Food Chemistry-X
·
2024
·
IF 6.5
Xingyu Zhu,Chong Chen,Dou Che,Hui Yan
To improve the activity of single-atom nanozymes (SAzymes) for applications in food analysis, a new bimetal SAzyme FeCe/NC was developed. Its oxidase-like activity is 40% higher than that of single metal SAzyme Fe/NC. Based on a series of characterization investigations, the catalytic mechanism is that it directly catalyzed O 2 to generate • OH, O 2 • - and 1 O 2 . It could directly catalyze oxidation 3,3′,5,5′-tetramethylbenzidine (TMB) to blue oxTMB, thereunder, a FeCe/NC SAzyme-TMB colorimetric method for the detection of tannic acid (TA) was constructed after the optimization of catalytic conditions. The method has a high R 2 of 0.995, a low limit of detection (LOD) of 0.26 μmol/L, and high stability. The detection performance was validated by the real samples (tea). Therefore, the prepared bimetallic SAzyme FeCe/NC can be applied for TA detection without the addition of H 2 O 2 , and will have broad applications in the areas of food, feed, and life science.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Yixing Luo,Qingsheng Wu,Yongqing Fu,Ming Wen
Built-in electric field (BIEF) in metallic chalcogenide heterostructures has recently attracted significant attention due to its special interfacial electronic structure and appropriate reaction microenvironment for improving electrocatalytic performance. However, constituent dissolution issues and inferior stability of transition metal selenide heterostructure severely inhibit the formed BIEF to support long-term high-activities for ORR and OER toward zinc-air battery (ZAB). Herein, BIEF was established in CoSe 2 -FeSe 2 hetero-nanostructures encapsulated by N-doped carbon shell on N-doped honeycomb carbon (CoSe 2 -FeSe 2 @NC/NHC) for achieving long-term efficient oxygen electrocatalysis. DFT calculation results confirm that the durable BIEF formed in CoSe 2 -FeSe 2 @NC on NHC not only optimizes interfacial electronic structures and surface adsorption energy, but also offers numerous hyperactive interfacial sites during electrocatalytic reactions. Consequently, the designed CoSe 2 -FeSe 2 @NC/NHC exhibits remarkable performance for both ORR ( E 1/2 = 0.87 V) and OER ( E j = 10 mA cm-2 = 1.54 V), enabling superior peak power density and long-term charging-discharging stability in both liquid-state ZAB (184.3 mW cm −2 and 1350 cycles) and flexible all-solid-state ZAB (61.4 mW cm −2 and 195 cycles). The high durability of BIEF in the core–shell hetero-nanostructured electrocatalyst is crucial for long-term highly-active oxygen electrocatalysis in ZAB.
研究领域:
材料科学
·
电化学
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JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2022
·
IF 6.364
Huabei Qi,Ding Zhou,Xiaohui Li,Wei Jing,Weiwei Li,Jiayue Xu
Nanocrystalline powders and pressureless sintering (NC-PLSH) were used in a H 2 atmosphere to fabricate 4 at.% La 3+ doped (Tb x Lu 0.96−x ) 2 O 3 magneto-optical transparent ceramics. La 3+ was utilised as a sintering aid, and Lu 3+ was used as a phase stabiliser . A component of the (Tb x Lu 0.96−x La 0.04 ) 2 O 3 magneto-optical material was designed and investigated based on powder sinterability and green compact sintering. Transparent (Tb x Lu 0.96−x La 0.04 ) 2 O 3 ceramics were obtained by using a one-step sintering process in H 2 atmosphere, without the need for subsequent hot isostatic pressing . The in-line transmittance of the as-polished 4 at.% La 3+ :(Tb 0.8 Lu 0.16 ) 2 O 3 ceramic was 79% at 1400 nm. The measured Verdet constant at wavelengths of 633 nm and 1064 nm was 354 rad/(T·m) and 100.2 rad/(T·m), respectively. The required length of the (Tb 0.8 Lu 0.16 La 0.04 ) 2 O 3 ceramics was 63% less than that of Tb 3 Ga 5 O 12 ceramics.
研究领域:
材料科学
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陶瓷学
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光学材料
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磁光学
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固体物理
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EUROPEAN JOURNAL OF PHARMACOLOGY
·
2022
·
IF 5.195
Hongyu Zhou,Yang Zhang,Yuan Tian,Yushi Sun,Yajuan Chen,Yanli Zhang,Qin Zhu,Junfang Pan,Chen Qing
9-nitrocamptothecin (9-NC), an active derivative of camptothecin (CPT), demonstrated antitumor effect on experimental tumors in mice by topoisomerase I (Topo I) inhibition. However, under human physiological conditions, the rapid opening of lactone ring of 9-NC resulting in the formation of inactive and high toxic carboxylate limited its clinical efficacy. Therefore, strategies aimed to maintain the active closed-lactone form of 9-NC in the plasma were developed, such as prodrugs . In our study, 9-nitro-20(S)-carbonate-camptothecin (NCP4), a novel prodrug of 9-NC, was designed and synthesized. A preclinical evaluation of the chemotherapeutic potential of NCP4 was performed in vitro and in vivo . In cytotoxicity assay against six human cancer cells, the cytotoxic effect of NCP4 was slightly weaker than 9-NC. In addition, our data showed that 9-NC can be converted from NCP4 in vivo , and that the intracellular conversion of NCP4 to its active metabolites was correlated well with its cytotoxicity, demonstrating that NCP4 could serve as a prodrug of 9-NC. In human hepatoma Bel-7402 xenografts, NCP4 by intravenous injection showed more potent antitumor efficacy than 9-NC. Mechanistically, NCP4 induced cell apoptosis by increasing the expressions of caspase-3 and Bax in tumor tissues. In human hepatoma Hep G2 xenografts, NCP4 by oral administration significantly inhibited tumor growth. Importantly, the toxic effect of NCP4 on mice was much lower than 9-NC, demonstrating improved safety of NCP4. Overall, our study indicated that NCP4 would be a promising anticancer candidate and worthy of further investigation.
研究领域:
肿瘤学
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药理学
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分子生物学
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Polymers
·
2023
·Vol. 15
·期 3
·734
·
IF 5
Jinliang Ma,Longlong Liu,Zihao Chen,Minghui Wang,Han Wu,Hongmiao Wang,Ding Yuan,Xin Ning
Exploring high-efficiency, low-cost, and long-life bifunctional self-supporting electrocatalysts is of great significance for the practical application of advanced rechargeable Zn-air batteries (ZABs), especially flexible solid-state ZABs. Herein, ultrathin CoFe-layered double hydroxide (CoFe-LDH) nanosheets are strongly coupled on the surface of leaf-like bimetallic metal-organic frameworks (MOFs)-derived hybrid carbon (Co@NC) nanoflake nanoarrays supported by carbon cloth (CC) via a facile and scalable method for rechargeable and flexible ZABs. This interfacial engineering for CoFe-LDHs on Co@NC improves the electronic conductivity of CoFe-LDH nanosheets as well as achieves the balance of oxygen evolution reduction (OER) and oxygen reduction reaction (ORR) activity. The unique three-dimensional (3D) open interconnected hierarchical structure facilitates the transport of substances during the electrochemical process while ensuring adequate exposure of OER/ORR active centers. When applied as an additive-free air cathode in rechargeable liquid ZABs, CC/Co@NC/CoFe-LDH-700 demonstrates high open-circuit potential of 1.47 V, maximum power density of 129.3 mW cm−2, and satisfactory specific capacity of 710.7 mAh g−1Zn. Further, the flexible all-solid-state ZAB assembled by CC/Co@NC/CoFe-LDH-700 displays gratifying mechanical flexibility and stable cycling performance over 40 h. More significantly, the series-connected flexible ZAB is further verified as a chain power supply for LED strips and performs well throughout the bending process, showing great application prospects in portable and wearable electronics. This work sheds new light on the design of high-performance self-supporting non-precious metal bifunctional electrocatalysts for OER/ORR and air cathodes for rechargeable ZABs.Keywords:carbon fiber;bifunctional electrocatalysts;bimetallic MOFs;self-supporting electrodes;Zn-air battery
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APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Yuxiang Mao,Jun Cheng,Hao Guo,Lei Qian,Jiacan Tu,Weijuan Yang
To enhance catalytic acid-base sites in ZIFs and efficiently promote conversion of microalgal lipids, a bifunctional catalyst with single-atom Fe-N 4 sites and Fe nanoparticles (NPs) was synthesized by pyrolyzing Fe-doped ZIF-8. Compared with ZIF precursors, Fe nanoparticles and coordinated Fe ions in Fe-N 4 sites enhanced Lewis acidity, while increased uncoordinated N atoms enhanced Lewis basicity. Therefore, the acidity of Fe-NC increased from 0.473 to 1.845 mmol/g, while basicity increased from 0.172 to 0.439 mmol/g. DFT calculations showed that the adsorption energies of acetic acid on the Fe–N 4 and Fe NP were −0.536 eV and −0.397 eV, respectively, exceeding that (-0.190 eV) on the Zn–N 4 site. The energy barriers for rate-determining steps over the Fe-N 4 and Fe NP were + 0.32 eV and + 0.21 eV, respectively, which were lower than that (+1.01 eV) over the Zn-N 4 site. The maximum biodiesel yield reached 98.3% over Fe-NC catalyst, higher than that (84.5%) over ZIF-8 catalyst.
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ELECTROCHIMICA ACTA
·
2023
·
IF 6.6
Jiongfan Wang,Lingling Chen,Xin Chen,Xinyu Li,Jianrong Xiao
Lithium-sulfur (Li-S) batteries receive considerable attention for their high energy density, but their slow reaction kinetics and poor shuttle effects raise concerns. Here, synthesized V 2 O 3 spheres were used as substrate templates, and ZIF-67 particles were grown on the surface of V 2 O 3 by in-situ growth method. ZIF-67 was calcined at high temperature to form N-doped porous carbon attached to the surface of V 2 O 3 spheres (Co-NC@V 2 O 3 -sp). The hollow structure of V 2 O 3 spheres provided abundant buffer space for sulfur volume expansion and enhanced the stability of the battery cycle. In addition, the great pore volume and specific surface area resulted in abundant active physical and chemical sites, the strong chemical adsorption of V 4+ effectively trapped polysulfides , and the cobalt nanoparticles on the surface effectively consolidated the active sites. The rapid transformation between shuttle effect and polysulfides were limited by physical coordination and chemisorption, respectively. Owing to this double synergistic effect, the prepared composites had an initial discharge capacity of 1483 mAh g −1 (0.1 C). The initial specific capacity reached 1002 mAh g −1 (0.5 C), and it achieved 645 mAh g −1 after 500 cycles. These results showed that Co-NC@V 2 O 3 -sp has high electrochemical function in Li-S batteries.
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POLYHEDRON
·
2024
·
IF 2.4
Yuxiu Gong,Bei Zhao,Ning Wang,Shuaihua Jiang,Haibin Yu,Peng Liang,Tiantian Jiao,Bu Xu,Xing Fan,Guoming Zhao
The catalytic hydrogenation of aromatic nitro compounds under mild conditions to generate amino compounds is a great challenge in terms of conversion, selectivity and stability. In this paper, two classes of nitrogen-doped carbon coated nickel nanoparticles, coined Ni@NC-P and displaced Ni@NC-T were prepared by high-temperature pyrolysis of MOFs using inexpensive terephthalic acid and high-priced trimesic acid as carbon source, respectively. One from the former class, namely the Ni@NC-P-500 catalyst, exhibits the best catalytic performance, which is superior to Ni@NC-T-500 Samples. For the selective hydrogenation of p -nitrophenol under mild conditions (60 °C, 2 h), the Ni@NC-P-500 catalyst shows >99.9 % conversion of p -nitrophenol and >99.9 % selectivity for p -aminophenol and can be recycled five times without obvious decrease of conversion and selectivity, thanks to its larger specific surface area (382.02 m 2 ·g −1 ), smaller nickel particle size (8.2 nm), higher nitrogen content (especially pyridine nitrogen), higher electron-rich nickel content and less hydrophilic properties than that of the Ni@NC-T-500. The excellent stability and recyclability of the catalysts are mainly attributed to their core–shell structure, i.e., zero-valent nickel nanoparticles encapsulated within a nitrogen-doped carbon layer with an appropriate microporous structure, whereas zero-valent nickel nanoparticles have the ability to activate dihydrogen and block dioxygen.
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Materials Today Physics
·
2026
·
IF 9.3
Wenjing Zhang,Yong Yuan,Xiaolong Li,Zhixin Liao,Xiaohua Zhang,Cuicui Du,Jinhua Chen
While alkaline water electrolysis represents a highly promising and sustainable pathway for hydrogen production, its widespread application is hindered by the sluggish kinetics of the hydrogen evolution reaction (HER) due to a large energy barrier for water dissociation. In this work, a heterogeneous electrocatalyst of Ru/MoC-Mo 2 C@NC was prepared by uniformly embedding ruthenium nanoparticles within a nitrogen-doped carbon matrix hosting MoC-Mo 2 C heterojunctions. (MoC-Mo 2 C@NC). Electrochemical experimental results demonstrate the remarkably boosted HER catalytic performance of Ru/MoC-Mo 2 C@NC compared with Ru/NC, Ru/MoC@NC and Ru/Mo 2 C@NC by presenting the lowest overpotential of 18.5 mV at 10 mA cm −2 and Tafel slope of 61.71 mV·dec −1 , along with superior intrinsic activity and mass specific activity. Density-functional theory calculations further reveal that the enhanced electronic metal-support interaction (EMSI) between Ru sites and the MoC-Mo 2 C@NC support in Ru/MoC-Mo 2 C@NC induces significant charge redistribution and interface charge accumulation in Ru/MoC-Mo 2 C@NC, thereby optimizing water dissociation energy barrier and hydrogen adsorption free energy (ΔG H∗ ). Meanwhile, this reinforced EMSI facilitates efficient reverse hydrogen spillover at the Ru/MoC-Mo 2 C@NC interface, which further favors water dissociation on Mo sites and hydrogen desorption on Ru sites of Ru/MoC-Mo 2 C@NC. These regulating effects collectively accelerate the hydrogen intermediate transport and enhance the overall HER kinetics. This work provides valuable insights into enhanced electronic metal-support interaction on a heterostructure catalytic system optimizing both water dissociation and reverse hydrogen spillover for designing highly efficient water electrolysis catalysts.
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Nutrients
·
2025
·Vol. 17
·期 20
·3249
·
IF 5
Ting Xia,Zhenjie Liu,Wenya Ding,Liting Deng,Xinyang Ning,Jianfang Feng
Background/Objectives:Achyranthes bidentata(AB), recognized as a food and traditional Chinese medicine, exhibits notable biological activity. Our previous study showed the hypoglycemic effect ofAchyrantha bidentata polysaccharide(ABP). The properties and digestion process of polysaccharides affect their pharmacological activities. The digestion characteristics of ABP are unclear. In this study, we aimed to explore the characteristics of ABP’s simulated digestion and its prebiotic properties and hypoglycemic effects.Methods: We used simulated digestion methods to investigate the alterations in ABP levels in the process of digestion and fermentation. Animal experiments were used to compare the effects of the prebiotic properties of ABP on normal control (NC) and type 2 diabetes mellitus (T2DM) mice. Then, in order to further verify the hypoglycemic effect of ABP after fermentation (ABPF), α-glucosidase activity and glucose uptake in Caco-2 cells were examined.Results: The results showed that ABP was anti-digestive and mainly degraded by the intestinal flora. Moreover, ABP showed a stronger promoting advantage against beneficial bacteria and inhibited harmful bacteria in the T2DM mice. Compared with NC mice, after ABP treatment, T2DM mice showed a higher increase in levels of short-chain fatty acids (SCFAs). Additionally, the glucose uptake and α-glucosidase activity of Caco-2 cells were significantly decreased after treatment with ABPF.Conclusions: These results underscore the potential of ABP as a prebiotic candidate for gut health promotion and T2DM alleviation.
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高影响因子
ELECTROCHIMICA ACTA
·
2019
·
IF 5.383
Rui Fang,Wei Xiao,Chang Miao,Ping Mei,Yan Zhang,Xuemin Yan,Yu Jiang
The core-shell structural N-doped carbon encapsulating Si@TiO 2 composite (Si@TiO 2 /NC) are prepared by facile sol-gel, polymerization of dopamine hydrochloride and the following heat treatment processes, which are confirmed by the scanning electron microscopy, X-ray diffractometer, transmission electron microscopy , X-ray photoelectron spectroscopy and thermogravimetric analyses. The as-prepared Si@TiO 2 /NC composite present favorable spherical shape with about 150 nm in diameter and uniform element distribution, and demonstrate the enhanced electrochemical properties compared to the pure silicon , Si@TiO 2 and Si/NC materials when the composite materials are used as anodes for lithium-ion batteries, in which the Si@TiO 2 /NC composite anodes display the favorable initial coulombic efficiency of 75.9%, remarkable charge specific capacity of 1070.9 mAh g −1 with the coulombic efficiency approaching 100% after 100 cycles under the test current of 200 mA g −1 , extraordinary rate and cycle capability with the charge specific capacity of 696.2 mAh g −1 under the test current of 3000 mA g −1 and increased lithium ion diffusion coefficient from 8.179 E-12 cm 2 s −1 to 8.995 E-12 cm 2 s −1 after 100 cycles. Those excellent electrochemical properties can be attributed to the synergistic effect of the robust TiO 2 skeleton and the elastic conductive N-doped carbon network, indicating the as-prepared Si@TiO 2 /NC composite could be a promising anode for lithium-ion batteries.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2024
·
IF 20.2
Mengqing Hu,Di Zhao,Xinlong Yan,Yun Wang,Jin Zhang,Xiaoyan Hu,Ming Zhou,Porun Liu
Designing advanced bimetallic catalysts is essential to improving peroxymonosulfate (PMS) activation. Herein, a novel magnetic nickel/cobalt-layered double hydroxide decorated nitrogen-doped carbon (Ni/Co LDH@NC) catalyst we synthesized using carbonized ZIF-67 as a template for simultaneous removal of sulfamethoxazole (SMX) and Pb(Ⅱ) by PMS activation. The synthesized Ni/Co LDH@NC achieved complete degradation of SMX within 20 min and adsorbed Pb(Ⅱ) at 90.3 mg g −1 in 2 h. Notably, in simulated mixed wastewater, Ni/Co LDH@NC removed 100 % of SMX and simultaneously absorbed 84 % of Pb(Ⅱ) within 60 min. Density functional theory (DFT) studies revealed that synergistic Ni-Co sites and “bridging oxygen” vacancies enhanced electron transfer to PMS, facilitating O-O bond cleavage. The catalyst maintained high performance after four cycles, with over 85 % SMX degradation and 80 % Pb(Ⅱ) removal. This study highlights the potential of MOF-derived catalysts for efficient, simultaneous remediation of antibiotic and heavy metal pollutants, contributing to advanced wastewater treatment.
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