ACS Applied Materials & Interfaces
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2025
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IF 8.2
Cheng Dai,Qian Wang,Hun Huang,Ye Hu,Junlin Chen,Chuhan Lv,Hongbo Yu,Yun Li,Hua Dong
Rapid and efficient hemostasis of massive bleeding wounds remains a major challenge in clinical practice. Self-gelling powders are now emerging as the new-generation hemostatic materials due to their capability to form hydrogels via a self-gelling process and thus integrate the merits of powders and hydrogels. However, they still face several unsettled issues, such as complex components, tedious synthesis, and poor compatibility with hemostatic powders on sale. Herein, we propose a universal strategy to enhance the hemostatic, antibacterial, and wound healing performance of polysaccharide powders via a water-soluble assembly macromolecule (tannic acid-grafted carboxymethyl chitosan, CCTA). When CCTA is blended with polysaccharide hemostatic powders and exposed to blood, the abundant ortho-phenolic hydroxyl groups of CCTA can build a dense hydrogen bonding network with swollen powders (i.e., microgels), erythrocytes, and platelets, leading to the in situ formation of microgel assembly with excellent mechanical strength, tissue adhesion, and thus sealing performance. In addition, CCTA also endows hemostatic powders with good antibacterial activities. The as-formed porous microgel assembly facilitates cell migration and ingrowth, leading to accelerated wound healing and tissue repair in vivo. Three types of polysaccharide powders and three bleeding models (rat femoral artery, rabbit liver, pig liver, and spleen) are used to validate our strategy.
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产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Baoyue Zhang,Ruixue Wang,Fan Wan,Baijie Cheng,Xueying Wu,Peipei Xu,Xiaoyun Liu,Hongyao Xu,Shanyi Guang
Defect engineering modulates polarization loss by controlling common defects, including oxygen vacancies, impurity atom doping, and lattice defects, thereby improving the electromagnetic wave (EMW) absorption capability. Here, we designed a cobalt–nickel/hollow-Fe 3 O 4 (H-Fe 3 O 4 @CoNi) dual magnetic layer structure coated with nitrogen-doped carbon via a combined hydrothermal and pyrolysis. The dual magnetic architecture not only promotes magnetic loss but also introduces numerous heterogeneous interfaces. Simultaneously, nitrogen doping facilitates defect-induced dipole polarization, synergistically enhancing dielectric loss and impedance matching. By tuning the pyrolysis temperature, the electromagnetic parameters and EMW absorption performance of the composites were effectively optimized. The H-Fe 3 O 4 @CoNi@C-N-800 exhibited the best performance, with an effective absorption bandwidth (EAB) of 5.1 GHz and a minimum reflection loss (RL min ) of −55.6 dB. Density functional theory (DFT) calculations confirmed that electronic redistribution and charge transfer occurred at the N-doped carbon/Fe 3 O 4 –CoNi interface, validating that the enhanced dielectric loss stems from both dipole and interfacial polarization. Furthermore, CST simulation shows that the maximum radar cross section (RCS) value of H-Fe 3 O 4 @CoNi@C-N-800 can be reduced by 15.64 dB m 2 . These results suggest that this composite is a promising high-performance EMW absorbing material.
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DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Ziyue Chen,Qi Lin,Cheng Peng,Kunpeng Yu,Yanling Lin,Shuyi Weng,Lijun Li,Hui Ni,Feng Chen
Tea aroma is largely shaped by volatile compounds released from glycosidic aroma precursors. This study investigated the effects of two Aspergillus niger β-glucosidases, An-G3987 and An-G8816, on modulating the aroma profile of instant Oolong tea powder. Quantitative descriptive analysis (QDA), gas chromatography–mass spectrometry (GC–MS), and odor activity value (OAV) assessments revealed that An-G3987 significantly enhanced floral, sweet, and grassy aromas by releasing key volatile compounds such as benzyl alcohol, (Z)-3-hexen-1-ol, and 1-hexanol. In contrast, An-G8816 generated a broader spectrum of volatile compounds but had a less pronounced impact on overall aroma enhancement. Kinetic studies and molecular docking analyses demonstrated that An-G3987, compared to An-G8816, exhibited higher catalytic efficiency and stronger binding affinity for typical glycosidic aroma precursors, driven by hydrogen bonding networks (e.g., Arg107/Tyr254) and hydrophobic interactions (e.g., Pro428/Tyr497). These findings indicate that An-G3987 is better suited for targeted aroma intensification, while An-G8816 may be preferable for balanced flavor modulation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）