DESALINATION
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2022
·
IF 11.211
Huiting Xu,Meng Li,Siqi Gong,Fan Zhao,Yuexin Yan,Chunli Li,Junjie Qi,Zhiying Wang,Yuqi Hu,Honghai Wang,Xiaobin Fan,Wenchao Peng,Jiapeng Liu
Various large specific surface area carbon-based materials have been considered as fascinating electrode materials for capacitive deionization . However, the low adsorption capacity and sluggish desalination rates of traditional carbon-based materials still impede the further development of capacitive deionization. Herein, we successfully synthesized the nitrogen and fluorine co-doped porous carbon nanosheets (N, F@CNs) with abundant edge-defects via a facile one-pot strategy and systematically investigated its electrochemical properties for capacitive deionization. The introduction of F heteroatom not only effectively improves the edge-defect density and increases the adsorption sites, but also accelerates the ions and electrons transport, which can significantly enhance the electrochemical performance of the N, F@CNs. As a result, in an asymmetric CDI device, the N, F@CNs delivered an excellent salt (Na + ) adsorption capacity (71 mg g −1 ) at the applied potential of 1.2 V, which significantly higher than that of N-doped carbon nanosheets (32 mg g −1 ), along with outstanding cycling stability. Furthermore, the adsorption/desorption mechanisms involved were detailedly elucidated via systematic characterizations. Therefore, this work provides a new thought for designing carbon-based materials with excellent performance for capacitive deionization.
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高影响因子
Food Packaging and Shelf Life
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2022
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IF 8.749
Dongxiu Qi,Yewen Xiao,Li Xia,Linlin Li,Suwei Jiang,Shaotong Jiang,Hualin Wang
Colorimetric films are emerging as a facile and effective indicator for freshness monitoring. To meet the versatile demands of consumers, multifunctionality is desirable for the colorimetric films. Here, an antibacterial-antioxidant colorimetric film was developed by incorporating nisin and anthocyanins of pomegranate/ Clitoria ternatea (PGA/CTA) into ethylene vinyl alcohol (EVOH) matrix. The precursor of EVOH/nisin 10 was determined for the incorporation of PGA/CTA of 1:2. The pH-sensing nature and antioxidant activity were originated from the mixture of PGA/CTA, while the antibacterial activity was from nisin. The components of and PGA/CTA in the matrix were well-dispersed and hydrogen-bonded. The color changes of the target film of EVOH/nisin-(PGA/CTA) 3 were distinguishable at pH 2–12 and film was sensitive to the pH-stimuli of volatile ammonia and acetic acid. In addition, the film exhibited good antioxidant activity (DPPH·scavenging activity of ~80 %) and antibacterial activity against S. aureus (approximating bactericidal effectiveness). The film can not only monitor shrimp freshness effectively but extend the shelf-life of the packaged shrimp by 100 % at storage of 4 °C, revealing its potential in active intelligent food packaging. The combination of two different sourced anthocyanins along with nisin provides a strategy for achieving an efficacy of freshness retaining plus monitoring.
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CARBOHYDRATE POLYMERS
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2022
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IF 10.723
Dan Gao,Sajid Asghar,Junxiu Ye,Mei Zhang,Rongfeng Hu,Yadong Wang,Lin Huang,Chengjun Yuan,Zhipeng Chen,Yanyu Xiao
In this study, a CD44 and biotin receptors dual-targeted enzyme-sensitive hyaluronic acid nanogel loading paclitaxel (PTX/Bio-NG) for targeting breast cancer was constructed. Spherical nanogels with a mean particle size of 149.1 ± 1.6 nm, higher entrapment efficiency (90.17 ± 0.52 %) and drug loading (15.28 ± 0.10 %) were obtained. PTX/Bio-NG quickly released drugs under the catalysis of hyaluronidase and/or lipase . Cell studies revealed that the uptake of Bio-NG by 4T1 cells was mediated by CD44 receptor and Bio-specific receptor. Compared with PTX-loaded biotin-free NG (PTX/NG), PTX/Bio-NG had higher cytotoxicity against breast cancer cells (4T1 cells). The rats pharmacokinetic profile indicated higher AUC 0-t but lower clearance rates of PTX/NG (6.24 times and 15.96 %, respectively) and PTX/Bio-NG (6.66 times and 14.89 %, respectively) than control group (Taxol). In vivo studies showed that PTX/Bio-NG possessed excellent therapeutic efficacy in 4T1 tumor-bearing Balb/c mice, which suggest that PTX/Bio-NG could be an excellent candidate for the treatment of breast cancer.
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PubMed
高影响因子
Chemical Biology & Drug Design
·
2022
·Vol. 100
·期 3
·305-312
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IF 2.873
Shiyang Zhou,Xiaofeng Zhou,Gangliang Huang
In order to explore the potential anti-tumor activity functional molecules, a series of Fissitungfine B derivatives were designed and synthesized. Their anti-tumor activity effects on Hela, MCF-7 and A-549 cell lines were evaluated in vitro. The results showed that some of these Fissitungfine B derivatives exhibited moderate to good anti-tumor activities. Especially, compound 4 g with the highest inhibitory activities against all tested cell lines with the Hela was IC 50 = 3.82 ± 0.56 μM, MCF-7 was IC 50 = 5.53 ± 0.68 μM, and A-549 was IC 50 = 4.55 ± 0.53 μM. Furthermore, the compounds 4 g have higher inhibitory effects on TDP2 in vitro . In vivo, the biological activities assay results showed that the target compound 4 g had a good inhibitory effect on tumor growth . The target compound 4 g could inhibit tumor growth well, which might be use as a candidate drug or lead compound for further research and development anti-tumor agents.
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PubMed
高影响因子
RSC Advances
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2022
·Vol. 12
·期 36
·23437-23446
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IF 4.036
Lina Wang,Qi Wu,Ru Yu,Hongge Zhang,Fei Nie,Wenyan Zhang
A silver nanoparticle-doped Zn(II) metal–organic framework composite (AgNPs@ZnMOF) was investigated as an electrochemiluminescence (ECL) signal enhancer for potassium persulfate. First, ZnMOF was prepared by a one-step hydrothermal method, and then AgNPs@ZnMOF composite was obtained by depositing AgNPs on the surface and interior of ZnMOF. After the AgNPs@ZnMOF composite was modified on the glass carbon electrode (GCE), the cathode luminescence of potassium persulfate on bare GCE was enhanced by 8 times. A dual amplification mechanism provided by Zn(II) and Ag nanoparticles in the AgNPs@ZnMOF composite has been validated by ECL spectra, fluorescence spectra, and electrochemical methods. The interaction between the sulfhydryl groups in L-cysteine (L-Cys) and AgNPs significantly affects the catalytic luminescence of the AgNPs@ZnMOF composite. Thus, a sensitive ECL method for the determination of L-Cys was developed based on the inhibition effect of L-Cys on the ECL signal within the linear range from 5.0 nM to 1.0 μM and the limit of detection was found to be 2 nM (S/N = 3). The established method has been successfully applied to the determination of L-Cys in human urine.
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PubMed
高影响因子
Molecular Catalysis
·
2022
·
IF 5.089
Weizuo Li,Jing Wang,Dafang He,Guangyu He,Haiqun Chen
Developing highly efficient MOFs derived alloy catalysts for the one-pot tandem catalytic reactions remains a challenge. In this work, a novel solid-solution confined NiCo alloy catalyst incorporating carbon (termed as NiCo/MgO-C) with banana-like morphology has been synthesized via a self-templating strategy for directing pyrolysis of well-defined Ni-Co-Mg tri-metallic MOFs (termed as Ni-Co-Mg@H 2 dhbdc, H 2 dhbdc represents 2,5-dihydroxytelephthalic acid organic linker). The developed NiCo/MgO-C catalyst was applied for the hydrogenation-alkylation tandem catalytic reaction. Owing to the unique structural (e.g., highly dispersed, small size of NiCo nanoparticles, enhanced transfer of electron density) as well as NiCo alloy advantages, the developed NiCo/MgO-C catalyst derived from Ni-Co-Mg@H 2 dhbdc MOFs delivers excellent superior catalytic performance for the hydrogenation-alkylation tandem reaction to those of bimetallic MOFs (Ni-Mg@H 2 dhbdc and Co-Mg@H 2 dhbdc, respectively) derived catalysts (Ni/MgO-C and Co/MgO-C, respectively). Notably, the tri-metallic Ni-Co-Mg@H 2 dhbdc served as the precursor for synthesis of developed catalyst could enhance the reduction degree of NiO/CoO species confined in NiO CoO-MgO solid-solution during the pyrolysis process to some extent. Therefore, we anticipated that this tri-metallic MOFs-templated strategy may provide a facile and controllable way for synthesis of solid-solution supported nanoalloy catalysts for the other heterogeneous catalytic reactions.
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MATERIALS & DESIGN
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2022
·
IF 9.417
Lingling Pan,Dawei Jiang,Luqi Pan,Zhizhen Meng,Yangyang Zhuang,Yueyue Huang,Fanrong Ye,Changcan Shi,Jie Chen,Jingye Pan
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection and causes high ratios of morbidity and mortality worldwide. Although many potential therapeutic targets have been reported, the therapeutic effect needs to be further improved. Herein, we report a strategy to specifically target inflammation site via anti-ICAM-1 antibody bonded antibacterial peptides polymeric nanoparticle. Antibacterial peptide (KR-12) grafted amphipathic PCL- b -P(OEGMA- co -AMA)- g -Cys-KR-12 block copolymer and PCL- b -P(OEGMA- co -AMA)- g -biotin block copolymer were synthesized by ring-opening polymerization and click chemistry. Then, antibacterial peptides polymeric nanoparticles (AMPNP) were prepared by co-assembly of amphipathic PCL- b -P(OEGMA- co -AMA)- g -Cys-KR-12 and PCL- b -P(OEGMA- co -AMA)- g -biotin in aqueous solution. Intercellular adhesion molecule-1 (ICAM-1) is highly expressed on the surface of inflammatory endothelial cells, and the anti-ICAM-1 antibody can specifically bind to it. To obtain the anti-ICAM-1-AMPNP nanoparticles, biotinylated anti-ICAM-1 antibodies were bonded on the surface of AMPNP nanoparticles through the biotin-avidin system. The anti-ICAM-1-AMPNP nanoparticles had low systemic toxicity and exhibited ideal antibacterial property against drug-resistant bacteria, Gram-negative bacteria and Gram-positive bacteria. The anti-ICAM-1-AMPNP nanoparticles exhibited favorable targeting capabilities to inflammation endothelial cells in vitro and significantly reduced the inflammatory response of CLP mice in vivo . The present investigation might provide a specific strategy for targeting combating sepsis with anti-ICAM-1-AMPNP nanoparticles.
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Molecular Catalysis
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2022
·
IF 5.089
Tao Chen,Dongxin Pan,Jie Zhu,Menglin Xie,Ting Li,Yu Zhou,Jun Wang
Direct benzene hydroxylation with dioxygen (O 2 ) is among the most promising alternative pathways for green phenol production, but efficient catalysis systems usually involve metal species or other additives such as sacrificial agents. In this work, we designed a carbon catalyst from the hydrothermal treatment of biomass-derived sucrose and constructed a metal-/additive free heterogeneous catalytic system for benzene hydroxylation to phenol with O 2 . The champion carbon sample gave a high phenol yield of 13.4%. The catalyst was facilely recovered and reused without apparent deactivation. There abundant oxygen functional groups such as phenolic and quinone carbonyl groups served as the active sites and polyfuran units accelerated the O 2 adsorption and activation. The synergistic effect of these surficial organic groups is conducive to the formation of reactive oxygen species, hydroxyl radicals, which effectively oxidized the benzene to phenol.
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APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Chenghao Zhang,Chun Li,Zongjing He,Dejun Gao,Junlei Qi,Jian Cao
Multi-level hierarchical surface roughness is the key to natural superhydrophobic materials. In this work, rough surfaces of a novel superhydrophobic material are achieved by the reactive wetting technique. The molten AgCuTi alloy is applied to infiltrate into the porous anodic aluminum oxide (AAO) membrane, and wetting of molten AgCuTi is promoted by the reaction layer formed at the interface between AAO and AgCuTi. The AgCuTi infiltrates the AAO nanopores and forms the first-level surface roughness based on reactive wetting. To release the nanostructures embedded in the AAO pores, hydrothermal etching with NaOH aqueous solution was used to remove AAO. Meanwhile, TiO 2 nanostructures are synthesized under hydrothermal conditions, resulting in the second-level surface roughness. After modification, the surface is found to exhibit excellent superhydrophobic properties, including a high water contact angle (WCA) and low roll-off angle (RA). The superhydrophobic surface also shows self-cleaning, mechanical durability and long-term stability. The as-prepared surface exhibits excellent repellence for water solutions with different pH values. This method could be applied to fabricate superhydrophobic surfaces on different kinds of materials, showing broad application prospects.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 36
·17223-17234
·
IF 3.925
Dajie Zhang,Jiabao Sun,Qiang Li,Haocheng Song,Dongsheng Xia
Biochar emerged as a promising material due to its high efficiency and tunable physicochemical properties. In order to improve the economic applicability of biochar catalysts, we attempted to apply formed Cu-doped deactivated magnetic loofah biochar (Cu-Fe-LBC) as a peroxymonosulfate (PMS) activator to remove tetracycline (TC). The catalyst exhibited high activation of PMS and high stability with the TC removal of 97.6%. The chemical composition and groups on the catalyst surface confirmed the presence of copper ions on the biochar by complexation with COO–. Analysis of quenching experiments and electron paramagnetic resonance indicated the significance of HO˙ and 1O2 in TC degradation. The catalytic system had high catalytic efficiency with a wide pH range and coexisting anions. The possible degradation mechanism was proposed. Moreover, the research provides an insight into the PMS activation by reusing waste biochar catalysts.
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Materials Today Bio
·
2022
·
IF 10.761
Bingyang Lu,Xiao Han,Dan Zou,Xiao Luo,Li Liu,Jingyue Wang,Manfred F. Maitz,Ping Yang,Nan Huang,Ansha Zhao
Chronic wounds and the accompanying inflammation are ongoing challenges in clinical treatment. They are usually accompanied by low pH and high oxidative stress environments, limiting cell growth and proliferation. Ordinary medical gauze has limited therapeutic effects on chronic wounds, and there is active research to develop new wound dressings. The chitosan hydrogel could be widely used in biomedical science with great biocompatibility, but the low mechanical properties limit its development. This work uses polyacrylamide to prepare double-network (DN) hydrogels based on bioadhesive catechol-chitosan hydrogels. Cystamine and N, N′-Bis(acryloyl)cystamine, which can be cross-linking agents with disulfide bonds to prepare redox-responsive DN hydrogels and pH-responsive nanoparticles (NPs) prepared by acetalized cyclodextrin (ACD) are used to intelligently release drugs against chronic inflammation microenvironments. The addition of catechol groups and ACD-NPs loaded with the Resolvin E1 (RvE1), promotes cell adhesion and regulates the inflammatory response at the wound site. The preparation of the DN hydrogel in this study can be used to treat and regulate the inflammatory microenvironment of chronic wounds accurately. It provides new ideas for using inflammation resolving factor loaded in DN hydrogel of good biocompatibility with enhanced mechanical properties to intelligent regulate the wound inflammation and promote the wound repaired.
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PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Mingkun Gao,Guangyang Liu,Qiyue Tan,Chenxi Zhao,Ge Chen,Rongqi Zhai,Yuwei Hua,Xiaodong Huang,Jing Wang,Donghui Xu
A novel fluorescent composite (CDs@ZIF-L) was synthesized for the selective detection of Fe 3+ based on the encapsulation of Carbon dots (CDs) into Zeolitic imidazolate frameworks (ZIF) with a two-dimensional leaf-like structure. The physicochemical structure, surface morphology, and composition of the adsorbent were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and thermogravimetric analysis. The results showed that unlike the conventional three-dimensional rhombic structure (ZIF-8), the synthesized two-dimensional leaf-like nanosheets (ZIF-L) not only maintained the structural integrity but also had a permeable pore structure. Importantly, at an excitation wavelength of 350 nm, the composite's had significant fluorescence emission at 445 nm and was effectively quenched in the presence of Fe 3+ , which can be used as an effective fluorescent scaling probe. Under the optimal conditions, CDs@ZIF-L was used as a fluorescent probe to detect Fe 3+ with good linearity in the range of 0.02–2 mM (R 2 = 0.9948) and a low detection limit of 0.891 μM. The fluorescent probe can also be used for the determination of Fe 3+ in fruit samples with good recovery and accuracy, showing great potential for applications in environmental monitoring and agricultural pollutant control. It has good recovery and accuracy and shows great potential for environmental monitoring and agricultural pollutant control.
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危险品化学品经营许可证（带存储）