JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
·
2018
·Vol. 56
·期 22
·2574-2583
·
IF 2.588
Zhangxin Chen,Chang Su,Xiaogang Zhu,Ruoteng Xu,Lihuan Xu,Cheng Zhang
A novel organic conjugated polymer based on star-shaped triazine-functional triphenylamine framework poly[1,3,5-tris(4-diphenylamino-phenyl)triazine] (PTDAPTz) is designed and synthesized successfully by FeCl 3 -catalysted chemical oxidative polymerization. The polymer PTDAPTz powder exhibits a compactly packed pleated skirt shape-like morphology with a high surface area (~930 m 2 g −1 ) and a bimodal pore size distribution ranging from micropores (~0.55 nm) to small diameter mesopores (~2–6 nm). As explored as the cathode material, the obtained PTDAPTz presents the double charge–discharge process characteristics of both the free radical redox of triphenylamine unit and the bipolar redox of triazine unit in the polymer and a well-defined multistage charge/discharge voltage plateau (~3.8 V for p-doped and ~2.0 V for n-doped) during the charge–discharge process. Also, the PTDAPTz demonstrates an improved capacity (stabilized at 123 mA h g −1 until 50th cycle) and the enhanced rate performance compared to polytriphenylamine (PTPAn). Specially, the discharge curve for the part of triphenylamine unit presents an obviously improved discharge plateau (~3.8 V for PTDAPTz compared to ~3.6 V for PTPAn) due to the electron-withdrawing effect of the triazine unit to triphenylamine. The elaborate structural design and created micro-/mesoporous morphology with the double charge–discharge process make PTDAPTz a potential candidate as the performance-improved cathode of Li-organic battery. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018 , 56, 2574–2583
研究领域:
材料科学
·
电化学
·
有机合成
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DOI
高影响因子
Soft Matter
·
2018
·Vol. 14
·期 36
·7420-7428
·
IF 3.709
Dinglei Zhao,Quan Tang,Qiang Zhou,Kang Peng,Haiyang Yang,Xingyuan Zhang
As one of the most promising biomaterials, injectable self-healing hydrogels have found broad applications in a number of fields such as local drug delivery. However, controlled release of drugs in hydrogels is still difficult to realize up to now. Here, we report a novel photo-degradable injectable self-healing hydrogel based on the hydrophobic interaction of a biocompatible four-arms star polymer, poly(ethylene glycol)-b-poly(γ-o-nitrobenzyl-L-glutamate). The hydrophobic interaction between poly(γ-o-nitrobenzyl-L-glutamate) not only connects poly(ethylene glycol)-b-poly(γ-o-nitrobenzyl-L-glutamate) together with a crosslink but also provides a hydrophobic domain to encapsulate hydrophobic pharmaceuticals such as doxorubicin (DOX). Due to the dynamic character of the hydrophobic interaction, the hydrogel exhibits excellent injectable and self-healing ability. In particular, the photolabile o-nitribenzyl ester group is cleaved under UV irradiation. As a result, the hydrophobic domain transforms into the hydrophilic one and the embedded DOX is released effectively. An increasing release ratio of DOX dramatically enhances the apoptosis ratio of HeLa cells. We expect these attractive properties may be beneficial to practical applications of the hydrogel as an effective local drug delivery means in a truly physiological environment.
研究领域:
生物医学工程
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药学
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材料科学
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DOI
PubMed
高影响因子
ACS Applied Polymer Materials
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2026
·
IF 5.2
Jakkree Intranuwong,Arin Kim,Nutcha Nongyai,Seong Kyu Shin,Yong Ku Kwon
Porous polymeric biodegradable monoliths (PHIPEn, where n denotes the number of arms of the PLA macroinitiator) based on poly(δ-valerolactone-co-l-lactide) were prepared via bulk ring-opening polymerization of a δ-valerolactone/l-lactide (VL/LA) eutectic mixture (80/20) using various PLA macroinitiators. Linear (one- and two-arm) or star-shaped (four- and six-arm) PLA macroinitiators were employed to investigate the effect of initiator functionality on the morphology and properties of PHIPEns. The variation in initiator functionality strongly affected the pore morphology, cross-link density, and overall physical properties of the materials. Increasing the number of arms resulted in smaller pore size, higher cross-link density, greater crystallinity, and improved compressive strength and modulus. Thermal analysis revealed that PHIPEns prepared from star-shaped macroinitiators exhibited improved thermal stability and higher PVL crystallinity compared with those derived from linear macroinitiators. Hydrolytic degradation in phosphate-buffered saline at 37 °C showed that PHIPEns synthesized from star-shaped macroinitiators degraded more slowly, absorbed less water, and maintained a more stable pH than those derived from linear ones. These results demonstrate that combining star-shaped macroinitiators with a VL/LA eutectic mixture provides an effective strategy for designing biodegradable porous materials with tunable properties.
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高影响因子
THERIOGENOLOGY
·
2026
·
IF 2.9
Jiahao Zhao,Xiangyu Zhou,Baoyi You,Bowen Cheng,Jiashuo Hu,Yuxuan Lu,Dianrui Xu,Xiwei Zhang,Chunlong Yan,Qingshan Gao,Haixing Liu,Qingguo Jin
Florfenicol (FLO) is widely used to treat bacterial respiratory diseases and hoof rot in cattle at various physiological stages. However, residues of FLO that accumulate in cattle may have adverse effects on animal health. Although FLO has been reported to exhibit embryotoxic and cytotoxic properties, the mechanism underlying its effects on bovine granulosa cells (GCs) remains poorly understood. In this study, we treated GCs with FLO at concentrations of 0, 10, and 100 μg/mL for 48 h to evaluate the effects of FLO on cell viability, mitochondrial function, and steroid hormone synthesis. The results showed that FLO treatment was associated with increased apoptosis, reduced GC proliferation, and impaired mitochondrial function. In addition, FLO treatment was accompanied by decreased ATP levels and increased intracellular reactive oxygen species (ROS). Furthermore, FLO exposure was associated with changes in PROG and E2 production, decreased protein expression of StAR and CYP11A1, and reduced levels of adenylate cyclase (AC), cyclic adenosine monophosphate (cAMP), and protein kinase A (PKA). The antioxidant N-acetyl-L-cysteine (NAC) partially attenuated these changes. In conclusion, our findings suggest that FLO exposure is associated with GC dysfunction and impaired steroidogenesis. These effects may be related to oxidative stress, mitochondrial dysfunction, and alterations in the cAMP/PKA/StAR signaling pathway, although direct causal relationships remain to be further elucidated.
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PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.7
Xiaofei Sun,Ning Chen,Shujun Wang,Yushu Lin,Jie Zhang,Shuo Xing,Qing Liu,Yueyun Li,Daopeng Zhang,Kai Feng,Jongnam Park,Feng Tang
Cardiac troponin I (cTnI), recognized as the gold-standard biomarker for acute myocardial infarction (AMI), plays a crucial role in the early diagnosis and clinical management. Herein, we present a rationally designed multiple signal enhancement strategy for an ultrasensitive electrochemical immunoassay of cTnI. This work integrates the superior catalytic activity of a wrinkled MoS 2 -supported PtAgCu ternary alloy (PtAgCu/MoS 2 ) with the excellent conductivity of hexagonal star-like nitrogen-doped carbon (HS-NC) modified by gold nanoparticles (Au@HS-NC). The PtAgCu alloy, featuring maximized atomic utilization and optimized d-orbital coupling, exhibits outstanding hydrogen peroxide (H 2 O 2 ) electroreduction activity and a large electrochemically active surface area, thereby effectively amplifying the sensing signal. Meanwhile, the precisely designed MoS 2 carrier not only offers abundant anchoring sites and facilitates charge transfer but also enriches H 2 O 2 reactant, thereby promoting the catalytic performance of the PtAgCu alloy. Furthermore, as an ideal substrate, the morphologically engineered HS-NC, enriched with nitrogen functionalities, offers a highly conductive framework with ultralarge surface area (1121.80 m 2 g −1 ), enabling efficient immobilization of primary antibodies (Ab 1 ) and stable, accelerated charge transfer, thereby synergistically amplifies the signal output. Benefiting from this multiple amplification strategy, the proposed immunosensor achieves a remarkably low limit of detection of 0.51 fg mL −1 , and an exceptionally broad dynamic range (from 10 fg mL −1 to 100 ng mL −1 ), while exhibits excellent selectivity in complex matrices, maintaining high reproducibility and stability. This work demonstrates a rational multi-amplification design paradigm for constructing high-performance immunosensors and highlights its promising application in AMI early diagnosis.
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DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Hongji Jiang,Zhong Wang,Bing Mao,Yan Bing,Ning Sun,Jie Yuan
To investigate the effects of steric hindrance fluorene and heavy-atom bromine on the general optoelectronic properties of star-shaped organic emitters based on 9-(2-cyanophenyl) carbazole ( OCzPhCN ) frameworks, heavy element of bromine and steric hindrance fluorene were introduced into OCzPhCN to produce four derivatives of 2-(3-bromo-9H-carbazol-9-yl)benzonitrile ( BrCzPhCN) , 2-(3-bromo-6-(9-(4-ethoxyphenyl)-9H-fluoren-9-yl)-9H-carbazol-9-yl)benzonitrile (BrFCzPhCN) , 2-(3-(9-(4-ethoxyphenyl)-9H-fluoren-9-yl)-9H-carbazol-9-yl)benzonitrile (FCzPhCN) and 2-(3,6-bis(9-(4-ethoxyphenyl)-9H-fluoren-9-yl)-9H-carbazol-9-yl)benzonitrile (2FCzPhCN) . The fluorene units obviously improve the thermal stability of the obtained compounds, and 2FCzPhCN has the highest thermal stability with 5 % mass heat loss temperature reaching 447 °C. In different polar solvents, the absorption peaks wavelength of OCzPhCN , FCzPhCN and 2FCzPhCN are basically unchanged, and the redshifted emission peaks are positively correlated with solvent polarity. The photoluminescence quantum yields (PLQYs) of OCzPhCN , BrCzPhCN , FCzPhCN , BrFCzPhCN and 2FCzPhCN powders were 20.17 %, 5.43 %, 30.75 %, 3.27 % and 23.56 %. The fluorescence and phosphorescent quantum efficiencies of OCzPhCN , BrCzPhCN, FCzPhCN , BrFCzPhCN and 2FCzPhCN powders are 9.76 % and 10.41 %, 1.2 % and 3.23 %, 28.45 % and 2.3 %, 3.27 % and 0 %, 23.56 % and 0 %. OCzPhCN , BrCzPhCN and FCzPhCN powders show obvious room temperature phosphorescent emission, and the phosphorescent emission lifetime of OCzPhCN , BrCzPhCN and FCzPhCN powders at 561 nm, 576 nm and 568 nm are 193.17 ms, 18.65 ms and 7.25 ms. Compared with OCzPhCN, the introduction of bromine decreases the PLQY and the phosphorescent lifetime of BrCzPhCN powder, while the fluorescence quantum efficiency of the compound FCzPhCN powder has been improved. The corresponding single-triplet energy splitting (ΔE ST ) of OCzPhCN , FCzPhCN and 2FCzPhCN in solutions are 0.49 eV, 0.63 eV and 0.63 eV, and the corresponding ΔE ST values of OCzPhCN, BrCzPhCN FCzPhCN powders are 1.19 eV, 0.74 eV and 0.55 eV. The steric hindrance fluorene units result in smaller and stabilized ΔE ST in the solid powder states, and the same situation is opposite in the unimolecular solutions. The maximum external quantum efficiency of organic light-emitting diode based on 10,10′-(4,4′-sulfonylbis (4,1-phenylene)) bis (9,9-dimethyl-9,10-dihydroacridine) hosted by OCzPhCN reaches 12.7 %, and the external quantum efficiency at 100 cd/m 2 rolls down to 11 %. OCzPhCN is the best emitters in terms of room temperature phosphorescent emission and host applications.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
PubMed
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2019
·
IF 3.074
Yang Zhou,Boni Wang,Yong Yang,Ruijing Li,Yufeng Wang,Ning Zhou,Jinyou Shen,Yong Zhou
Dicationic four-arm polymeric ionic liquid based on poly( N , N , N -trimethyl-N-((2-(dimethylamino)ethyl methacrylate)-7-propyl)-ammonium bis(trifluoromethanesulfonyl) imide) is prepared via atom transfer radical polymerization of 2-(dimethylamino)ethyl methacrylate and anion functionalization. A solid-state electrolyte comprising polymeric ionic liquid matrix, ionic liquid plasticizer and LiTFSI is subsequently developed. The solid-state electrolyte with star topology possesses high thermal stability up to 407 °C. The low T g and crystallinity endow the electrolyte with more amorphous structure and higher mobility of polymer segments. The ion conductivity of electrolyte based on four-arm polymer achieves 0.114 mS cm −1 at 30 °C, which is 42.5 times that of the linear counterpart. The electrochemical stability window and Li + transference number reach 4.9 V and 0.40, respectively. In combination with the superior interfacial characteristics between this four-armed electrolyte and lithium electrode, the assembled lithium metal cell delivers high discharge capacity of 165 mAh g −1 at 0.1C with 94% capacity retention over 100 cycles. The growth of lithium dendrites is effectively inhibited. It also presents a discharge capacity of 149 mAh g −1 at 0.5C, the capacity retention of which is 70% after 500 cycles. This design of dicationic scaffold with star topology provides a new orientation for developing high performance polymer electrolyte for practical applications.
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DOI
高影响因子
ULTRASONICS SONOCHEMISTRY
·
2025
·
IF 9.7
Silei Zhang,Qingbo Huang,Xiangmin Kuang,Chaofan Guo,Yongli Jiang,Fujie Zhang,Daihong Pan,Ming Du,Sakamon Devahastin,Junjie Yi
Conventional pretreatments of star anise ( Illicium verum Hook. f.) often result in uneven color development, long drying duration and substantial aroma losses, hence limiting final product quality and market value. To address these issues, the present study hypothesized that ultrasound-assisted electrolyzed water thawing (UEWT) as pretreatment prior to drying could accelerate drying and enrich flavor of star anise by inducing appropriate structural and biochemical changes. The effects of UEWT were compared with those of deionized water thawing (DWT), electrolyzed water thawing (EWT), ultrasound-assisted deionized water thawing (UDWT), and hot water blanching (HWB), with a focus on drying kinetics, microstructure, relevant enzyme activities, antioxidant activities and volatiles composition of star anise were evaluated. UEWT reduced drying time to 8 h, with the highest drying rate (0.75 kg/(kg·h)), free water content (48 %) and oil-associated NMR signal (23 %). Enhanced cell disruption enhanced moisture migration and volatiles release, while elevated PPO and POD activities intensified desirable coloration ( a* = 27.3; Δ E = 26.8); antioxidants retention was nevertheless compromised (phenolics 45.94 mg GAE/g; flavonoids 2.35 mg GAE/g). UEWT also resulted in the highest content of trans -anethole (1100.40 μg/kg) and formation of α-terpineol, both of which are key contributor to characteristic aroma of star anise. These findings demonstrate that UEWT effectively balances drying rate, color formation, and aroma retention, offering a practical pretreatment for quality-oriented drying of spice fruits. Future studies should optimize ultrasonic parameters and evaluate industrial-scale integration for continuous spice processing.
研究领域:
食品科学与技术
·
采后生理学
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超声加工
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植物生物化学
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干燥技术
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DOI
PubMed
高影响因子
POWDER TECHNOLOGY
·
2023
·
IF 5.2
Xuan Liu,Jie Gong,Kai Jiang,Xiaojuan Lai,Yu Tian,Kang Zhang
In order to reduce the apparent viscosity of lignite coal water slurries (CWSs) and improve its static stability, a series of three-arm amphiphilic block copolymers have been prepared through RAFT polymerization by using poly(ethylene glycol) methyl ether acrylate (PEGMA) and sodium 4-vinylbenzenesulfonate (SSNa) as hydrophilic monomers and styrene (St) as hydrophobic monomer. The chemical structure of the copolymers has been investigated, and the impact of relative molecular weight, hydrophilic/hydrophobic ratio, and ionic group content on the pulping performance of three-arm amphiphilic block copolymers has been examined. The lignite coal water slurries (CWSs) prepared from the block copolymer tri -P(St 50 - s -SSNa 50 ) 10K - b -PPEGMA 10K exhibit a remarkably low apparent viscosity of 395 mPa·s and excellent static stability when the coal content is at 55 wt% and dispersant content is at 0.5 wt%. Moreover, these CWSs can achieve a maximum pulping concentration of up to 59 wt%. Additionally, the thermogravimetric test reveals insights into the water occurrence in CWSs, indicating that higher levels of free water content correspond to lower apparent viscosities. Suitable hydrophobicity facilitates the removal of internal water from lignite by dispersants, disrupting its flocculation structure and promoting CWSs formation. Meanwhile, the presence of ionic groups enhances the static stability of the resulting CWSs. Furthermore, the adsorption behavior of the three-arm amphiphilic block copolymer dispersant in lignite has been analyzed through XPS testing to elucidate its dispersion mechanism. The use of three-arm amphiphilic block copolymers in preparing lignite CWSs results in lower apparent viscosity and improved static stability, attributed to the amphiphilic and steric hindrance effects of dispersants. This not only expands the application range of lignite CWSs but also highlights the significant potential of this type of dispersant.
研究领域:
聚合物化学
·
材料科学
·
能源工程
·
化工工程
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2023
·Vol. 140
·期 23
·e53905
·
IF 3
Xue Dong,Mengfei Long,Hongxia Liu,Ling Gao,Xinjie Xu,Xiaole Xia
Potential migration and toxicity limited applications of traditional plasticizers like bis(2-ethylhexyl) phthalate (DEHP) in food packing and medical machinery and so forth. Safe and feasible bio-based plasticizers have recently moved into the limelight of research hotspot. Here, we designed series polyester plasticizers of various branches with star-shaped poly(ε-caprolactone) (SPCLs) and net-shaped poly(ε-caprolactone) (NPCLs) structures by one-pot solvent-free synthesis with glycidol and polyglycerol as initiators. Structures of SPCLs and NPCLs were further verified by FTIR, 1 H NMR, and 13 C NMR. Moreover, the properties of the plasticizers and plasticized PVC were evaluated by differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), thermogravimetric analysis (TGA) and tensile test. PVC films plasticized with the SPCLs or NPCLs exhibited increased plasticizing effect, compatibility, flexibility and cold resistance. The lowest T g value of plasticized PVC samples (PVC/NPCL1-C4) was −45.3°C, which made the plasticization efficiency reach 122.5%. In particular, PVC/SPCLs-C4 (SPCL2-C4) had 107% higher elongation at break than PVC/DEHP. Meanwhile, the initial decomposition temperature T i value of the PVC blends maximum increased from 240 to 328°C when DEHP was completely replaced by SPCLs or NPCLs, indicating improved thermal stability of the plasticizer. Overall, “green” plasticizers with fining topological branch design would be promising to partially replace petroleum-based plasticizers.
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高影响因子
JOURNAL OF POWER SOURCES
·
2018
·
IF 6.945
Shi Wang,Ailian Wang,Chengkai Yang,Rui Gao,Xu Liu,Jie Chen,Zhinan Wang,Qinghui Zeng,Xiangfeng Liu,Henghui Zhou,Liaoyun Zhang
All-solid-state polymer electrolyte (SPE) matrices prepared by molecular design are still needed to be further perfected with excellent performance. In this paper, a controlled-structure discotic liquid crystal (DLC)-based six-arm star copolymer was designed and synthesized from a DLC initiator (2,3,6,7,10,11-hexakis(2-bromoisobutyryloxy)triphenylene) via the sequential atom transfer radical polymerization (ATRP) of styrene and poly(ethylene glycol) methyl ether methacrylate (PEGMA). Here, this class of discotic liquid crystal star polymer is applied as an SPE in LIBs for the first time. By solution casting , a suitable self-standing SPE film composed of the six-arm copolymer and lithium bis(trifluoromethanesulfonimide (LiTFSI)) can be easily formed, and the film shows long-range molecular orientation after annealing. It is confirmed that the electrolyte shows wide electrochemical window (5.1 V) and high lithium-ion transference number (0.37). Especially, the ionic conductivity (1.46 × 10 −4 , S cm −1 , 30 °C) of the obtained SPE is more than 8 times higher than that of the corresponding linear copolymer electrolytes. Furthermore, the results of battery performance demonstrate that the polymer electrolyte displays eminently reversible electrochemical reaction and outstanding cycling performance. The present work not only shows the advantages of DLC-based star SPE for LIBs but also paves the way for the design of SPE with excellent performances.
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高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2018
·
IF 3.997
Yong-E. Gao,Shuang Bai,Xiaoxiao Shi,Meili Hou,Xiaoqian Ma,Tian Zhang,Bo Xiao,Peng Xue,Yuejun Kang,Zhigang Xu
Nanomedicine based polymeric prodrug have showed high impact in the inhibition of tumor growth due to its high therapeutic efficiency and improved biocompatibility. Herein, we synthesized a novel star-like amphiphilic copolymer [β-CD–P(Ir- co -OEGMA), denoted as CPIO] through atom transfer radical polymerization (ATRP) to deliver the hydrophilic anticancer drug irinotecan (Ir). The polymer could form monodisperse unimolecular micelles and had excellent stability in aqueous solution. Moreover, the reduction-responsive feature of the micelles facilitated controlled release of drug, thus achieving targeted therapy and reduced toxicity to healthy cells. The in vitro cytotoxicity assays indicated that CPIO had a notable anticancer effect against HeLa and MCF-7 tumor cells. The confocal laser scanning microscopy and flow cytometry experiments revealed that CPIO micelles could be internalized into tumor cells efficiently. Furthermore, the obtained prodrug micelles produced better efficacy compared to free Ir. Moreover, the CPIO micelles showed excellent biocompatibility in vivo after intravenous injection on a mouse model. This study demonstrated that CPIO carrier could provide a rational design of a stimuli-responsive polymeric prodrug for delivery of irinotecan.
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PubMed
高影响因子
危险品化学品经营许可证（带存储）