POLYMER
·
2021
·
IF 4.43
Jia-Wei Li,Miao Chen,Jie-Mei Zhou,Cai-Yuan Pan,Wen-Jian Zhang,Chun-Yan Hong
Polymerization-induced self-assembly (PISA) is an efficient and robust strategy to fabricate polymeric nano-objects. PISA enables us to prepare polymeric nano-objects in situ during the course of polymerization in concentrated solution (up to 50% w/w), making industrial production of polymeric assemblies in large-scale possible. In this work, reversible addition-fragmentation chain transfer (RAFT) dispersion copolymerization of styrene (St) and N-methacryloxysuccinimide (NMAS) was conducted with poly(2-hydroxyethyl acrylate) (PHEA) as a macro-chain transfer agent (macro-CTA) in methanol. Compared with the PHEA-mediated alcoholic dispersion polymerization of St, RAFT dispersion copolymerization of St and NMAS promoted morphology transition of nano-objects to form higher order morphologies (such as worms and vesicles). Moreover, the introduction of NMAS units into the solvophobic blocks provided functional handles for post-PISA modification of the resultant nano-objects via the active ester-amine reaction. The reaction of 1,6-hexanediamine with NMAS units in P(St- co -NMAS) blocks was conducted to afford cross-linked nano-objects with robust structural stability.
研究领域:
高分子化学
·
材料科学
✓ 已验证
DOI
高影响因子
CHINESE JOURNAL OF CATALYSIS
·
2021
·
IF 8.271
Juan Xiao,Junwei Chen,Zuqiao Ou,Junhang Lai,Tongwen Yu,Yi Wang
Herein, the application of a N-doped graphitic-carbon-coated iron nitride composite dispersed in a N-doped carbon framework (Fe 3 N@NG/NC) is investigated as a heterogeneous electro-Fenton (HE-EF) catalyst for the efficient removal of organics. The simultaneous carbonization and ammonia etching of iron-based metal organic framework (Fe-MOF) materials yielded well-dispersed N-doped carbon-coated Fe 3 N nanoparticles with a diameter of ~70 nm. The Fe 3 N and pyridinic N endowed the composite with high HE-EF activity for decomposing the electrogenerated H 2 O 2 to • OH. The Fe 3 N@NG/NC exhibited outstanding HE-EF performance in removing various organic pollutants with low iron leaching. A removal rate of 97–100% could be obtained for rhodamine B (RhB), dimethyl phthalate , methylene blue , and orange II in 120 min at a pH of 5.0. When the solution pH was set to 3.0, 5.0, 7.0, and 9.0, the removal rate of RhB reached 100%, 96%, 92%, and 81%, respectively, in 60 min at an optimum voltage of 0.0 V ( vs. reversible hydrogen electrode (RHE)). Moreover, the concentration of leached iron was expected to be below 0.03 mg/L in a wide pH range of 3.0–9.0. In addition, the RhB removal efficiency remained as high as 90% after six cycles in the reusability experiments. This work highlights the MOF-derived Fe 3 N composite as an efficient HE-EF catalyst and the corresponding catalytic mechanism, which facilitates its application in wastewater treatment .
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
Journal of Biomedical Nanotechnology
·
2023
·Vol. 19
·期 8
·1495-1502
·
IF 2.9
Pan Yiting,Bai Haihong,Zhang Guocheng,Liu Wei,Wu Yanqi,Chen Hui,Tian Ying,Yang Zhenqi,Feng Duan,Liu Jiaqi,Wu Dan
N-Glycosylation is one of the most common and important protein posttranslational modifications. Structural aberrations of the N-glycans branching from glycoproteins are closely related to various disease occurrences and progressions. Therefore, global systematic identification of disease-related
N-glycans not only largely facilitates the understanding of their cellular functions but also promotes the development of new diagnostic and therapeutic biomarkers. However, N-glycans are low in abundance and hydrophilic, thereby hindering high-throughput, and large-scale N-glycan analysis
and N-glycoproteome research. Here, a zwitterion-functionalized polymer brush-grafted silica hybrid hydrophilic material (poly-SBMA-S) was fabricated by in situ growth of polymeric [2-(methacryloyloxy)ethyl]dimethyl(3-sulfopropyl)ammonium hydroxide (SBMA) chains on porous silica particles
through a surface-initiated atom transfer radical polymerization technique, and it was used as a new stationary phase for highly selective N-glycan enrichment. Human plasma demonstrated 64 N-glycans due to the densely packed polyzwitterion chains and the significantly increased coverage of
hydrophilic binding sites, demonstrating the high potential of the new hydrophilic matrix in the profiling and analysis of N-glycans and other hydrophilic targets.
研究领域:
生物化学
·
蛋白质组学
·
医学诊断
✓ 已验证
DOI
高影响因子
MATERIALS SCIENCE FORUM
·
2017
·
IF 0
Li Peng,Jia Ni Huan,Jing Hua Gong,Jing Hong Ma
Smart hydrogel is a kind of new soft and wet material which can be responsive to external stimuli. Hydrogel fiber owning one dimension size can significantly improve response speed and be easily formed into higher-order assemblies. N-isopropylacrylamide/calcium alginate (NIPA/Ca-alginate) as-spun fiber was generated via microfluidic spinning. Then PNIPA/Ca-alginate hydrogel fiber was prepared through off-chip free radical polymerization of NIPA in the presence of Ca-alginate. The structure and morphology of the hydrogel fiber were characterized by FTIR and SEM. The swelling property and temperature-/pH-response behaviors were also investigated. The PNIPA/Ca-alginate hydrogel fiber had a 3D network porous structure. The thinner the hydrogel fiber, the faster the swelling speed was. Meanwhile, the hydrogel fiber exhibited temperature and pH response.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
Journal of Materials Chemistry B
·
2013
·Vol. 1
·期 15
·2072-2077
·
IF 0
Jingjie Cui,Yakun Ge,Shaowei Chen,Hongshi Zhao,Hong Liu,Zhen Huang,Huaidong Jiang,Jing Chen
Nano-p–n junction heterostructures based on TiO2 nanobelts with enhanced (001) facets were produced by assembling p-type semiconductor NiO nanoparticles on n-type surface-coarsened TiO2 nanobelt surfaces. The heterostructures were then used as the sensing electrode for the electrochemical detection of anticancer drugs O6-benzylguanine (O6BG) and lung cancer cells. O6BG exhibited an irreversible diffusion-controlled electrochemical process with an oxidation peak clearly identified at +0.78 V. For lung cancer cells one oxidation peak was found at +1.1 V and two reduction peaks at +0.30, and +0.90 V. These voltammetric features disappeared when O6BG was added to the lung cancer cells, which was ascribed to the structural changes of the cell membranes caused by the anticancer drug. These results suggested that nano-p–n junction heterostructures based on TiO2 nanobelts might serve as promising candidates for biosensing applications of anticancer drugs and tumor cells that will be of significance in diagnostic medicine, cancer diagnosis and molecular biology research.
研究领域:
生物传感
·
癌症诊断
·
分子生物学
✓ 已验证
DOI
PubMed
NEW JOURNAL OF CHEMISTRY
·
2019
·Vol. 43
·期 35
·13967-13978
·
IF 3.069
Qiang Ning,Huaike Zhang,Yurong He,Zhiqiang Chen,Suyao Liu,Jie Ren
Small Pt particles (about 1.2 nm) were highly dispersed on ZSM-22 zeolites via a strong electrostatic adsorption (SEA) method and exhibited a promotion effect on the catalytic performance in n-dodecane isomerization in comparison with the conventional catalyst. Several promoters (Ce, La, and Re) were introduced to further improve the aggregation resistance of the small Pt particles. A series of characterization including H2-TPR, XPS and STEM as well as DFT calculations provided solid evidence that the strong interaction between Pt and promoter species not only effectively hinders the Pt aggregation but also alters the electronic state of the Pt sites. Moreover, Ce and La promoters also lead to a slightly improved amount of B acid sites determined by Py-FTIR. Thus, improved activity and selectivity were achieved on a Ce-modified catalyst due to the better balanced bifunctionality between the slightly increased acidity of zeolites and electron-deficiency of Pt. The electron-rich Pt sites are responsible for the significant increase of CH4 selectivity and the decrease of total isomer selectivity in n-dodecane isomerization. In addition, a high-temperature reduction test revealed the higher isomerization activity and selectivity (about 10% higher than the unmodified catalyst) of the Ce-modified catalyst owing to the strong bond of Pt–O–Ce, further confirming the positive effect of the Ce promoter on the sintering resistance of small Pt particles.
研究领域:
催化化学
·
材料科学
·
计算化学
✓ 已验证
DOI
高影响因子
Applied Catalysis O: Open
·
2024
·
IF 0
Yongsi Jiao,Cunjun Li,Yanqi Xu,Limei He,Linjiang Wang
Photodegradation of indigo carmine (IC) in wastewater has received much attention in recent decades. However, the current photocatalysts used for IC photodegradation suffer from an unsatisfactory efficiency due to low yield of reactive species. Herein, a P-modified biochar/g-C 3 N 4 (P-BC/CN) photocatalyst was fabricated by mechanochemical method using P-modified biochar and g-C 3 N 4 as precursors. It is discovered that P N bonds were constructed between P-modified biochar and g-C 3 N 4 , and these bonds served as the active sites to promote the generation of •O 2 − during the photodegradation process. The biochar component in P-BC/CN composite is conducive to transfer the photogenerated carriers, thereby avoiding their recombination. The photodegradation experiment showed that the P-BC/CN composite exhibits an impressive photodegradation performance towards IC ( C 0 = 50 mg/L) with a photodegradation rate of 95.3% in 120 min. This work provides a green and efficient method to design biochar-based photocatalyst with P N active sites for advanced wastewater purification.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
DOI
ELECTROCHIMICA ACTA
·
2022
·
IF 7.336
Song-Yi Liao,Shuai-Fu Cui,Yue-Zhu Li,Wei-Xiang Cheng,Xing-Wen Huang,Jing Zhang,Ting-Ting Cui,Xu-Gang Shu,Yong-Gang Min
In this work, the wrinkled, flexible, and layered nitrogen-doped Ti 3 C 2 T x (shorten as N-MXene) is synthesized by using cyanamide as N-dopants. The changeable (002) plane spacing and the attached functional groups of N-MXene are detected by XRD and XPS analyses in details, respectively. The microscopic morphology of N-MXene is characterized by SEM and TEM, which demonstrates its wrinkled and flexible characteristics. When the wrinkled N-MXene being added into the LiNi 0.8 Co 0.1 Mn 0.1 O 2 (NCM811) as conductive additive, the attained electrodes obtain enhanced electrochemical performances at the appropriate weight ratio (namely 2.5-N-MXene with 2.5 wt.%). The 2.5-N-MXene delivers “extra” capacity of 226.9 mAh/g at 0.1 C (20 mA/g) current density. The “extra” capacity is assigned to Li ions intercalation/extraction from the wrinkled/flexible/layered N-MXene. Moreover, based on the analyses of CV and dQ/dV curves, the wrinkled/flexible N-MXene additive could effectively inhibit the phase transition of M↔H2 of NCM811 and alleviate the volume change of the particles in the circulation. From DFT simulation, the N-MXene is more capable of preventing Ni/Co/Mn from dissolving and migrating to the negative electrode to form dendrites through adsorption. Therefore, the N-MXene should be a very competitive conductive agent to improve the mechanical and electrochemical properties of high nickel cathode materials.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2015
·Vol. 15
·期 6
·4608-4618
·
IF 1.556
Cui Qinmin,Zhu Shudi,Yan Yingjie,Ye Quanlin,Ziener Ulrich,Cao Zhihai
In the present study, superparamagnetic Fe3O4/poly(N-isopropyl acrylamide) nanocomposites were synthesized by one-step inverse miniemulsion copolymerization of N-isopropyl acrylamide and N,N'-methylene diacrylamide. The loading of Fe3O4 nanoparticles
in the nanocomposites was 27 wt%, and the saturation moment of the nanocomposites was 12.4 emu · g−1. Fe3O4 nanoparticles were prepared through a coprecipitation method. The amount of stabilizer (poly(acrylic acid)) significantly influenced the
size and size distribution of the Fe3O4 nanoparticles, and, therefore, their magnetic properties. Superparamagnetism of the Fe3O4 nanoparticles was preserved in the nanocomposites. The effects of synthetic parameters on the particle properties, namely
surfactant loading, concentration of ferrofluid, type of lipophobe and initiator, and amount of cross-linker were investigated. Nanocomposites of Fe3O4/poly(N-isopropyl acrylamide) displayed a guava-like morphology, which they could retain after being redispersed
in polar solvents.
研究领域:
材料科学
·
纳米技术
·
化学工程
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry B
·
2021
·Vol. 10
·期 5
·717-727
·
IF 6.331
Zhiyu Li,Yichun Gao,Huinan Zhang,Fang Lan,Yao Wu
Alterations in plasma membrane glycoproteins (PMGs) have been identified as a hallmark of cancer. The comparison and identification of differential PMGs is significant for finding new markers and understanding pathological processes. However, the research on PMGs is often constrained by the low abundance and the disturbance of abundant endogenous biomolecules during direct analysis. Here, we report a bottom-up strategy to enrich the PMGs of breast cancer cells using hydrophilic magnetic covalent triazine frameworks (CTFs). A total of 972 N-glycopeptides and 1006 N-glycosites belonging to 526 N-glycoproteins were enriched in MCF-10A plasma membrane tryptic digest by magnetic CTFs. And 680 N-glycopeptides and 806 N-glycosites belonging to 443 N-glycoproteins were enriched in SK-BR-3 plasma membrane tryptic digest. Furthermore, comparative analysis was performed based on gene ontology to verify breast cancer biomarkers (SUSD2 and ALCAM) and differential PMGs’ function. This strategy which systematically integrates efficient enrichment of differential PMGs and in-depth comparative analysis has great potential for helping illuminate the atlas of breast cancer PMGs and the causes of tumor metastasis.
研究领域:
癌症研究
·
蛋白质组学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
ChemSusChem
·
2020
·Vol. 13
·期 16
·4151-4158
·
IF 7.962
Huai Liu,Ning Ding,Junnan Wei,Xing Tang,Xianhai Zeng,Yong Sun,Tingzhou Lei,Huayu Fang,Tianyuan Li,Lu Lin
Graphical No base needed : N-doped carbon-supported CoCu bimetallic catalyst with enhanced O 2 activation ability and basicity is demonstrated as an effective catalyst for the oxidative esterification of 5-hydroxymethylfurfural. The introduction of Cu significantly enhances the catalytic activity, resulting in a high furan-2,5-dimethylcarboxylate yield and an impressive formation rate, paving the way for the efficient and green synthesis of sustainable bio-based polymer monomers. The direct fabrication of furan-2,5-dimethylcarboxylate (FDMC), a promising renewable monomer, from biomass-derived 5-hydroxymethylfurfural (HMF) is a cutting-edge process. In this contribution, an elaborately designed N-doped carbon-supported CoCu bimetallic catalyst (Co x Cu y -NC; x / y= 9:1, 7:3, 4:6, which represents the designed molar ratio of Co and Cu in the catalyst), which could offer a desirable FDMC yield of 95 % under mild and base-free conditions (Co 7 Cu 3 -NC, 2 bar O 2 , 80 °C, 4 h) is described for the oxidative esterification of HMF. Notably, an FDMC formation rate of 6.1 mol FDMC mol Co −1 h −1 was achieved over Co 7 Cu 3 -NC, which represents the highest catalytic efficiency so far among Co-based catalytic systems. It has been demonstrated that Cu-doping in Co 7 Cu 3 -NC catalyst brings about more active sites (Co-N x species) with stronger molecular oxygen activation ability. The increase of surface N content of Co 7 Cu 3 -NC also improves basicity of the catalyst, which favors the hydrogen abstraction process during the HMF oxidative esterification reaction. These findings may pave an efficient and green way for the synthesis of sustainable bio-based polymer monomers.
研究领域:
催化化学
·
生物质转化
·
绿色化学
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2015
·Vol. 19
·期 12
·3613-3620
·
IF 2.446
Yang Suling,Li Gang,Wang Guifang,Deng Dehua,Qu Lingbo
A novel electrochemical sensor based on Fe 2 O 3 nanoparticles supported on N-doped graphene (Fe 2 O 3 NPs/N–GR) has been fabricated for electrocatalytic oxidation and detection of L-cysteine. The Fe 2 O 3 NPs/N–GR was characterized by scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy (XPS), and electrochemical methods. The electrochemical behavior of L-cysteine at Fe 2 O 3 NPs/N–GR was investigated by voltammetry. The Fe 2 O 3 NPs/N–GR showed a very efficient electrocatalytic activity for the oxidation of L-cysteine in 0.1 M phosphate buffer solution (PBS, pH 7.0). The oxidation peak currents increased dramatically at Fe 2 O 3 NPs/N–GR-modified electrode. The potential utility of the sensor was demonstrated by applying it to the analytical determination of L-cysteine. Experimental results showed that the electrocatalytic current increased linearly with L-cysteine concentration in the range of 0.2–400 μM with a lowest detectable concentration of 0.1 μM.
研究领域:
分析化学
·
生物医学工程
·
材料科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）