SPECTROSCOPY LETTERS
·
2025
·
IF 1.6
Shuaibin Wu
In this study, a novel surface enhanced Raman scattering (SERS) substrate material was designed and prepared for the real-time Rhodamine 6 G SERS detection. Firstly, ZIF-67 was modified on the surface of polypropylene membrane by in-situ growth methods. Subsequently, the pre-prepared Ag nanoparticles were modified on the surface of the polypropylene membrane through the covalent reaction. The result of scanning electron microscopy characterization showed that Ag nanoparticles was modified on the surface of ZIF-67 through simple electrostatic adsorption and the chemical reaction of the Ag-S bond; The infrared characteristic peaks of ZIF-67, as well as the x-ray diffractometer and x-ray photoelectron spectrometer characteristic peaks of ZIF-67 and Ag nanoparticles could all be identified. On the other hand, based on this material, we have investigated the feasibility of conducting real-time SERS detection under optimized conditions when the sample was in a flowing situation. The experimental results showed that the SERS detection of Rhodamine 6 G could be completed within 15 min in the mode of real-time, with an relative standard deviation of 10.67%. The concentration of Rhodamine 6 G and the intensity of the SERS signal also have a good linear relationship within the range of 103, 5 × 102, 2.5 × 102, 25 and 10 μmol/L.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Nanke Ma,Yuwei Chen,Liya Wang,Ping Tan,Nayu Chen,Yuan Jin,Jian Song,Guangli Li
Conductive hydrogels have garnered significant attention for flexible electronics, yet simultaneously achieving optimal mechanical robustness and electrical performance under harsh conditions remains challenging. Herein, an ion/electron dual-mode conductive Ag/AgCl@Agar/P(AM- co -HEAA) hydrogel was developed for wearable motion detection and electrophysiological signal monitoring. The hydrogel exhibited outstanding mechanical properties, including excellent stretchability (2207 %), high tensile stress (0.32 MPa), and remarkable toughness (3.90 MJ/m 3 ). As a strain sensor, it displayed high sensitivity (GF of 4.17 within 1100–1400 % strain), stable and reproducible resistance signal output across both micro-strains (0.01–0.1 %) and macro-strains (200–1400 %), and excellent working durability and reliability (200 cycles at 200 % strain). Notably, it also demonstrated reliable sensing performance even at −20 °C due to the ion/electron hybrid conductive mechanism. These unique properties enabled the hydrogel successfully applied in real-time human motion detection and human-machine interaction. Moreover, the hydrogel semi-dry electrodes displayed low potential drift (4.64 μV/min) and electrode-scalp impedance (13.2 ± 1.6 kΩ at 10 Hz). Significantly, the hydrogel electrodes achieve clinical-grade ECG and EEG signal acquisition, comparable to commercial wet electrodes. These superior properties, combined with facile fabrication, make this multifunctional hydrogel a promising candidate for next-generation wearable devices in motion monitoring and human–machine interactions.
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Peng Liu,Huimin Deng,Huijun Chen,Jiaoyang Li,Liangyi Hong,Huimin Zou,Xingyan Zhou,Hian Kee Lee,Zhenzhen Huang
Choline in human breast milk is crucial for infant neurodevelopment. However, choline concentration variation in human breast milk remains understudied. In this work, a colorimetric biosensor of bovine serum albumin@Hemin@Ag nanozyme was developed, leveraging its peroxidase-like activity to oxidize 2,2′-azino-bis(3ethylbenzo-thiazoline-6-sulfonic acid) diammonium salt in the presence of hydrogen peroxide generated from choline oxidation by choline oxidase. Under the optimal conditions, a wide linear range (1–500 μM) and a low limit of detection (0.55 μM) were obtained for choline quantification. Longitudinal analysis of paired human breast milk samples revealed a significant decline in choline level from 15- to 90-d postpartum, influenced by maternal diet during pregnancy and pre-pregnancy body mass index. This research not only provides a robust tool for evaluating breast milk's quality, but also underscores the importance of diet during pregnancy and body mass index management for lactating mothers.
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DOI
PubMed
高影响因子
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
·
2025
·
IF 7
Wei Feng,Jian Zhang,Ruxia Liu,Yong Xiao,Guoqiang Luo,Qiang Shen
Particle-reinforced composite fillers allow precise control of joint microstructure to enhance mechanical performance. However, traditional designs often reduce joint deformability and face issues like particle agglomeration and poor interfacial wettability. To overcome these limitations, a micro-network of Cu-Ti reinforcements within the brazing seam via Ag- x TiH 2 composite filler was developed in this work, which enabled the fabrication of high-strength Si 3 N 4 /Cu joints. Optimal results were achieved with the Ag-4TiH 2 filler, wherein a eutectic liquid formed at the Ag-4TiH 2 /Cu interface during the initial brazing stage. Simultaneously, undissolved Ti reacts with Cu to yield submicron Cu 4 Ti 3 -dominated reinforcements. On the Si 3 N 4 surface, hypostoichiometric TiN/TiN 0 . 61 /TiN 0 . 5 nanocrystals grow sequentially, which is beneficial for enhancing interfacial wettability and bonding reliability. A maximum average shear strength of 186.9 MPa was obtained, a 57.6 % improvement over the conventional AgCuTi filler. The fracture mechanism underwent a notable transformation: brittle failure at mixed regions of Si 3 N 4 and the reaction layer in AgCuTi joints was replaced by ductile failure at the interface between the Cu matrix and the brazing seam in Ag-4TiH 2 joints. The Cu 4 Ti 3 -dominated micro-network offers distinct advantages by enabling controllable in-situ growth that prevents agglomeration while maintaining joint deformability through the synergy effect of the abundant retention of ductile Ag(s, s) and decent elastic modulus and yield strength increment, and regulates the interface reaction to yield a thinner Ti-N layer instead of a TiN/Ti 5 Si 3 dual-layer. These features collectively contribute to the notable mitigation of residual stress within Si 3 N 4 /Cu joints.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2016
·
IF 4.758
Li Liu,Yueyuan Li,Lihui Tian,Qin Wei,Wei Cao
A novel and ultrasensitive sandwich-type electrochemical immunosensor was designed for quantitative detection of prostate specific antigen (PSA). The Ag overgrowth in Pd nano-octahedrons, developed Pd-Ag heterodimers (Pd-Ag HDs), loaded on amino functionalized multiwalled carbon nanotubes (MWCNTs-NH 2 ) were employed as labels of secondary antibodies (Ab 2 ). The synergistic effect of Pd-Ag HDs exhibited high electrocatalytic activity towards the reduction of H 2 O 2 . MWCNTs-NH 2 with good dispersion , plentiful amino groups and large specific surface area , could load a large number of Pd-Ag HDs to enhance the sensitivity and amplify the signal of the immunosensor. Moreover, the electroplated gold nanoparticles (Au NPs) were employed for the immobilization of primary antibodies (Ab 1 ). Au NPs with excellent conductivity could enhance the electron transport between substrate material and electrode surface , and improve the sensitivity of immunosensor. Under optimal conditions, the electrochemical immunosensor exhibited a wide linear range of 0.1 pg/mL–30 ng/mL towards PSA, and a low detection limit of 0.03 pg/mL (S/N = 3). The proposed immunosensor exhibited good sensitivity, reproducibility and stability for the quantitative detection of PSA, which hold a great potential in clinical and diagnostic applications.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2017
·
IF 4.233
Yi Xie,Litong Chen,Xiang Zhang,Shengqiu Chen,Man Zhang,Weifeng Zhao,Shudong Sun,Changsheng Zhao
Development of antibacterial membranes is strongly desired for biomedical applications. Herein, we integrated antifouling and bactericidal properties on polymeric membrane surface via Schiff-based layer-by-layer (LbL) assembly. Zwitterionic polymers bearing plentiful amino groups (based on polyethylenimine (PEI) and sulfobetaine methacrylate (SBMA), and termed as PEI-SBMA) were utilized to prepare an antifouling membrane surface; then robust wide-spectrum bactericidal Ag nanoparticles (Ag NPs) were in situ generated on the surface. The as-prepared zwitterionic polymer surface showed excellent resistance to protein adsorption and bacterial adhesion. The Ag NPs could be tightly and uniformly distributed on the membrane surface by the chelation of PEI-SBMA, and endowed the membrane with bactericidal activity. Meanwhile, the Ag NPs loaded membrane could effectively resist bacterial attachment for a long time, even though the bactericidal activity lost. The proposed bactericidal and antifouling membrane was flexible, versatile and could be large-scale preparation; and this strategy would have great potential to be widely used to avoid undesired bacterial contamination of biomedical implants or biological devices.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Yuqian Guo,Yaofeng Zhou,Sicheng Xiong,Lifeng Zeng,Xiaolin Huang,Yuankui Leng,Yonghua Xiong
The usage of nanozyme as label to establish immunoassays offers merits of low cost and high robustness. However, the catalytic activity of nanozyme is usually passivized by the modified layer of bio-recognition molecules. The peroxidase-mimicking activity of cetyltrimethylammonium bromide (CTAB)-coated gold nanoparticles (AuNPs@CTAB) is recovered by Ag + ions. Herein, AuNPs@CTAB with Ag + -triggered catalytic activity was first designed as signal transducer to construct colorimetric immunoassay for human chorionic gonadotropin (HCG) detection. Silver nanoparticles were used as labels which can release numerous Ag + ions by hydrogen peroxide corrosion and thus enhance the catalytic activity of AuNPs@CTAB. To achieve the highest detection sensitivity, we synthesized three kinds of AuNPs@CTAB with similar size but different shapes including nanospheres (AuNSs@CTAB), nanorods (AuNRs@CTAB), and nanocubes (AuNCs@CTAB). The morphology-dependent catalytic properties of AuNPs@CTAB were evaluated. Under optimum conditions, the proposed method using AuNSs@CTAB, AuNRs@CTAB and AuNCs@CTAB using AuNSs@CTAB, AuNRs@CTAB and AuNCs@CTAB gave LOD of 7.8, 15.6 and 31.2 mIU/mL, respectively. The developed immunoassays also showed good accuracy, high reproducibility and high robustness for detecting HCG in serum samples. In summary, the developed immunoassay is a promising bioanalysis platform which can provide similar sensitivity and enhanced robustness compared with traditional horse radish peroxidase-based immunoassays.
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高影响因子
JOURNAL OF DAIRY SCIENCE
·
2022
·
IF 4.225
Bolong Fang,Juan Peng,Gan Zhang,Keyu Xing,Wenyao Chen,Daofeng Liu,Shan Shan,Yonghua Xiong,Weihua Lai
ABSTRACT Escherichia coli O157:H7 is a type of hazardous bacteria in the field of food safety. A sensitive and effective method is urgently needed to detect it, avoiding enormous harm for the human health. In this study, we synthesized stable Ag + -doped gold nanoclusters (Ag-AuNC) with a fluorescence intensity 4.8 times stronger than that of AuNC. It was further demonstrated that Ag 0 existing in the AuNC core and a fraction of Ag + anchored on the AuNC shell eliminated the surface defects and improved the luminescent properties of AuNC. A combination of I 2 and I − was used to quench fluorescence-enhanced Ag-AuNC, which was first applied in ELISA for detecting E. coli O157:H7 to improve the sensitivity. In the presence of E. coli O157:H7, the biotinylated anti- E. coli O157:H7 mAb and streptavidin-alkaline phosphatase would be immobilized and catalyze l -ascorbic acid 2-phosphate sesquimagnesium salt hydrate to produce ascorbic acid. After addition of KIO 3 , I 2 /I − were generated. The I 2 could trigger oxidative etching of Ag-AuNC and I − could combine with Ag + to decrease the Ag + concentration of Ag-AuNC, which resulted in fluorescence quenching of Ag-AuNC. Under optimal conditions, the linear range of I 2 /I − -mediated fluorescence quenching of Ag-AuNC-based immunoassay for detecting E. coli O157:H7 was 3.3 × 10 3 to 10 6 cfu/mL, with a detection limit of 9.2 × 10 2 cfu/mL, 10.7-fold lower than that of the traditional ELISA. The proposed immunoassay exhibits excellent sensitivity, specificity, recovery, and accuracy, which is useful for quantitative detection of E. coli O157:H7 in food safety.
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高影响因子
APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Linlin Sun,Xiaoshuo Liu,Xiaohan Jiang,Yibing Feng,Weijie Yang,Nan Jiang,Jigang Wang
Many optimization strategies have been applied to the construction of materials with excellent organic contaminants removal activity, whereas the interaction mechanisms of these strategies have rarely been revealed. Here, based on the analysis and evaluation of CeO 2 -decorated hierarchical tremella-like Ag/g-C 3 N 4 (Ce@15-AC) materials, the mechanism of oxidation activity enhancement is studied in depth. Finite–difference time–domain (FDTD) simulations and density functional theory (DFT) calculations reveal the mechanism of local surface plasma resonance (LSPR) effects and interfacial electric fields. The synergistic effect of the Z-scheme electrons transfer direction and Ce 4+ /Ce 3+ redox couple conversion enable Ce@15-AC to achieve the maximum redox capacity. The hierarchical structure can generate scattering and reflection of sunlight and provide a variety of channels for light transmission. Moreover, experiments and characterizations prove that Ce@15-AC material has fantastic photoelectrochemical, physical and optical properties. The removal efficiency of tetracycline (TC) by Ce@15-AC reaches 91.7% within 40 min (20 mg/L, 100 mL), and TC is almost completely degraded after 60 min. The apparent reaction rate constant (k) of Ce@15-AC is approximately 0.05974 min −1 , which is 10.71 times higher than 3DT-CN (0.00558 min −1 ). This work provides a meritorious instance in the advanced oxidation of organic contaminants application field.
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高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 7
·1-10
·
IF 5.479
Lv Hui,Zhang Xiaobo,Li Yueyun,Ren Yong,Zhang Chunyan,Wang Ping,Xu Zhen,Li Xinjin,Chen Zhiwei,Dong Yunhui
A voltammetric sandwich immunoassay is described for the biomarker cardiac troponin I (cTnI). The gold nanocube-functionalized graphene oxide (AuNC/GO) is employed as a substrate to accelerate the electron transfer and to immobilize more primary antibodies. It also employs composite materials prepared from bimetallic gold/silver core-shell nanocubes and nitrogen and sulfur co-doped reduced graphene oxide as the signal amplifier. The introduction of N and S into GO enlarges the active surface and accelerates the electron transfer rate. Such unique characteristics render the material an effective support substrate to load more Au@AgNC and to immobilize an increasing number of second antibodies via Ag-N bonds. After specific binding with cTnI, the immunosensor was incubated in a labeled cTnI secondary antibody solution. The amperometric signal change is then measured at 0.34 V (vs. SCE) using o-phenylenediamine and hydrogen peroxide as an electrochemical probe. Response is linear in the concentration range from 100 fg∙mL −1 to 250 ng∙mL −1 , and the detection limit is 33 fg∙mL −1 .
Schematic presentation of cardiac troponin I (cTnI) electrochemical immunosensor based on gold nanocube-functionalized graphene oxide (AuNC/GO) as substrate material, bimetallic gold/silver core-shell nanocubes and nitrogen and sulfur co-doped reduced graphene oxide (Au@AgNC/N, S-rGO) as signal amplifier, and hydrogen peroxide (H 2 O 2 ) and o-phenylenediamine (o-PD) as redox probe.
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高影响因子
SOLAR ENERGY MATERIALS AND SOLAR CELLS
·
2023
·
IF 6.9
Jiayong Zhang,Bin Yao,Zhanhui Ding,Yongfeng Li,Ding Ma,Mengge Li,Yuting Sun,Chunkai Wang,Yue Liu,Xiaofei Sun
Although trace silver (Ag) substitution for Cu in Cu 2 ZnSn(S, Se) 4 (CZTSSe) offers benefits in improving open-circuit voltage (V OC ) of CZTSSe solar cells, its further development is still hindered by the fairly low short-circuit current density (J SC ) owing to the increase of bandgap (E g ) of the absorber layer . Herein, a strategy is demonstrated to mitigate the poor J SC arising from the Ag substitution by tuning the Cu 2+ /(Cu + +Cu 2+ ) percentage in the (Cu, Ag) 2 ZnSnS 4 (CAZTS) precursor solution . Depth characterization indicates that the appropriate Cu 2+ /(Cu + +Cu 2+ ) percentage in the CAZTS precursor solution increases the photogenerated charges separation and carrier transport processes for Ag-substituted CZTSSe (CAZTSSe) solar cells. Benefiting from this strategy, the power conversion efficiency (PCE) of 9.57% is achieved when the Cu 2+ /(Cu + +Cu 2+ ) is 50 at.%. The main factor for the improvement of PCE is due to the increase in photogenerated current density (J L ) and decrease in shunt resistance (R sh ). It is demonstrated that the increase in J L results from a widening in the depletion layer width (W d ) of the p-n junction and an increase in carrier lifetime, induced by optimization of the Cu 2+ /(Cu + +Cu 2+ ) percentage. While the decrease in R sh comes from the change of reaction pathways due to the change in Cu 2+ /(Cu + +Cu 2+ ) percentage.
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高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2020
·
IF 5.647
Yang Wang,Pengcheng Gao,Yingying Wei,Yajin Jin,Si Sun,Zhifei Wang,Yong Jiang
A facile and cost-effective preparation of silver nanoparticles decorated magnetic composite for the effective catalytic degradation of 4-nitrophenol (4-NP) and Methylene blue (MB) and Rhodamine B (RhB) was investigated. Fe 3 O 4 @Polystyrene@Ag (Fe 3 O 4 @PS@Ag) catalyst was prepared via a two-step procedure. Firstly, carboxyl groups modified magnetic microspheres (Fe 3 O 4 @PS-COOH) has been successfully synthesized by microemulsion polymerization. Then Ag ions were adsorbed and in-situ reduced on the surface of Fe 3 O 4 @PS microspheres . To estimate the catalytic activity of Fe 3 O 4 @PS@Ag catalyst, the reduction experiments of MB, RhB and 4-NP were performed in the presence of NaBH 4 . The results indicated that Fe 3 O 4 @PS@Ag catalyst has a good catalytic performance and these dyes can be reduced in a very short time, which the apparent rate coefficients are 0.0089 s −1 , 0.0187 s −1 and 0.0086 s −1 for MB, RhB and 4-NP respectively. In addition, it could be easily collected from aqueous solution by a magnet so that the catalyst could be recovered and reused after the catalytic process. The catalytic activity was still high after seven cycles. This catalytic reaction is in agreement with the pseudo-first-order kinetic equation . Furthermore, the as-prepared Fe 3 O 4 @PS@Ag catalyst outperforms other catalysts in the degradation of these organic dyes.
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高影响因子
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