APPLIED CATALYSIS B-ENVIRONMENTAL
·
2023
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IF 22.1
Yayun Pu,Yufei Liu,Xiaosheng Tang,Qiang Huang,Limin Huang
Realizing bifunctional catalysts for the HER and OER in a unified environment bears the promising goal of reducing the cost and complexity of electrolyzer devices. Dual atoms configuration intrinsically active to hydrogen/oxygen evolution is a feasible way to achieve that target. In this work, Co, Ir active species were selected to be inserted into the interlayer space of layered V 2 O 5 , forming a two-dimensional confined structure that significantly improves the atomic efficiency. During the electrochemical water splitting in alkaline medium, the V-O framework that encapsulated the active species in layered V 2 O 5 was collapsed and disrupted due to its acidic nature. The HER/OER active Co, Ir were readily released and exposed to the reactant. In situ structure evolution was monitored and elaborately analyzed by operando Raman, TEM and XPS characterizations. Further, DFT calculation disclosed that the Co atom was covalently stabilized by the nearest oxygen that leads to electron-depleted Co. The stabilization of Ir was achieved by forming both a covalent bond with oxygen and a metallic bond with sublayer V. This, however, resulted in a changed electron distribution in Ir, leading to better binding with oxygenate intermediates and improved OER activity. As for the alkaline HER, the potential determining step (PDS) of IrCo@V 2 O 5 is predominately determined as the OH desorption, regardless of the H evolution pathway of Volmer-Tafel or Volmer-Heyrovsky. The bifunctional IrCo@V 2 O 5 acted like a “Trojan Horse” and achieved an ultrahigh mass activity of 848 A g -1 Co,Ir for the OER and 461 A g -1 Co,Ir for the HER. This work provides new insight into creating highly effective electrocatalysts via the in situ releasing methodology.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2025
·
IF 21.1
Luna Ruan,Xinyu Han,Lihua Zhu,Congxiao Shang,Anna Kroner,Kaijie Liu,Yibo Zhang,Bing Hui Chen,Zhengxiao Guo
Metal nanoparticles are widely considered for heterogeneous catalysis due to their high atomic efficiency and tunable active microenvironment, but their specific functional tendencies are still unclear. Here, we report that a Rh@ZrO 2 /NC catalyst with only 0.1 wt% Rh exhibits exceptional catalytic performance and high selectivity (p-nitroacetophenone conversion-98.6 %, p-aminoacetophenone selectivity-100 %, r -56.4 mol p-nitroacetophenone /(mol Rh ·min)) towards the hydrogenation of the -NO 2 group in nitroarene to -NH 2 . This is because the interaction between Rh species and “ZrO 2 -N” results in significant hydrogen spillover in the catalyst, as supported by DFT calculations. Extensive characterizations from TG, DTG, NAP-XPS, in-situ Raman spectroscopy, in-situ DRIFT spectroscopy and DFT calculations further confirm the adsorption, activation and dissociation of hydrogen on Rh nanoparticles. The H* species migrate readily over ZrO 2 -NC, to facilitate the catalytic activity and selectivity for the hydrogenation of nitroarene. This study presents a new approach to develop highly efficient and selective metal nanoparticle-catalysts for cost-effective hydrogenation reactions.
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MEASUREMENT
·
2025
·
IF 5.6
Yongsheng Zhang,Jian Yuan,Tao Xu,Yang Wang,Xiaonan Chen,Hua Yao,Wanxue Li,Lei Dong,Weiguang Ma,Lei Zhang,Wangbao Yin,Suotang Jia
Understanding the elemental composition of polymetallic minerals, particularly strategic metals, is essential for optimizing the development and utilization of critical mineral resources. This study introduces a rapid, cost-effective analytical method for the determination of strategic metals in polymetallic minerals using an in-house developed total reflection X-ray fluorescence (TXRF) system. This system is equipped with an Rh X-ray tube, a four-knife slit, a silicon drift detector, and Python-based spectral processing software, achieving detection limits ranging from 104.94-4.22 mg kg −1 for elements with atomic number (Z) from 11 to 38 and 86. Solid samples were prepared as suspensions by mixing 10 mg of powder in 1 mL of ethylene glycol, and Ga as internal standard was added. The quantitative analysis accuracy of the system was validated using cobalt-rich nodule standard reference material. Its application to real-world copper-nickel sulfide ores exhibited a strong linear correlation with inductively coupled plasma atomic emission spectroscopy (R 2 = 0.9929) and yielded results comparable to those obtained with a commercial Mo-TXRF spectrometer (R 2 = 0.9919). These findings were demonstrated the suitability of the in-house developed TXRF system for the analysis of polymetallic minerals, and provide a valuable reference for its application.
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高影响因子
FOOD CONTROL
·
2024
·
IF 5.6
Han Wang,Lele Shao,Yingying Sun,Yana Liu,Bo Zou,Yijie Zhao,Yuhan Wang,Xingmin Li,Ruitong Dai
This study investigated the alterations in cellular structure of ohmic heating (OH)-induced injured Staphylococcus aureus ( S. aureus ) during repair in nutrient broth, and the potential antibacterial approach of combining OH with food bacteriostatic agents and their application in milk. Specifically, the biological properties (surface hydrophobicity, zeta potential, particle size) and indicators related to cell membrane and cell wall integrity (peptidoglycan content, activities of β-galactosidase, alkaline phosphatase, and lactate dehydrogenase) of injured S. aureus during repair were measured. Additionally, scanning electron microscope and transmission electron microscope analyses were used to observe morphological changes, and protein changes were analyzed using fourier transform infrared spectroscopy and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The results suggested that OH destroyed the biological properties and membrane structure (membrane integrity and permeability increased, cell wall integrity increased, protein and functional group of membrane were damaged) of S. aureus , which could be partially restored after repair. However, the restoration process between cell membrane and cell wall were inconsistent, and morphological changes reinforce these findings. Notably, membrane proteins and functional groups on the bacterial cell surface were difficult to repair. Also, OH combined with low doses of bacteriostatic agents is a potential method to ensure food safety. Carvacrol and low temperatures could inhibit the repair of injured bacteria in pasteurized milk; and reduce precipitate formation and putrid gas production.
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高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2024
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IF 5.7
Ying Liang,Zi Wang,Deyang Huo,Jun-nan Hu,Lingjie Song,Xiaochi Ma,Shuang Jiang,Wei Li
In recent years, there has been a growing concern regarding health issues arising from exposure to nanoplastics (Nps) in the natural environment. The Nps bioaccumulate within the body via the circulatory system and accumulate in the liver, resulting in damage. Previous studies have demonstrated that maltol, derived from red ginseng (Panax ginseng C.A. Meyer) as a Maillard product, exhibits hepatoprotective effects by alleviating liver damage caused by carbon tetrachloride or cisplatin. In order to explore the specific mechanism of maltol in improving hepatotoxicity induced by Nps, mice exposed to 100 mg/kg Nps were given maltol at doses of 50 and 100 mg/kg, respectively. The results showed that Nps induced an increase in the levels of liver apoptotic factors BAX and cytochrome c, a decrease in the levels of the autophagy key gene LC3 II/I, and an increase in P62. It also caused oxidative stress by affecting the Nrf2/HO-1 pathway, and a decrease in GPX4 protein expression suggested the occurrence of ferroptosis. However, treatment with maltol significantly improved these changes. In addition, maltol (2, 4, and 8 μM) also protected human normal liver L02 cells from Np (400 μg/mL)-induced damage. Our data suggest that maltol could ameliorate Np-induced L02 cytotoxicity by reducing autophagy-dependent oxidative stress, exhibiting similar protective effects in vitro as in vivo. This study helps shed light on the specific molecular mechanism of Np-induced hepatotoxicity. For the first time, we studied the protective effect of maltol on Np-induced liver injury from multiple perspectives, expanding the possibility of treatment for diseases caused by environmental pollutants.
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PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Meixi Chen,Jun-Hu Cheng,Da-Wen Sun
Graphene oxide (GO), renowned for its two-dimensional structure and exceptional fluorescence quenching capabilities, is a preferred choice for the construction of fluorescence biosensors. As the sensitivity demands for these sensors escalate, enhancing the fluorescence quenching performance of GO and reducing background fluorescence become paramount to optimize the sensor sensitivity. In this study, the use of cold plasma (CP) treatment with glucose solution as a reducing agent to refine GO into reduced graphene oxide (r-GO) with optimal fluorescence quenching abilities was explored. The efficacy of CP treatment was comprehensively analyzed, encompassing fluorescence quenching capacity, morphological alterations, and structural composition. The findings revealed that the ideal conditions for achieving r-GO with superior fluorescence quenching were achieved by treating a mixture of 0.5 mg/mL GO and 0.2 g/mL glucose with CP at 100 kV and 1 A for 10 min. Notably, the resulting r-GO demonstrated remarkable performance in the specific detection of tropomyosin in shrimp, achieving a detection limit of 0.0657 μg/mL, demonstrating its potential for highly sensitive biosensing applications.
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PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2025
·
IF 14.3
Yanhui Cao,Junhao Zeng,Xuerong Zheng,Yuan Liu,Junda Lu,Jinfeng Zhang,Yang Wang,Yida Deng,Wenbin Hu
Oxygen reduction reaction (ORR) in neutral electrolyte is urgently needed in various areas, such as metal-air batteries. However, the N-coordinated transition-metal single-atom electrocatalysts confront sluggish catalytic kinetics due to the inappropriate electronic structure and the as-resulted unreasonable adsorption strength towards oxygen-containing intermediates. In this work, we develop a strategy to tune the Fe d-orbital spin state by introducing inert Si atom into the first coordination sphere of Fe-N 4 moieties. The experimental and theoretical results suggest that Si atom generates the coordination field distortion of Fe and induces the Fe d-orbital spin state transforming from low to medium spin state. The optimized spin-electron filled state (t 2g 4 e g 1 ) of Fe sites weakens the adsorption strength to intermediates and reduces the energy barrier of *OH desorption. Consequently, Fe-Si/NC catalyst exhibits superior ORR performance compared with that of Fe-NC and commercial Pt/C, showing a more positive half-wave potential of 0.751 V (vs. RHE) in 0.1 mol/L phosphate buffered saline. In addition, Fe-Si/NC-based neutral zinc-air batteries show a maximum power density of 108.9 mW cm −2 and long-term stability for more than 200 h. This work represents the possibility of constructing distorted coordination configurations of single-atom catalysts to modulate electronic structure and enhance ORR activity in neutral electrolyte.
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高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2024
·
IF 5.6
Mengdi Qin,Guangshuai Zhang,Peixu Zhao,Genyang Ye,Mo Li,Xiwei Jiang,Xiaohong Liu,Qiang Fu,Zhonggui He
Thiol-modified hyaluronic acid (HASH) improves zein nanoparticles (ZNPs) stability by disulfide bonding with zein. However, the effect of the degree of thiol substitution in HASH on the stability of the ZNPs remains unclear. In this study, HASH with 1%, 3%, and 5% degrees of thiol substitution was synthesized and used as stabilizers to prepare three composite NPs. The pH and salt ion stability of the composite NPs increased with increasing degree of thiol substitution, which improved the antioxidant and anti-inflammatory capacities of the composite NPs. Interestingly, when the degree of thiol substitution exceeded 3%, the physical stability of composite NPs did not improve further. Our results revealed the relationship between the degree of thiol substitution in HASH and the stability of ZNPs, and provided the optimal degree of thiol substitution. These findings provided important information for improving the physical stability of ZNPs and contributed to the development of a delivery system for natural actives.
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高影响因子
CORROSION SCIENCE
·
2025
·
IF 8.5
Fengting Li,Wentao Qu,Yunchao Peng,Liqiang Yang,Li Wang,Huiling Su,Miantuo Li,Zhikun Wang,Jingyue Wang,Yu Fu,Songqing Hu
In this study, we developed ionic liquid-modified nitrogen-doped carbon dots (IL-NCDs) with enhanced π-π interactions, effectively addressing the aggregation issue of conventional carbon dots in strong acidic conditions. The synthesized IL-NCDs demonstrated superior dispersibility and long-term protective performance in 1 M HCl, achieving a corrosion inhibition efficiency of 97.34 % at 60 mg/L and maintaining protection for over 20 days. The optimized surface charge and increased active sites facilitated the formation of a dense protective film, offering an efficient and eco-friendly solution for metal corrosion protection in acidic environments, with significant potential for industrial applications.
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高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2024
·
IF 5.3
Ying Yu,Shuang Ren,Lixia Shang,Baoyan Zuo,Guofei Li,Jingxin Gou,Wei Zhang
Tranexamic acid (TXA) is an anti-fibrinolysis agent widely used in postoperative blood loss management. As a highly water-soluble drug, TXA is suffering from rapid clearance from the action site, therefore, large amount of drug is required when administered either by intravenously or topically. In this study, a TXA preparation with prolonged action site residence was designed using the nano-micro strategy. TXA nanoparticles were dispersed in oil by emulsification followed by lyophilization to give a solid-in-oil suspension, which was used as the oil phase for the preparation of TXA-loaded solid-in-oil-in-water (TXA@S/O/W) system. The particle size of TXA in oil was 207.4 ± 13.50 nm, and the particle size of TXA@S/O/W was 40.5 μm. The emulsion-in-gel system (TXA@S/O/G) was prepared by dispersing TXA@S/O/W in water solution of PLGA-b-PEG-b-PLGA (PPP). And its gelling temperature was determined to be 26.6 ℃ by a rheometer. Sustained drug release was achieved by TXA@S/O/G with 72.85 ± 7.52 % of TXA released at 120 h. Formulation retention at the joint cavity was studied by live imaging, and the fluorescent signals dropped gradually during one week. Drug escape from the injection site via drainage and absorption was investigated by a self-made device and plasma TXA concentration determination, respectively. TXA@S/O/G showed the least drug drainage during test, while more than 70 % of drug was drained in TXA@S/O/W group and TXA solution group. Besides, low yet steady plasma TXA concentration (less than 400 ng/mL) was found after injecting TXA@S/O/G into rat knees at a dosage of 2.5 mg/kg, which was much lower than those of TXA dissolved in PPP gel or TXA solution. In conclusion, sustained drug release as well as prolonged action site retention were simultaneously achieved by the designed TXA@S/O/G system. More importantly, due to the steady plasma concentration, this strategy could be further applied to other highly water-soluble drugs with needs on sustained plasma exposure.
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PubMed
高影响因子
Nature Catalysis
·
2022
·Vol. 5
·期 10
·900-911
·
IF 40.706
Li Peng,Jiang Yaling,Hu Youcheng,Men Yana,Liu Yuwen,Cai Wenbin,Chen Shengli
The origin of the large kinetic pH effect in hydrogen electrocatalysis, that is, the approximately two orders of magnitude decrease in reaction kinetics when moving from acid to alkaline, remains far from having a consensus. Here we show that it is the significantly different connectivity of hydrogen-bond networks in electric double layers that causes the large kinetic pH effect. This result has been obtained by meticulously comparing the electric double layers of acid and alkaline interfaces from ab initio molecular dynamics simulations, and the computed vibrational density of states of water molecules in the interfaces simulated with ab initio molecular dynamics, with the results of in situ surface-enhanced infrared absorption spectroscopy. Using a Pt–Ru alloy as a model catalyst, we further reveal an unanticipated role of OH adsorption in improving the kinetics of alkaline hydrogen electrocatalysis, namely, by increasing the connectivity of hydrogen-bond networks in electric double layers rather than by merely affecting the energetics of surface reaction steps. These findings highlight the key roles of electric double layer structures in electrocatalysis.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Boyi Liao,Lei Li,Wenqi Liang,Huimin Lin,Ben Hu,Kexin Wang,Renli Huang,Peiqi Wang,Qining Weng,Yuanchen He,Yue Cao,Meng Yu,Zhaowei Zou
Sepsis is a life-threatening condition characterized by organ dysfunction caused by a dysregulated host response to infection. An inflammatory intestinal environment, disruption of the intestinal epithelial barrier, impairment of the mucus layer, and dysregulation of the gut microbiome can lead to pathogen translocation and increased susceptibility to sepsis. Hence, an orally administered nanomedicine is developed, S-Z@M nanoparticles (NPs), based on food-derived mussel adhesive protein (M)-modified zeolitic imidazolate framework-8 (Z) for the targeted delivery of anti-inflammatory herbal medicine. S-Z@M NPs exert multi-therapeutic effects by forming a physical barrier at injured intestinal sites and persistently activating anti-inflammatory pathways. First, S-Z@M NPs scavenge reactive oxygen species (ROS) to reduce oxidative stress injury. After ROS-triggered charge transition and oxidative cross-linking, the M layer adheres to the negatively charged damaged mucosa to form a physical barrier, preventing further damage from microorganisms and toxins. Sinomenine (S) releases from Z NPs in response to an acidic environment suppresses pro-inflammatory pathways, thereby inhibiting intestinal epithelial cell apoptosis and restoring intestinal tight junctions and gut microbiota homeostasis. Overall, S-Z@M NPs show a strong potential to regulate the inflammatory microenvironment and restore intestinal barrier function, opening the door for further exploitation in sepsis therapy.
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