ACS Applied Energy Materials
·
2021
·
IF 6.024
Qiang Chang,Liu Yao,Wenping Zha,Meifen Wu,Fangfang Xu,Zhaoyin Wen
Silicon is an attractive anode material for the high-energy-density lithium-ion battery due to its high theoretical capacity (4200 mA h g–1). However, larger volume expansion (∼300%) and pulverization during cycling hinder the commercialization of silicon anodes. The modification of silicon materials is a widely recognized approach to enhance the anode performance, but the volume expansion cannot be solved completely when only focusing on the active material but ignoring the overall structural optimization of the anode. In the study, additional hierarchical pores were constructed in the electrodes by in situ partial pyrolysis of the binder sodium carboxymethyl cellulose (CMC) at low temperature. Benefiting from the extra buffer space, the electrodes can accommodate more expansion and enhance the conduction of electrons and ions. In addition, the partially degraded CMC reduced the adsorption energy between the binder and the active material, reducing the stress during the swelling process, which is demonstrated by density functional theory. The as-obtained electrode delivered a high reversible capacity of 1035 mA h g–1 at 1000 mA g–1, while the capacity retention was 78.7%, and the Coulombic efficiency was stable at 99.3% after 200 cycles. The modification of the electrode structure provides guidance for the construction of high-efficiency anodes.
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高影响因子
ACS Catalysis
·
2019
·
IF 12.221
Xueping Qin,Lulu Zhang,Gui-Liang Xu,Shangqian Zhu,Qi Wang,Meng Gu,Xiaoyi Zhang,Chengjun Sun,Perla B. Balbuena,Khalil Amine,Minhua Shao
Improving the reaction kinetics of hydrogen evolution and oxidation reactions (HER/HOR) in alkaline media is critical to promote the development of alkaline fuel cells and electrolyzers. Here, we prepared Pd3Ru alloy nanocatalysts with Ru segregated on the surfaces, forming adatoms and clusters. This structure dramatically lowered the overpotential of Pd toward HER in 1 M KOH by 104 mV at 10 mA cm–2. The HER activity was even higher than that of Pt (6 mV improvement at 10 mA cm–2). Theoretical simulation results revealed that Ru adatoms/clusters on the surface could weaken the hydrogen-binding energy and promote the OH adsorption, consequently lowering the reaction barrier of the rate-determining step in HER. Our findings are of significance for clarifying the role of Ru in bimetallic catalysts and rational design of more active catalysts for HER/HOR.
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高影响因子
ACS Sensors
·
2024
·
IF 8.2
Kai Wang,Ke-Feng Gu,Jie Cao,Yu-Shun Yang,Hai-Liang Zhu,Jin-Hui Shang,Jie-Li Zhou
Copper ions, implicated in processes such as oxidative stress and inflammation, are believed to play a crucial role in cardiovascular disease, a prevalent and deadly disease. Despite this, current diagnostic methods fail to detect early stage cardiovascular disease or track copper ion accumulation, limiting our understanding of the disease’s progression. Therefore, the development of noninvasive techniques to image copper ions in cardiovascular disease is urgently needed to enhance diagnostic precision and therapeutic strategies. In this study, we report the successful synthesis and application of a copper ion-activated photoacoustic probe, CS-Cu, which exhibits high sensitivity and selectivity toward copper ions both in vitro and in vivo. CS-Cu was able to noninvasively monitor the changes in copper ion levels and differentiate between different mice based on copper ions in urine. Furthermore, the probe demonstrated good photoacoustic stability and exhibited no significant toxicity in the mice. These findings suggest that CS-Cu could be a promising tool for early detection and monitoring of Cu2+ levels in vivo and urine, providing a new perspective on the role of copper ions in cardiovascular disease.
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PubMed
高影响因子
TALANTA
·
2024
·
IF 5.6
Jiaying Geng,Zhongxi Huang,Qian Shen,Chenfeng Xu,Long Zhang,Cuilan Wei,Chan Fu,Weizhen An,Changmin Yu
With the emergence of numerous food safety problems, rapid and accurate detection of histamine in food spoilage remains a challenge. To this end, we developed a simple design and easy synthesis of fluorescein-based probe FCHO to achieve specific and rapid (<1 s) quantitative detection of histamine through “imine formation” reaction. Significant enhanced fluorescence signal in response to histamine enabled our probe with high sensitivity as low as 51 nM. Utilizing the visualized fluorescence color changes of the probe as histamine increasing, we combined it with paper-based test chip to construct a color-resolved and highly selective recognition system. In addition, our proposed probe has been successfully used to visually imaging histamine changes in fish samples. Finally, for the first time, we have proved it possesses reliable ability to directly in situ imaging the distribution of histamine in whole spoiled fish. Thus, our strategy will provide great potential for monitoring food spoilage.
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PubMed
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2016
·Vol. 21
·期 3
·715-724
·
IF 2.327
Zhang Kaiyue,Chen Si,Feng Yaqing,Shan Zhongqiang,Meng Shuxian
A novel polymer gel electrolyte was used to improve the performance and long-term stability in dye-sensitized solar cells (DSSCs). The polymer gel electrolyte (PGE) was prepared by mixing 5 wt% poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) and 2 % TiO 2 nanoparticles. The conductivity of PGE with P25 reached 9.98 × 10 −3 S/cm, which increased by 34.9 % compared with 7.40 × 10 −3 S/cm of PGE without P25, and the diffusion coefficient was also increased by 19.0 %. Different photoelectrodes were obtained by using three kinds of surfactants (cetylamine, octadecylamine, and P123) as pore-forming materials, and their morphologies were contrasted through scanning electron microscopy (SEM). The results showed that gel electrolyte can increase the short-circuit current density ( J
sc ) from 11.01 to 12.99 mA/cm 2 in DSSCs. Moreover, unlike the liquid electrolyte, the gel electrolyte is more conducive to the TiO 2 photoelectrodes with larger pores. In conclusion, the efficiency of DSSC with gel electrolyte and P123 as pore-forming material was 6.73 %, which was 12 % higher than the liquid electrolyte in the same test condition. In addition, the sealed gel electrolyte DSSCs showed better stability than did liquid electrolyte DSSCs during nearly 600 h.
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高影响因子
JOURNAL OF FOOD SCIENCE
·
2020
·Vol. 85
·期 4
·1285-1291
·
IF 2.479
Zi-Teng Wang,Ying Xue,Hong Sun,Zhe Zhang,Zhi-Jia Tang,Shuai-Bing Liu,Wei-Min Cai
Green tea is widely consumed as a beverage and/or dietary supplement worldwide, resulting in the difficulty to avoid the comedication with ticagrelor for acute coronary syndrome (ACS) patients receiving antiplatelet therapy. This study was designed to investigate the effect of the most abundant content in green tea, tea polyphenols on the oral and intravenous pharmacokinetics of ticagrelor in rats and its in vitro metabolism. Rats were orally treated with either saline or tea polyphenol extracts (TPEs) dissolved in saline once daily for 6 consecutive days. On day 6, after the last dose of saline or TPE, ticagrelor was given to the rats orally or intravenously. Plasma samples were collected for pharmacokinetic analysis. Human liver and intestinal microsomes were then used to investigate the inhibition by TPE, as well as its major constituents on the metabolism of ticagrelor to its two metabolites, AR-C124910XX and AR-C133913XX. Apparent kinetic constants and inhibition potency (IC 50 ) for each metabolic pathway of each compound were estimated. Oral study indicated that exposure of ticagrelor and AR-C124910XX was significantly decreased after TPE administration, while no significant differences were observed in pharmacokinetic parameters after intravenous administration of ticagrelor. TPE effectively inhibited the metabolism of ticagrelor in vitro , with epigallocatechin-3-gallate as the major constituent responsible for the observed inhibitory effects in human liver microsomes and intestinal microsomes (IC 50 = 4.23 ± 0.18 µM). Caution should be taken for ACS patients receiving ticagrelor therapy with daily drinking of green tea. Practical Application Potential interactions between tea polyphenols and ticagrelor were revealed for the first time. Results can provide suggestions for clinicians to optimize the dosing of ticagrelor while they are in the face of ACS patients receiving ticagrelor therapy, who also take green tea or its related products in their daily life.
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高影响因子
Journal of Innovative Optical Health Sciences
·
2024
·
IF 2.3
Yuxiang Gao,Chi Zhang,Lijun Zhu,Zhong Du,Rong Ma,Le Guo,Nuernisha Alifu,Xueliang Zhang
Triple-negative breast cancer (TNBC) is an aggressive and often fatal disease, especially since the brain metastasis of TNBC has been a particularly severe manifestation. However, brain metastasis in TNBC at early stages often lacks noticeable symptoms, making it challenging to detect. Near-infrared II (NIR-II) fluorescence microscopic imaging obtains long wavelength, which enables reduced scattering, high spatial resolution and minimal autofluorescence, it is also a favorable imaging method for tumor diagnosis. PbS@CdS quantum dots (QDs) are one of the popular NIR-II fluorescence nanoprobes for well brightness. In this study, NIR-II emissive PbS@CdS QDs were utilized and further encapsulated with thiol-terminated poly(ethylene oxide) (SH-PEG, MW = 5000) to form PbS@CdS@PEG QDs nanoparticles (NPs). The obtained PbS@CdS@PEG QDs NPs were then characterized and further studied in detail. The PbS@CdS@PEG QDs NPs had large absorption spectra, exhibited strong NIR-II fluorescence emission at approximately 1300 nm, and possessed good NIR-II fluorescence properties. Then, the mice model of early-stage brain metastases of TNBC was established, and the PbS@CdS@PEG QDs NPs were injected into the tumor-bearing mice for NIR-II fluorescence microscopic bioimaging. The brain vessels and tumors of the living mice were detected with high spatial resolution under the NIR-II fluorescence microscopic imaging system with irradiation of 808 nm laser. The tumor tissues were further restricted and prepared as thin slices. The NIR-II fluorescence signals were collected from the tumor slices with high spatial resolution and signal-to-background ratio (SBR). Thus, the PbS@CdS@PEG QDs NPs-assisted NIR-II fluorescence microscopic system can effectively achieve targeting brain metastases of TNBC imaging, offering a novel and promising approach for TNBC-specific diagnosis.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2019
·
IF 6.361
Zhengzhou Su,Chunmei Li,Jiaojun Tan,Ying Xue,Guoxian Zhang,Yumin Yang,Qiuyu Zhang
Oil-in-oil emulsions are ideal systems for water-sensitive reactions such as polymerizations and catalytic reactions , which has received extensive attention in recent years. The application of oil-in-oil emulsions has been developed slowly due to the limited types of surfactants and complicated synthesis process. Herein, we proposed a simple method to prepare poly(amide-thioether)-based surfactant for oil-in-oil emulsions via taking advantage of single-pot multicomponent and click characters of thiolactone chemistry. Using a combination of alkyl amine and acrylamide thiolactone, the aminolysis of thiolctone occurred first, generating thiol group in-situ, and then the generated thiol group would sequentially react with the double bonds of acrylamide to form polythioether in the presence of amine. The hydrophobicity of the surfactant could be effectively adjusted by the chain length of the alkyl amine and thus this polymer could serve as a promising surfactant for oil-in-oil emulsion. Notably, the emulsion types could be switched by changing the chain length of the alkyl amine. In addition, the effects of surfactant loading, volume ratio of oil phases, oil types on the size and stability of oil-in-oil emulsions were further investigated. It was demonstrated that the oil-in-oil emulsion stabilized by poly(amide-thioether)s kept stable after more than five months. Besides, we preliminarily explored the application of the oil-in-oil emulsion to prepare closed cell foam and porous particles via photo-initiated thiol-ene polymerization. It is believed that this super-stable oil-in-oil emulsion could offer more possibilities for highly potential water-sensitive systems.
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高影响因子
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
·
2019
·
IF 4.027
Jun Mo,Tingkai Chen,Hongyu Yang,Yan Guo,Qi Li,Yuting Qiao,Hongzhi Lin,Feng Feng,Wenyuan Liu,Yao Chen,Zongliang Liu,Haopeng Sun
Cholinesterase inhibitor plays an important role in the treatment of patients with Alzheimer’s disease (AD). Herein, we report the medicinal chemistry efforts leading to a new series of 1,3-dimethylbenzimidazolinone derivatives. Among the synthesised compounds, 15b and 15j showed submicromolar IC50 values (15b, eeAChE IC50 = 0.39 ± 0.11 µM; 15j, eqBChE IC50 = 0.16 ± 0.04 µM) towards acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Kinetic and molecular modelling studies revealed that 15b and 15j act in a competitive manner. 15b and 15j showed neuroprotective effect against H2O2-induced oxidative damage on PC12 cells. This effect was further supported by their antioxidant activity determined in a DPPH assay in vitro. Morris water maze test confirmed the memory amelioration effect of the two compounds in a scopolamine-induced mouse model. Moreover, the hepatotoxicity of 15b and 15j was lower than tacrine. In summary, these data suggest 15b and 15j are promising multifunctional agents against AD.
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2023
·Vol. 30
·期 6
·1-13
·
IF 2.8
Zhang Haoran,Xu Shuyan
With the advent of the 5G era, various thermal conductivity nanocomposites are being investigated to solve the heat accumulation on the surface of electronic devices. In this study, magnetic nanofiller ferroferric oxide-polydopamine-boron nitride nanosheets (Fe-PDA-BNNSs) are fabricated by mussel-inspired and coprecipitation methods with polydopamine (PDA) and ferroferric oxide (Fe 3 O 4 ). The aligned Fe-PDA-BNNSs/poly(vinyl alcohol) (PVA) composites with higher in-plane thermal conductivity and decent mechanical properties are prepared by applying a horizontal magnetic field. The in-plane thermal conductivity of the aligned composite at 30 wt% filler loading reaches 5.237 W/(m·K), which is 1.1 times and 20.5 times that of the unaligned composites and neat PVA. Moreover, the aligned composite maintains mechanical strength and obtains commendable thermal stability and heat dissipation capability, which can be applied to the thermal management of flexible electronic devices.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2014
·
IF 4.517
Jian Xu,Shaobo Sun,Qian Li,Ying Yue,Yingdong Li,Shijun Shao
A novel probe incorporating quaternized 4-pyridinium group into a BODIPY molecule was synthesized and studied for the selective detection of fluoride ions (F − ) in aqueous solution. The design was based on a fluoride-specific desilylation reaction and the “Turn-On” fluorescent response of probe 1 to F − was ascribed to the inhibition of photoinduced electron transfer (PET) process. The probe displayed many desired properties such as high specificity, appreciable solubility, desirable response time and low toxicity to mammalian cells. There was a good linearity between the fluorescence intensity and the concentrations of F − in the range of 0.1–1 mM with a detection limit of 0.02 mM. The sensing mechanism was confirmed by the NMR, electrospray ionization mass spectrum, optical spectroscopy and the mechanism of “Turn-On” fluorescent response was also determinated by a density functional theory (DFT) calculation using Gaussian 03 program. Moreover, the probe was successfully applied for the fluorescence imaging of F − in human epithelial lung cancer (A549) cells and alveolar type II (ATII) cells under physiological conditions.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2021
·
IF 8.742
Zhen Li,Xiaofeng Hao,Geng Cheng,Sheng Huang,Dongmei Han,Min Xiao,Shuanjin Wang,Yuezhong Meng
Polyhedral oligomeric silsesquioxane (POSS) has attracted increasing attention because of its organic/inorganic, nanosize, easily functional nature, especially in the applications of direct methanol fuel cells (DMFCs). In this work, we have successfully synthesized a novel bifunctional POSS ( Vi -POSS-SO 3 Na) with vinyl and sulfonic acid groups by thiol-ene click reaction. Vi -POSS-SO 3 Na was introduced into Nafion® matrix and cross-linked by in-situ simply thermal treatment. The implantation of the bifunctional POSS filler gives significant improvements in the performance of such proton exchange membranes (PEMs). The cross-linked hybrid membrane with 12 wt% of Vi -POSS-SO 3 Na ( X -Nafion@POSS-12) has a high proton conductivity (121 mS cm −1 ) at 80 °C, excellent dimensional stability and the lowest methanol permeability (5.4 × 10 −8 cm 2 s −1 ). The highest power density of the DMFCs was obtained by using the X -Nafion@POSS-12 as PEM in DMFC at 80 °C, and its value (34.93 mW cm −2 ) is twice higher than that of Nafion 212 membrane (14.90 mW cm −2 ). The novel in-situ fabrication method gives a simple and potential approach for the preparation of PEMs used in DMFCs.
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高影响因子
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