查找使用阿拉丁产品的科研文献

Phase-adapted Metal Ion Supply for Spinal Cord Repair with a Mg-Zn Incorporated Chimeric Microsphere

Xiangyu Liu,Biao Ma,Sihan Hu,Dandan Li,Chun Pan,Zhuobin Xu,Hao Chen,Yongxiang Wang,Huihui Wang

Dynamic alterations in metal ion concentrations are observed in the pathological process of spinal cord injury (SCI). Hence, strategically supplying metal ions in a phase-adapted manner is promising to facilitate injured spinal cord repair by preventing pathological damage. To achieve this, a chimeric hydrogel microsphere with Mg 2+ -crosslinked methacrylate gelatin as the "shell" and Zn 2+ -loaded poly (lactic-co-glycolic acid) (PLGA) as the "core" was designed. The chimeric microspheres allow continuous delivery of Mg 2+ or Zn 2+ at the exact required phase in SCI pathological process. Early release of Mg 2+ reduced inflammation by diminishing the secretion of proinflammatory cytokines due to changes in macrophage polarization, which further suppressed scar formation to create an ideal space for neural regeneration. The subsequently released Zn 2+ at the late phase effectively promoted neural cell proliferation and regeneration, which was accompanied by activation of mature neurons, interneurons, and motor neurons, leading to significant behavioral recovery. Thus, this study underscores the critical role of metal ions at different phases of injured spinal cord repair and describes the construction of an injectable chimeric hydrogel microsphere carrying distinct metal ions with a core-shell structure. Chimeric microspheres overcome the discrepancy between the inflammatory response and neural regeneration and are a promising therapeutic strategy for injured spinal cord repair.

Preparation of a cationic hydrogel microsphere adsorbent for efficient removal of hexavalent chromium from aqueous solution

Yuansong Ye,Yuchi Zhang,Huazhong Wu,Run Fang

Herein, a cationic hydrogel microsphere (CHMS) was prepared by inverse suspension polymerization and freeze-drying and was applied to the adsorptive removal of hexavalent chromium (Cr(VI)) from aqueous solution. Morphological characterization shows that there are lots of folds and pores on the surface of CHMS with a unique petal-like appearance. According to the chemical structure analysis, CHMS contains plenty of functional groups such as amine and hydroxyl groups. These features give CHMS a larger specific surface area, faster adsorption rate, and higher adsorption capacity than the conventional cationic hydrogel microparticle (CHMP) adsorbent. The adsorption of Cr(VI) in water by CHMS is mainly based on the combination of electrostatic adsorption and redox reaction, with the electrostatic interaction between the protonated amine and Cr(VI) serving as the predominant adsorption mechanism. Experimental results reveal that CHMS can efficiently remove Cr(VI) from simulated wastewater in both batch and continuous adsorption modes, which is primarily due to its distinctive surface morphology and rich functional groups. Furthermore, the common coexisting metal ions in Cr(VI)-containing wastewater have no substantial negative influence on the adsorption. Therefore, it can be concluded that CHMS has a promising application prospect in the treatment of Cr(VI)-containing wastewater.

Enhanced Sensitivity and Versatile Detection: Dual-Sized Microsphere-Type Pressure Sensors for Soft Robotics and Wearable Electronics

Xiying Li,Jia Ming Zhang,Huiling Duan

The development of pressure sensors with enhanced sensitivity, expanded working range, and versatile yet decoupling detection capabilities is critical for advancing robotics and medical applications. This work presents a novel pressure sensor design utilizing the distinct responses of dual-sized microspheres to external pressure that achieves a high sensitivity of 20 kPa–1 and an expanded pressure range of 0.1–70 kPa, enabling continuous and precise pressure detection. Functional material coatings further enhance the performance of the sensor, demonstrated here with a PEDOT:PSS layer for temperature sensing with a sensitivity of 4 × 10–5 K–1, while effectively decoupling temperature and pressure signals. The resulting bimodal sensor features a rapid pressure response (200 ms), low hysteresis, and exceptional durability, maintaining reliable performance over 3000 cycles. With its simple fabrication process and robust sensing capabilities, the sensor is validated through diverse applications, including gesture recognition, tactile perception in soft robotics, and handwriting detection using sensor arrays. This sensor design with dual-sized microspheres demonstrates significant potential for next-generation electronic skin, perceptive robotics, and intelligent wearable electronics, offering a versatile and practical approach to multifunctional sensing.

In-doped SmFeO3 nanoblocks-assembled microsphere composited on graphene gas sensor for ppb-level aniline gas detection

Huai Wang,Zhenyu Yuan,Renze Zhang,Mengran Ran,Liyun Qin,Hanyang Ji,Kaiping Yuan,Fanli Meng

Aniline is not only a type of carcinogen but also the raw material for the preparation of drugs. Therefore, the detection of aniline is of great significance in human health and environmental protection. In this paper, rGO-SmFeO 3 -In nanocomposites were prepared by hydrothermal method for the detection of aniline by combining the excellent properties of rGO and In. The lattice, micro-morphology, elemental distribution and chemical state of the gas-sensitive material were analyzed through XRD, SEM, EDS, and XPS characterizations, which confirmed that the In-doped SmFeO 3 (SFO) nanoblocks-assembled microspheres composited on rGO were successfully prepared, and the nanocomposite possessed abundant oxygen vacancies. The gas sensitivity test results showed that 2 wt% rGO-SFO-1.5 wt% In had excellent gas sensitivity to aniline gas. At 200℃, 2 wt% rGO-SFO-1.5 wt% In had a higher response value of 64.2–100 ppm aniline, which was 6 times that of SFO, and showed a faster response and recovery process (10 s/5 s). In addition, the sensor demonstrated its ability to detect aniline at a lower detection limit of 1 ppb with a response rate of 1.25. Furthermore, the gas sensor was integrated into the embedded system to achieve real-time detection of aniline gas. This study provides a new reference for the development of low detection limit and high sensitivity aniline gas sensor.

The self-supported Zn-doped CoNiP microsphere/thorn hierarchical structures as efficient bifunctional catalysts for water splitting

Xiaoyan Wang,Ying Xie,Wei Zhou,Xiuwen Wang,Zhicheng Cai,Zipeng Xing,Mingxia Li,Kai Pan

The hierarchical electrocatalysts with the superaerophobic property are in favor of removal of gas bubbles and supply of numerous active sites to improve the electrochemical catalytic activity for water splitting. In this work, the self-supported Zn-doped CoNiP (Zn–CoNiP/NF) hierarchical structure that consisted of nanothorns and radial microspheres were prepared with via a facile precursor phosphorization method. Zn-doping could tailor the initial electronic state of CoNiP to improve the hydrogen or oxygen atom binding, which effectively promoted the catalytic kinetics of water splitting. The hierarchical structure not only offered more catalytic active sites for water splitting, but also facilitated gas releasing due to the superaerophobic interface. The hierarchical Zn–CoNiP structure showed a high hydrogen evolution reaction (HER) efficiency in electrolytes with pH 0–14, which yielded low overpotentials of 73 mV in acidic solution and 34 mV in alkaline media at current density of 10 mA cm −2 . Furthermore, it also had evidenced by an overpotential of 310 mV for oxygen evolution reaction (OER) at the current density of 50 mA cm −2 . Note that the required cell initial voltage was 1.51 V for overall water splitting. These results were comparable or even better than many non-noble catalysts.

Compressive properties of co-continuous hollow glass microsphere/epoxy resin syntactic foams prepared using resin transfer molding

Junjie Ding,Qiang Liu,Feng Ye,Haoqian Zhang,Ye Gao,Biao Zhang

In this article, the co-continuous hollow glass microspheres (HGMs)/epoxy resin syntactic foams were prepared by filling the HGM preforms with epoxy resin. The effects of HGM wall thickness and solid loading on the density, open porosity, and morphology of HGM preform and HGM/epoxy resin syntactic foams were studied in detail. The results show that the HGM wall thickness had no effect on the open porosity of HGM preforms. However, the density of preforms increased with the true density of HGMs. The density of HGM/epoxy resin syntactic foams decreased with the contents of HGMs, and the measured density was essentially equal to the theoretical density. The compressive strength decreased with the contents of HGM, regardless of the HGMs wall thickness. However, the variation in compressive modulus was related to the HGMs’ wall thickness. As the HGM solid loading increased, the compressive modulus of composites, prepared using thin-walled HGMs, decreased, while the composites prepared using thick-walled HGMs showed the opposite trend. The co-continuous HGM/epoxy resin syntactic foams possessed low density (0.567–1.002 g/cm3), and excellent compressive strengths (30.32–131.60 MPa). These properties were due to the elimination of matrix pores, and are a type of promising material in deep sea exploration area.

Engineering a polyaniline nanoneedles-coated multi-layered Co3O4/NiO microsphere as high-performance Li-ion battery anode

Zhen Peng,Xiaojie Yin,Tianli Han,Jiawei Long,Jinpei Hei,Jinyun Liu

High energy-storage Li-ion battery needs a high-capacity anode. However, current graphite-based anode doesn’t meet this requirement, thus developing high performance anode materials is highly needed and significant. Here, we provide a rational engineering of a multi-layered hollow structure combining with surface coating of polyamine (PANI) layer, forming a Co 3 O 4 /NiO@PANI hybrid using for Li-ion battery anode. PANI is able to effectively improve the conductivity of active materials; besides, PANI is flexible, which can prevent the collapse of the structure caused by volume-expansion during charge and discharge. The multi-layered morphology improves the utilization ratio of voids inside the conventional hollow structured materials, which is significant to improve capacity in practical applications. The Co 3 O 4 /NiO@PANI hybrid-based anode shows a capacity of 1049 mAh g −1 along with a Coulombic efficiency of 99.3% after 100 cycles of 0.2 A g −1 . Rate-performance of Co 3 O 4 /NiO@PANI exceeds that of the bare Co 3 O 4 /NiO. It is believed that the hierarchical structure combining multi-layered hollow morphology with surface coating of conductive polymer presented here would find broad applications for developing high-performance energy-storage hybrids.

A Biomimetic Layered Silk Fibroin Microsphere Modulating Redox Homeostasis and Enhancing Osteogenic Differentiation for Synergistic Periodontal Regeneration

Yajuan Hu,Xuemin Ma,Haiyin Wan,Peirong Zhou,Yongcen Chen,Huiyue Wang,Xia Wang,Junliang Chen,Rui Cai,Yun He,Gang Tao

Periodontitis-associated alveolar bone loss results from a persistent inflammatory and oxidative microenvironment that impairs regenerative healing. To address this challenge, we developed a biomimetic, spatially stratified silk fibroin (SF)-based microsphere system (Cu/Ce-TA@HA-SF) that restores redox homeostasis and serves as a bone filling material to support periodontal bone regeneration. The microsphere features a three-layered architecture: a SF core produced via microfluidic technology ensures uniformity and adjustable mechanical properties, facilitating dynamic structural support during regeneration and adaptation to irregular defect sites. Surrounding the core, a hydroxyapatite (HA) layer enhances osteoconductivity, while the outer Cu 2+ /Ce 4+ –tannic acid (TA) nanozyme shell imparts antibacterial and reactive oxygen species (ROS)-scavenging functionality. The nanozyme exhibits catalase CAT- and SOD-like activities, effectively scavenging ROS, restoring mitochondrial function, and preserving human periodontal ligament stem cell (hPDLSC) viability. Notably, the microspheres inhibit ROS-induced pyroptosis via suppression of the NLRP3/Caspase-1/GSDMD signaling pathway. Concurrently, redox modulation regulates immune responses by activating Nrf2 and inhibiting NF-κB signaling, thereby suppressing M1 macrophage polarization and enhancing M2 phenotypes. In vivo, Cu/Ce-TA@HA-SF microspheres achieved coordinated inflammation resolution, angiogenesis, and alveolar bone regeneration in a rat periodontitis model. This multifunctional, hierarchically engineered microsphere offers a promising strategy for redox-driven immunomodulation and functional periodontal regeneration.

Selective adsorption and separation of Cr(VI) by surface-imprinted microsphere based on thiosemicarbazide-functionalized sodium alginate

Yapei Luo,Heng Li,Minghua Wu,Wei Wang,Lili Wang

Hierarchical hollow microsphere and flower-like indium oxide: Controllable synthesis and application as H2S cataluminescence sensing materials

Pingyang Cai,Wei Bai,Lichun Zhang,Hongjie Song,Yingying Su,Yi Lv

In the present work, In 2 O 3 hierarchical hollow microsphere and flower-like microstructure were achieved controllably by a hydrothermal process in the sodium dodecyl sulfate (SDS)- N , N -dimethyl-formamide (DMF) system. XRD, SEM, HRTEM and N 2 adsorption measurements were used to characterize the as-prepared indium oxide materials and the possible mechanism for the microstructures formation was briefly discussed. The cataluminescence gas sensor based on the as-prepared In 2 O 3 was utilized to detect H 2 S concentrations in flowing air. Comparative gas sensing results revealed that the sensor based on hierarchical hollow microsphere exhibited much higher sensing sensitivity in detecting H 2 S gas than the sensor based on flower-like microstructure. The present gas sensor had a fast response time of 5   s and a recovery time of less than 25   s, furthermore, the cataluminescence intensity vs. H 2 S concentration was linear in range of 2–20   μg   mL −1 with a detection limit of 0.5   μg   mL −1 . The present highly sensitive, fast-responding, and low-cost In 2 O 3 -based gas sensor for H 2 S would have many practical applications.

Preparation and characterization of the linked lanthanum carboxymethylcellulose microsphere adsorbent for removal of fluoride from aqueous solutions

Jing Wang,Xiaoyan Lin,Xuegang Luo,Wenhui Yao

Linked carboxymethyl cellulose microspheres loaded with lanthanum(III) (linked-CMC–La) were fabricated with glutaraldehyde, from lanthanum carboxymethyl cellulose microspheres (CMC–La), and used to remove fluoride from aqueous solution. Characterization by SEM, resistance to acid and alkali, TG, pHpzc and FT-IR was used to distinguish the superiority of the two adsorbents. The results showed that the linked-CMC–La had a higher decomposition temperature (200 °C) than CMC–La (190 °C) and a better resistance to acid and alkali compared with CMC–La. Batch adsorption experiments were also performed, varying factors of pH, initial fluoride concentration, and contact time. The results showed that the maximum removal efficiencies (REs) of CMC–La and linked-CMC–La were about 98.85% and 99.31%, respectively, when the fluoride concentration was 40 mg L−1 at pH 4.0. The adsorption process could be described well using the Langmuir isotherm model. The adsorption kinetics data was fitted well using a pseudo-second-order model. The analysis of the adsorption and desorption of the linked-CMC–La and CMC–La revealed that crosslinking had no obvious effect on the removal efficiency or mechanism of the adsorption and desorption of the two absorbents. The surface adsorption occurred between the linked-CMC–La and fluoride due to Lewis acid–base interaction and supplemented with electrostatic attractions.

A robust inorganic coated separator enabled by polyacrylate-modified microsphere binders for high safe lithium-ion batteries

Fei Song,Yinghao Xia,Hui Wang,Dejian Cheng,Guangzhao Zhang,Jingyuan Wang,Yong Zeng,Heyu Tang,Ao Jiao,Yu Yang,Yonghong Deng,Chaoyang Wang

Polyethylene separators (PE) are widely used in lithium-ion batteries due to their good electrochemical stability and low cost. However, PE separators have issues including high-temperature shrinkage and poor electrolyte wettability, which reduce the safety and electrochemical performance of batteries. In this work, we synthesized a large-sized microsphere binder (SNE) and designed an inorganic ceramic/polymer composite coating strategy. The prepared single-layer PE/SNE separator exhibits a unique micro-convex structure, where microspheres with diameters slightly larger than the thickness of the ceramic layer are partially exposed outside the composite coating. The electrodes and separators are hot-pressed to make the microspheres viscoelastic, which effectively bonds the electrodes, prevents sliding, and strengthens the interface to reduce interface impedance. Compared to traditional PVDF-coated ceramic separators, PE/SNE separators feature simple production processes, lower cost, and environmental friendliness. The ceramic-coated optimized PE/SNE separator can maintain shrinkage of <1% at 130 °C/0.5 h and improves the ionic conductivity (0.83 mS/cm) and lithium-ion transference number (t Li +  = 0.62). Due to the optimized hot-pressed interface and improved overall performance of the PE/SNE separator, the NCM622//Li cell has a discharge capacity of 118 mAh/g at 5C, and the NCM622//graphite full cell has a capacity retention rate of 81% after stable cycling for 1500 cycles at 2C. This approach offers a promising method for developing lithium-ion battery separators with enhanced safety and cycling performance.