DYES AND PIGMENTS
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2020
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IF 4.613
Wen Li,Ziyu Huo,Xiaomeng Zhang,Haitao Zhao,Zhe Cui,Peng Fu,Minying Liu,Xiaoguang Qiao,Weihua Fan,Xinchang Pang
A silane based AIE probe (APTS-TPE) was prepared through the incorporation of (3-Aminopropyl)triethoxysilane (APTS) and tetraphenylethylene (TPE), and applied for in-situ visual monitoring of the silica growth in Stöber process. The TPE groups in the APTS-TPE structure can be anchored in the -Si-O-Si- molecular network and exhibited strong fluorescence emission owing to the restriction of intramolecular motion of TPE group. Real-time in-situ particles size analysis and photoluminescence (PL) intensity analysis were carried out to follow the evolution of PL intensity with particle size. The relationship between silica size and PL intensity in parallel experiments were also discussed. Compared with traditional characterization methods, this method has the potential application for silica industrial production and fundamental research, with the advantage of sensitive, rapid and non-invasive.
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高影响因子
Journal of Materials Chemistry C
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2020
·Vol. 8
·期 30
·10408-10415
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IF 7.059
Siqi Xie,Qi Liu,Fawei Zhu,Miao Chen,Lumin Wang,Yu Xiong,Yuqiu Zhu,Yu Zheng,Xiaoqing Chen
By binding aggregation-induced emission luminogens (AIEgens) with nanoscale ZIF-8, a series of novel luminescent metal–organic frameworks (LMOFs) with good photostability and excellent dispersibility have been facilely fabricated. The developed AIE-active MOFs not only inherit the intriguing AIE properties of AIEgens, including excited-state intramolecular proton transfer (ESIPT) properties, intense solid-state luminescence and large Stokes shifts (115–202 nm), but also show surprisingly boosted fluorescent emission efficiency (over 16 times) when compared with the original fluorescence of AIEgens. Meanwhile, the emission of AIE-active MOFs could also be finely engineered by varying the substituents on AIEgens. And as a proof of concept, the selected AIE-active MOF-2 (LMOF-2) served as a novel fluorescent probe for detecting copper ions (Cu2+), and a considerable response range (1–100 nM) and a sensitive picomolar detection limit (550 pM) were favorably obtained. More importantly, based on a glucose oxidase (GOD) catalyzed cascade redox reaction of LMOF-2/GOD nanocomposites, a fluorescent allochroic test strip was favourably developed for visual detection of glucose within a normal concentration range of fasting blood-glucose in human sera (3–8 mM), and has great potential to be applied in on-site assay of glucose in real serum samples due to its praiseworthy specificity and selectivity.
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高影响因子
Materials Chemistry Frontiers
·
2019
·Vol. 3
·期 6
·1052-1061
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IF 0
Tingting Lin,Xing Su,Kai Wang,Minjie Li,Hongwei Guo,Lulu Liu,Bo Zou,Yu-Mo Zhang,Yifei Liu,Sean Xiao-An Zhang
Stimuli-responsive fluorescent materials which can change their optical signal outputs upon changes in ambient physical or chemical parameters exhibit great application potential for comprehensive environmental monitoring. In this article, a new aggregation-induced emission fluorescent switch, 1',3′,3′-trimethyl-5′-(4-(1,2,2-triphenylvinyl)phenyl)spiro[chromene-2,2′-indoline]-6-carbonitrile (TPE-Sp-CN), was synthesized and applied in the quantitative detection of three parameters, namely pH value, sulfite anion and hydrostatic pressure, with different molecular states. According to the analysis of the optical spectra, TPE-Sp-CN can distinguish water pH values from 0 to 4, the detection limit of sulfite anion is 1.04 ppm, and the pressure sensing range is 1 atm to 6 GPa with the sensing sensitivity of a 9.876 nm GPa−1 shift in the PL spectrum. Furthermore, TPE-Sp-CN can quantitatively sense all three parameters with good linear relationships, which is rarely reported. Also, it is promising to use TPE-Sp-CN as an indicator to monitor the environment or disasters that are related to the above parameters, such as harmful geological activities.
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DYES AND PIGMENTS
·
2019
·
IF 4.018
Linfeng Chen,Xike Tian,Yong Li,Chao Yang,Liqiang Lu,Zhaoxin Zhou,Yulun Nie
Portable, rapid, accurate and on-site detection of analysis target has always been the goal of continuous efforts in the field of analysis. In this work, a novel intelligent and rapid detection system based on an AIE dye (TPA-DCV) was established for portable and on-site detection of trace water in organic solvents and CN − in water by integrating the smartphone and linear discriminant analysis (LDA). The TPA-DCV displayed remarkable solvatochromism effect and showed different fluorescence colors to different water contents of different solvents, with the minimum detection limit of 54 ppm. In addition, TPA-DCV also exhibited specific response to CN − , and showed significant fluorescence changes to different amounts of CN − . With the assist of this detection system, these different fluorescence color signals could be accurately classified in canonical score plot. What's more, the classification and distribution of fluorescence color in canonical score plot showed regular change with the target concentration, which could be used to quantify the trace water and CN − . The rationality and practicability of this detection system were preliminary verified by a large number of real sample analyses. This detection system greatly simplifies the analysis process, which is in the proof of intelligent and rapid detection just using a simple color analysis without any instrument test, which may be a big step forward.
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高影响因子
DYES AND PIGMENTS
·
2018
·
IF 3.767
Yanzhu Liu,Liucheng Mao,Saijiao Yang,Meiying Liu,Hongye Huang,Yuanqing Wen,Fengjie Deng,Yongxiu Li,Xiaoyong Zhang,Yen Wei
In recent years, florescent polymeric nanoparticles (FPNs) containing aggregation-induced emission (AIE) fluorogens have received great intention for their potential applications in biological imaging and theranostic nanomedicine . Herein, we have developed AIE-active FPNs through a combination of reversible addition-fragmentation chain transfer (RAFT) polymerization and post-polymerization modification strategies. The salicylaldehyde (SA) containing zwitterionic copolymers are fabricated via RAFT polymerization and further modified by benzophenone hydrazone (BPH) via Schiff base reaction. The obtained AIE-active amphiphilic copolymers BPH-poly(FHMA- co -MPC) can self-assemble in aqueous solution with the hydrophobic fluorogens aggregating together to form the core and the hydrophilic chains to form the protective shell. BPH-poly(FHMA- co -MPC) and the resulting FPNs are characterized by 1 H nuclear magnetic resonance spectroscopy , Fourier transform infrared spectroscopy, transmission electron microscopy and fluorescence spectroscopy . Results demonstrate that BPH-poly(FHMA- co -MPC) are successfully synthesized and as-prepared BPH-poly(FHMA- co -MPC) FPNs exhibit desirable morphology and size, good dispersibility , high brightness, remarkable photostability and large Stokes shifts . More importantly, through cytotoxicity test and cell uptake behavior, these BPH-poly(FHMA- co -MPC) FPNs show low toxicity and excellent cell dyeing behavior. Taken together, we have developed a facile and effective method for the fabrication of AIE-active FPNs, which display great potential for biomedical applications .
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高影响因子
APPLIED SURFACE SCIENCE
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2017
·
IF 3.387
Liucheng Mao,Xinhua Liu,Meiying Liu,Long Huang,Dazhuang Xu,Ruming Jiang,Qiang Huang,Yuanqing Wen,Xiaoyong Zhang,Yen Wei
Aggregation-induced emission (AIE) dyes have recently been intensively explored for biological imaging applications owing to their outstanding optical feature as compared with conventional organic dyes. The AIE-active luminescent silica nanoparticles (LSNPs) are expected to combine the advantages both of silica nanoparticles and AIE-active dyes. Although the AIE-active LSNPs have been prepared previously, surface modification of these AIE-active LSNPs with functional polymers has not been reported thus far. In this work, we reported a rather facile and general strategy for preparation of polymers functionalized AIE-active LSNPs through the surface-initiated atom transfer radical polymerization (ATRP). The AIE-active LSNPs were fabricated via direct encapsulation of AIE-active dye into silica nanoparticles through a non-covalent modified Stöber method. The ATRP initiator was subsequently immobilized onto these AIE-active LSNPs through amidation reaction between 3-aminopropyl-triethoxy-silane and 2-bromoisobutyryl bromide. Finally, the zwitterionic 2-(methacryloyloxy)ethyl phosphorylcholine (MPC) was selected as model monomer and grafted onto MSNs through ATRP. The characterization results suggested that LSNPs can be successfully modified with poly(MPC) through surface-initiated ATRP. The biological evaluation results demonstrated that the final SNPs-AIE-pMPC composites possess low cytotoxicity, desirable optical properties and great potential for biological imaging. Taken together, we demonstrated that AIE-active LSNPs can be fabricated and surface modified with functional polymers to endow novel functions and better performance for biomedical applications. More importantly, this strategy developed in this work could also be extended for fabrication of many other LSNPs polymer composites owing to the good monomer adoptability of ATRP.
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高影响因子
Journal of Materials Chemistry B
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2016
·Vol. 4
·期 34
·5692-5699
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IF 4.872
Qing Wan,Guangjian Zeng,Ziyang He,Liucheng Mao,Meiying Liu,Hongye Huang,Fengjie Deng,Xiaoyong Zhang,Yen Wei
Aggregation-induced emission (AIE) dyes based on fluorescent organic nanoparticles (FONs) have attracted increasing interest over the past few years. However, the biomedical applications of AIE dyes based on FONs for simultaneous biological imaging and therapeutic applications have rarely been reported thus far. In this study, an amino group terminated phenothiazine (named as ATPHE) with AIE features and red fluorescence was synthesized and utilized for the fabrication of AIE active FONs via a facile one-pot strategy, which relied on the ring-opening reaction between ATPHE and an anhydride containing compound. Then, the keto group of the AIE active polymeric intermediate was subsequently conjugated with hydrazide terminated polyethylene glycol (HTPEG) through the formation of hydrazone bonds. These amphiphilic AIE active copolymers are readily self-assembled into nanoscale particles in an aqueous solution, which resulted in strong luminescence and good water dispersibility of the final HTPEG@ATPHE-co-BTDA FONs. The excellent physicochemical and biological properties of HTPEG@ATPHE-co-BTDA FONs give them high potential for biological imaging and controlled drug delivery applications. Taken together, we developed a simple strategy for the fabrication of AIE active nanoparticles, which are promising for biological imaging and controlled drug delivery.
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PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Shuang Liu,Chenxi Zhao,Huiya Yuan,Lina Gao,Yan Zhang
Rapid and accurate field testing for oxytetracycline (OTC) is crucial for ensuring food safety and monitoring environmental pollution. Herein, we report the construction of an aggregation-induced emission metal-organic frameworks (MOFs)-mediated molecularly imprinted ratio metric fluorescent sensor (AIE/Eu@MIPs) for the rapid and selective detection of OTC with high sensitivity. AIE MOFs with ultra-high quantum yield were utilized as the blue fluorescence emission carriers, thus avoiding any compromise between convenience and cost-effectiveness. The detection sensitivity was significantly enhanced by modifying the fluorescence signals, driven by the combined effects of the inner filter effect (IFE) and antenna effect (AE). The detection limit was as low as 21 nM (about 9.67 μg/kg). More importantly, a portable optical sensing platform integrating AIE/Eu@MIPs was developed for visual detection of OTC. The developed probe and portable device-based sensing platform demonstrate considerable potential for on-site detection of OTC in real-world applications.
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PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
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2024
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IF 10.7
Yunyun Hu,Xi Chen,Kai Wang,Chuang Jiang,Wenya Liu,Siyu Zhang,Mingming Zheng,Yibin Zhou,Yaqing Xiao,Yingnan Liu
In this study, based on aggregation-induced emission (AIE) effect and antenna effect, a novel portable fluorescent responsive membrane was constructed with red carbon dots (R-CDs) as reference signal and terbium coordination polymer (Tb-AMP CPs) as response signal for visual, instrument-free, and sensitive detection of fluoroquinolones (FQs). Specifically, the fluorescent responsive membrane (R-T membrane) was prepared by physically depositing R-CDs with AIE property and Tb-AMP CPs on the surface of polyvinylidene fluoride filter membranes at ambient temperature. In the presence of FQs, Tb 3+ in the Tb-AMP CPs of the prepared membrane coordinated with the β-diketone structure of FQs, which turned on the yellow-green fluorescence through the “antenna effect”. As the concentration of FQs increased, the R-T membrane achieved a fluorescent color transition from bright pink to yellow-green. Its visual detection sensitivity for three FQs, including ciprofloxacin, difloxacin, and enrofloxacin, was 0.01 μM, and the detection limits were 7.4 nM, 7.8 nM, and 9.2 nM, respectively, by analyzing the color parameter green. In the residue analysis of FQs in real samples, the constructed membrane also exhibited remarkable anti-interference and reliability, which is of great significance for ensuring the safety of animal-derived food.
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PubMed
高影响因子
MICROCHEMICAL JOURNAL
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2025
·
IF 5.1
Xinran Yang,Yuanyuan Liu,Yang Li,Ruixue Sun,Yiming Zhang,Donghui Wang
Rapid and accurate detection of trace cadmium ions (Cd 2+ ) in the environment and foodstuff is great of significance. Herein, we developed a fluorescent paper-based analytical platform for Cd 2+ detection with dual recognition modes based on the paper-based ion imprinting chip (Cd-IIP) and an aggregation-induced emission (AIE) probe (PBQ) for the first time. Cd-IIP was prepared based on sol–gel technique using 3-mercaptopropyltriethoxysilane (MPTES) as the functional monomer, Cd 2+ as the ionic template, and tetraethyl silicate (TEOS) as the cross-linking agent. Cd-IIP could selectively enrich Cd 2+ with good adsorption capacity (385.00 mg g −1 ) and imprinting factor (IF = 5.3). Benefiting from the PBQ with specific recognition of Cd 2+ based on metal coordination-induced AIE effect, the platform exhibited superior selectivity and recognition efficiency to Cd 2+ . The platform showed a wide linear range from 0.01 to 10 μg mL −1 with the limit of detection (LOD) as low as 0.0045 μg mL −1 under the synergy of the biomimetic recognition and AIE effect. Moreover, the smartphone-based analytical method was utilized for visual detection of Cd 2+ with the LOD of 0.11 μg mL −1 in real samples. Overall, this analytical platform possessed significant specificity and sensitivity, holding a great promise of dual selective principles for efficient analysis of Cd 2+ in complex systems.
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高影响因子
DYES AND PIGMENTS
·
2017
·
IF 3.473
Mingguang Zhu,Youzhen Zhuo,Kaicong Cai,Hongyu Guo,Fafu Yang
A novel perylene liquid crystal with diphenylacrylonitrile groups on 1,7-bay positions was synthesized in high yield. This highly decorated perylene bisimide showed the ordered hexagonal columnar liquid crystalline behaviour between 124.9 and 189.5 °C. Upon excitation of 480 nm, an attenuation of fluorescent intensity was observed with the increase of water fraction in THF/H 2 O mixtures. However, the fluorescence intensity enhanced dramatically and attained a maximum value at water fraction of 40% in THF/H 2 O systems when excited at 330 nm. The fluorescence intensity increased by 10 times and the pseudo Stokes shift achieved 251 nm. These phenomena were well elucidated by the AIE and FRET effect, which were supported by the investigation of fluorescence quantum yield and fluorescence lifetime .
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高影响因子
Journal of Materials Chemistry C
·
2025
·
IF 5.1
Weiwei Zhang,Yongbo Wei,Fen Lin,Yinyin Yao,Xia Wang,Yongxiao Sun,Jingming Zhou,Tong Wu,Nannan Chen,Yusheng Lu,Xiaoping Wu,Lijun Xie
In this work, a new series of rofecoxib analogues were designed and synthesized by employing the migration of the donor (D) group and donor (D)–acceptor (A) switching principle to achieve ACQ–AIE conversion. Among them, when the D unit dimethylamino was anchored on the para-position of the benzene ring D, the corresponding compound L1, namely (Z)-5-(4-(dimethylamino)benzylidene)-4-(4-(methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one, was obtained exhibiting obvious aggregation-caused quenching (ACQ) behavior. Subsequently, after migrating the D group from ring D to ring B, the resulting L2 exhibits an aggregation-induced emission (AIE) effect. Meanwhile, by switching the position of the D and A units based on the structure of L1, the corresponding compound L3 also shows AIE behavior. These results demonstrate that migrating the position of the donor group and switching the positions of the donor and acceptor have significant effects on the fluorescent properties of the compounds. Moreover, single crystal X-ray analysis of L2 and L3 revealed that the stronger molecular C–H⋯π interactions contribute to greater structural rigidification, which in turn enhances their bright emission in the solid state. In addition, L2 and L3 exhibited solvatochromic, acidichromic, and trace water properties with reversible multi-stimulus behaviors. More importantly, L2 and L3 demonstrated highly specific fluorescent imaging ability (RL2 = 0.97, RL3 = 0.98) toward lipid droplets in living MCF-7 cells, with low cytotoxicity. In summary, the creative design concepts of adjusting the position of D and switching the positions of D and A units, as well as the ACQ to AIE conversion provide alternative ways for developing new multifunctional AIEgens, L2 and L3.
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高影响因子
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