JOURNAL OF THERMAL SPRAY TECHNOLOGY
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2025
·
IF 3.3
Zhang Jian,Chen Hongxuan,Pang Xiaotong,Liu Shilong,Misra R. D. K.,Sun Junhao
Currently, surface coatings on agricultural machinery are crucial for extending service life. However, achieving coating strength and toughness remains a challenge. In this paper, two types of high-hardness iron-based coatings, referred as S1 and S2, were prepared by modulating the Mo/V ratio in the Fe-C-V-Mo-B system, and their microstructural evolution and property changes were investigated. The results show that the S1 coating primarily consist of martensitic matrix, spherical VC, blocky Mo 2 B, and a small amount of skeleton-like Mo 2 B. In contrast, the S2 coating consist of martensitic matrix, petal-like VC, and skeleton-like Mo 2 B. Compared with S1, the VC volume fraction in S2 increases by 6.5%, and the Mo 2 B volume fraction increases by 16.3%. The average microhardness of S1 and S2 coatings are 737 HV 0.5 and 954 HV 0.5 , respectively, indicating that the S2 coating exhibits a 22.7% higher microhardness compared with S1. The average friction coefficients of S1 and S2 coatings are 0.434 and 0.398, respectively. Furthermore, the wear loss of S2 coating is approximately half that of S1. The fracture toughness of S1 and S2 coatings are 51.9 MPa·m 1/2 and 51.7MPa·m 1/2 , respectively. Fracture analysis reveals that the skeleton-like eutectic structure in S2 can deflect cracks generated by impact, increase the length of propagation path, and improve the toughness of coating. It allows S2 coating to achieve high hardness and wear resistance, while maintaining toughness comparable to S1 coating. This study provides a theoretical basis for the design and development of iron-based coatings with high hardness, high abrasion resistance, and impact resistance for agricultural machinery.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
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2024
·
IF 3.5
Cao Kai,Shi Yunfeng,Liu Xiaowu,Wang Chengyue,Zhang Liang,Wang Xugang,Wu Bin,Lv Zhong
Prostate cancer (PCa) is the most common malignant tumor of male genitourinary system, ranking second among all male malignant tumors and showing a trend toward younger age. However, for metastatic prostate cancer, commonly used androgen deprivation therapy combined with docetaxel chemotherapy or neoendocrine therapy is prone to complications (incontinence, erectile dysfunction, and rectal damage), resulting in reduced quality of life or serious side effects for patients. Therefore, the designed GO-DAA-Ce6 nanoparticles were constructed to couple graphene oxide and Ce6 via diacylhydrazine adipate (DAA) as a bridge. The combination therapy of PTT and PDT is made possible by the outstanding photothermal conversion ability of GO and the high singlet oxygen generation of Ce6. GO-DAA-Ce6 demonstrated low toxicity and great biocompatibility in cytotoxicity and hemolysis assays. According to the outcomes of in vitro anti-tumor tests, GO-DAA-Ce6 greatly outperformed the photothermal and photodynamic efficacy of GO alone and Ce6 alone in terms of tumor suppression rates. The findings of the anticancer mechanism study point to the possibility that GO-DAA-Ce6 may cause cancer cells to undergo apoptosis and necrosis by initially damaging suborganelles such mitochondria. The straightforward design of the photothermal and photodynamic collaboration platform kills prostate cancer effectively and offers a general method for the treatment of various conditions including inflammation and skin infections.
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Journal of Inorganic and Organometallic Polymers and Materials
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2025
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IF 4.9
Jing Zhijie,Zhang Xiaorui,Jin Yimin,Wang Jianhua,Chai Chaofan,Bian Wei
Using multifunctional nanocomposites for multiple therapeutic approaches has emerged as an innovative cancer treatment strategy. Chemotherapy and chemodynamic therapy (CDT) have many benefits for cancer therapy, in which have great significance to develop nanocomposites that enable chemotherapy/CDT combined treatment. Herein, in situ co-precipitation method was used to load curcumin (Cur) into layered double hydroxide (LDH). Then, the Cur/LDH was assembled with carbon nitride quantum dots (CNQDs) through electrostatic adsorption. Acidic microenvironment–responsive nanocomposite (Cur/LDH/CNQDs) was constructed and used for tumor treatment. The as-synthesized Cur/LDH/CNQDs exhibits good biocompatibility and chemodynamic properties. In addition, the releases of Fe(II) ions (78%) and Cur (85%) are accelerated under acidic pH conditions that mimic the tumor microenvironment. The results show that the combination of chemotherapy and CDT can enhance its tumor-killing ability compared with single therapy. In essence, Cur/LDH/CNQDs shows a good effect in combined chemotherapy/CDT treatment of tumor cells and provide a promising alternative for combined tumor therapy.
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JOURNAL OF POROUS MATERIALS
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2024
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IF 2.5
Shi Xiang,Wang Ke,Wang Minxin,Yuan Hong
UiO-66 specimens having different acetic acid/ZrCl 4 molar ratios were prepared and pyrolyzed to ZrO 2 as supports for Pt and Ni, intended to catalyze the decarboxylation of oleic acid. Brunauer-Emmett-Teller surface area analyses, NH 3 temperature-programmed desorption and pyridine adsorption infrared spectroscopy showed that the material made using an acetic acid/ZrCl 4 molar ratio of 100 (ZrO 2 -100) had the largest specific surface area, acid amount and acid strength values. The yield of C 8 -C 17 alkanes obtained from Ni/ZrO 2 -100 exceeded that provided by Pt/ZrO 2 -100 because the latter possessed more acidic sites than the former, which excessively cracked long-chain hydrocarbons. The 1 wt% Ni/ZrO 2 -100 catalyst showed the best catalytic performance, with 96.4% conversion of oleic acid and an 80.6% yield of C 8 -C 17 alkanes after 4 h at 340 °C under a CO 2 atmosphere at a pressure of 18 bar. The conversion of oleic acid remained almost unchanged after 4 reuses of this catalyst whereas the yield of C 8 -C 17 alkanes decreased to 66.7%. This result is attributed to a loss of acidic sites and an increase in carbon build-up.
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RARE METALS
·
2025
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IF 11
Wang Dan-Dan,Xu Meng-Yang,Lin Zhao-Xin,Wu Jia-Hui,Yang Wei-Ting,Li Hong-Ji,Su Zhong-Min
The goal of photocatalytic CO 2 reduction is to obtain a single energy-bearing product with high efficiency and stability. Consequently, constructing highly selective photocatalysts with enhanced surface and optoelectronic properties is crucial for achieving this objective. Here, we have developed a simple one-pot vulcanization method to synthesize a MIL-68(In)-derived CdIn 2 S 4 /In 2 S 3 heterojunction that exhibited stable and high selectivity. Multiple characterizations of the CdIn 2 S 4 /In 2 S 3 heterojunction revealed a hierarchical tubular structure with numerous surface reactive sites, a high visible-light utilization rate ( λ < 600 nm), efficient charge separation, and a prolonged charge-carrier lifetime. Moreover, an S-scheme charge transfer mechanism, based on the interleaved band between the two components, improved the reduction capability of the electrons. Benefiting from the compositional and structural synergy, the yield CO by CdIn 2 S 4 /In 2 S 3 -250 (CI-250) reached 135.62 μmol·g −1 ·h −1 , which was 49.32 times and 32.88 times higher than that of In 2 S 3 and CdIn 2 S 4 , respectively. The CdIn 2 S 4 /In 2 S 3 heterojunction exhibited a quantum efficiency of 4.23% with a CO selectivity of 71%. Four cycle tests confirmed the good stability and recyclability of the CI-250. This work provides a new approach for designing and preparing high-performance hollow MOFs-based photocatalysts for scalable and sustainable CO 2 reduction.
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MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 4
·1-9
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IF 5.3
Zheng Wenhan,Li Min,Zhang Zhengping,Lou Zhixuan,Liu Yanbin,Yao Yuanyuan,Chen Lifen,Lin Bingyong,Wang Yueliang,Guo Longhua
A sandwich plasmonic coupled surface enhanced Raman spectroscopy (SERS) tape is proposed prepared by peeling the chemical printed silver nanocorals (AgNCs) from Cu sheet with adhesive tape, which can sample targets from food surface and sandwich them between substrates and Cu sheet for SERS detection. The solid-to-solid transformation method for fabricating SERS tapes can effectively avoid the weakening of tape stickiness during the preparation process. The sandwich plasmonic coupled structure of AgNC substrate, targets, and Cu sheet display excellent SERS activity (EF = 1.62 × 10 7 ) for sensitive determination of analytes. In addition, due to the high heat conductivity of Cu sheet, the thermal effect of laser irradiation during SERS detection cannot damage the AgNC tapes, which ensures the reproducibility of subsequent quantification. The sandwich plasmonic coupled SERS tape is demonstrated to quantify malachite green (MG) and methyl parathion (MP) with good linear coefficients (> 0.98) by two typical calibration plots under different concentration ranges. The limit of detection (LOD) of the method is 0.17 ng/cm 2 and 0.48 μg/cm 2 (S/N = 3) for MG and MP. This method can realize the quantitative determination of MP and MG on the surface of fruits and fish scale with recoveries of 93–113%. The satisfactory detection results demonstrate the proposed sandwich plasmonic coupled AgNC tape can be successfully applied to SERS-based point-of-care testing (POCT) for pesticide residue determination, which will provide a new path for designing and constructing SERS tapes. Graphical Abstract
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PubMed
高影响因子
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
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2024
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IF 3.1
Wen Yao,Chen Jiawen
The ultrasonic-assisted deep eutectic solvent method was used to extract the polysaccharides of Pericarpium Citri Reticulatae (PCRP), and the ultrasound-assisted DES extraction process was optimized by Box-Behnken response surface test using the extraction rate of the PCRP as an index; the in vitro activities of purified the PCRP(PCRPs-1) were investigated by determining the scavenging rate of DPPH• and ABTS• + as well as by enzyme inhibition assay. The monosaccharide composition was analyzed by HPLC. The best process conditions for response surface optimization were a material-liquid ratio of 1:37 g/mL, water content of 44%, time of 89 min, and power of 320 W. The polysaccharide extraction rate was measured to be 5.41%, which was well optimized when compared with that of the ordinary aqueous extraction method of 3.92%. By α-glucosidase and α-amylase inhibition activity test, it showed that the PCRPs-1 had hypoglycemic activity. The DPPH radical scavenging activity test and ABTS + scavenging activity test indicated that the PCRPs-1 had good biological activity. Analysis of the monosaccharide fractions showed that the PCRPs-1 consisted of mannose, rhamnose, glucuronic acid, galacturonic acid, glucose, galactose, xylose, and arabinose, with molar ratios of 1:39.24:4.41:8.91:7.83:86.00:1.02:9.17. The activity studies showed that PCRPs-1 possessed certain hypoglycaemic and antioxidant activities.
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高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 9
·1-9
·
IF 5.3
Xiang Jiawang,Zhang Bing,Yuan Yuan,Zhao Zhihuan,Lin Jianying,Li Jing
A novel signal amplification strategy was developed by combining near-infrared light with MoS 2 /CuO/Au nanocomposite for building a colorimetric immunoassay. First, MoS 2 /CuO/Au nanocomposite was synthesized by precipitation and photoreduction methods and characterized by scanning electron microscopy (SEM) and X-ray powder diffraction (XRD). MoS 2 /CuO/Au nanocomposite has oxidase-like activity and can oxidize TMB to form a blue product (TMBox). Further, the catalytic oxidation of TMB was accelerated under near-infrared (NIR) laser radiation. The sandwich-type colorimetric immunoassay was constructed using MoS 2 /CuO/Au nanocomposite. Under the enhancement of near-infrared light, carcinoembryonic antigen (CEA) was sensitively detected in the range 0.1 to 40 ng/mL with the limit of detection of 0.03 ng/mL. Moreover, the immunosensor has excellent selectivity and anti-interference, good repeatability, and stability. Graphical Abstract
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高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-17
·
IF 15.7
Qin Wenpin,Ma Zhangyu,Bai Guo,Qin Wen,Li Ling,Hao Dongxiao,Wang Yuzhu,Yan Jianfei,Han Xiaoxiao,Niu Wen,Niu Lina,Jiao Kai
Treating osteoarthritis (OA) associated pain is a challenge with the potential to significantly improve patients lives. Here, we report on a hydrogel for extracellular RNA scavenging and releasing bevacizumab to block neurovascularization at the osteochondral interface, thereby mitigating OA pain and disease progression. The hydrogel is formed by cross-linking aldehyde-phenylboronic acid-modified sodium alginate/polyethyleneimine-grafted protocatechuic acid (OSAP/PPCA) and bevacizumab sustained-release nanoparticles (BGN@Be), termed OSPPB. The dynamic Schiff base bonds and boronic ester bonds allow for injectability, self-healing, and pH/reactive oxygen species dual responsiveness. The OSPPB hydrogel can significantly inhibit angiogenesis and neurogenesis in vitro. In an in vivo OA model, intraarticular injection of OSPPB accelerates the healing process of condyles and alleviates chronic pain by inhibiting neurovascularization at the osteochondral interface. The injectable hydrogel represents a promising technique to treat OA and OA associated pain.
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高影响因子
Journal of Central South University
·
2024
·Vol. 31
·期 3
·796-812
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IF 3.7
Guan Zhi-wen,Jiao Fen,Wang Xu,Qin Wen-qing,Fu Li-wen,Zhang Zheng-quan,Li Wei
In this paper, the inhibition ability of tetrasodium pyrophosphate (TSPP), sodium tripolyphosphate (STPP) and sodium hexametaphosphate (SHMP) to scheelite, fluorite and calcite was predicted by performance calculation and further verified by micro-flotation test. The results of hydrophile lipophilic balance (HLB) calculation, group electronegative calculation and micro-flotation test indicated that the inhibition ability of phosphate to the three minerals increases with the increase of the number of phosphate groups and the order of inhibition ability of the three inorganic phosphates was SHMP > STPP > TSPP. STPP had great potential for flotation separation of scheelite from fluorite and calcite. The order of inhibition ability of STPP against the three calcium-bearing minerals is calcite>fluorite>scheelite. The results of contact angle measurement, adsorption amount measurement, X-ray photoelectron spectroscopy (XPS) analysis and atomic force microscope (AFM) imaging presented that the adsorption of STPP on the fluorite and calcite surface was much larger than that on the scheelite surface. The weak adsorption of STPP on the scheelite hardly influenced the collection of sodium oleate (NaOL). STPP could complex with Ca 2+ on the surface of fluorite and calcite, and hinder the subsequent adsorption of NaOL. The results can provide guiding significance for the flotation of scheelite and the screening of inhibitors for calcium-bearing gangue minerals.
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JOURNAL OF MOLECULAR HISTOLOGY
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2024
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IF 2.9
Cong Peiwei,Shang Bing,Zhang Lina,Wu Zhaoli,Wang Yanan,Li Jia,Zhang Lin
Polycystic ovary syndrome (PCOS) is an endocrine disease, and its pathogenesis and treatment are still unclear. Hexokinase domain component 1 (HKDC1) participates in regulating mitochondrial function and glycolysis. However, its role in PCOS development remains unrevealed. Here, female C57BL/6 mice were intraperitoneally injected with dehydroepiandrosterone (DHEA; 60 mg/kg body weight) to establish an in vivo model of PCOS. In vitro, KGN cells, a human ovarian granular cell line, were used to explore the potential mechanisms. DHEA-treated mice exhibited a disrupted estrus cycle, abnormal hormone levels, and insulin resistance. Dysfunction in mitochondria and glycolysis is the main reason for PCOS-related growth inhibition of ovarian granular cells. Here, we found that the structure of mitochondria was impaired, less ATP was generated and more mitochondrial Reactive Oxygen Species were produced in HKDC1-silenced KGN cells. Moreover, HKDC1 knockdown inhibited glucose consumption and decreased the production of glucose-6-phosphate and lactic acid. Conclusively, HKDC1 protects ovarian granulocyte cells from DHEA-related damage at least partly by preserving mitochondrial function and maintaining glycolysis. Graphical abstract
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International Journal of Minerals Metallurgy and Materials
·
2025
·Vol. 32
·期 4
·964-972
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IF 7.2
Han Dan,Liu Xiaoru,Li Donghui,Shi Jiexu,Wang Yu,Wang Yuxuan,Wang Hongtao,Sang Shengbo
In this work, we realized a room-temperature nitrogen dioxide (NO 2 ) gas sensor based on a platinum (Pt)-loaded nanoporous gallium nitride (NP-GaN) sensing material using the thermal reduction method and coreduction with the catalysis of polyols. The gas sensor gained excellent sensitivity to NO 2 at a concentration range of 200 ppm to 100 ppb, benefiting from the loading of Pt nanoparticles, and exhibited a short response time (22 s) and recovery time (170 s) to 100 ppm of NO 2 at room temperature with excellent selectivity to NO 2 compared with other gases. This phenomenon was attributed to the spillover effect and the synergic electronic interaction with semiconductor materials of Pt, which not only provided more electrons for the adsorption of NO 2 molecules but also occupied effective sites, causing poor sites for other gases. The low detection limit of Pt/NP-GaN was 100 ppb, and the gas sensor still had a fast response 70 d after fabrication. Besides, the gas-sensing mechanism of the gas sensor was further elaborated to determine the reason leading to its improved properties. The significant spillover impact and oxygen dissociation of Pt provided advantages to its synergic electronic interaction with semiconductor materials, leading to the improvement of the gas properties of gas sensors.
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