SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Renjie Li,Anli Chen,Qunfen Deng,Yujia Zhong,Ling Kong,Rui Yang
In this work, using melamine and MXene powder as precursors, NH 4 Cl as a template, a novel S-scheme heterojunction composite material g-C 3 N 4 /C-TiO 2 was synthesized by a one-step calcination method. During the calcination process, the gas template NH 4 Cl played a dual role, which not only striped the massive g-C 3 N 4 into porous flakes with a larger specific surface area but also striped the agglomerated MXene derivatives (C-TiO 2 ) nanoparticles, making them bind more closely with g-C 3 N 4 . The charge separation efficiency and photocatalytic performance were greatly improved due to the formation of heterojunction and the larger specific surface area of the sample. Within 50 min, the g-C 3 N 4 /C-TiO 2 exhibited high photocatalytic performance toward ciprofloxacin hydrochloride (CIP·HCl) with degradation efficiencies of 88.14% under visible light (λ ≥ 420 nm), which was 8.9 times higher than that of pure g-C 3 N 4 . In addition, we also used a series of characterizations to confirm the mechanism of S-scheme heterojunction and inferred the possible CIP photodegradation pathway.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
CHEMOSPHERE
·
2021
·
IF 7.086
Yang Liu,Zhuofeng Hu,Jimmy C. Yu
Doping heterogeneous atoms into BiOX is recognized as an effective method to improve its photocatalytic activity. Here, S-doped BiOBr (S–BiOBr) was synthesized via a solvothermal method in the absence of water, which is supposed to substitute O as S 2− in the lattice. This material is firstly used for the visible-light-driven degradation of ibuprofen, a model anti-inflammatory drug. The degradation efficiency of S–BiOBr is much higher than that of pure BiOBr. The degradation kinetic constant for S–BiOBr (2.48 × 10 −2 min −1 ) is about 3 times as high as that of pure BiOBr (0.83 × 10 −2 min −1 ). It is found that S-doping tunes the band structure of BiOBr, leading to a narrower band gap and thus higher utilization efficiency of visible light. The degradation of ibuprofen on S–BiOBr can be attributed to the generation of H 2 O 2 and OH radicals. OH radical plays a synergistic role along with holes in the photocatalytic degradation process, which is supposed to be better than the reported single hole- or superoxide-dominant reaction. This work reveals a previously unrecognized and more efficient method for the degradation of organic contaminants on BiOBr.
研究领域:
环境科学
·
材料科学
·
化学工程
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DOI
PubMed
高影响因子
DRUG METABOLISM AND DISPOSITION
·
2016
·Vol. 44
·期 4
·607-615
·
IF 3.21
Kai Wang,Hui Wang,Ying Peng,Jiang Zheng
Benzbromarone (BBR) is a benzofuran derivative that has been quite useful for the treatment of gout; however, it was withdrawn from European markets in 2003 because of reported serious incidents of drug-induced liver injury. BBR-induced hepatotoxicity has been suggested to be associated with the formation of a quinone intermediate. The present study reported epoxide-derived intermediate(s) of BBR. An N-acetylcysteine (NAC) conjugate derived from epoxide metabolite(s) was detected in both microsomal incubations of BBR and urine samples of mice treated with BBR. The NAC conjugate was identified as 6-NAC BBR. Ketoconazole suppressed the bioactivation of BBR to the epoxide intermediate(s), and the CYP3A subfamily was the primary enzyme responsible for the formation of the epoxide(s). The present study provided new information on metabolic activation of BBR.
研究领域:
药理学
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毒理学
·
药物代谢
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DOI
PubMed
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2019
·
IF 3.074
Qingquan Tang,Weiyi Zhang,Jiayin Yuan,Qiang Zhao
Charged cyclic polymers, e.g. cyclic DNAs and polypeptides , play enabling roles in organisms, but their synthesis was challenging due to the well-known “polyelectrolyte effect”. To tackle the challenge, we developed a templated method to synthesize a library of imidazolium and pyridinium based cyclic poly(ionic liquid)s. Cyclic templates, cyclic polyimidazole and poly(2-pyridine), were synthesized first through ring-closure method by light-induced Diels−Alder click reaction. Through quaternization of cyclic templates followed by anion metathesis, the cyclic poly(ionic liquid)s were synthesized, which paired with varied counter anions.
研究领域:
高分子化学
·
有机合成
·
功能材料
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离子液体
·
生物医用材料
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DOI
高影响因子
PHYSICAL REVIEW B
·
2014
·Vol. 90
·期 21
·214520
·
IF 3.664
X. F. Lu,N. Z. Wang,X. G. Luo,G. H. Zhang,X. L. Gong,F. Q. Huang,X. H. Chen
A series of $({\mathrm{Li}}_{0.8}{\mathrm{Fe}}_{0.2}){\mathrm{OHFeSe}}_{1\ensuremath{-}x}{\mathrm{S}}_{x}$ $(0\ensuremath{\le}x\ensuremath{\le}1)$ samples were successfully synthesized via hydrothermal reaction method and the phase diagram is established. Magnetic susceptibility suggests that an antiferromagnetism arising from $({\mathrm{Li}}_{0.8}{\mathrm{Fe}}_{0.2})\mathrm{OH}$ layers coexists with superconductivity, and the antiferromagnetic transition temperature nearly remains constant for various S doping levels. In addition, the lattice parameters of the both $a$ and $c$ axes decrease and the superconducting transition temperature ${T}_{c}$ is gradually suppressed with the substitution of S for Se, and eventually superconductivity vanishes at $x=0.90$. The decrease of ${T}_{c}$ could be attributed to the effect of chemical pressure induced by the smaller ionic size of S relative to that of Se, being consistent with the effect of hydrostatic pressure on $({\mathrm{Li}}_{0.8}{\mathrm{Fe}}_{0.2})\mathrm{OHFeSe}$. But the detailed investigation on the relationships between ${T}_{\mathrm{c}}$ and the crystallographic facts suggests a very different dependence of ${T}_{\mathrm{c}}$ on anion height from the Fe2 layer or $Ch\ensuremath{-}\mathrm{Fe}2\ensuremath{-}Ch$ angle from those in FeAs-based superconductors.
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DOI
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2018
·Vol. 25
·期 6
·1-9
·
IF 1.434
Yang Xiao,Chen Xiaoyan,Duan Lian,Ran Xiaoqi
Poly(1,3,4-oxadiazole)s (POD) was a kind of thermally stable fiber. However, its photostability was not good enough in practical application. Although some methods, such as synthetic modification or treatment by using polyhedral oligomeric silsesquioxane, were used to improve photostability of POD, the procedure was too complicated or costly. In this work, the photostability of POD fiber was improved by adhered iron trihydroxide (Fe(OH) 3 ) through coordination bond, which was a relatively simple method. The ferric chloride (FeCl 3 ) was easily adhered to surface of POD fiber by dipping method and then Fe(OH) 3 formed by treatment with sodium hydroxide (NaOH) solution. The existence of Fe(OH) 3 and formation mechanism were proved by XPS, SEM-EDS and FTIR, and the homogeneousness was observed by SEM. Results of XPS and FTIR measurements suggested that the adherence driving force was coordination bond. SEM characterization illustrated that the adherence was quite homogenous. The ability of UV-absorption of Fe(OH) 3 , which was confirmed by UV-spectra, could protect poly(1,3,4-oxadiazole)s fiber from photodegradation. The effect of protection was testified by mechanical testing. The results indicated that the Fe(OH) 3 can improve photostability of poly(1,3,4-oxadiazole)s fiber effectively.
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产品关联
DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2018
·
IF 2.975
Wen Yang,Shengnan Wang,Ran Li,Jian Xu,Wentao Hao
A growing interest has been devoted to the mechano-responsive fluorescent polymers recently for their potential applications in mechanosensors, memory devices, security papers, etc. In this article, we demonstrated that hyperbranched poly(amido amine)s (HPAMAMs) are novel mechano-responsive fluorescent polymers. The fluorescence intensity of HPAMAM films sensitively increases as the films stretch, both for small and large strains. After the strain is released, the fluorescence intensity of HPAMAMs can quickly return to nearly original values. Moreover, the fluorescence intensity of HPAMAMs continuously changes when experiencing cyclic stretching and releasing. It is believed that this work provides a new insight for the research of mechano-responsive fluorescent polymers.
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产品关联
DOI
高影响因子
CATALYSIS LETTERS
·
2019
·Vol. 149
·期 11
·2973-2983
·
IF 2.372
Luo Wei,Du Hui-Jun,Bonku Emmanuel Mintah,Hou Ya-Li,Li Ling-Ling,Wang Xiao-Qiang,Yang Zhong-Hua
Abstract Enantiopure alcohols have received much attention due to their widespread use as pharmaceutical intermediates. In the asymmetric biosynthesis of enantiopure alcohols, the excellent performance of carbonyl reductase makes it be the best choice as the biocatalysts. In this work, an alkali-tolerant carbonyl reductase ( Bs CR, encoded by yueD ) from Bacillus subtilis (strain 168) was obtained through gene mining, and successfully heterologously expressed in Escherichia coli with pET-32a. Bs CR showed excellent alkali resistance and even can keep more than 70% of its peak activity after incubation in Tris–HCl buffer at pH 9.0 for 40 h. The Michaelis constants and maximal velocity of the Bs CR to NADPH (A) and ethyl 4-chloroacetoacetate (B) are \(K_{m}^{A}\) = 5.390 × 10 −2 mmol/L, \(K_{m}^{B}\) = 1.855 mmol/L, and \(V_{max}\) = 147.3 μmol·min −1 ·mg −1 , respectively. Applying the E. coli BL21(DE3)/pET-32a-yueD to catalyze asymmetric reduction of ethyl 4-chloroacetoacetate and acetophenone, the yield of S -CHBE reached 89.9% and S -1-phenyl ethanol reached 66.7%, and e.e. of both products reached more than 99%. This work provides a novel CR for asymmetric reduction. Graphic Abstract A carbonyl reductase ( Bs CR) and its gene were identified through gene mining, and overexpressed in Escherichia coli BL21(DE3) for whole-cell biocatalytic asymmetric reduction
研究领域:
生物技术
·
生物化学
·
药物科学
·
酶学
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Xuan Zhou,Lei Yuan,Zongbao Sun,Wen Zhang
Residual organophosphorus pesticides (OPs) frequently contaminate farm products, such as vegetables, and consequently threaten food safety. Herein, we present an enzyme-regulated dual-emission probe, MIL-53-OPH@S-S-AuNCs, for synchronous OPs hydrolysis and fluorescence determination. The probe, containing NH 2 -MIL-53(Al), organophosphorus hydrolase (OPH), and disulfide-functionalized Au nanoclusters (S-S-AuNCs), thus provides two emissive outputs (F 427 and F 655 ). Specifically, an OPH-assisted hydrolysis route is designed, where OPs are converted into class-informative products, including p-nitrophenol (PNP) and thiol/thiolate species (R-SH/S - ). PNP induces pronounced quenching of the blue emission (F 427 ) via resonance energy transfer, while sulfur-containing products perturb the disulfide-crosslinked state of S-S-AuNCs and attenuate the red emission (F 655 ). Stepwise optimizations are performed to promote efficient catalytic conversion and stable dual-channel readout, where quenching time, pH, and temperature are tuned to achieve pleasurable sensing conditions. This method provides log-linear quantification for OPs in a wide range of 6.5 × 10 −6 ∼20 μg mL −1 , with an impressive limit of detection of 3.4 × 10 −6 μg mL −1 . The proposed method is further validated by natural sample analyses and recovery tests in real vegetables, giving relative errors of 4.2∼8.6% and recoveries of 96.2∼105.2%.
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DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2023
·
IF 5.1
Zhengpeng Chen,Lei Wang,Yuanyuan Jin,Hongyun Guo,Yongdong Zhang,Mingzhong Ma,Xiaobo Wang,Xing Zhou,Ziqiang Lei,Dedai Lu
Gas therapy and embolization are important treatment methods for solid tumors. In order to improve the efficacy of NO therapy and simplify the operation of interventional embolization, we designed and prepared the microacidic-gelled poly[(L-Glutamic acid- ran -L-Tyrosine)- b -L-Threonine- b -L-S-nitrosocysteine]s (PGTTSNCs, obtained by the reaction of tert-butyl nitrite with thiol side groups of poly[(L-Glutamic acid- ran -L-Tyrosine)- b -L-Threonine- b -L-Cysteines]s, PGTTCs.) for noninterventional embolization combined with NO gas therapy for solid tumors. The results of in vivo experiments indicated that PGTTSNCs from PGTTCs-6.4 (the gelled-pH value is 6.4) has significant target-accumulation and therapy effects, and at 10 days post-injection only scars were found at the tumor site. After 20 days, the tumors of model mice were completely disappeared. The method is extremely simple and efficient for solid tumors, which is not only a great innovation of tumors theranostic, but also a qualitative development in nanomaterials .
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产品关联
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2017
·
IF 2.299
Misganaw Alemu Zeleke,Dong-Hau Kuo,Osman Ahmed Zelekew,Albert Daniel Saragih
Ge-substituted Cu 2 Sn(S,Se) 3 bulks with Cu 2 (Sn 1- x Ge x )(S,Se) 3 formula at x = 0, 0.25, 0.50, 0.75, and 1.0 were synthesized by reactive liquid phase sintering , where the heating process was held at 200 °C for 20 min before reaching the sintering temperature of 600 °C for 30 min. In the presence of volatile Sb 2 S 3 sintering aid , the effects on densification , grain boundary, crystalline size, and electrical properties of Ge-substitution were investigated. Cu 2 (Sn 1- x Ge x )(S,Se) 3 showed p-type behavior for all x values. It was found that the mobility was increased sharply and carrier concentration was decreased rapidly as the x -value was increased. The electrical conductivities were found to be 14.0, 22.7, 36.8, 126, and 153 S/cm at x = 0, 0.25, 0.50, 0.75, and 1.0, respectively. X-ray diffraction (XRD) peaks were shifted to the higher angle and band gaps increased upon successive increasing of the Ge/[Ge+Sn] fraction being 1.19, 1.21, 1.22, 1.24, and 1.26 eV at x = 0, 0.25, 0.50, 0.75, and 1.0, respectively. The studies of Ge-x-CTSSe bulks were based on Ge Sn defects and supported by the data of morphological, structural, electrical, and optical properties .
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产品关联
DOI
高影响因子
JOURNAL OF POWER SOURCES
·
2024
·
IF 8.1
Wenyi Wang,Long Tang,Cheng Chen,Xueqin Wang,Yuanyuan Wang,Wencong Sun
Efficient and stable electrocatalysts with low platinum content are crucial for the practical application of fuel cells. The development of Pt-based single atom catalysts (SACs) has emerged as a promising research direction. In this study, we design and prepare a SACs based on MoS 2 with Pt–S–Mo and Pd–S–Mo active sites (Pd, Pt–MoS 2 ) by successively occupying vacancies, while maintaining the individual characteristics of the active sites. The resulting Pd, Pt–MoS 2 catalyst exhibits excellent electrocatalytic activity for oxygen reduction reaction (ORR), long-term stability, and resistance to common poisons (SCN − , S 2− , and methanol) under neutral conditions. Meanwhile, the microbial fuel cell (MFC) equipped with Pd, Pt–MoS 2 exhibits excellent performance in terms of actual electricity generation performance and sewage purification capacity with an ultrahigh power density, average chemical oxygen demand (COD) removal rate, and coulombic efficiency (CE) of 1398.6 ± 43.5 mW m −2 , 96.2 ± 2.2 %, and 22.5 ± 0.5 %, respectively. This strategy will provide new insights into the development of advanced bimetallic as well as polymetallic doped vacancies of MoS 2 SACs.
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产品关联
DOI
高影响因子
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