOLOGY AND BIOCHEMISTRY
·
2024
·
IF 6.1
Siyue Liu,Jinge Xie,Wenqi Luan,Chen Liu,Xiwen Chen,Defu Chen
The current trend in agricultural development is the establishment of sustainable agricultural systems. This involves utilizing and implementing eco-friendly biofertilizers and biocontrol agents as alternatives to conventional fertilizers and pesticides. A plant growth-promoting fungal strain, that could alter root system architecture and promote the growth of Arabidopsis seedlings in a non-contact manner by releasing volatile organic compounds (VOCs) was isolated in this study. 26S rDNA sequencing revealed that the strain was a yeast-like fungus, Papiliotrema flavescens . Analysis of plant growth-promoting traits revealed that the fungus could produce indole-3-acetic acid and ammonia and fix nitrogen. Transcriptome analysis in combination with inhibitor experiments revealed that P . flavescens VOCs triggered metabolic alterations, promoted auxin accumulation and distribution in the roots, and coordinated ethylene signaling, thus inhibiting primary root elongation and inducing lateral root formation in Arabidopsis . Additionally, transcriptome analysis and fungal infection experiments confirmed that pretreatment with P . flavescens stimulated the defense response of Arabidopsis to boost its resistance to the pathogenic fungus Botrytis cinerea . Solid-phase microextraction, which was followed by gas chromatography-mass spectrometry analysis, identified three VOCs (acetoin, naphthalene and indole) with significant plant growth-promoting attributes. Their roles were confirmed using further pharmacological experiments and upregulated expression of auxin- and ethylene-related genes. Our study serves as an essential reference for utilizing P . flavescens as a potential biological fertilizer and biocontrol agent.
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NEW JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 24
·10820-10829
·
IF 2.7
Weichuan Xu,Hong Huang,Lingling Bi,Haimei Xu,Zhichao Miao,Mei Wu
Carbonyl compounds serve as essential raw materials in the production of fine chemicals and pharmaceuticals. An economical and environmentally-friendly route to generating carbonyl compounds involves the catalytic oxidation of alcohols and hydrocarbons using heterogeneous catalysts. In this work, we synthesize a series of vanadium-doped ordered mesoporous zirconium oxophosphate (V/M-ZrPO) nanocomposites via a modified one-pot evaporation-induced self-assembly approach. Characterization results confirm the successful embedding of vanadium species into the framework of the M-ZrPO support. Dispersion of vanadium sites generates catalysts exhibiting enhanced performance for the selective oxidation of alcohols and hydrocarbons to carbonyl compounds. In particular, the 20 V/M-ZrPO catalyst demonstrates excellent reusability and broad substrate compatibility. Relative to established catalytic materials, the 20 V/M-ZrPO catalyst demonstrated superior performance across key metrics including product yield, reaction time, and recyclability. These findings highlight the promise of V/M-ZrPO nanocomposites as efficient and durable catalysts for sustainable carbonyl compound production.
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LANGMUIR
·
2024
·
IF 3.7
Zeqi Wu,Feng Niu,Wenhao Yao,Siyuan Gao,Da Chen,Yuexiang Huang
The activation of an inert C(sp3)–H bond in selective oxidation of hydrocarbons under mild conditions is a critical and challenging process. Herein, we report a stable chlorine-coordinated metal–organic framework (MOF) photocatalyst, MIL-101(Fe), for efficient visible-light-driven photocatalytic selective oxidation of toluene to benzaldehyde in air under ambient conditions. Encouragingly, a benzaldehyde formation yield of 3.11 mmol·g–1·h–1 with a selectivity of 92.1% is achieved in 5 h, which is superior to most of the reported works. Based on the experimental results and characterizations, the high catalytic performance is mainly due to the promoted rate-limiting step of C(sp3)–H bond activation by a chlorine radical (Cl·) from the coordinated −Cl in the MIL-101(Fe) structure. In addition, the present photocatalyst possesses good substrate tolerance for photocatalytic selective oxidation of various toluene derivatives under optimized conditions.
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