Journal of Environmental Chemical Engineering
·
2019
·
IF 0
Alemtsehay Tesfay Reda,Dongxiang Zhang
Selective Removal of metal ions from simulated wastewater by sulfonated calix[4]arene intercalated with layered double hydroxide (SC4A-NO 3 -LDH) is reported in the present paper. The SC4A-NO 3 -LDH exhibited high adsorption performance towards metal ions with selectivity order of Fe(III) > Cu(II) > Pb(II) > Ag(I) for heavy metal ions, and Eu(III) > Nd(III) > La(III) for rare earth metal ions. Kinetics of Fe 3+ , Cu 2+ and Eu 3+ were found to follow pseudo-second-order reaction, suggesting chemisorption mechanism. Efficient sorption, with 100% removal rate and 3.80 × 10 7 mL/g distribution coefficient ( K d ) towards Fe(III) is typical potential of SC4A-NO 3 -LDH. For Cu 2+ and Eu 3+ ions sorption, K d values of 1.03 × 10 6 and 7.25 × 10 6 mL/g, and removal rates of 99.88 and 99.98%, respectively, were obtained. 0.005 g of SC4A-NO 3 -LDH was enough to lower 2.6 ppm of Fe 3+ –< 1 ppb. After the sorption, samples were characterized by analytical methods such as X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and Fourier transform Infrared spectroscopy (FTIR) and proved that the target ions on their respective samples. XRD and FTIR were also used to check the stability of the samples after sorption.
研究领域:
环境科学
·
材料化学
✓ 已验证
DOI
TALANTA
·
2013
·
IF 3.498
Hong-Jun Chen,Zhao-Hui Zhang,Rong Cai,Xing Chen,Yu-Nan Liu,Wei Rao,Shou-Zhuo Yao
In this work, an imprinted electrochemical sensor based on electrochemical reduced graphene covalently modified carbon electrode was developed for the determination of 4-nonylphenol (NP). An amine-terminated functional graphene oxide was covalently modified onto the electrode surface with diazonium salt reactions to improve the stability and reproducibility of the imprinted sensor. The electrochemical properties of each modified electrodes were investigated with differential pulse voltammetry (DPV). The electrochemical characteristic of the imprinted sensor was also investigated using electrochemical impedance spectroscopy (EIS) in detail. The response currents of the imprinted electrode exhibited a linear relationship toward 4-nonylphenol concentration ranging from 1.0×10 −11 to 1.0×10 −8 g mL −1 with the detection limit of 3.5×10 –12 g mL −1 (S/N=3). The fabricated electrochemical imprinted sensor was successfully applied to the detection of 4-nonylphenol in rain and lake water samples.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2024
·
IF 3.7
Yue Zhou,Wenjun Li,Hongjun Hu,Zhaohui Wang,Zhaoliang Cui
The membrane aeration biofilm reactor (MABR) represents an innovative approach to wastewater treatment, integrating gas separation membranes with biofilm process and demonstrating effectiveness in treating wastewater rich in ammonia nitrogen. In this system, hollow fiber membranes are essential, serving as a substrate for biofilm attachment while facilitating oxygen transfer to microorganisms through aeration, hydrophobic microporous membranes are utilized in MABR applications. This study focuses on the use of poly-4-methyl-1-pentene (PMP) hollow fiber membranes, which exhibit superior oxygen permeation capabilities compared to traditional hydrophobic microporous membranes. To overcome the challenges posed by the hydrophobic nature and low bubble point of PMP microporous membranes, a hydrophilic modification was conducted using dopamine/poly(ethyleneimine) (DOPA/PEI) co-deposition to enhance microbial adhesion on the membrane surface. The composite membrane modified with DOPA/PEI exhibited an approximately 20% higher NH 4 + -N removal efficiency than the unmodified membrane. These findings suggest that the incorporation of DOPA/PEI significantly improves MABR performance, underscoring its potential for further research and development in membrane technology for MABR.
研究领域:
环境工程
·
生物技术
·
膜科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Biomaterials Science & Engineering
·
2024
·
IF 5.4
Yuhao Zhao,Xiaofei Feng,Zhenrui Zhao,Zhengdong Song,Wenji Wang,Haiyan Zhao
In bone tissue engineering, biological scaffolds are designed with structural and functional properties that closely resemble the extracellular environment, aiming to establish a microenvironment conducive to osteogenesis. Macrophages hold significant potential for promoting osteogenesis and modulating the biological behavior of tumor cells. Multiple coculture experiments of macrophages and osteoblasts have demonstrated that macrophage polarization significantly impacts osteogenesis. Therefore, exploring bone biomaterials that can modulate macrophage polarization holds great clinical significance. In this study, heparin was modified with maleimide and was used as a raw material to form a hydrogel with 4-am-PEG-SH. The compound was used to polarize macrophages and promote osteogenesis after combining with interleukin 4 (IL-4) by taking advantage of the electronegativity of heparin. The results revealed overexpressed M2 macrophage-related phenotypic genes and cocultivation with MC3T3-E1 cells demonstrated the osteogenesis-promoting effect of the loaded IL-4 heparin hydrogel. Previous research reported that hydrogel loaded with IL-4 can be used as a biomaterial for osteogenesis promotion. Heparin materials used in this paper are derived from clinically anticoagulant drugs and feature a simple operation. The synthesized hydrogel effectively binds cytokines, regulates macrophages to induce osteogenesis and has many potential clinical applications.
研究领域:
生物医学工程
·
组织工程
·
免疫学
·
生物材料科学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Zheng Li,Jiehao Xie,Zipin Peng,Zhuo Ma,Yihui Li,Xingkun Chen,Yuan Tan,Wenshao Yang,Yunjie Ding
4-Chlorophenol (4-CP) is a pervasive environmental pollutant commonly found in wastewater and groundwater, posing great risks to both human health and the ecosystem. Catalytic hydrodechlorination (HDC) of 4-CP by utilizing hydrogen (H 2 ) as a reductant has emerged to be an efficient and sustainable way to treat pollutant water. This study focuses on the development of an efficient and stable Pd-based catalyst for the catalytic HDC of 4-CP. By incorporating an appropriate amount of Ni into Al 2 O 3 support, a NiAl 2 O 4 (NA) spinel was synthesized, enhancing the interaction between Pd and the support, leading to precise control over Pd species and oxygen vacancies. The tailored properties of the Pd/NA-1 catalyst result from meticulous adjustment of the Pd 2+ /Pd 0 ratio and oxygen vacancies, which promotes electron transfer from Pd to Ni within the NiAl 2 O 4 spinel. In comparison to the Pd/Al 2 O 3 catalyst, the Pd/NA-1 catalyst exhibits exceptional stability, with continuous operation for over 120 h without deactivation. Comprehensive characterization analyses indicate that the Pd/NA-1 catalyst effectively prevented the aggregation of Pd nanoparticles, maintaining the Pd 2+ /Pd 0 ratio at 1, which is crucial for its superior stability. This work provides valuable insights into the development of Pd-based catalysts for HDC reactions, highlighting the potential use of Pd/NA-1 catalysts in treating hazardous pollutants like 4-CP in waste systems.
研究领域:
环境科学
·
催化化学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Industrial Textiles
·
2024
·
IF 2.2
Zhendong Zhang,Jing Xiao,Chunyou Wang,Fangmiao Song,Wei Sun,Chenhui Wang,Zhisong Lu,Yan Zhang
Developing green fibrous materials with uniformly distributed metal nanoparticles for highly efficient and recyclable catalysis remains a major challenge. Herein, we developed a simple, effective, and green method to immobilize gold nanoparticles (AuNPs) on polydopamine (PDA)-functionalized silk fibers (SFs) for efficient catalytic reduction of 4-nitrophenol (4-NP). The density and size of AuNPs on the PDA-coated SFs can be tuned by adjusting precursor concentration and synthesis duration, respectively. The AuNPs-PDA-SFs catalysts prepared under optimized conditions could catalyze the reduction of 4-NP, 4-nitroaniline (4-NA), and 4-amino-3-nitrophenol (4-A-3-NP) at the apparent rate constants of 0.087, 0.091, and 0.063 min−1, respectively. After six rounds of flow-through reduction of 4-NP, the AuNPs-PDA-SFs could maintain a 4-NP conversion rate greater than 92%, indicating their superior reusability and consistent catalytic activity. Due to the protein properties of SFs, the AuNPs-PDA-SFs can be degraded by enzymes and alkali solutions. This work may provide new insights for designing advanced fiber-supported recyclable catalysts with high catalytic performance and reusability in wastewater treatment.
研究领域:
材料科学
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环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yanqing Zheng,Xiheng Kang,Zi You,Yihan Li,Yongheng Huang,Tieguang He,Tianming Su,Arthur J. Ragauskas,Zhenglong Li,Qiong Wang,Xueping Song
As an “upstream” process in biorefinery, biomass dismantling can dismantle the natural stable structure of lignocellulosic biomass and separate its three major components. To increase the value of the entire biomass by fully utilizing the three main components (cellulose, lignin, and hemicellulose), this study proposes a two-step decomposition system combining formic acid (FA) pretreatment and ethylene glycol-NaOH (EGA) dismantling, aiming to effectively convert sugarcane bagasse into xylose, fermentable glucose, and high-value lignin. In the first step, FA pretreatment removed 79.85 % of hemicellulose at 140 °C for 90 min with 3 % FA. Based on the first step, further combination of EGA dismantling can achieve a hemicellulose removal rate of 92.05 % and a lignin removal rate of 95.90 %. In addition, the solid residue was hydrolyzed by enzymes, and the glucose conversion rate was close to 83.29 % when the cellulase dosage was 10 FPU/g. In addition, the lignin recovered by this system retained 83.62 % of the natural β-O-4 structure, which has the potential to catalyze the formation of aromatic monomers. In summary, this gentle two-step system simultaneously improves the efficiency of lignocellulose decomposition and produces different value-added products, demonstrating the potential for industrial-scale production.
研究领域:
生物化学
·
生物质能工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MATERIALS & DESIGN
·
2025
·
IF 7.9
Lifang Xie,Tianxiang Yuan,Su Hu,Chenmin Zhao,WenLi Huang,Wei Ding,Ye Zhang,Xianwen Hu
Chronic diabetic wounds exhibit impaired healing due to a complex interplay of pathological mechanisms, including persistent hyperglycemia, excessive matrix metalloproteinase-9 (MMP9) activity, and chronic inflammation, which disrupt tissue repair and regeneration. A central driver of this dysregulated healing is macrophage polarization imbalance, with excessive pro-inflammatory M1 and insufficient reparative M2 macrophages, prolonging inflammation and delaying tissue remodeling. To address these challenges, we developed a dual-responsive hydrogel composed of phenylboronic acid-functionalized polyethyleneimine (PEI-PBA), polyvinyl alcohol (PVA), and Benzaldehyde-PEG-Benzaldehyde (DF-PEG-DF) for controlled co-delivery of interleukin-4 (IL-4) and salvianolic acid A (SalA). This dynamically crosslinked hydrogel responds to the diabetic wound microenvironment, enabling pH- and glucose-triggered release. IL-4 promotes M2 macrophage repolarization, resolving inflammation and enhancing tissue repair, while SalA scavenges reactive oxygen species (ROS) and inhibits MMP9 activity, preserving extracellular matrix (ECM) integrity and supporting regeneration. In vivo, the hydrogel significantly accelerated wound closure in diabetic mice by promoting M2 polarization and reducing MMP9-mediated matrix degradation. This coordinated modulation of the inflammatory and proteolytic microenvironment attenuated inflammation, enhanced angiogenesis, and increased collagen deposition, collectively facilitating tissue regeneration. These findings suggest this intelligent hydrogel is a promising therapeutic strategy for chronic diabetic wound healing with translational potential.
研究领域:
生物材料
·
药物递送
·
糖尿病创面修复
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免疫调控
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再生医学
✓ 已验证
产品关联
DOI
高影响因子
BRAIN RESEARCH
·
2025
·
IF 2.6
Xingli Tan,Xiaoli Su,Ying Wang,Weiwei Liang,Di Wang,Di Huo,Hongyong Wang,Yan Qi,Wenmo Zhang,Ling Han,Dongmei Zhang,Ming Wang,Jing Xu,Shuyu Wang,Jing Wang,Honglin Feng
Dysregulation of copper and iron homeostasis contributes to the progression of amyotrophic lateral sclerosis (ALS), but the role and mechanism of COMM domain containing 4 (COMMD4) in ALS remains unclear. In this research, we showed that the expression of COMMD4 was upregulated in ALS cells and animal models. The increased COMMD4 induced neuronal ferroptosis by disrupting the Cu-Fe balance. Mechanistic studies indicated that COMMD4 inhibited ferroportin (FPN)-mediated neuronal iron efflux by inhibiting intracellular copper and hephaestin (HEPH). Our findings demonstrated that COMMD4 depletion exerts neuroprotective effects on ALS by increasing intracellular copper and activating HEPH/FPN pathway, rather than affecting the interaction between HEPH and FPN. Targeting COMMD4 and its downstream signaling pathways may offer potential therapeutic avenues for ALS.
研究领域:
神经生物学
·
分子生物学
·
医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POULTRY SCIENCE
·
2025
·
IF 4.2
Yuxin Shao,Yipu Li,Shuxian Xie,Bo Zhang,Jing Li,Yalei Wang,Yusheng Gao,Jianyuan Ma,Tenghe Ma,Zheng Wang
This study aimed to evaluate the effects of 4-hydroxyphenylacetic acid ( 4-HPAA ), a phenolic acid compound from Yucca schidigera extract, in Caco-2 cells and artificial rearing of pigeons. In vitro experiments showed that 4-HPAA at different levels exhibited higher cell viability than shikimic acid and 3,4-dihydroxybenzoic acid, and with the highest viability observed at 600 μM. Additionally, 600 μM 4-HPAA alleviated LPS-induced upregulation of IL-1β and CASPASE1 expressions ( P < 0.05) . In vivo results demonstrated that supplemental 4-HPAA at 500, 1000, and 2000 mg/kg levels did not affect the body weight of 25-day-old pigeons ( P > 0.05), but all levels increased immunoglobulin G ( IgG ) and IgM levels ( P < 0.05). Compared with control, 2000 mg/kg 4-HPAA significantly reduced serum L-lactic acid, D-lactic acid and lactate dehydrogenase ( LDH ) activity ( P < 0.05); increased spleen and bursa of Fabricius indices and intestinal total antioxidant capacity activity of 25-day-old pigeons ( P < 0.05); and elevated ileal barrier-related genes ( OCCLUDIN, CLAUDIN1 and MUC2) in 7-day-old pigeons, as well as jejunal MUC2 and ileal OCCLUDIN in 25-day-old meat pigeons ( P < 0.05). It also inhibited glycolytic gene hexokinase 2 expression, while upregulating the signaling pathway genes CAMK2G and MKNK1 ( P < 0.05). Supplemental 500 and 1000 mg/kg 4-HPAA significantly increased serum total cholesterol levels ( P < 0.05). Notably, 500 mg/kg 4-HPAA had an adverse effect on intestinal integrity, as indicated by the highest serum diamine oxidase content, and increased glycolytic gene LDH-B expression; However, it enhanced microbial richness and diversity in the intestines of 7-day-old pigeon ( P < 0.05). Besides, 1000 mg/kg 4-HPAA impaired intestinal morphology, as evidenced by a lower ileal villus height-to-crypt depth ratio ( P < 0.05), but resulted in the highest abundance of Lactococcus in 25-day-old pigeons. In conclusion, 600 μM 4-HPAA exhibits anti-inflammatory activity in Caco-2 cells, and 2000 mg/kg 4-HPAA promotes immune function and intestinal barrier integrity while inhibiting glycolytic gene expression and the production of related serum metabolites in meat pigeons.
研究领域:
兽医学
·
营养学
·
分子生物学
·
动物科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Catalysts
·
2025
·Vol. 15
·期 3
·263
·
IF 4
Kaijie Li,Qin Wang,Qifan Zhao,Hongbo Yu,Hongfeng Yin
In this article, Pt-SnxOyhybrid nanoparticles encaged in porous silica nanospheres (Pt-SnxOy@PSNs) were prepared by using 1-dodecanethiol (C12-SH) as a coordination agent to confine Pt and Sn ions in a microemulsion system, which is formed by cetyltrimethylammonium bromide (CTAB) and C12-SH as co-surfactants in water. Compared with Pt@PSNs, when different molar ratios of SnxOywere introduced into Pt@PSNs to form Pt-SnxOy@PSNs, the catalytic efficiency of 4-nitrophenol (4-NP) reduction with NaBH4can be significantly enhanced. At molar ratios of 4-NP/Pt of 150/1, the 4-NP conversion reached 100% over Pt-SnxOy@PSNs with Pt/Sn molar ratios of 1/0.75 in 8 min. This catalytic performance showed a slight decrease after six reaction cycles. This enhanced catalytic efficiency can be ascribed to the synergistic effect between Pt and SnxOy,and the protection of porous silica nanostructures can effectively improve the stability of the catalyst.
研究领域:
材料科学
·
催化化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Liming Yang,Yanjun Cui,Bing Hu,Qian Yang,Xia Xu
Perovskite quantum dots (PQDs) offer high photoluminescence quantum yields. However, their poor stability and aqueous-quenching of fluorescence limit their wider application, especially in biochemical detection. In this work, a simple and highly successful coating strategy was used to encapsulate Mn2+-doped CsPbCl3 PQDs in poly(ethylene glycol) (PEG), effectively increasing the water stability of PQDs. After dispersion in deionized water for 25 days, the CsPbCl3/Mn2+/PEG nanocrystals (NCs) retained 40% of their initial fluorescence intensity. In addition, due to the FRET mechanism, 4-nitrophenol (4-NP) can effectively quench the fluorescence of CsPbCl3/Mn2+/PEG NCs. Therefore, utilizing the excellent water stability of CsPbCl3/Mn2+/PEG NCs and their interaction with 4-NP, a fast and conservative fluorescent probe can be established, which can perform highly selective and ultrasensitive quantitative detection of 4-NP in aqueous solutions. In addition, the molecular weight of PEG used for encapsulation, the fluorescence intensity of CsPbCl3/Mn2+/PEG NCs, and the detection range for 4-NP vary. Fortunately, the detection limits are all lower than the drinking water concentrations allowed by the U.S. Environmental Protection Agency. This study also provides a theoretical basis and methodological support for the subsequent application of PQDs in the detection of water pollutants.
研究领域:
材料科学
·
纳米技术
·
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）