TALANTA
·
2026
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IF 6.7
Wenli Chen,Renjie Li,Wenxi Wang,Kaixi Yin,Xiandeng Hou,Li Wu
A facilely fabricated Ag/Cu-TCPP was developed as a SERS substrate. • Saliva uric acid (UA) was quantified with 0.04 μM detection limit. • Synergy in molecular enrichment and EM enhancement improved SERS sensitivity. • Time-resolved monitoring of UA fluctuations in real saliva samples was achieved. Surface-enhanced Raman scattering (SERS) methods offer high sensitivity for uric acid (UA) detection, but efficient molecular enrichment and reliable analysis in complex biological matrices remain challenging. Here, we developed an Ag/Cu-TCPP SERS platform for noninvasive determination of UA in saliva. The platform combined the electromagnetic enhancement provided by Ag nanoparticles (Ag NPs) with the molecular enrichment capability of Cu-TCPP. Density functional theory calculations further indicated that UA can be enriched on Cu-TCPP through weak Cu···O quasi-coordination between the UA carbonyl oxygen and exposed Cu centers, accompanied by interfacial charge redistribution. Consequently, the platform achieved a low detection limit of 0.04 μM and a wide linear range of 0.1–1000 μM. Beyond conventional single-point determination, the platform enabled time-resolved assessment of salivary UA concentration, revealing temporal fluctuations under physiological and feeding-related conditions. These results highlight the potential of MOF-integrated SERS platforms for noninvasive monitoring of small-molecule biomarkers. Download: Download high-res image (242KB) Download: Download full-size image
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高影响因子
JOURNAL OF MATERIALS SCIENCE
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2026
·Vol. 61
·期 44
·34779-34794
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IF 4.4
Wen Lihan,Shen Juan,Wu Shuangxian,Jin Bo
Radioactive strontium ( 90 Sr) contamination in water bodies poses one of the most persistent and serious threats to both ecological safety and public health, owing to its long half-life, high environmental mobility, and strong propensity for biological accumulation. However, a rapid and sustainable synthetic route for bimetallic MOF-74 with high Sr 2+ adsorption capacity remains lacking. This study reports a solvent‑free mechanochemical strategy for the synthesis of a bimetallic Cu/Zn-MOF-74 (CZ-M74-11) using a spiral gas-solid flow (S-GSF) method in just 1 min. The material achieves 98.26% Sr 2+ removal within 15 min and exhibits a maximum Langmuir adsorption capacity of 295.13 mg·g −1 at 303.15 K. Kinetic and thermodynamic analyses indicate that the adsorption is spontaneous and exothermic. XPS and FT-IR analyses, together with cyclic desorption data, reveal that Sr 2+ uptake proceeds primarily through outer-sphere complexation, with a minor contribution from inner‑sphere coordination involving carboxylate groups. This work addresses the gap in rapid and sustainable routes for bimetallic MOF-74 synthesis by introducing an S-GSF method that achieves excellent adsorption capacity and ultrafast kinetics for Sr 2+ removal. Graphical abstract
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Journal of Energy Chemistry
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2025
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IF 14.9
Meina Tan,Jingming Ge,Yang Qin,Jiaxin Luo,Yiping Wang,Fazhi Zhang,Xuhui Zhao,Xiaodong Lei
Aqueous hybrid-ion batteries (AHBs) are a promising class of energy storage devices characterized by low cost, high safety, and high energy density. However, aqueous Cu-Al hybrid-ion batteries face challenges such as sluggish reaction kinetics and severe structural collapse of cathode materials, which limit their practical application. Here, a high-performance aqueous Cu-Al hybrid-ion battery is developed using aluminum pre-inserted Cu 9 S 5 (Al-Cu 9 S 5 ) as the cathode material, derived from CuAl-layered double hydroxide (CuAl-LDH). The Al 3+ pre-intercalation strategy narrows the band gap, enhancing electron transport and improving electrochemical kinetics. The battery exhibits excellent rate performance (463 and 408 mA h g −1 at current densities of 500 and 1000 mA g −1 , respectively) and good cycle stability (with a capacity retention ratio of 81% after 300 cycles at a current density of 1000 mA g −1 ). Its performance surpasses that of most reported Al-ion batteries. Ex situ characterization and density functional theory (DFT) calculations reveal that the pre-intercalated Al 3+ in Al-Cu 9 S 5 participates in the reversible embedding/removal of Al ions during charge/ discharge processes. These findings provide valuable insights for designing pre-intercalated cathodes in aqueous Cu-Al hybrid-ion batteries with stable cycle life.
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高影响因子
Chemosensors
·
2025
·Vol. 13
·期 6
·200
·
IF 3.7
Xuanlin Feng,Jiaqi Zhao,Shiwei Wu,Ying Kan,Honemei Li,Weifei Zhang
Hydroxychloroquine (HCQ), a cornerstone therapeutic agent for autoimmune diseases, requires precise serum concentration monitoring due to its narrow therapeutic window. Current HCQ monitoring methods such as HPLC and LC-MS/MS are sensitive but costly and complex. While electrochemical sensors offer rapid, cost-effective detection, their large chambers and high sample consumption hinder point-of-care use. To address these challenges, we developed a microfluidic electrochemical sensing platform based on a screen-printed carbon electrode (SPCE) modified with a hierarchical nanocomposite of gold nanoparticles (AuNPs), copper-based metal–organic frameworks (Cu-MOFs), and multi-walled carbon nanotubes (MWCNTs). The Cu-MOF provided high porosity and analyte enrichment, MWCNTs established a 3D conductive network to enhance electron transfer, and AuNPs further optimized catalytic activity through localized plasmonic effects. Structural characterization (SEM, XRD, FT-IR) confirmed the successful integration of these components via π-π stacking and metal–carboxylate coordination. Electrochemical analyses (CV, EIS, DPV) revealed exceptional performance, with a wide linear range (0.05–50 μM), a low detection limit (19 nM, S/N = 3), and a rapid response time (<5 min). The sensor exhibited outstanding selectivity against common interferents, high reproducibility (RSD = 3.15%), and long-term stability (98% signal retention after 15 days). By integrating the nanocomposite-modified SPCE into a microfluidic chip, we achieved accurate HCQ detection in 50 μL of serum, with recovery rates of 95.0–103.0%, meeting FDA validation criteria. This portable platform combines the synergistic advantages of nanomaterials with microfluidic miniaturization, offering a robust and practical tool for real-time therapeutic drug monitoring in clinical settings.
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高影响因子
ELECTROCHIMICA ACTA
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2025
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IF 5.6
Haoqi Liang,Yutong Yang,Yijia Wang,Zejun Deng
Escalating aquatic contamination by toxic heavy metal ions (HMIs) urgently requires field-deployable electrochemical sensors surpassing traditional methods. This work proposed a controllable synthesis of cobalt-embedded nitrogen-doped carbon/carboxyl-functionalized multi-walled carbon nanotube (Co@NC/CMWCNTs) composites through in situ growth of ZIF-67 on CMWCNTs, followed by optimized carbonization. CMWCNTs-directed morphological evolution was systematically demonstrated, revealing that with increasing CMWCNT ratios, the ZIF-67 crystallite size underwent an initial increase and later decay, and after carbonization, a unique knot-like interpenetrating architecture was formed with CMWCNTs as bridges and Co@NC as nodes. This synergistic structure significantly enhanced electrical conductivity and electrocatalytic activity, as evidenced by electrochemical characterization. Compared to the glassy carbon electrode (GCE), the Co@NC/CMWCNTs/GCE sensor exhibited a 12-fold reduction in charge transfer resistance (28.3 Ω vs. 346.8 Ω), a 21% larger electroactive surface area, and rapid heterogeneous electron transfer kinetics of 3.8 × 10⁻³ cm s -1 . The composite sensor allowed simultaneous detection of Cd²⁺, Pb²⁺, Cu²⁺, and Hg²⁺ in 0.1 M NaAc-HAc buffer (pH 4.5) with high sensitivities (169.7, 199.0, 135.9 and 108.0 μA·μM⁻¹ cm -2 ), low detection limits (40.0, 40.5, 87.5 and 106.2 nM) and observed cross-interference within 10%. This work establishes a materials design paradigm for MOF-derived electrochemical sensors for low-cost on-site environmental monitoring of HMIs.
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高影响因子
Biomaterials Advances
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2025
·
IF 6
Gao Pan,Qi Zhong,Tiange Wang,Xiuwen Gao,Huixing Li,Jiajun Li,Hui Yang,Cijun Shuai,Shuping Peng
Molybdenum disulfide (MoS 2 ), a typical piezoelectric sonosensitive material, holds great promise in ultrasound-activated catalytic antibacterial applications and osteogenic differentiation promotion. However, it has two key limitations: rapid carrier recombination leading to insufficient antibacterial activity; and difficulty in forming stable interfaces with biopolymers as an inorganic compound, which impairs effective sonocurrent transmission in heterojunction scaffolds for osteogenesis induction. To address these issues, we proposed a multi-beneficial strategy: anchoring Cu-MOF to MoS 2 via Cu S chemical bonds to construct a Type-II MoS 2 /Cu-MOF heterojunction. Under ultrasonic stimulation, this heterojunction undergoes polarization to form a built-in electric field, accelerating carrier separation and enhancing catalytic efficiency. Additionally, Cu-MOF releases Cu + and Cu 2+ ions, which undergo Fenton-like reactions with bacterial endogenous H 2 O 2 and glutathione to generate hydroxyl radicals via chemodynamic effects, increasing reactive oxygen species (ROS) production; the resultant oxygen further boosts sonodynamic efficiency. Furthermore, Cu 2+ in MoS 2 /Cu-MOF forms metal coordination bonds with carboxyl groups in poly-l-lactic acid (PLLA) macromolecules, constructing an interfacial “Line-Point-Plane” ternary structure that enhances interfacial electron transfer efficiency, facilitates sonocurrent transmission, and thus effectively realizes electrical stimulation for osteogenic differentiation. Specifically, we incorporated the heterojunction into PLLA matrix powder and fabricated MoS 2 /Cu-MOF/PLLA heterojunction scaffolds via selective laser sintering (SLS). Under ultrasonic stimulation, these scaffolds achieve synergistic sono/chemodynamic antibacterial activity, while ultrasound-activated sonocurrents transmit through the ternary interfacial structure of the heterojunction scaffolds to effectively induce osteogenic differentiation. Results showed that compared to pure MoS 2 scaffolds, the heterojunction scaffold exhibited a 0.4 eV narrower band gap and a 350 Ω lower impedance, with antibacterial rates of 97.3 % and 98 % against Staphylococcus ( S.aureus ) and Escherichia coli ( E.coli ), respectively. Notably, under ultrasonic irradiation, the upregulation of osteogenic factors such as Wnt-10b is induced, and osteoblast differentiation is promoted simultaneously; the results indicate that osteogenic factors like Wnt-10b have a potential role in promoting osteoblast differentiation under ultrasonic conditions.
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PubMed
高影响因子
ACS Applied Optical Materials
·
2026
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IF 3.4
Shichao Rao,Wentao Niu,Zhongwei Man,Xiulin Xie,Zhe Yin,Yue Qin,Shuaibing Wang,Ouyang Lin,Aiwei Tang
The advancement of environmentally benign I–III–VI colloidal quantum dots (QDs) has established a promising materials platform to replace cadmium-based counterparts. However, in practical device architectures, especially blue-emitting devices, abundant surface nonradiative recombination centers and imbalanced carrier injection often lead to suboptimal device performance, thereby hindering their deployment in display technologies. Herein, we employ a zinc iodide (ZnI2) post-treatment for the Cu–Ga–Zn–S (CGZS) QDs film strategy, effectively passivating surface defects and nonradiative sites, thereby enhancing device performance. The treated QDs facilitate the formation of an interface dipole, which effectively elevates the overall energy levels of the QDs while simultaneously reducing the hole injection barrier, leading to an enhanced hole injection efficiency. Working in concert, these effects facilitate balanced carrier injection and optimize exciton recombination, thereby boosting the device efficiency and operational stability. Consequently, the peak external quantum efficiency (EQE) exhibits a favorable improvement, increasing from 1.01% in the pristine device to 1.90% after treatment. This work offers an effective approach to achieving balanced carrier injection in quantum-dot light-emitting diodes (QLEDs) and establishes a solid foundation for the development of high-performance, cadmium-free, blue-emitting QLEDs.
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高影响因子
ACS Catalysis
·
2026
·
IF 13.6
Qiliang Liu,Wenxing Yang
Recently, an intense Raman peak at approximately 520–544 cm–1 (briefly named as *530 in this study) has been widely observed and discussed during in situ spectroscopic studies of electrochemical CO2 or CO reduction reaction (CO(2)RR). Several mechanisms were proposed to explain the nature of this peak, most notably attributing it to Cu–OHad or CuOx(OH)y, which was then utilized as a key spectroscopic indicator in various mechanistic discussions. Herein, by systematic isotopic-labeled spectroscopic studies, we show that the nature of the *530 peak may not be the previously proposed species, but more likely a surface species containing (C, O) in equilibrium with inert bridging-type adsorbed CO (*CObridge). Both the formation of *530 and *CObridge is shown to be associated with the spontaneous reconstruction of Cu. The *CObridge and *530 Raman modes share the same adsorption sites and can interconvert into each other via the variation of electrochemical potentials. Finally, the appearance of both peaks is shown to signalize a deteriorated C2+ products performance of CO2RR and CORR. These results update the current understandings of the role of *530 for CO(2)RR. It also highlights that the emerging-recognized electrocatalyst reconstruction phenomenon can be accompanied by the formation of diverse surface adsorbates, casting challenges, and necessitating rigorous spectroscopic studies for better mechanistic understanding.
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高影响因子
JOURNAL OF LIGHTWAVE TECHNOLOGY
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2026
·
IF 5.2
Zhiyong Yin
The simultaneous and specific detection of multiple heavy metal ions in complex environments remains a significant challenge for optical fiber sensors, primarily due to spectral crosstalk and temperature interference. To address this, we present a monolithically-integrated, dual-channel surface plasmon resonance (SPR) fiber sensor capable of crosstalk-compensated and temperature-compensated detection of Cu²⁺ and Ni²⁺. The sensor is fabricated by cascading two sensing regions on a single microstructured optical fiber (MOF), where a strategic combination of heterogeneous metallic films—a silver film for the Cu²⁺ channel and a gold film for the Ni²⁺ channel—creates two spectrally distinct resonance dips in the visible range. To overcome the limitation of specificity, ion-imprinted polymers (polyacrylic acid and chitosan) are functionalized onto the respective channels, creating highly selective recognition sites. Furthermore, an independent temperature-sensing probe, with its resonance strategically located in the near-infrared region, is incorporated into the optical path for real-time temperature monitoring, effectively eliminating thermal cross-sensitivity. Experimental results demonstrate that the sensor exhibits high sensitivity (up to 0.41 nm/μM for Cu²⁺ and 0.34 nm/μM for Ni²⁺ in the low concentration regime), a fast response time (20-30 s), and low detection limits. This work provides a compact and robust all-in-one sensing solution that paves the way for practical, multi-analyte environmental monitoring.
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高影响因子
Energy & Environmental Materials
·
2026
·
IF 13.8
Xiaozhe Song,Cong Yan,Qinghua Yan,Congzhe Ren,Xin Liu,Ruiyan Zhang,Lei Chen,Chongqing Xu,Zhouyang Long,Wenyu Wang,Mingming Song,Xiaoguo Shi,Hui Wang
Photocatalytic processes driven by visible-light irradiation offer a sustainable means of micropollutants removal from aquatic environments without the addition of reagents. In this study, an enhanced production of photogenerated carriers under visible light has been achieved using acidified graphitic carbon nitride (ag-C 3 N 4 ) modified with atomically dispersed Cu (Cu/ag-C 3 N 4 ), which serves as an efficient photocatalyst for treating antibiotic micropollutants. The optimized Cu/ag-C 3 N 4 system achieved >90% micropollutants removal efficiency within 30 min. A combination of experimental testing and density functional theory analysis has confirmed the formation of an active and stable CuN 3 configuration, generated by the incorporation of atomic Cu species at C vacancies that effectively modulates surface charge redistribution and enables charge separation. The photocatalytic degradation of micropollutants is promoted by photogenerated holes (h + ) in tandem with reactive oxygen species ( · OH $$ \cdotp \mathrm{OH} $$ , O 2 − · $$ {\mathbf{O}}_2^{-}\cdotp $$ , 1 O 2 ), where O 2 − · $$ {\mathrm{O}}_2^{-}\cdotp $$ and 1 O 2 species play dominant roles in the Cu/ag-C 3 N 4 system. The application of ultra-performance liquid chromatography–tandem mass spectrometry analysis has been used to identify possible degradation pathways and establish a synergistic degradation mechanism. This work provides a comprehensive understanding of heteroatom doping that enhances photocatalytic activity, offering a new strategy in designing highly efficient photocatalysts for treating micropolluted water.
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高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2026
·
IF 4.7
Wang Rong,Ma Yirong,Li Wenlin,Zhang Xin,Cheng Jiale,Bai Hao,Zheng Jiajun,Yu Feng,Fan Binbin,Li Ruifeng
Cu/zeolite catalysts have attracted considerable attention for cold-start applications; however, their efficiency in propylene adsorption remains limited. To address this challenge, Cu/ZSM-5 catalysts with enhanced metal-support interactions were successfully constructed via a seed-assisted, template-mediated synthesis method, leading to improved propylene capture and oxidation efficiency. The catalysts were systematically characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR), N 2 adsorption-desorption, scanning electron microscope (SEM), transmission electron microscope (TEM), NH 3 -TPD, X-ray photoelectron spectroscope (XPS), and in situ infrared spectroscopy to investigate the influence of acid site density and metal-support interactions on propylene adsorption behavior. The results demonstrated that Cu@ZSM-5 catalysts synthesized with different structure-directing agents exhibited distinct acidity profiles and varying strengths of metal-support interaction. Among them, the Cu@ZSM-5-130 sample prepared using the TPAOH template showed a high specific surface area (474 m 2 /g) and a more optimal acidity balance. It was found that an excessive density of strong acid sites can be detrimental to propylene adsorption and oxidation. The intimately associated Cu species within the zeolite matrix facilitated selective adsorption of hydrocarbons, particularly propylene. In situ infrared spectroscopy further revealed a temperature-dependent oxidation pathway of propylene over the Cu@ZSM-5-TPAOH-130 catalyst, starting with epoxide formation at low temperatures, progressing to partial oxidation products ( e.g. , acrolein) at intermediate temperatures, and ultimately yielding complete oxidation products, such as CO 2 and H 2 O at higher temperatures. The alternative text for this image may have been generated using AI.
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高影响因子
ACS Catalysis
·
2026
·
IF 13.6
Kaixuan Chen,Xintian Luo,Hansheng Wang,Shangzhi Xie,Huibing He,Jing Xu
Low ethylene glycol (EG) selectivity and insufficient stability in the complex multistep hydrogenation of dimethyl oxalate (DMO) have invariably stimulated a research focus of copper-based catalysts. Conventional catalyst development heavily relies on extensive trial-and-error experimentation and serendipitous discovery. In order to efficiently predict high-performance catalysts, this study constructs a machine learning (ML) model based on the K-means clustering algorithm to successfully screen out the potential Ga promoter. Experimental results demonstrate that a 0.5Ga-Cu/SiO2 catalyst achieves nearly 100% DMO conversion and 98.59% EG selectivity at a relatively low temperature (180 °C) and high weight hourly space velocity (1.5 h−1), while maintaining continuous operational stability for over 240 h. Physical characterizations reveal that Ga2O3 promotes the dispersion of copper species and reduces local electron density, thereby modulating the balance between Cu0 and Cu+ dual active sites. Moreover, density functional theory calculations indicate that the interfacial interaction between Ga2O3 and copper species enhances the substrate dissociation adsorption. This study validates the utility of ML in screening advanced copper-based catalysts for efficient DMO hydrogenation to EG and provides a valuable framework for the future catalyst design in the thermocatalytic field.
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