JOURNAL OF POLYMERS AND THE ENVIRONMENT
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2025
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IF 5
Xie Shuangyu,Xie Yuhui,Lan Lugui,Wu Feng,Feng Dong,Meng Yang,Mei Yi,Xie Delong
In recent years, the development of bio-based flame retardants for flexible polyurethane foam (FPUF) has become essential, particularly due to environmental and health concerns associated with traditional petrochemical-derived additives. This study reports the successful synthesis of a novel bio-based flame retardant, NMDPLA, using renewable precursors: meglumine, phytic acid, and phenylboronic acid. NMDPLA was combined with protonated chitosan and ammonium polyphosphate through electrostatic self-assembly to create an intumescent flame retardant (APCS). The incorporation of NMDPLA and APCS notably enhances both mechanical properties and flame retardancy of FPUF. The formulation containing 40 wt% NMDPLA in total polyol and 3.0 wt% APCS achieved a Limiting Oxygen Index (LOI) of 23.6, showed no droplet formation in UL-94 tests, and produced a complete carbon residue. Cone calorimetry results demonstrated reductions in total heat release (THR) and peak heat release rate (PHRR) by 22.65% and 20.48%, respectively, compared to pure foam. Balancing mechanical performance and flame retardancy poses a significant challenge, as traditional additives often compromise one for the other. This work underscores the necessity of developing bio-based alternatives that effectively address this balance, enhancing fire safety while preserving material integrity and supporting the transition to sustainable solutions.
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Biology Direct
·
2025
·Vol. 20
·期 1
·1-15
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IF 4.9
Wei Xiaoyong,Zou Long,Huang Yanqing,Qiu Chuan,Cheng Guang,Chen Ye,Rao Jun
Background Hepatocellular carcinoma (HCC) is among the deadliest cancers globally. Yes-Associated Protein (YAP), a Hippo pathway effector, crucially regulates cell proliferation and apoptosis. Recent research has implicated YAP’s role in HCC progression, but the mechanisms are unclear. This study aims to clarify YAP’s function in HCC, emphasizing its regulation of key pathways and targets. Results Gene knockout and overexpression models were established in nude mice and cell lines of HCC cells to investigate YAP’s impact on tumorigenesis. Additionally, functional assays and molecular biology techniques were employed to identify YAP’s regulatory networks. The study demonstrates that LDHA-regulated lactate production promotes YAP activation and malignant phenotypes in HCC. Overexpression of LDHA in HepG2 and Huh7 cells increased lactate levels and activated the YAP pathway, enhancing cell proliferation, migration, and invasion. Lactate treatment also promoted these malignant phenotypes by inhibiting YAP phosphorylation at Ser127. In a xenograft model, lactate accelerated tumor growth through YAP activation. YAP lactylation at K102 antagonized its Ser127 phosphorylation, further promoting malignant progression. Conclusions This study highlights the significance of YAP in HCC pathogenesis, providing insights into potential therapeutic targets for HCC management. Graphical
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 7
·1-12
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IF 5.3
Guo Chunyan,Miao Pandeng,Yan Yifan,Li Xiaoqi,Du Shuaijing,Du Yingxiang
A capillary coating column was prepared for capillary electrochromatography (CEC) using a novel nanomaterial synthesized by chiral metal–organic frameworks (CMOFs) (Co 2 (L-Trp)(INT) 2 (H 2 O) 2 (ClO 4 ) and chiral molecularly imprinted polymers (CMIPs) as the stationary phase for enantioseparation of amlodipine. The rigid skeleton of CMOFs can be used as a support to reduce the deformation and collapse of CMIPs pores, the high specific surface area of CMOFs can increase the loading of molecular imprinting, while the viscosity of CMIPs improves the stability of stationary phases connected to the inner wall of capillaries. Compared with the capillary-coated columns with CMOFs and CMIPs as stationary phases alone, the novel capillary-coated columns utilizing the synergistic effect of CMIP@CMOF stationary phases showed a greatly improved chiral recognition (resolution: 0/0 → 5.79). The new nanomaterials synthesized by CMOFs and CMIPs as the stationary phase of CEC chiral resolution system show broad application prospects and potentials in the field of chiral drug/compound separation. Graphical
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 5
·1-12
·
IF 5.3
Zhai Tong,Shen Yu-Di,Yu Miao,Liu Jing-Min,Wang Shuo
Robust detection techniques combined with functional micro-/nano-entities can be an ideal solution for food-safety risk treatment related to aflatoxin B1 (AFB1). In this work, a porous covalent architecture-involved luminescent smart hydrogel with dynamic cross-linking and target-responsive framework was prepared for specific determination of AFB1 with remarkable sensitivity. Different from the existing hydrogel probe, the introduction of covalent organic frameworks (COFs) enhanced the hydrophobicity of hydrogel, enabling the selective capture of AFB1 with improved affinity while excluding large matrix molecules, thus creating an anti-interference detection environment. Additionally, the pH-responsive carbon dots (CDs) embedded in the smart hydrogel contributed to a dual signal amplification, induced by deconstruction of hydrogel to release the CDs and urease-catalyzed hydrolysis reaction to increase the pH, when the AFB1 presented. In view of this signal amplification and trace enrichment strategy, this smart hydrogel can achieve robust determination of AFB1 with a detection limit of 0.03 µM as well as good specificity. The method was validated using real-world samples, demonstrating excellent accuracy and precision compared to standard HPLC methods. This work not only advances the field of AFB1 detection but also provides a versatile and cost-effective platform that can be adapted for the detection of other toxins and biomolecules, addressing global food safety and environmental monitoring challenges. Graphical abstract
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Communications Materials
·
2025
·Vol. 6
·期 1
·1-9
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IF 9.6
Li Chenchen,Yang Zhenwei,Luo Xiaogang
While reducing current collector thickness improves battery energy density, further thinning commercial collectors compromises mechanical integrity and increases manufacturing costs. Here, we overcome these limitations by developing a lightweight (1.23 mg·cm -2 ), cost-effective cellulose composite membrane (CCM) via solution casting from an alkali/urea solvent. This CCM, composed of modified carbon nanotubes and natural cellulose, exhibits high electrochemical stability and flexibility, serving as both cathode and anode current collectors. CCM-containing batteries show 99.40% capacity retention after 500 cycles at 3 C. Replacing commercial collectors with CCM reduced their battery proportion to 6.23% and increased gravimetric energy density by 41.32%, while also reducing current collector costs by 50.36%. The CCM, produced through regenerated cellulose technology, is suitable for industrial-scale production, offering a strategy to enhance battery energy density with lightweight, low-cost current collectors.
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CHINESE JOURNAL OF POLYMER SCIENCE
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2025
·
IF 4
Xu Nan,Qiu Guo-Fang,Jin Li-Ping,Ji Chen-Peng,Gu Cong-Ke,He Ling-Xin,Guo Wen-Wen
In this study, a novel CS@SA@ZIF-67 core-shell nano-hybrid was synthesized using zeolitic imidazole framework-67 (ZIF-67) as a template and CS@SA@ZIF-67 as a modifier. Then, flame-retardant nanocomposites (EP/CS@SA@ZIF-67) were obtained by combining the hybrid with epoxy resins. The microstructure and morphology of CS@SA@ZIF-67 and the residual chars were explored using Fourier transform infrared (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD), and the effect of the obtained hybrid materials on the fire performance of the epoxy resins was characterized. Compared with the flame retardant system composed of ZIF-67 and pure EP, the hybrid flame retardant composites exhibited low total heat release and smoke production. The thermogravimetric analysis (TGA) results showed that the maximum thermal decomposition temperature of the EP/CS@SA@ZIF-67 based composite coating was stabilized at the highest value (378.2 and 563.9 °C) so that the introduction of CS@SA@ZIF-67 could improve the thermal properties of the EP/CS@SA@ZIF-67 composites to a certain extent. Meanwhile, the cone test results indicated that the peak heat release rate pHRR of the CS@SA@ZIF-67 filled EP composite was reduced by 18.43% compared to that of pure EP, implying enhanced flame retardancy. The enhanced thermal stability and flame retardancy of the CS@SA@ZIF-67 composites were mainly ascribed to the catalytic effect and carbonization ability of CS@SA@ZIF-67.
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Journal of the Korean Ceramic Society
·
2024
·
IF 2.7
Wang Zikang,Qian Miao,Shao Geyu,Xu Yuzhen,Song Qi
In this study, spark plasma sintering technology was used for fabricating B 4 C composite ceramics that contained 30 wt% (TiB 2 + SiC) by altering the sintering pressures (0 MPa, 50 MPa, and 80 MPa) at a comparatively low temperature of 1650 °C. This study showed how sintering pressure affected the densification behavior, microstructures, and mechanical characteristics of composite ceramics. Elevating the sintering pressure led to the inhibition of grain growth during the sintering process, ultimately resulting in the refinement of grains within the composite ceramics. At the same time, the quantity of internal pores in the composite ceramics was reduced, and the relative densities increased, so the flexural strength and hardness of the composite ceramics could be effectively improved. The quantity of microcracks and large aspect ratio second phase particles decreased with an increase in sintering pressure, which adversely affected the fracture resistance characteristics of the composite ceramics. In addition, the growth of B 4 C grains was hindered by TiB 2 and SiC generated by in-situ reactions, thus improving the mechanical characteristics of the composite ceramics. Comprehensive analysis showed that the composite ceramics had the best comprehensive mechanical properties when the sintering pressure was 80 MPa, displaying a relative density of 98.65%, a Vickers hardness of 30.71 GPa, a flexural strength of 531.19 MPa, and a fracture toughness of 5.78 MPa m 1/2 .
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2025
·Vol. 36
·期 8
·1-10
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IF 2.8
Tu Chuanbin,Xu Guojun,Chen Jun,Jin Chenxin,Gong Haojun,Liu Ji,Sun Fugen,Li Yong,Zhou Lang,Yue Zhihao
In this paper, copper (Cu) nanoparticles is deposited on the surface of silicon (Si) particles by electroless deposition. Then the electrode is prepared by mixing the modified Si/C particles with conductive agents and adhesives. Finally, rapid thermal process (RTP) is used to treat the electrode, so that interfacial Cu–Si alloyed and uniform carbon-coated Si anode materials (Si/Cu 3 Si/Cu@C) are obtained by one step. The reversible specific capacity remains 1362 mAh g −1 after 100 cycles at 0.2 C (1 C = 4.2 A g −1 ), which is 997 mAh g −1 higher than that of Si electrode. Through the multiplier test, the specific capacity of Si/Cu 3 Si/Cu@C holds on 604 mAh g −1 at 2 C. The excellent electrochemical performance of Si/Cu 3 Si/Cu@C composite materials is mainly attributed to the dual buffering media of nano-copper particles and carbon layers. Firstly, the presence of copper particles on the silicon surface can improve the overall conductivity and the volume expansion coefficient of silicon, thereby overcoming the rapid capacity decay of the electrode caused by excessive resistance. Secondly, the surface carbon layer can further alleviate the mechanical stress during the lithium intercalation and deintercalation process, effectively isolate the active material from the current collector, and ensure good electrical contact of the active particles and the stability of the surface SEI film.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
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IF 15.7
Chu Juan,Liu Zhaoli,Yu Jie,Wang Heng-Guo,Cui Fengchao,Zhu Guangshan
Two-dimensional conjugated metal organic frameworks (2D c-MOFs) hold significant promise as electrode materials for alkali metal ion batteries while their electrochemical properties still lack reasonable and effective regulation. Here, two representative 2D c-MOFs (M-HHTQ/M-HHTP, M=Cu or Ni) as positive electrodes are used as models to explore the basic/microscopic principles of their complex storage mechanism in sodium ion batteries (SIBs). It is demonstrated that the energy storage mechanism of 2D c-MOFs is determined by the interaction between coordination covalent bonds and organic linkers. Theoretical calculations and experiment results have jointly demonstrated that the redox potential and theoretical capacity can be regulated based on the valence of M-O bond and the utilization of anions and cations, respectively. As a result, Cu-HHTQ achieves a high discharge voltage at 2.55 V (vs. Na + /Na), a higher stable specific capacity of 208 mAh g −1 at 0.05 A g −1 , and long cyclability with the capacity retention rate of 100% at 1 A g −1 after 2000 cycles.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-18
·
IF 15.7
Xue Bin,Xu Zhengyu,Li Lan,Guo Kaiqiang,Mi Jing,Wu Haipeng,Li Yiran,Xie Chunmei,Jin Jing,Xu Juan,Jiang Chunping,Gu Xiaosong,Qin Meng,Jiang Qing,Cao Yi,Wang Wei
Hydrogels are extensively utilized in stem cell-based tissue regeneration, providing a supportive environment that facilitates cell survival, differentiation, and integration with surrounding tissues. However, designing hydrogels for regenerating hard tissues like bone presents significant challenges. Here, we introduce macroporous hydrogels with spatiotemporally programmed mechanical properties for stem cell-driven bone regeneration. Using liquid-liquid phase separation and interfacial supramolecular self-assembly of protein fibres, the macroporous structure of hydrogels provide ample space to prevent contact inhibition during proliferation. The rigid protein fibre-coated pore shell provides sustained mechanical cues for guiding osteodifferentiation and protecting against mechanical loads. Temporally, the hydrogel exhibits tunable degradation rates that can synchronize with new tissue deposition to some extent. By integrating localized mechanical heterogeneity, macroporous structures, surface chemistry, and regenerative degradability, we demonstrate the efficacy of these stem cell-encapsulated hydrogels in rabbit and porcine models. This marks a substantial advancement in tailoring the mechanical properties of hydrogels for stem cell-assisted tissue regeneration.
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AUSTRALASIAN PLANT PATHOLOGY
·
2025
·
IF 1.1
Chen Jiajia,Huang Xiaoxiao,Peng Jinfeng,Chen Yuanyuan,Gafforov Yusufjon,Xing Yifan,Yu Jian
Globisporangium recalcitrans is an important phytopathogenic oomycete that causes soybean root rot. To develop a loop-mediated isothermal amplification (LAMP)-based system for rapid and specific detection of G. recalcitrans , four LAMP primers and two loop primers were designed with the Ribosomal DNA transcribed spacer 2 sequence (ITS2) as the target gene. The specificity and sensitivity of these primers were validated, and the system was also successfully applied to detect G. recalcitrans in soybean tissues after artificial inoculation and natural infection. The nucleic acid amplification reaction was performed under isothermal conditions at 63 °C for 60 min. Specificity was compared with those for 71 strains of G. recalcitrans , other Globisporangium spp. The minimum detection limit of the system was 100 fg·μL −1 for detecting fungal genomic DNA. This LAMP-based system provides a technique for specific detection of G. recalcitrans and rapid diagnosis of the disease it caused.
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IONICS
·
2025
·
IF 2.6
Qiao Jun,Zhang Jiawei,Geng Weiyao,Wang Shichao,Wei Feng
Coal tar pitch (CTP) is widely used in road laying. However, how to realize its high added value is still a difficult problem to be solved. Herein, we report the simple avenue for the synthesis of N doped porous carbon (NPC Mg ) by template method derived from aromatic hydrocarbons in CTP. The NPC Mg presents big surface area of 2523.2 m 2 g −1 and hierarchical pore structures, temperate N content of 1.88 at.%. Due to the structural merits, NPC Mg electrode obtains large capacitance of 483.1 F g −1 at 0.1 A g −1 and superb cycle stability with 4.6% decay after 25,000 cycles in 6 M KOH solution. Besides, NPC Mg -based supercapacitor with neutral electrolyte also achieves high capacitance of 339 F g −1 , large energy output of 33.3 Wh kg −1 , long cycle life without decay after 15,000 cycles. Interestingly, the NPC Mg -based zinc ion hybrid capacitor presents large capacity of 287.7 F g −1 and superb energy output of 114 Wh kg −1 . This work provides a common approach to synthesize heteroatom doped carbon materials for capacitors.
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