INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Li-Yao Zhang,Wan-Meng Song,Ping Li,Yun Liu
A phosphorus‑nitrogen synergistic flame retardant (named POI) was obtained by the chemical reaction between phenylphosphonic acid (PPOA) and polyethyleneimine (PEI), and used to give the flame retardancy of PTCO. The effects of PPOA and POI on various properties of PTCO were investigated. PPOA obviously improved the flame retardancy of PTCO/PPOA, while the breaking force of PTCO/PPOA was greatly reduced. However, the introduction of PEI made the surface of fabrics smoother. PTCO/POI had better flame retardancy than PTCO/PPOA did, and the limiting oxygen index value of PTCO/POI reached to 29.8 %. POI had a good effect on reducing the R max of both cotton and polyester components. The phosphoric acid groups in POI can promote the dehydration and carbonization reactions of PTCO, which protects the inner fabrics, and POI can release incombustible gases such as NH 3 and N 2 during burning, which can dilute the oxygen concentration. The flame-retardant mechanism of PTCO/POI was mainly the condensed phase. At the same time, there were no changes in whiteness and mechanical properties compared with those of PTCO, and it also had antibacterial property . This work provides a simple and effective method to prepare flame-retardant and antibacterial PTCO.
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高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Xinmei Qian,Chunxiang Li,Mingyu Zheng,Jinglun Wang,Haowen Huang,Keqin Deng
In this work, a regenerable magnetic omeprazole electrochemical sensor was developed for the first time. Firstly, a magnetic bamboo-like nitrogen-carbon (N-C) nanotubes encapsulated with iron-nickel alloy (FeNi) nanoparticles (FeNi@N-CNTs) was prepared by a pyrolysis route. The characterization techniques including high resolution transmission electron microscopy (HRTEM), scanning electron microscope (SEM), X-ray diffraction (XRD), energy disperse spectroscopy (EDS), and X-ray photoelectron spectroscopy (XPS) revealed the surface morphology, structure, and chemical composition of the FeNi@N-CNTs. Cyclic voltammograms (CVs) and electrochemical impedance spectroscopy (EIS) results indicated that FeNi@N-CNTs had excellent conductivity and greatly facilitated the electron transfer. By applying FeNi@N-CNTs, a designed magnetic base support, and screen-printed electrode (SPE), a regenerable magnetic SPE was developed. The presence of FeNi@N-CNTs caused better omeprazole electron transfer kinetics at SPE surface. The FeNi@N-CNTs/SPE showed a linear detection range of 0.05–25.0 μM with a detection limit of 14 nM (S/N = 3) for detecting omeprazole. Due to the FeNi@N-CNTs adhering to SPE surface by magnetic control and easy disengagement from the electrode surface by magnetism, the proposed sensor was simple, regenerable, and cost-effective.
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INORGANIC CHEMISTRY
·
2025
·
IF 4.7
Wenhan Dai,Yahan Fang,Junfeng Huang,Zhongwei Wang,Jian Li,Mudong Tu,Huijiao Wang,Jun Yang,Cailing Xu,Hua Li
To tackle the pressing issue of nitrate (NO3–) pollution in wastewater and simultaneously convert it into ammonia (NH3), Cu nanocluster-modified Rhodium (Rh) single atoms anchored on N-doped carbon were synthesized via pyrolysis of a zeolitic imidazolate framework-8 (ZIF-8) precursor and applied to the electrochemical reduction of nitrate at a low concentration. Structural characterizations (X-ray powder diffractometer (XRD), high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM), and X-ray photoelectron spectroscopy (XPS)) confirmed the coexistence of Rh single atoms and Cu nanoclusters as well as their strong electronic interactions. Mechanistic investigations revealed that Rh sites enhanced *H generation via water dissociation and promoted NO3– adsorption, thereby facilitating *H transfer and subsequent hydrogenation steps. As a result, the optimized Cu97.5Rh2.5/NC catalyst exhibited outstanding NO3–RR performance, with a Faradaic efficiency (FE) of 84.53%, an NH3 yield rate of 1252.22 μg·h–1 mgcat–1 at −1.0 V vs reversible hydrogen electrode (RHE), an NH3 selectivity of 89.13% at −1.0 V vs RHE, and a NO3– conversion rate of 93.34% at −1.1 V vs RHE. This work presents a rational design for atom-economical catalysts, enabling sustainable NH3 electrosynthesis from nitrate-laden wastewater and reducing effluent NO3––N to meet World Health Organization (WHO) drinking water standards.
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高影响因子
Future Medicinal Chemistry
·
2025
·
IF 3.4
Yan Li,Yajing Xing,Dongxia Huang,Jiuqing Xie,Yangrui Peng,Zhengfang Yi,Yihua Chen
Aim To develop potent B cell lymphoma 6 (BCL6) inhibitors, novel N-phenyl-4-pyrimidine-diamine analogs were designed and synthesized via structure-based and computer-aided drug design.Methods Starting from the hit compound ZB979, we synthesized three series of pyrimidinediamine BCL6 inhibitors (13a-13e, 14a-14c and 15a-15g) and evaluated their inhibitory activities on BCL6-SMRT interaction using homogeneous time-resolved fluorescence (HTRF) assays. The most promising candidate, compound 15d, was further assessed for its anti-proliferative activity and modulation of BCL6 downstream target genes, suppression of germinal center (GC) formation.Results Compound 15d demonstrated significant BCL6-SMRT inhibition with favorable physicochemical properties (Calculated LogP (ClogP) and topological polar surface area (tPSA)).Conclusion These findings highlight the potential of pyrimidinediamine-based scaffolds as novel BCL6 inhibitors, warranting further structural optimization to improve their efficacy.
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高影响因子
Materials
·
2025
·Vol. 18
·期 11
·2477
·
IF 3.2
Wenjie Wang,Xuan Zhang,Xianchao Wang,Chengwei Gao,Jinling Yin,Qing Wen,Guiling Wang
Natural graphite (NG) is abundant and has a high capacity for lithium-ion storage, but its narrow interlayer spacing and poor cyclic stability limit its use in high-performance lithium-ion batteries (LIBs). To address this, a N/S co-doped micro-expanded graphite composite (BFAC@MEG) was prepared by coating micro-expanded graphite (MEG) with N/S-containing amorphous carbon derived from biochemical fulvic acid (BFAC). This enhanced the electrochemical kinetics of lithium ions, improving charge transfer rates and reducing diffusion resistance. GITT results showed a higher Li+diffusion coefficient than MEG and spherical graphite (SG). BFAC@MEG exhibited excellent rate performance, robust storage capacity and remarkable cycling stability. It had a specific capacity of 333 mAh g−1at 1 C, 205 mAh g−1at 3 C, and retained 81.57% capacity after 500 cycles. Even at 5 C, BFAC@MEG exhibits a high reversible capacity of 98 mAh g−1after 200 cycles. After cycling, SEM and XPS analyses revealed a low expansion rate of 15.96% cross-sectional expansion after 300 cycles at 3 C and a stable solid electrolyte interphase (SEI) film rich in LiF and Li2CO3.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Caiyi Jiang,Peng Tang,Xiaolin Shi,Li Yang,Xingyong Liu,Bo Xing,Guo Yang,Yang Luo,Dongzheng Wang,Xiaoyu Zhao
Due to high efficiency and durability, Polyvinylidene Fluoride (PVDF) membranes are promising for their application in wastewater purification. However, they still inevitably face the challenge of membrane clogging problem, restricting separation and anti-fouling performance. Herein, a novel N-MnO x @PVDF membrane with high catalytic ozonation ability was synthesized using the blending non-solvent-induced reverse transfer method, evidenced by X-ray diffraction, Fourier transform infrared spectrometer, and X-ray photoelectron spectroscopy. Compared with pristine PVDF, N-MnO x @PVDF has better hydrophilicity and reasonable pore structure, resulting in higher permeability and anti-fouling properties. After in-situ catalytic ozonation cleaning, the Flux Recovery Ratio ( FRR ) increases from 72.1% to 99.8%, and the irreversible pollution rate ( R ir ) decreases from 31.9% to 0.13%. Meanwhile, the high stability and reusability can be demonstrated from high Total Organic Carbon (TOC) removal efficiency of humic acid (HA, 93%), high FRR (94%), and low R ir (4.3%) after consecutive cycles filtration experiments. In addition, further mechanistic insights are verified by 3D-excitation Emission Matrices (EEM) and Electron Paramagnetic Resonance (EPR) characterization, demonstrating that the removal of irreversible contaminants can be mainly ascribed to indirect oxidation of 1 O 2 , and their possible generation pathway is also proposed. This study provides valuable insights into the development of advanced antifouling membranes.
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JOURNAL OF FOOD SCIENCE
·
2025
·Vol. 90
·期 1
·e70010
·
IF 3.4
Wanyi Zhang,Qiuqi Peng,Linhan Yuan,Caiwen Wu,Mengqi Wang,Hongbo Li,Hongjuan Li,Jinghua Yu
Infant formulas are constantly being updated and upgraded, and N-glycans are functional glycans that have not been fully exploited to date. Commercial whey protein materials are often used as basic ingredients in infant formulas. Therefore, it is important to study N-glycans in commercial whey protein materials. We used matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) and ion chromatography to analyze N-glycans in bovine lactoferrin (Lf), whey protein isolate (WPI), whey protein concentrate 70 (WPC 70), goat whey protein powder 50, demineralized whey powder 90 (D90), and desalted goat whey powder. The results showed that 30, 6, 28, 16, 8, and 9 N-glycans were found in Lf, D90, desalted goat whey powder, WPI, WPC 70, and goat whey protein powder 50, respectively. A total of four structures of N-glycans were detected in this study. Only bovine Lf and WPC 70 contained fucosylated and sialylated binding (SFN-type) glycan structures. Regarding content, WPC 70 showed the highest yield of 14.5 mg/g, and the degree of sialylation was higher than fucosylation. This study provides a potential basis for the future use of commercial whey protein materials in dairy products such as infant formula.
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Journal of Materials Chemistry A
·
2025
·
IF 9.5
Qing Cheng,Yuqi Zhang,Yingying Cao,Peihao Dou,Long Liu,Yanqiang Zhang
Ionic liquid-H2O2 is a green hypergolic propellant system, and the poor self-ignition hinders its application. Herein, the stable zero-valent catalyst Cu nano-particle with twin boundaries (T-Cu) was synthesized. As the twin boundary regulates the electron micro-environment of the T-Cu surface, the electron transfer from the d electrons of Cu atom to the σ* anti-bonding orbital of H2O2 is intensified to create ·OH and ·OOH. The resulted free radicals possess strong oxidizing ability, and react violently with [BMIM]N(CN)2 to achieve a rapid ignition with the delay time as low as 25 ms. This work provides an effective way to get excellent ignition performance, and promotes the application of Ionic liquid-H2O2 green hypergolic propellants.
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高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2025
·
IF 4.3
Jin Li,Yang Wang,Tianxing Wu,Xiujing Xing,Limin Li,Wei Xiong,Hao Li
Electrocatalytic reduction of nitrate for the synthesis of high-value chemical hydroxylamine (NH 2 OH) represents a sustainable pathway that combines the dual functions of green synthesis and wastewater treatment. However, the selective control of the process is extremely challenging, mainly due to the susceptibility of nitrate to over-reduction during the reaction, leading to uncontrolled conversion of the target product NH 2 OH to the thermodynamically stable product ammonia (NH 3 ). In this paper, the Cu-PDA MOF precursor was synthesized using the emulsion method, and ZIF-8 was introduced to form the structure of Cu-PDA@ZIF-8. Subsequently, the nitrogen-carbon-doped Cu-ZnO/N-C catalysts were formed by calcination under N 2 atmosphere. The synthesized catalyst effective improved NH 2 OH selectivity during nitrate reduction. The NH 2 OH yield and FE efficiency of Cu-ZnO/N-C reached 564.97 μmol h −1 mg cat −1 and 46.64 %, respectively, under neutral electrolyte conditions. Cu, as the main component of the catalyst, plays a dominant role in hydroxylamine by electrocatalytic nitrate reduction to promote the reaction in the stage of NO 3 – →*NH 2 OH. Zn, on the other hand, plays a key role in the phase *NH 2 OH → NH 2 OH, selectively generating the product NH 2 OH and blocking the excessive reduction of NH 2 OH to NH 3 . Additionally, this study achieved tandem catalytic selective generation of NH 2 OH at copper and zinc heterogeneous interfaces and offers a potential approach and reference for applications involving the nitrate reduction reaction.
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高影响因子
ANALYST
·
2020
·Vol. 146
·期 3
·896-903
·
IF 3.978
Xiaolei Xie,Yufei Wang,Xiaobin Zhou,Junyang Chen,Mengke Wang,Xingguang Su
Single-atom nanozymes have drawn wide attention in bio-sensing for their remarkable merits such as low cost, high stability, and maximum atom utilization. Herein, a colorimetric strategy based on Fe–N–C single-atom nanozymes (Fe/NC-SAs) was established for the detection of alkaline phosphatase (ALP) activity. The Fe/NC-SAs prepared by pyrolysis have excellent peroxidase-like activity and can oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) to a blue color product in the presence of hydrogen peroxide (H2O2). When ascorbic acid (AA) is added to the system, the blue color fades, and the absorbance has a linear relationship with the concentration of AA. Alkaline phosphatase (ALP) can catalyze the hydrolysis of ascorbic acid 2-phosphate (AAP) to produce AA. Thus, a strategy based on Fe/NC-SAs for the detection of ALP activity was established, which provided a linear range of 0.1–1.5 U L−1 and a limit of detection as low as 0.05 U L−1. Besides, Fe/NC-SAs showed high stability under harsh conditions. Moreover, an Fe/NC-SA-based assay was successfully validated using human serum samples for ALP determination with satisfactory results, and has broad prospects in the field of biosensing.
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MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Jiujun Wang,Ya Wu,Qinghua Wu,Li Li,Yun Wang,Hualin Yang
Melamine has a high nitrogen content thus is often illegally added to milk powder to phonily boost the protein percentage composition. Milk products containing melamine are harmful to babies and children. In the present work, a simple, label-free and turn-on fluorescence method to detect melamine with a high sensitivity and selectivity has been developed. The N -methylmesoporphyrin IX (NMM)/G-quadruplex structure is used as a signal reporter in this method to realize label-free detection of melamine. The detection limit of this method is 12.5 nM, which is much less than the maximum level permitted for infant formulas. The linear range is 0.05–1 μM ( R 2 = 0.98). The selectivity of this method is also very satisfactory. Furthermore, this method can be successfully applied for detection melamine in raw milk and milk powder.
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高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Jiaxing Fu,Boyan Fu,Leyao Bi,Jiahui Lin,Junsheng Wen,Wenyue Tian,Chunjie Wang,Yue Wang
Given the potential risks of metabolic toxicity and organ damage associated with ethylene glycol vapor exposure, the implementation of effective monitoring is essential. In this study, LaFeO 3 -SnO 2 composites with varying mass ratios were synthesized via a hydrothermal-water bath method and subsequently evaluated for ethylene glycol sensing properties. Experimental results indicate that the LaFeO 3 :SnO 2 composite with a mass ratio of 1:2 shows the best sensing performance toward ethylene glycol among all samples. At 145 °C, it achieves a response of 89.522–100 ppm ethylene glycol, which is 435.4 % and 3137.7 % higher than the responses of pure SnO 2 and LaFeO 3 , respectively. Moreover, the operating temperature is 90 °C lower than that of pure LaFeO 3 . Meanwhile, the sensor exhibited great selectivity, repeatability and long-term stability. The improved performance could be attributed to the unique morphology of the LaFeO 3 -SnO 2 composite and the formation of a p-n heterojunction, which facilitated enhanced charge transfer and provided more active sites for ethylene glycol adsorption. Furthermore, density functional theory (DFT) calculations were performed to theoretically confirm the enhancing effect of the heterojunction on the sensing performance. This work is expected to provide new insights and serve as a valuable reference for the application of LaFeO 3 -SnO 2 gas sensors in the detection of ethylene glycol.
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危险品化学品经营许可证（带存储）