TALANTA
·
2019
·
IF 4.916
Lifen Cai,Xiangying Sun,Wei He,Ruolan Hu,Bin Liu,Jiangshan Shen
In this paper, a tetrahydro[5]helicene-based imide dye with thienyl group (THID) was studied on its solvatochromism and aggregation-induced emission (AIE) properties by dissolved in various organic solvents. The linear relationship between Stokes shift and aprotic solvent polarity parameter was well fitted with Lippert-Mataga model. Furthermore, Stokes shift also were positively correlated with the normalized molar electronic transition energy, suggested that THID exceptionally depends on solvent polarity for twisted intramolecular charge transfer. In addition, THID demonstrated typical AIE features when adding large amounts of water into good solvent. Meanwhile, it can function as intensity and wavelength-based fluorescence sensor for detecting low-level water content in water soluble solvents , even the low of detection was 0.014 vol% in ACN . Therefore, a simple and highly selective fluorescence analysis for glyceryl monostearate has been established on basis of its AIE property.
研究领域:
化学
·
材料科学
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DOI
高影响因子
FUEL
·
2024
·
IF 6.7
Zhonghai Liu,Kaili Wang,Yayun Pang,Chenglei Xiao,Xiaoping Wu,Jinliang Song,Tiejun Wang
One-pot dehydration-oligomerization of biomass-derived alcohols provides a promising strategy for the production of renewable jet fuels, but it is still a great challenge. In this study, the hierarchically porous plate-like HZSM-5 catalysts were constructed to catalyze dehydration-oligomerization of higher alcohols derived from upgrading of fermentation ethanol. It was observed that the P40(0.2) catalyst showed the best performance with the C 8 -C 16 products selectivity of 66.4%. Systematic investigations revealed that the outstanding performance of P40(0.2) originated mainly from the synergistic effect of the finely tuned acidity and the hierarchical porous plate-like structure. Notably, the good activity of P40(0.2) on dehydration-oligomerization of the actual oil phase from ethanol upgrading confirmed the great potential of practical applications for the synthesis of jet fuels from biomass-derived alcohols.
研究领域:
化学工程
·
催化
·
可再生能源
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2019
·
IF 6.361
Fei Li,Huanshun Yin,Yan Chen,Siyu Wang,Jingyan Li,Yuemei Zhang,Chunxiao Li,Shiyun Ai
DNA formylation (5-formylcytosine, 5fC) is a major epigenetic modification involved in alterations in the DNA double helix structure and protein identification. Due to the low amount in all mammalian tissues and cells, it is necessary to develop a rapid, sensitive and efficient method for detecting 5fC for further understanding the biological functions of 5fC. Thus, a novel PEC biosensor was constructed using P-g-C 3 N 4 -WS 2 nanocomposite as photoactive material. Firstly, AuNPs/P-g-C 3 N 4 -WS 2 /ITO electrode was prepared as substrate electrode. Secondly, the probe DNA and complementary DNA (containing 5fC base) was modified to the electrode surface based on the formation of Au-S bonds between AuNPs and thiol group on the probe DNA and hybridization, respectively. Finally, the amino functionalized MnO 2 nanoflowers were further modified to the electrode surface by covalent interaction between the aldehyde group on the 5fC and the amino group on MnO 2 nanoflowers. The sensitive and specific detection of 5fC can be achieved by oxidizing ascorbic acid with MnO 2 nanoflowers and quenching the photoactivity of P-g-C 3 N 4 -WS 2 nanocomposite. The sensor has a detection range of 0.01–200 nM and a detection limit of 3.8 pM. Moreover, this sensor has excellent detection specificity, stability and reproducibility.
研究领域:
生物化学
·
分析化学
·
表观遗传学
·
纳米技术
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DOI
PubMed
高影响因子
Sensors & Diagnostics
·
2023
·Vol. 2
·期 2
·427-437
·
IF 0
Xiangfei Zheng,Dongmiao Qin,Shenglan Hu,Weiming Mo,Biyang Deng
Tin oxide nanoflowers (SnO2NFs) are used as both an electrochemiluminescent (ECL) signal generator and a carrier of nanomaterials due to the advantages of excellent electrical conductivity, large specific surface area, and good optical properties. AuNPs/PEI-SnO2NFs provide a larger binding site for the immobilization of secondary antibodies (CA12-5-Ab2). The synthesized Ag@ZnONS composite with a large specific surface area and good biocompatibility was applied to immobilize more primary antibodies (CA12-5-Ab1), which further enhanced the ECL signal and obviously improved the sensitivity and selectivity of the immunosensor. A novel signal amplification ECL immunosensor for detecting carbohydrate antigen 12-5 (CA12-5) was fabricated with AuNPs/PEI-SnO2NFs as a signal probe and Ag@ZnONSs as the sensing matrix. The ECL intensity was linearly related to the logarithm of the CA12-5 concentration in the range from 1 × 10−5 to 50 ng mL−1 under optimized conditions. The limit of detection was 2.6 fg mL−1 (S/N = 3). The assay had good operational stability, specificity, and high sensitivity. The study was applied to analyze the CA12-5 level in human serum with satisfactory results, which could be applied in clinical immunoassays.
研究领域:
分析化学
·
生物传感器
·
纳米技术
·
临床诊断
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DOI
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Renna Li,Tianshan Xue,Zhe Li,Qiang Wang
Hydrophobic zeolites have been considered as one of the most promising adsorbents for capturing volatile organic compounds (VOCs). In this contribution, hierarchically structured ZSM-5/SBA-15 composites with different morphologies including platelet, hexagonal prism, long-hexagonal prism, and long-rod were prepared. All materials were characterized using XRD, SEM, and TEM-EDX, which confirmed that the high dispersion of two zeolites within the composites. Due to the presence of intracrystalline mesopores that could shorten the diffusion pathway of toluene, the composites resulted in increased effective diffusion and higher adsorption capacity. The composites also possess higher hydrophobicity, leading to much better toluene adsorption performance under humid conditions. The water contact angle of ZSM-5 could be increased from 15.6° to 44.9° by forming well dispersed zeolite composites. The 29 Si MAS NMR results confirmed that the composites possess higher amount of Q 4 groups (75.3%–80.1%), which is the intrinsic reason for higher hydrophobicity. Notably, ZSM-5/SBA-15-hexagonal prism resulted in the best adsorption performance and cycling stability when compared with pure ZSM-5, the breakthrough time was increased from 20.8 to 49.4 min under dry conditions and from 5.9 to 27.3 min in the presence of 50% relative humidity. This work represents an important scheme for making hydrophobic zeolite-based VOCs adsorbents with also improved toluene diffusion properties due to the unique hierarchical porous structure.
研究领域:
材料科学
·
环境工程
·
化学工程
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DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2013
·Vol. 36
·期 7
·1283-1290
·
IF 2.591
Shaolei Yang,Chunyan Chen,Zhihong Yan,Qingyun Cai,Shouzhuo Yao
Metal-organic frameworks, a new class of materials with high surface area and great porosity, have been widely applied in gas sorption. It is generally known that metal-organic framework 5 cannot be applied in aqueous phase since it is water sensitive. However, this work reveals that the derived material of metal-organic framework 5 is a good SPE sorbent that can be applied to aqueous phases. Metal-organic framework 5 was prepared and used as a SPE sorbent for the determination of polycyclic aromatic hydrocarbons in environmental matrices coupling with HPLC. The water treatment induced changes in the properties were investigated in detail. Even though metal-organic framework 5 is conversed to a second phase after water treatment, it still shows high extraction ability. Under the optimized experimental conditions, good sensitivity levels were achieved with low LODs ranging from 0.4 to 4.0 ng L −1 and a linearity of 0.004–20 μg L −1 ( R 2 > 0.996) for the investigated polycyclic aromatic hydrocarbons. The method has been validated in the analysis of real water samples with recoveries in the range of 80.2–120.2% and RSDs in the range of 0.5–11.7%.
研究领域:
分析化学
·
环境科学
·
材料科学
·
污染物检测
·
样品前处理
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DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2020
·
IF 4.049
Ruiyu Liang,Yuling Hu,Gongke Li
The monodisperse pillar[5]arene-based polymeric sub-microsphere was prepared by polycondensation of hydroxylated pillar[5]arene and cyanuric chloride through a one-pot reaction in mild condition. The preparation was realized by a simple two-step temperature-programmed process without heating operation. The obtained polymeric sub-microsphere exhibited monodisperse and regular spherical structure with uniform particle size distribution of 220–320 nm accounting for 94%. The prominent adsorption capacity of the polymeric sub-microsphere for antioxidants was demonstrated and attributed to the synergistic effect of the cladding interaction with the π-electron rich cavity and hydrophilic interaction with terminal hydroxyl on pillar[5]arene. Then the pillar[5]arene sub-microsphere was packed into a micro-column to realize effective on-line enrichment of antioxidants coupling with high-performance liquid chromatography (HPLC). The flow rate of extraction and desorption solvent, clean-up and desorption volume were assessed to optimize the method. The method showed wide linear ranges with R 2 greater than 0.9926, low limits of detection (0.030–0.20 μg/L) and limits of quantification (0.10–0.67 μg/L). The developed method was successfully applied to determine trace antioxidants in the migration of food contact materials with simulated solution, which demonstrated the promising potential of this method for practical analysis. Furthermore, the migration behavior of antioxidants from food packaging materials into different food matrix was also investigated.
研究领域:
分析化学
·
食品科学
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DOI
PubMed
高影响因子
Arabian Journal of Chemistry
·
2022
·
IF 6.212
Zizhen Zhao,Chen Fu,Yuping Zhang,Yingying Zhang,Xiaoxi Yang,Ailing Fu
The incidence of HCC continues to increase rapidly in recent years. the principle of developing anti-HCC drugs is to specifically kill tumor cells, without affecting the function of normal cells. Here we synthesized a novel protonic compound bis(5-amino-1,10-phenanthroline) (P-BAP), and the antitumor activity was explored in vitro and in vivo . The results showed that P-BAP could selectively inhibit the proliferation of tumor cells, and induce HCC apoptosis. In HCC-bearing mice, P-BAP could effectively retard the tumor growth, even completely eliminate the tumors at the dose of 5 mg/kg, and meanwhile P-BAP had no significant effect on mouse body weight. Mechanism analysis revealed that P-BAP could down-regulate the protein expressions of pleomorphic adenoma gene like-2 (PLAGL2), HIF-1α and β-catenin, and up-regulate the levels of pro-apoptotic protein BAX and BNIP3. In addition, P-BAP could reduce mitochondrial respiratory chain complex activities, leading to insufficient ATP production. The study provides a new approach for designing selective antitumor drugs, and suggests that P-BAP would be a potential candidate for HCC therapy.
研究领域:
肿瘤学
·
药理学
·
分子生物学
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DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2022
·
IF 6.633
Hongjun Zang,Yimo Feng,Jing Lou,Kai Wang,Changchun Wu,Zhipeng Liu,Xi Zhu
Ionic liquids have shown good catalytic performance and been widely used in the biomass conversion process due to their unique properties, including environmental friendship, low toxicity, and simple preparation. In this work, a series of novel piperidinium-based ionic liquids were synthesized under mild conditions via a simple protonation reaction or nucleophilic substitution reaction. Among them, 4,4′-(propane-1,3-diyl)bis(1-(carboxymethyl)piperidin-1-ium) chloride ([PDCMPi]Cl) displayed the best catalytic performance. The highest yield (42.81 %) of 3A5AF from NAG was obtained after reacting in N-methyl-pyrrolidone (NMP) in the presence of piperidinium-based ionic liquids at 180 °C for 20 min under normal atmospheric conditions. Additionally, ionic liquid [PDCMPi]Cl showed good catalytic activity in six repeated catalytic runs. Meanwhile, a possible reaction pathway was also proposed on the basis of the results of NMR spectra.
研究领域:
催化化学
·
绿色化学
·
生物质能源
·
有机合成
·
离子液体化学
✓ 已验证
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Jin Wang,Lin Zhou,Jiali Bei,Mengyuan Xie,Xiting Zhu,Tingting Chen,Xiaomei Wang,Yukou Du,Yong Yao
In this work, the ultrasensitive photoelectrochemical (PEC) sensor for the detection of bovine hemoglobin (BHb) was developed based on water-soluble pillar[5]arenes (WP5) functionalized gold nanoparticles (Au NPs) and bismuth oxybromide (BiOBr) nanoflowers (Au@WP5/BiOBr). The photoelectrical signal of dopamine (DA) was decreased after adding the different concentrations of BHb due to the formation of hydrogen bond between the COOH groups of BHb molecules and the NH 2 group of DA, which could achieve the indirect detection of BHb. Benefiting from the photo-generated electron-holes of BiOBr nanoflowers, the localized surface plasmon resonance (LSPR) effect of Au NPs, the host–guest interaction of WP5 between and DA, the PEC sensor showed a specifically recognize toward BHb with a wide detection range of 1.0 × 10 −11 –1.0 × 10 −1 mg/mL and a detection limit of 4.2 × 10 −12 mg/mL (S/N = 3). Additionally, the proposed PEC sensor also displayed good stability, remarkable selectivity and provided a promising strategy of design pillar[5]arenes functionalized photoelectric activity nanomaterials for PEC sensing application.
研究领域:
生物传感器
·
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
Carbon Letters
·
2026
·
IF 6.2
Liang Yuwei,Huang Yufan,Hu Chunling,Cai Jinyu,Cao Yifan,Meng Guihua,Wu Jianning,Li Qi,Liu Zhiyong
Designing catalysts with suitable valence conduction band positions to generate reactive oxygen species (ROS) with moderate redox capacity is to achieve efficient photocatalytic biomass-selective value-added oxidation. This protocol addresses the issue by tuning material structural defects, altering the surface electronic structure, and ultimately enhancing the raw material’s performance. Here, an appropriate amount of one - dimensional nanorods α -MnO 2 adjusted material structural defects, increased the adsorbed oxygen (O ads )/lattice oxygen (O latt ) and Mn 3+ ratios, and served as an electron transport conduit, facilitating O₂ activation to generate ROS. The Cd 1.7 In 2 S 4.7 solid solution enables the optimal valence band position by adjusting the Cd 2+ : In 3+ ratio, thus selectively oxidizing 5-hydroxymethylfurfural (HMF) to 2,5-dicarbonylfuran (DFF). In situ XPS revealed that photogenerated electrons in Cd 1.7 In 2 S 4.7 quickly transferred to the conduction band of α -MnO 2 , and photogenerated holes from α -MnO 2 moved to the valence band of Cd 1.7 In 2 S 4.7 . This significantly enhanced the separation and transfer efficiency of photogenerated carriers at the interface. The optimal sample achieved 56% conversion of HMF and 72% selectivity of DFF under simulated sunlight. This protocol provides a new approach for the establishment of electron transport channel structures based on α -MnO 2 constructs and value-added biomass photocatalytic conversion under simulated sunlight.
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产品关联
DOI
高影响因子
JOURNAL OF POROUS MATERIALS
·
2024
·
IF 2.5
Zhang Yanting
Both seed solution and Cetyltrimethylammonium bromide(CTAB) serve as common template agents in the synthesis of hierarchical ZSM-5 zeolites. However, their specific roles in the synthesis process have not been clearly understood. In this study, hierarchical ZSM-5 zeolites were successfully synthesized using a 1.5% mass fraction (relative to the silicon source) seed solution in combination with varying amounts of CTAB. The physical and chemical properties of the hierarchical ZSM-5 zeolites were characterized using X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), low-temperature N 2 adsorption-desorption, scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermogravimetric analysis (TG), ammonia temperature-programmed desorption (NH 3 -TPD), pyridine-IR, and 2,4,6-collidine-IR. The investigation revealed that the CTAB content significantly influenced the synthesis of hierarchical ZSM-5 zeolites, with CTAB contributing to framework filling, charge balancing, and acting as a mesoporous template during the synthesis process, while the seed solution primarily served as a structure-directing agent. Moreover, utilizing the conversion of C8 aromatic hydrocarbons as a probe reaction, it was demonstrated that ZSM-5 zeolites synthesized with the co-assistance of seeds and CTAB exhibited enhanced conversion for ethylbenzene and m-xylene compared to samples synthesized exclusively with a seed solution.
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）