JOURNAL OF NANOBIOTECHNOLOGY
·
2021
·Vol. 19
·期 1
·1-15
·
IF 10.435
Li Yan,Wang Juan,Qian Dejian,Chen Liang,Mo Xiumei,Wang Lei,Wang Yan,Cui Wenguo
Background Most of the natural extracellular matrix (ECM) is a three-dimensional (3D) network structure of micro/nanofibers for cell adhesion and growth of 3D. Electrospun fibers distinctive mimicked 2D ECM, however, it is impossible to simulate 3D ECM because of longitudinal collapse of continuous micro/nanofibers. Herein, 3D electrospun micro/nano-fibrous sponge was fabricated via electrospinning, homogenization, shaping and thermal crosslinking for 3D tissue regeneration of cells and vascular. Results Fibrous sponge exhibited high porosity, water absorption and compression resilience and no chemical crosslinked agent was used in preparation process. In vitro studies showed that the 3D short fiber sponge provided an oxygen-rich environment for cell growth, which was conducive to the 3D proliferation and growth of HUVECs, stimulated the expression of VEGF, and well promoted the vascularization of HUVECs. In vivo studies showed that the 3D short fiber sponges had a good 3D adhesion to the chronic wound of diabetes in rats. Furthermore, 3D short fibrous sponges were better than 2D micro/nanofiber membranes in promoting the repair of diabetic full-thickness skin defects including wound healing, hair follicle regeneration, angiogenesis, collagen secretion. Conclusion Therefore, electrospun short fibrous sponges are special candidates for mimicking the 3D ECM and promoting 3D regeneration of tissue. Graphic Abstract
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS RESEARCH
·
2021
·Vol. 36
·期 14
·2961-2972
·
IF 3.089
Zhu Lijun,Zhu Xinxin,Zhang Chao,Huo Tian,Hou Xinlan,Guo Dandan,Zhang Huiming,Xia Daohong
The zirconium-based porphyrin MOFs sensitized TiO 2 (PCN224–TiO 2 ) was synthesized in situ by self-assembly of porphyrin, ZrCl 4 with nano TiO 2 . The composite catalyst was determined by detailed structural and photoelectrochemical characterization. The UV–Vis absorption and fluorescence spectrum confirm that PCN224 and TiO 2 are coupled. The PCN224–TiO 2 had significant absorption of visible light and the PCN224–TiO 2 had the largest photo-generated current, which proved the porphyrin MOFs material has good internal conductivity and has a close combination with TiO 2 . Compared with carboxyphenyl porphyrin sensitized TiO 2 (HTCPP–TiO 2 ), mixture of TCPP and TiO 2 (TCPP/TiO 2 ) and PCN224, the PCN224–TiO 2 showed better removal performance of methylene blue under visible light. Under low-power xenon lamp irradiation, the removal rate of PCN224–TiO 2 (1:3) on methylene blue reached 93.2% in 4 h. And PCN224–TiO 2 had stable cycling catalytic performance. The PCN224–TiO 2 promoted the degradation process by strengthening the adsorption of organic pollutants, thus improving the removal performance. Graphic abstract
✓ 已验证
产品关联
DOI
高影响因子
Nature Plants
·
2021
·Vol. 7
·期 8
·1026-1036
·
IF 15.793
Xiong Xingyao,Gou Junbo,Liao Qinggang,Li Yanlin,Zhou Qian,Bi Guiqi,Li Chong,Du Ran,Wang Xiaotong,Sun Tianshu,Guo Lvjun,Liang Haifei,Lu Pengjun,Wu Yaoyao,Zhang Zhonghua,Ro Dae-Kyun,Shang Yi,Huang Sanwen,Yan Jianbin
The ancient gymnosperm genus Taxus is the exclusive source of the anticancer drug paclitaxel, yet no reference genome sequences are available for comprehensively elucidating the paclitaxel biosynthesis pathway. We have completed a chromosome-level genome of Taxus chinensis var. mairei with a total length of 10.23 gigabases. Taxus shared an ancestral whole-genome duplication with the coniferophyte lineage and underwent distinct transposon evolution. We discovered a unique physical and functional grouping of CYP725A s (cytochrome P450) in the Taxus genome for paclitaxel biosynthesis. We also identified a gene cluster for taxadiene biosynthesis, which was formed mainly by gene duplications. This study will facilitate the elucidation of paclitaxel biosynthesis and unleash the biotechnological potential of Taxus .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2021
·Vol. 127
·期 7
·1-8
·
IF 2.584
Zhang Junlin,Wang Yunfan,Zhou Biao,Cao Hongyuan,Yang Xiutao,Li Bing,Zhang Jingquan,Feng Lianghuan,Zeng Guanggen,Zhong Zhengxiang,Ghali Mohsen,Karazhanov Smagul
In this work, CdS thin films were deposited on glass/fluorine-doping tin oxide (FTO) substrates by low-cost chemical bath deposition (CBD), followed by annealing with CdCl 2 -doping (Cl-doping) to fabricate resistive-type photodetectors (PDs) with a vertical structure of glass/FTO/CBD-CdS:Cl/electrode. The effect of annealing with Cl-doping (AwCl) on the various properties of films and the photodetection performance of PDs were systematically characterized by special testing methods. The results revealed that the surface morphology and crystal structure of CBD-CdS:Cl films were improved, accompanied by an enhancement of hexagonal phase (002) crystal plane (wurtzite structure), and the optical bandgap of films can be adjusted between 2.43 and 2.26 eV while the electron activation energy of the films was reduced from 75.9 to 10.3 meV after AwCl. Furthermore, the light responsivity of CBD-CdS:Cl PDs were 0.57, 0.59 and 1.67 A/W under 365, 400 and 530 nm illumination at a bias of −2.0 V, respectively, and the detectivity of photons at corresponding wavelengths were 3.7 × 10 8 , 3.9 × 10 8 and 1.08 × 10 9 Jones. Meanwhile, the PDs showed optimized repeatability and improved sensitivity under periodic illumination. The above results demonstrated that the CBD-CdS:Cl PDs with a vertical structure developed in this work had good detection performance at certain characteristic wavelengths.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 14
·18741-18750
·
IF 2.478
Qin Ruifei,Liu Lina
Multifunctional Fe 3 O 4 /Eu(DBM) 3 phen/PVP ((DBM: dibenzoylmethane, phen: 1,10-phenanthroline, PVP: polyvinyl pyrrolidone) microfibers were constructed by simple electrospinning process. The structure and morphology of the microfibers were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images. The diameters of pure PVP microfibers and the microfibers doped only with Fe 3 O 4 nanoparticles (NPs) were uniformly distributed, with an average diameter of about 360 nm. When 3% Eu(DBM) 3 phen complex and Fe 3 O 4 NPs were both added to the precursor for electrospinning, the microfibers became very inhomogeneous in diameter. The photoluminescent properties of pure Eu(DBM) 3 phen complex and composite microfibers were also studied. The characteristic emission peaks of Eu 3+ appeared in the composite microfibers. The intensities of emission and excitation spectra gradually decrease with adding more Fe 3 O 4 NPs. The unit mass of the pure europium complex in some composite microfibers gave stronger luminescence than the pure europium complex. The fluorescence lifetime of 5 D 0 state in the composite microfibers is longer than that of pure europium complex. Additionally, the magnetic properties of Fe 3 O 4 NPs and the composite microfibers were investigated. The saturation magnetization of the composite microfibers was smaller than that of pure Fe 3 O 4 NPs.
✓ 已验证
产品关联
DOI
高影响因子
Biomass Conversion and Biorefinery
·
2021
·Vol. 13
·期 8
·7175-7184
·
IF 4.987
Yang Chunyan,Zhang Liu,Zhu Yingming,Liu Yingying,Liu Changjun,Wu Kejing,Lu Houfang,Liang Bin
In this study, ordered mesoporous carbon materials are prepared to support β-Mo 2 C catalysts for conversion of Kraft lignin into aromatic monomers. Carbon supports with different porous structures are compared to discuss the critical role of ordered mesopores. The results show a volcano evolution of aromatic monomer yields with the increase in Mo contents over β-Mo 2 C supported on ordered mesoporous carbon, and a high aromatic yield of 0.576 g/g Kraft lignin is achieved at 280 °C for 3 h for only 10% Mo mass content. Dispersion of β-Mo 2 C and confinement of ordered mesopores contribute to the highest aromatic yield per unit Mo. The highly dispersed β-Mo 2 C on the surface of ordered mesoporous carbon exhibits the advances of confined environment and accessibility of lignin fragments to active β-Mo 2 C, resulting high activity of β-Mo 2 C for Kraft lignin decomposition.
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2021
·Vol. 413
·期 23
·5789-5798
·
IF 4.157
Zheng Chengyu,Zhou Qinan,Wang Zhenhe,Wang Jun
In recent years, the invasive cypress bark beetle ( Phloeosinus aubei ) has caused extensive damage to Platycladus orientalis plants in China, but its infestation is hard to monitor in the early stages. In this study, gas chromatography-mass spectrometry (GC-MS) was initially employed to investigate the volatile organic compound (VOC) emissions of P. aubei- infested P. orientalis saplings. The emissions of total sesquiterpenes were dominating (84−86% of total VOCs) and increased by 3.09-fold in P. aubei- damaged P. orientalis samples compared to undamaged samples, and the monoterpenes, aromatic compounds, and ketone emissions also had varying degrees of increase between 1.39-fold and 5.65-fold. Based on this variation, gas chromatography-ion mobility spectrometry (GC-IMS) was applied, as an untargeted analytical approach, to discriminate P. orientalis samples with different invasive severity. Two different features derived from GC-IMS data were adopted as the input information for classification and prediction models. Results showed that grid search support vector machine (GS-SVM) combined with multilinear principal component analysis (MPCA) based on spectral fingerprint achieved the best classification performances (> 88.98%), and partial least squares discriminant analysis (PLSR) method can accurately predict the pest numbers ( R 2 > 0.9423 and RMSE < 0.9827). In a word, the VOC profiling-based approach had the potential for evaluating P. aubei invasive severity and pest management.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
3 Biotech
·
2021
·Vol. 11
·期 8
·1-11
·
IF 2.406
Wang Dekang,Hu Aili,Peng Hao,Li Dongbo,Zhang Li
Glioma is the most common primary brain tumor in adults with an adverse prognosis and obscure pathogenesis. PICALM interacting mitotic regulator protein (PIMREG) functions as an oncogene in multiple types of cancer, but its function in glioma remains unknown. The Gene Expression Profiling Interactive Analysis 2 (GEPIA2, http://gepia2.cancer-pku.cn/#index ) showed that PIMREG expression in the glioma tissues was higher than that in normal brain tissues. Herein, cell counting kit-8 assay and flow cytometry analysis exhibited that overexpression of PIMREG significantly promoted the proliferation of glioma cells and the transition from G1 phase of the cell cycle to S phase. Wound-healing and transwell assays showed that overexpression of PIMREG markedly enhanced the migration and invasion of glioma cells. Western blot analysis revealed that overexpression of PIMREG increased the expression of cyclin D1, cyclin E, Vimentin, matrix metalloproteinase (MMP)-2, and MMP-9, but reduced the expression of E-cadherin. In addition, overexpression of PIMREG activated the β-catenin signaling pathway, as evidenced by the increased total and nuclear expression of β-catenin and the up-regulated expression of its downstream target c-myc. Furthermore, immunofluorescence staining further indicated the increased nuclear translocation of β-catenin in PIMREG-overexpressing cells. However, knockdown of PIMREG exerted opposite effects on glioma cells. Blockade of the β-catenin signaling by ICG-001 markedly impeded the promoting effects of PIMREG on glioma cell proliferation and invasion. In conclusion, PIMREG acts as a tumor promoter in glioma at least partly via activating the β-catenin signaling pathway. This study provides new insights into the molecular mechanism for glioma pathogenesis and treatment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Science China-Technological Sciences
·
2021
·Vol. 64
·期 9
·2003-2011
·
IF 3.572
Xu GuanPing,Zheng YouBin,Feng YanGe,Ma ShaoChen,Luo Ning,Feng Min,Chen ShouGang,Wang DaoAi
Harvesting energy from ambient environment has been considered as a promising strategy for driving portable electronic devices in a sustainable way. A wind driven triboelectric-electromagnetic hybrid nanogenerator has been fabricated to convert wind energy into electricity. It is composed of an electromagnetic generator (EMG) and a triboelectric nanogenerator (TENG) with the output power of 35 and 0.32 mW, respectively when the wind speed is 5 m/s. Generally, TENG shows a low current output with a high voltage output characteristic, on the contrary the EMG shows a high current output and a low voltage output. This hybrid nanogenerator overcomes these problems and exhibits comprehensive and efficient performance on scavenging energy. Moreover, in view of the output performance and charging ability of the hybrid nanogenerator, it shows high stability, making it suitable for charging capacitors or batteries and driving portable electronics sustainably. A new structure of integrated TENG and EMG was designed to harvest wind energy, which shows potential applications in portable and small device power supply system, especially in the areas of remote mountains, deserts, islands, etc., as emergency power supply.
✓ 已验证
产品关联
DOI
高影响因子
CATALYSIS LETTERS
·
2021
·Vol. 152
·期 5
·1386-1391
·
IF 3.186
Zhang Jiapeng,Li Yilin,Yang Lijing,Zhang Fengming,Li Ran,Dong Hua
A monolithic complexed catalyst composed of a piece of Co foam decorated with Ru nanosheets has been fabricated. This catalyst has demonstrated excellent performance in catalyzing NaBH 4 hydrolysis under alkaline conditions. Most importantly, the bulky size of the developed catalyst provides convenience to control the start and stop of hydrogen production by manipulating the attachment and detachment between the catalyst and NaBH 4 solution. These features endow this catalyst with great potential for on-site hydrogen supply. Graphic Abstract
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 13
·18397-18407
·
IF 2.478
Gao Yan,Li Ling,Li Yule,Yang Sheng’an,Ma Ji,Li Yingjuan,Qi Longfei,Yang Yunrui,Wu Dingzhang,Zhang Hui,Chen Qingming
Doping is a primary method to improve the temperature coefficient of resistance ( TCR ) and magnetoresistance ( MR ) of La 1- x A′ x MnO 3 polycrystalline in a low magnetic field. La 0.7 Ca 0.3- x Na x MnO 3 ( x = 0, 0.02, 0.04, 0.06, 0.08) series of polycrystalline were synthesized by the sol–gel method. X-ray diffraction patterns indicate that the crystal structure changes from orthorhombic to rhombohedral, and the space group changes from Pnma to \(\text{R}\stackrel{\mathrm{-}}{\text{3}}\text{c}\) with increasing x . With Na-doping rise, the increase in grain size reduces grain boundaries, weakening the electron scattering at grain boundaries and decreasing the peak resistivity. The excellent MR (59.51%) is observed in La 0.7 Ca 0.24 Na 0.06 MnO 3 at the 1 T magnetic field. Meanwhile, TCR max reaches 12.36% K −1 in the absence of a magnetic field. The resistivity variation with temperature curve fitting illustrates that grain boundary scattering dominates in the low-temperature stage, and the effect of activation energy dominates in the high-temperature stage.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Analysis and Testing
·
2021
·Vol. 5
·期 1
·3-10
·
IF 0
Huang Guo-Bin,Guo Zhi-Yong,Ye Ting-Xiu,Zhang Chen,Zhou Yan-Mei,Yao Qiu-Hong,Chen Xi
Cubic phase CsPbBr 3 perovskite nanocrystals (PNCs) was prepared by a high-temperature hot-injection method. The high photoluminescence quantum yield (PLQY) of as-prepared CsPbBr 3 PNCs was 87%, which can be used for the determination of chloridion in domestic water samples based on their wavelength-shift characteristics via halide exchange. The proposal approach for the determination of chloridion reveals a linear correlation ranged from 10 to 200 μM of the chloridion concentration and the wavelength shift of CsPbBr 3 PNCs with a correlation coefficient of R 2 = 0.9956. The as-mentioned method reveals neglectable responses towards those co-existing ions in the water aside from chloridion, due to the quick exchange between Cl and Br and the outstanding color change caused by wavelength shift. The strategy has been applied to the determination of chloridion in water samples with the recoveries of 98.9–104.2% and the limit of detection (LOD) of 4 μM. These results show that the suggested approach is promising for the development of novel fluorescence detection for chloridion in water.
✓ 已验证
产品关联
DOI
危险品化学品经营许可证（带存储）