JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2016
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IF 2.822
Fang Long,Jing Wang,Zhaohui Zhang,Liang Yan
A novel magnetic molecularly imprinted electrochemical sensor (MMIP-sensor) combined with magnetic molecularly imprinted solid-phase extraction (MMISPE) was constructed for rapid and sensitive detection of tetrabromobisphenol S (TBBPS) in water samples. The magnetic molecularly imprinted polymer based on magnetic graphene/multi-walled carbon nanotubes hybrid composite (MMIP/Gr-MWCNTs) was prepared as MMISPE sorbet to separate and enrich TBBPS from complex system. Adsorption results showed that the MMIP/Gr-MWCNTs possessed excellent selective adsorption toward TBBPS with a maximum adsorption capacity of 17.83 mg g − 1 . The magnetic imprinted sensor based on the magnetic Gr-MWCNTs composite modified electrode was prepared by electropolymerization of dopamine monomer . The high sensitivity of the MMIP-sensor was attributed to the large specific surface area and excellent electrical conductivity of the magnetic Gr-MWCNTs composites. The detection limit of the MIP-sensor toward TBBPS was calculated as 2.1 × 10 − 11 mol L − 1 (S/N = 3). Under the optimum conditions, the MISPE-MMIP-sensor combination system provided 10–12 fold preconcentration than that of MMIP-sensor alone determination. The MISPE-MMIP-sensor was successfully used for detection of TBBPS in drinking water , rain water , lake water and tap water with recoveries of 88.4–98.8%.
研究领域:
分析化学
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环境监测
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电化学传感
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分子印迹技术
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水处理
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污染物检测
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DOI
高影响因子
POLYMER TESTING
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2022
·
IF 4.931
Yang-he Mo,Hui Wang,Shao-hua Jin,Ke-lin Peng,Zi-ming Yang,Pu-wang Li,Yu Chen
Fast curing hydrogels are highly valuable in the skin care industry. Multi-arm polyethylene glycol (PEG) is a commonly used crosslinking agent for the preparation of fast curing hydrogels. However, the hydrogel preparation using multi-arm PEG crosslinking agents usually requires the end group modifications of reactants, which makes the preparation process complicated and produces hydrogels with low curing rates. In the present study, a fast in situ curing hydrogel, 4-arm-PEG-succinimidyl carbonate/carboxymethyl chitosan (PEG-SC/CMCS), was prepared using 4-arm-PEG-SC as the crosslinking agent and carboxymethyl chitosan (CMCS), a derivative of natural polysaccharide with excellent comprehensive properties, as the framework without any end groups modified. The structure and properties of the prepared hydrogel were characterized by FTIR, XRD, SEM, rheology and swelling kinetics. The effects of reaction conditions on the structure and properties of hydrogel were investigated. The PEG-SC/CMCS hydrogel exhibited pH-sensitive swelling behaviors. Its application potential in skin care products is demonstrated with its excellent sustained-release performance of Vitamin C, a model drug for skin treatment, and high adsorption capacity of heavy metal ions that are easily deposited on skin surface. Our work has provided a new strategy for building multifunctional gel materials for skin care and offered a PEG-SC/CMCS hydrogel with great application potentials.
研究领域:
生物材料
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高分子化学
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药剂学
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皮肤科学
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组织工程
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药物递送系统
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环境毒理学
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DOI
高影响因子
AAPS PHARMSCITECH
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2019
·Vol. 20
·期 1
·1-14
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IF 2.608
Wang Xingqi,Zhang Yong,Huang Jie,Tian Chunling,Xia Mengqiu,Liu Liu,Li Zhengguang,Cao Jiaojiao,Gui Shuangying,Chu Xiaoqin
The purpose of this paper was to investigate the potential of liquid crystalline (LC) gels for ophthalmic delivery, so as to enhance the bioavailability of pilocarpine nitrate (PN). The gels were prepared by a vortex method using phytantriol and water (in the ratio of 73:27 w / w ). Their inner structures were confirmed by crossed polarized light microscopy, small-angle X-ray scattering, attenuated total reflectance-Fourier transform infrared spectrum, and rheology. The in vitro release studies revealed that PN could keep sustained release from the gels over a period of 12 h. The ex vivo apparent permeability coefficient of the gels demonstrated a 3.83-folds ( P < 0.05) increase compared with that of eye drops. The corneal hydration levels of the gel maintained in the normal range of 79.46 ± 2.82%, hinting that the gel could be considered non-damaging and safe to the eyes. Furthermore, in vivo residence time evaluation suggested that a better retention performance of LC gel was observed in rabbit’s eyes compared to eye drops. In vivo ocular irritation study indicated that LC gel was nonirritant and might be suitable for various eye applications. In conclusion, LC gels might represent a potential ophthalmic delivery strategy to overcome the limitations of eye drops.
研究领域:
药剂学
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药物递送系统
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眼科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL DE MYCOLOGIE MEDICALE
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2018
·
IF 1.606
K. Xu,J.L. Wang,M.P. Chu,C. Jia
Objective The aim of this study was to investigate the antibiofilm activity of coumarin against Candida albicans . Methods The efficacy of coumarin against biofilm formation and the mature biofilm of C. albicans was quantified by crystal violet (CV) staining and the 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium hydroxide (XTT) reduction assay. The effect of coumarin on C. albicans adhesion was assessed on polystyrene plates and by using the cell surface hydrophobicity (CSH) assay. The morphological transition of C. albicans was conducted in two types of hyphae-inducing media at 37 °C. The expression of hypha/biofilm-related genes was evaluated using qRT-PCR analysis. A rescue experiment involving addition of exogenous cyclic adenosine monophosphate (cAMP) was performed to investigate the involvement of cAMP in the yeast-to-hyphae transition. A C. albicans -infected Caenorhabditis elegans model was used to test the anti-virulence efficacy of coumarin. Results Treatment with coumarin strongly affected the capacity of C. albicans to form biofilm and significantly impaired the preformed mature biofilm. The addition of coumarin notably inhibited C. albicans adhesion, CSH, and filamentation . The expression of some adhesion- and hypha-related genes, including HWP1 , HYR1 , ECE1 , and ALS3 , was remarkably down-regulated upon exposure to coumarin. Supplementation with cAMP partly rescued the coumarin-induced defects in hyphal development. Finally, coumarin prolonged survival in C. albicans -infected nematodes. Conclusion Coumarin inhibited C. albicans biofilm, which was associated with attenuated adhesion and hyphal growth.
研究领域:
微生物学
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药理学
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分子生物学
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DOI
PubMed
高影响因子
Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy
·
2019
·Vol. 29
·期 1
·46-53
·
IF 1.754
Peng Wei,Han Ping,Yu Luyao,Chen Ying,Ye Bingzhu,Qin Luping,Xin Hailiang,Han Ting
The fruits of Xanthium strumarium L., Asteraceae, have been used for various diseases in Chinese folk medicine, including allergic rhinitis, tympanitis, arthritis, ozena etc. The current study was aimed to investigate the therapeutic effects of caffeoylquinic acids from fruits of X. strumarium on allergic rhinitis in animals. The toxicity test indicated that the caffeoylquinic acids have no obvious toxicity. By using HPLC assays combined with reference standards, ten caffeoylquinic acids were identified as the predominant constituents. Anti-allergic activities of the caffeoylquinic acids were evaluated using passive cutaneous anaphylaxis test and Schultz-Dale test; dimethylbenzene induced ear edema test was performed to evaluate its anti-inflammatory effect. Then, the allergic rhinitis model in rats was established to evaluate the therapeutic effects of the caffeoylquinic acids against allergic rhinitis with the following indexes: allergic rhinitis symptom scores, serum levels of pro-inflammatory cytokines, histopathological examination, and histamine release. Our study revealed that the caffeoylquinic acids showed obvious anti-allergic and anti-inflammatory properties, and its treatments were beneficial for ameliorating the nasal symptoms, decreasing pro-inflammatory cytokines, and inhibiting the releases of histamine. Collectively, the caffeoylquinic acids might be utilized as effective and safe disease therapeutic agents for allergic rhinitis.
研究领域:
药理学
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免疫学
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过敏
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植物化学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Zhihong Han,Mingyi Tan,Daming Chen,Wenzheng Zhang,Zhipeng Lin,Jiahui Zhou,Yuhao Fang,Shengze Zhang,Qihong Wei,Xinghong Zhang,Wenbo Han
High power consumption and operating frequencies of advanced electronic devices result in significant heat generation and a complex electromagnetic environment. This creates an urgent need for materials that cover large areas, have high thermal conductivity, and offer strong electromagnetic compatibility. In this work, large-area graphite films with high thermal conductivity and excellent electromagnetic shielding properties were fabricated using glucose as a carbon source. The introduction of carboxymethyl cellulose (CMC) ensures the integrity of the film, the unidirectional shrinkage, and the template of pyrolyzed polyimide resulting in an oriented graphite structure. The graphite films exhibit in-plane thermal conductivity as high as 567 W/(m∙K), showing significant advantages in lightweight design and heat dissipation over conventional metal-based thermal management materials. The interlayer reflection structure existing in the multilayer graphite film exhibits excellent electromagnetic shielding performance, achieving an EMI shielding effectiveness of 40.79 dB in the Ku band and a shielding efficiency up to 59,399 dB·cm 2 ·g −1 with a thickness of 3 μm, significantly surpassing most reported synthetic materials. Moreover, the excellent mechanical properties further broaden the application potential of these graphite films. This research provides a renewable carbon source, pressure-free orientation and effective solution to meet the urgent demand of modern advanced electronic devices for materials with large-area, high thermal conductivity, and high electromagnetic shielding capacities.
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DOI
高影响因子
Science China-Technological Sciences
·
2025
·Vol. 68
·期 11
·1-13
·
IF 4.9
Li Xueyang,Zhang Junqiu,Shi Zijian,Wu Jiachao,Zhang Xueping,Niu Shichao,Li Bo,Song Honglie,Mu Zhengzhi,Wang Ze,Sun Tao,Han Zhiwu,Ren Luquan
Direction recognition capability is essential for intelligent systems to interact with the physical environment. However, current sensor systems often suffer from poor stability and response delays due to their complex circuit designs or multi-signal fusion algorithms. Inspired by the trichobothria on the tarsi of water striders, this study develops a bioinspired single-circuit multidirectional sensor (BSMS). By introducing an asymmetric mechanical structure with 20° directional tilt and 1/2-radius radial eccentricity, the design overcomes the axisymmetric limitations of conventional cantilever beams. By integrating a “wire-dot” heterodimensional composite conductive system, this approach achieves the resolution of multidirectional mechanical stimuli within a single sensing unit. The BSMS features an ingenious physical architecture that enables directional recognition using only a simple output circuit. The BSMS eliminates the need for multi-signal fusion algorithms while demonstrating outstanding overall performance. Its four-directional output signals exhibit 50% discrimination, along with excellent sensitivity across a wide range of 73.79–226.77 N −1 . Moreover, the BSMS shows ultra-high response consistency (>98%) and rapid dynamic response (277.35%/s response rate and 89.47%/s recovery rate). Additionally, its stability is confirmed through 100-cycle testing. Inspired by the remarkable aquatic adaptability of water striders, we applied the BSMS to obstacle detection and directional recognition for remotely operated vessels. When integrated with deep learning algorithms, the BSMS achieved over 99% accuracy in both texture identification and directional sensing. This system offers a promising solution for autonomous obstacle avoidance, precision cargo delivery, and multi-vessel coordination in complex aquatic environments. It demonstrates potential for broader applications in flexible electronics and intelligent systems.
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DOI
高影响因子
Journal of Cleaner Production
·
2025
·
IF 10
Dongyu Chen,Meizhu Chen,Xiangming Zhou,Shouwei Jian,Jianwei Zhang,Xinkui Yang,Yuechao Zhao
Minimizing indoor temperature fluctuations reduces dependence on heating and cooling systems, thereby lowering building energy consumption and carbon emissions and subsequently helping tackle global climate challenges. In this study, phase change capsules (PCCs) based on waste cooking oil derivative, Ca-alginate and nano SiO 2 were developed for foamed concrete (FC). The effects of nano SiO 2 dosage on PCC morphology, durability, thermal stability, and heat storage performance were systematically investigated. The distribution of PCCs within FC and the mechanical and thermal regulation properties of FC containing PCC were evaluated. The experimental results indicate that PCCs with 2 wt% nano SiO 2 exhibit a compressive strength of 26.29 N at 15 °C, the thermal decomposition onset above 200 °C with a notable mass loss of 40 %, and phase change enthalpy and temperature are 68.86 J/g and 20.1 °C, respectively. Ca-alginate/nano SiO 2 PCCs were uniformly dispersed and structurally intact within the FC matrix. Incorporation of 3 wt% Ca-alginate/Nano SiO 2 PCCs led to a 10.8 % reduction in compressive strength while exceeding the minimum strength requirements (>8.13 MPa) and achieving a 3.6 °C reduction in FC temperature variation. This study offers a sustainable strategy for improving building energy efficiency while promoting the recycling of waste cooking oil.
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DOI
高影响因子
Nanoscale
·
2025
·Vol. 17
·期 25
·15289-15300
·
IF 5.1
Yan Xin,Yunnian Ge,Ming Lei,Shen Cai,Chen Zhao,Huai Zhang,Huajun Tian
Zn powder anodes hold great promise for aqueous zinc-ion batteries (AZIBs) owing to their structural tunability, facile processability, and cost-effectiveness. However, their practical application is hindered by severe side reactions and uncontrolled dendrite formation, leading to rapid capacity degradation. Herein, we develop a Zn powder-based anode (ZnSn@ZP) with a Zn–Sn metal interface layer, fabricated via a simple electrodeposition strategy, to achieve uniform Zn deposition/stripping. The dense Zn–Sn interphase layer effectively mitigates anode corrosion, regulates nucleation, and suppresses dendritic growth, leading to remarkable electrochemical performance. The symmetric ZnSn@ZP cell exhibits exceptional cycling stability exceeding 1500 h at 1 mA cm−2 with an initial voltage hysteresis of 16.4 mV. The ZnSn@ZP//Cu asymmetric cell demonstrates superior average coulombic efficiency of 99.6% over 2500 cycles, indicating improved Zn deposition/stripping performance. Furthermore, the full cell assembled with the MnO2 cathode exhibits excellent cycling performance, maintaining stable cycling for 1800 cycles even at 1 A g−1 with negligible capacity decay. This work presents an effective, cost-effective and scalable interface engineering strategy, offering new insights for developing high-stability Zn powder-based anodes.
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DOI
PubMed
高影响因子
CARBON
·
2025
·
IF 11.6
Hongsheng Liang,Tian Hou,Tiancheng Liu,Shengchong Hui,Zhaoyang Hou,Zhen Wang,Bin Shi,Limin Zhang,Hao Shen,Hongjing Wu
Comprehensively understanding the role of interfacial engineering in tailoring dielectric response is essential for the development of next-generation electromagnetic wave (EMW) absorbers. Rare-earth oxides, with their flexible valence states and localized 4f orbitals, hold great potential to mediate interfacial charge transfer and polarization, yet the electromagnetic loss mechanisms underlying such effects remain unclear. Here, we demonstrate a rare-earth oxide–regulated interfacial engineering strategy, where the incorporation of CeO 2 into NiCo 2 O 4 constructs abundant heterointerfaces with dynamic valence states. Such CeO 2 -induced interfacial polarization markedly strengthens dielectric response and facilitates impedance matching, thereby surpassing the limitations of single-phase components. Dielectric analysis reveals that polarization loss dominates (>88 %) within the absorption band, while conduction loss plays a secondary role. The results show that interfacial charge redistribution driven by Ce 3+ /Ce 4+ redox flexibility, which creates abundant interfacial polarization centers and enhances relaxation. As a result, the optimized NiCo 2 O 4 /CeO 2 –T3 delivers outstanding EMW absorption, achieving a broad effective absorption bandwidth of 6.37 GHz at 2.00 mm and reflection loss of −60.09 dB at 2.20 mm (>99.99 % attenuation). This study establishes rare-earth oxide–enabled interfacial engineering as a powerful paradigm for amplifying interfacial polarization and guides the rational design of high-performance, lightweight EMW absorbers.
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高影响因子
Journal of Materials Chemistry A
·
2026
·
IF 9.2
Chunlin Ke,Siyu Song,Shenghao Li,Fengliang Wang,Ruiqi Fang,Xin Zhao,Chao Wang
High-entropy alloys (HEAs) offer immense potential for catalytic transformations, yet they suffer from severe sintering and limited active site accessibility due to their typically dense architectures. Herein, we present a facile molten salt-assisted pyrolysis strategy to confine quinary CoNiCuPtPd HEA nanoparticles within a metal–organic framework (MOF)-derived support. By using UiO-66-NH2 as a precursor, the introduced amino groups are transformed into pyridinic nitrogen sites during pyrolysis, which, along with the abundant oxygen vacancies generated in the ZrO2 phase, creates a robust porous support UNH-730. Comprehensive characterization studies (XPS and H2-TPR) confirm that the pyridinic N sites strongly anchor the metal species, facilitating the formation of homogeneously dispersed HEA nanoparticles (∼15 nm) and preventing agglomeration. In situ DRIFTS and catalytic evaluation reveal a synergistic mechanism: basic N sites and oxygen vacancies significantly enhance CO2 adsorption/activation, while the HEA sites promote H2 dissociation. Crucially, we demonstrate that light irradiation functions purely as a thermal source rather than triggering photogenerated electron–hole pairs. Consequently, the optimal CoNiCuPtPd@UNH-730 catalyst delivers a remarkable CH4 yield of 228.36 mmol g−1 h−1 with 77.8% selectivity at 550 °C under photothermal conditions substantially outperforming the ligand-free counterpart. This work establishes a novel paradigm for stabilizing multi-metal HEAs on functionalized porous carbon/oxide composites for energy conversion applications.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.6
Zhengyu Zhang,Jun Li,Zegeng Chen,Xinqi Wang,Yang Hong,Xilong Li,Dongpeng Zhao,Yang Li,Zhongxiang Zhou
Polymetallic sulfides have emerged promising in modulating dielectric response, while their phase complexity obscures the contribution of specific elements on them, hindering dielectric optimization. Herein, we report the entropy-driven engineering that controllably synthesizes the consistent MS- and M 9 S 8 -type dual-phase (M = Fe, Co, Ni, Cr, Cu, Al) structures in medium/high-entropy sulfides, which pinpoint the role of specific metals. Entropy-driven (Cu/Al) doping optimizes metallic electron transport via filling the valley regions near the Fermi level in the density of states (DOS) to boost electron mobility, and promotes S deficiency degree, culminating in a 450% conduction loss enhancement. Concurrently, it promotes charge separation in lattice disorder areas and MS/M 9 S 8 phase interfaces charge transfer capacities, boosting the disorder-interface polarization loss by 7.86 times. Therefore, the senary high-entropy sulfide (6-HES) achieves an improved effective absorption bandwidth (EAB) of 4.96 GHz. Particularly, it demonstrates practical potential through a genetic-algorithm-optimized metamaterial with an ultra-wide EAB of 11.06 GHz. This work deciphers the specific roles of entropy-driven (Cu/Al) doping in modulating electron structure, and establishes a general paradigm for designing programming dielectric properties in high-entropy systems.
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PubMed
高影响因子
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