MICROPOROUS AND MESOPOROUS MATERIALS
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2024
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IF 4.8
Ying Zhang,Qinqin Wang,Mingyuan Zhu,Bin Dai
The prevailing Zn/AC catalysts was plagued by limited lifetime and difficulties in regeneration for acetylene acetoxylation. In order to exploring renewable catalyst for acetylene acetoxylation, Zn/S-1 catalyst was synthesized using Silicalite-1(S-1) as support. The catalytic performance of Zn/S-1 was compared with Zn/AC catalyst using active carbon as support. The CH 3 COOH conversion of Zn/S-1 catalyst only decreased 15 % after running 225 h, much better than the 66 % of Zn/AC after 154 h. TG analysis revealed that the improved stability of Zn/S-1 catalyst was attributed to its better resistance for carbon deposition with the presence of S-1 support. A series of characterizations and DFT results elucidated that the Lewis acid sites of S-1 support and Zn component serve as dual active sites, which enhanced the adsorption of CH 3 COOH and inhibited the carbon deposition. In addition, the deactivated Zn/S-1 catalyst could be regenerated by calcination in air atmosphere due to the thermal stability of S-1, and the regenerated Zn/S-1 catalyst showed similar catalytic activity with the fresh catalyst.
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DOI
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STAR Protocols
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2024
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IF 1.3
Chunyang Xie,Dong Luo,Lu Liu,Xue Huang,Shao-Lin Zhang,Aimin Yang
Summary S -acylation of proteins allows their association with membranes. Here, we present a protocol for establishing a platform for membrane affinity evaluation of S -acylated proteins in vitro . We describe steps for preparing lipid-maleimide compounds, mCherry-p62 recombinant proteins, and total cellular membranes. We then detail procedures for synthesizing protein-lipid conjugates using lipid-maleimide compounds and recombinant proteins and evaluating the membrane affinity of protein-lipid conjugates. For complete details on the use and execution of this protocol, please refer to Huang Xue et al. 1
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DOI
PubMed
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Joule
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2023
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IF 39.8
Yatao Liu,Linhan Xu,Yongquan Yu,MengXue He,Han Zhang,Yanqun Tang,Feng Xiong,Song Gao,Aijun Li,Jianhui Wang,Shenzhen Xu,Doron Aurbach,Ruqiang Zou,Quanquan Pang
The transition from dissolution-precipitation to quasi-solid-state sulfur reaction promises restricted polysulfide shuttle and lean electrolyte operation of Li-S batteries but incurs poor reaction kinetics. We here demonstrate that structural reorganization of sparingly solvating electrolytes (SSEs)—which is uniquely afforded by using low-density and low-cost aromatic anti-solvents—is vital for taming the quasi-solid-state sulfur reaction. Aromatic anti-solvents disrupt the interconnected structure of concentrated tetrahydrofuran (THF) electrolyte, uniquely creating subdomains that act to dissolve elemental sulfur, thus accelerating its consumption and re-formation while maintaining ultralow polysulfides solubility. The altered subdomains further result in robust solid electrolyte interphase (SEI) on lithium metal. As a result, the Li-S cell with a 3 mg sulfur cm −2 sulfur cathode can cycle steadily for ∼160 cycles with a lean electrolyte of 5 μL mg sulfur −1 . Our work provides new insights into fine-tuning the electrolyte microstructure through solvent innovations for developing sulfur-based batteries that are high energy, cheap, and durable.
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DOI
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Cell Death Discovery
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2026
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IF 10.4
Wei Ziyi,Wu Ren,Ruan Jiawen,Yang Jiahe,Fu Xinxin,Li Yashi,Jiao Lijie,Xiang Lifei,Yu Dan,Yan Guoliang,Zhang Lili,Li Hongzhu
Diabetic vasculopathy represents one of the most serious complications of type 2 diabetes mellitus (T2DM). Growing evidence suggests that its pathogenesis is closely linked to chronic inflammation-driven phenotypic switching of vascular smooth muscle cells (VSMCs), which under hyperglycemic conditions exhibit heightened proliferative and migratory activity. While hydrogen sulfide (H₂S) is known for its antioxidant and anti-inflammatory roles in diabetic vasculopathy, the specific mechanisms by which H₂S alleviates these abnormal VSMCs phenotypes in T2DM remain unclear. Using T2DM mice and mouse aortic vascular smooth muscle cells (MOVAS) cultured under high-glucose-high-fat (HGHF) conditions, we observed a marked decrease in both the expression of the H₂S-synthesizing enzyme cystathionine γ-lyase (CSE) and endogenous H₂S production. These changes were accompanied by elevated oxidative stress, activation of the NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome, and enhanced MOVAS proliferation and migration. Notably, the H₂S donor NaHS reversed these changes. Further investigation into protein S-sulfhydration revealed that H₂S promotes the S-sulfhydration of thioredoxin reductase 1 (TrxR1). Through pharmacological inhibition and rescue experiments, we demonstrated that H₂S mediates S-sulfhydration at the Cys611 residue of TrxR1, thereby regulating its enzymatic activity and influencing the thioredoxin 1 (Trx1)–thioredoxin-interacting protein (TXNIP)–NLRP3 signaling axis. This process leads to suppression of inflammasome activation and contributes to the antioxidant, anti-inflammatory, anti-migratory, and anti-proliferative effects observed in MOVAS. Our study reveals a novel pathway whereby H₂S alleviates diabetic vascular complications via TrxR1 S-sulfhydration at Cys611 and subsequent inhibition of the Trx1–TXNIP–NLRP3 axis, highlighting a promising therapeutic target.
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SOLID STATE IONICS
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2016
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IF 2.38
Qingsong Wang,Jing Guo,Tian Wu,Jun Jin,Jianhua Yang,Zhaoyin Wen
A carbon coating layer facing sulfur cathode is introduced on one side of the solid state ionic conductor in the ceramic-liquid hybrid electrolyte based Li-S cell. Both the cycling performance and the rate capability are improved as a result of enhanced electron transport for the conversion of the dissolved sulfur-containing active materials as well as the wettability of the ceramic electrolyte towards the liquid electrolyte . The interface modified hybrid Li-S cell exhibits an initial discharge capacity of 1409 mA h g − 1 and remains at 1000 mA h g − 1 which is 235 mA h g − 1 higher than the pristine one, after 50 cycles at 0.2C rate.
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DOI
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JOURNAL OF CATALYSIS
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2022
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IF 8.047
Shengxin Chen,Yingwei Li,Zicheng Wang,Ying Jin,Ruixia Liu,Xingang Li
Hollow structure nanoreactors take advantage of catalyst loading and enhanced activity by shell construction. In this work, functionalized poly(ionic liquid)s (PILs) with hollow spherical structures were synthesized by polymerization- and quaternization-based approaches. These hollow structure PILs (HPILs) could be controllable designed from IL monomer easily, giving HPILs various properties. In the subsequent selective oxidation of cyclohexane , the HPILs acting as nanoreactors could efficiently improve the activity of metal salt catalysts (CoCl 2 ) and displayed adjustable selectivity for cyclohexanone, cyclohexanol (KA) or adipic acid (AA) by different types of HPILs. In kinetic study , it follows first-order reaction kinetics which CoCl 2 /HPIL-C12 had a lower the activation energy of 29.1 kJ/mol. Importantly, these nanoreactors storing the catalysts could be recovered and reused more than 7 times without significant loss of activity. A theoretical model for the hollow spherical reactor was further established to support the advance of the HPILs reactor, which could also help to predict reaction process in other core-shell catalytic system. Due to controlled substrate transfer and enhanced radical generation in HPILs, the reaction process could be adjusted to enhance the conversion of cyclohexane and selective oxidation to AA.
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ELECTROCHIMICA ACTA
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2021
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IF 6.901
Hong Li,Feng Shao,Xinzhu Wen,Yusen Ding,Chao Zhou,Yafei Zhang,Hao Wei,Nantao Hu
Developing scalable and facile techniques to design and construct unique structures of cathodes with high performance is challenging for the practical Li-S batteries. In this work, highly effective and scalable cathodes based on curved graphene/MXene bi-nanosheets-constituted fibers is demonstrated for long-lifetime Li-S batteries. Wet-spinning is introduced to design and fabricate sulfur cathodes based on graphene/MXene hybrid fibers, in which sulfur is uniformly distributed and intimately enveloped between graphene and MXene nanosheets. The high chemical affinity towards polysulfides enabled by MXene is demonstrated by experiments and density functional theory (DFT) calculations. The assembled cells show high sulfur utilization (the discharge capacity of 1483.1 mAh g −1 at 0.1 C), high rate performance (733.3 mAh g −1 at 2 C) and excellent long cycle stability (0.043% per cycle decay at 1 C over 1000 cycles). Moreover, a reversible areal capacity of 5 mAh cm −2 is achieved under a high sulfur loading of 5.6 mg cm −2 , revealing its great potential for practical applications. This study gives a valuable guidance to design advanced sulfur cathodes for high-performance Li-S batteries.
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ACS Applied Materials & Interfaces
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2021
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IF 9.229
Xiaoqing Ming,Changgeng Zhang,Junjie Cai,He Zhu,Qi Zhang,Shiping Zhu
The rapid development of soft electronics has revitalized the research of conducting elastomers. However, the design of conducting elastomers having high stretchability and good transparency still remains a considerable challenge. In this study, we develop a highly transparent, stretchable, and conducting ionoelastomer based on a poly(ionic liquid) in which cations are fixed to a stretchable elastomeric network and counter anions are mobile. The ionoelastomer solves the dilemma of simultaneous transparency and stretchability in the design of traditional conducting elastomers, possessing good transparency (96%) with an extraordinarily high stretchability, up to a limiting strain of 1460%. Moreover, this novel material is completely nonvolatile and nonhygroscopic, endowing the ionoelastomer with highly stable thermal, environmental, electrochemical, and mechanoelectrical properties. An underwater sensor based on the ionoelastomer is developed with good performance in an aqueous environment. Also, a transparent dielectric elastomer actuator (DEA) is demonstrated using the ionoelastomer. It is believed that the ionoelastomer would pave the way to develop exceptional conducting elastomers toward next-generation soft electronics.
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DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
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2022
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IF 7.392
Cai Qi,Shu Zu,Xukun Zhu,Tong Zhang,Longyan Li,Li Song,Yachao Jin,Mingdao Zhang
Functional and active carbon material is of great concern in facilitating the performance of lithium-sulfur (Li-S) battery . In this work, we develop a bamboo-like nitrogen-doped carbon nanotubes (Co@NCNTs-2) with low cobalt metal content, which acts as not only the host matrix for sulfur loading but also an efficient catalyst for the adsorption and conversion of lithium polysulfides (LiPSs). The characterization results show that the Co particles are mainly encapsulated inside the Co@NCNTs-2, and the N species are mainly distributed on the outer surface of Co@NCNTs-2. The Co particles are the growth sites of carbon nanotubes and are wrapped by carbon to form Co@NCNTs-2. It is confirmed that the uniform graphitized structure contributes to charge transfer, while the enriched N species assist the trap and catalytic conversion of the polysulfides, thus helping to restrain the shuttle effect. As a result, the resultant Co@NCNTs-2-S cathode presents high reversible capacity at different current densities and exhibits superior cycling stability for 300 cycles at 0.5 C.
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DOI
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2025
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IF 6.1
Ke Zhang,Xing Zhang,Yaopeng Zheng,Binquan Wang,Xiaoyan Zhang,Yuanyuan Song,Xiaoxiao Luo,Mingkuan Sun
Bisphenol S (BPS), a widely used substitute for Bisphenol A (BPA), has been implicated in neurodevelopmental disorders by numerous studies. While BPS has been known for neurodevelopmental disturbance, the analysis and molecular mechanisms underlying the neurotoxicity are not completely understood. This study utilizes a Drosophila model to investigate the developmental neurotoxicity of BPS and its underlying molecular mechanisms. The results demonstrate that BPS exposure significantly induces abnormal behaviors in Drosophila , including social interaction deficits, increased self-grooming, and impaired locomotor activity. Moreover, BPS disrupts axonal development, leading to abnormal α and β lobes in the mushroom body (MB) and structural damage in the neuromuscular junction (NMJ). NMJ defects are marked by reductions in area, length, perimeter, bouton number, branching, and overall morphological integrity. A genome-wide association study (GWAS) identified Lar as a key mediator of BPS-induced neurotoxicity. Molecular docking simulations and Western blot analyses further confirmed that BPS interferes with the cytoplasmic functions of Lar . Notably, neuronal overexpression of Lar ’s cytoplasmic domain rescued MB and NMJ defects and mitigated BPS-induced behavioral abnormalities. These findings suggest that BPS impairs Lar function, thereby disrupting MB and NMJ morphology and ultimately inducing abnormal behaviors in Drosophila .
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PubMed
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
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2025
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IF 3
Feng Tianxu,Shan Wei,Zhang Yongzhou,Huang Haibo,Tang Hua
Solar photocatalytic degradation and adsorption using metalorganic frameworks (MOFs) offer safe and energy-efficient remediation for water contaminated with small organic pollutants, leveraging their semiconductor-like tunable band structures and inherent porosity. This study reports the de novo synthesis of a visible-light-responsive Ti@Ce MOF heterojunction composite for synergistic photocatalytic degradation and adsorption of recalcitrant organic contaminants. An in-situ growth strategy deposited NO.-functionalized UiO-66(Ce) onto NH 2 -modified MIL-125, forming an S-scheme heterojunction engineered for efficient visible-light-driven hydrogen peroxide (H 2 O 2 ) generation. This in-situ photogenerated H 2 O 2 acts as a potent oxidant, effectively degrading tetracycline. A significantly enhanced photocatalytic degradation rate constant ( k ) for tetracycline was observed, indicating boosted catalytic activity. Mechanistic analysis underscores the critical role of the S-scheme heterojunction in promoting charge carrier separation and enhancing H 2 O 2 production, thereby efficiently driving organic pollutant oxidative degradation. This work provides a novel strategic framework for designing multifunctional MOF composites, advancing high-performance, sustainable water purification technologies.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2024
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IF 9.4
Ya-Nan Jing,Xing-Liang Yin,Lei-Lei Li,Yan-Lan Wang,Jia Xue,Ze-Feng Xu,Da-Qiang Liu,Chuan-Wu Chen,Xiao-Jie Liu,Er-Kang Liu
CO 2 -to-high value-added chemicals via a photocatalytic route is of interest but strangled by the low efficiency. Herein, a novel Fe-TiO 2-x /TiO 2 S-scheme homojunction was designed and constructed by using a facile surface modification approach whereby oxygen vacancy (OV) and Fe introducing on the TiO 2 nanorod surface. The as-synthesized Fe-TiO 2-x /TiO 2 S-scheme homojunction exhibits positive properties on promoting photocatalytic CO 2 reduction: i) the nanorod structure provides numerous active sites and a radical charge transfer path; ii) the doped Fe and OV not only synergistically enhance light utilization but also promote CO 2 adsorption; iii) the Fe-TiO 2-x /TiO 2 S-scheme homojunction benefits photoexcited charge separation and retains stronger redox capacity. Thanks to those good characters, the Fe-TiO 2-x /TiO 2 homojunction exhibits superior CO 2 reduction performances with optimized CO/CH 4 generation rates of 122/22 μmol g -1 h −1 which exceed those of pure TiO 2 by more than 9.4/7.3 folds and most currently reported catalytic systems. This manuscript develops a facile and universal approach to synthesize well-defined homojunction and may inspire the construction of other more high-efficiency photocatalysts toward CO 2 reduction and beyond.
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PubMed
高影响因子
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