npj Flexible Electronics
·
2024
·Vol. 8
·期 1
·1-8
·
IF 12.3
Zhang Jiaxue,Lu Qianying,Wu Ming,Sun Yuping,Wang Shaolei,Wang Xiaoliang,Lu Ming-Hui,Kong Desheng
Stretchable displays that combine light-emitting capabilities with mechanical compliance are essential building blocks of next-generation wearable electronics. However, their widespread applications are currently limited by complex device architecture, limited pixel density, and immature fabrication processes. In this study, we present the device design and material developments of intrinsically stretchable light-emitting drawing displays that can show arbitrary hand-drawing features. The alternating-current electroluminescent display uses a simplified architecture comprising coplanar interdigitated liquid metal electrodes, an electroluminescent layer, and a dielectric encapsulation layer. Ink patterns on the device are coupled with the interdigitated electrodes under alternating voltage stimulations, generating localized electric fields for bright emissions. Various inks are prepared for painting, stamping, and stencil printing. Arbitrary luminous features on the devices can be either long-lasting or transient in characteristics. These skin-like devices are made entirely of compliant materials that can withstand bending, twisting, and stretching manipulations. Due to the excellent mechanical deformability, the drawing displays can be conformally laminated on the skin as body-integrated optoelectronic communication devices for graphic information.
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JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
·
2025
·
IF 2
Zhang Dongbo,Tang Xinyue,Wang Ning,Xiao Mingwei,Yan Jiangrong,Zhang Yongsheng
High-entropy oxides used as thermal barrier coating materials have attracted considerable attention from scientific communities owing to their unique properties, such as low thermal conductivity and good stability at high temperatures. In this study, a new (La 0.2 Gd 0.2 Zr 0.2 Ce 0.2 Ho 0.2 )O 2-δ ((LGZCH)O) fluorite-structured high-entropy oxide was successfully synthesized through a solid-state reaction at 1400 °C. The resulting material demonstrated good phase stability after sintering at high temperatures. The microstructure, microscopic morphology, ionic valence, compositional distribution, optical properties, thermal conductivity, thermal expansion properties, and mechanical properties of (LGZCH)O were investigated. X-ray diffraction results showed that the (LGZCH)O fluorite-structured high-entropy oxide exhibited good stability during sintering at different temperatures with an optimum sintering temperature of 1580 °C. Ce 4+ converted to Ce 3+ at high temperatures. Scanning electron microscopy results showed that the material had a high porosity of approximately 28.9% after sintering at 1580 °C. (LGZCH)O had a higher infrared radiation emissivity of 82.2%-87.6% in the range of 2.5-6.0 μm indicating that it had better thermal radiation shielding performance. After porosity modification, the thermal conductivity ranged from 1.27 to 1.00 W m −1 K −1 from room temperature to 1000 °C, which is considerably lower than that of yttria-stabilized zirconia. Additionally, (LGZCH)O exhibited low coefficients of thermal expansion measuring 9.65 × 10 −6 K −1 and 10.13 × 10 −6 K −1 at 1000 and 1200 °C, respectively. The hardness and Young’s modulus of the bulk (LGZCH)O measured via nanoindentation tests were 8.86 GPa and 153.98 GPa, respectively, which are marginally inferior to those of YSZ. Therefore, (LGZCH)O can be considered a promising candidate material for thermal barrier coatings.
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INTERNATIONAL JOURNAL OF THERMOPHYSICS
·
2024
·Vol. 45
·期 6
·1-18
·
IF 2.5
Zheng Qiang,Yang Fuxin,Tan Houzhang,Wang Xiaopo
Deep eutectic solvents (DES) have attracted more attention due to the excellent performance and environmental protection. In the study and application of DES, the presence of water cannot be ignored. Thus, it is of importance to study the effect of water on DES. In this work, tetrabutylammonium chloride (TBAC) was chosen as the hydrogen bond acceptor (HBA). Decanoic acid (DEC) and octanoic acid (OC) were chosen as the hydrogen bond donor (HBD). Then, two kinds of DES were prepared with the mole ratio of 1:2 for HBA:HBD. The water was added into the sample to form the mixing system. The properties of these DES and their aqueous solutions were analyzed. The thermogravimetric (TG) experiment was conducted to obtain the TG curves for the thermal stability evaluation. The data of density and viscosity for (1 − x )DES– x H 2 O ( x represents the molar fractions of H 2 O) were measured at the temperatures ranging from 303.15 K to 343.15 K. Furthermore, the hard sphere model was introduced for the predictions of viscosity with the average absolute relative deviation for the pure DES and their aqueous solution less than 2.71 % and 7.65 %, respectively. It indicates the fine prediction of these models. Moreover, the excess molar volume, the viscosity deviation and the excess molar Gibbs energy of activation were calculated for the further analysis of the interactions between DES and water.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
·
IF 15.7
Wang Dawei,Lin Fangxu,Luo Heng,Zhou Jinhui,Zhang Wenshu,Li Lu,Wei Yi,Zhang Qinghua,Gu Lin,Wang Yanfei,Luo Mingchuan,Lv Fan,Guo Shaojun
Using metal oxides to disperse iridium (Ir) in the anode layer proves effective for lowering Ir loading in proton exchange membrane water electrolyzers (PEMWE). However, the reported low-Ir-based catalysts still suffer from unsatisfying electrolytic efficiency and durability under practical industrial working conditions, mainly due to insufficient catalytic activity and mass transport in the catalyst layer. Herein we report a class of porous heterogeneous nanosheet catalyst with abundant Ir-O-Mn bonds, achieving a notable mass activity of 4 A mg Ir −1 for oxygen evolution reaction at an overpotential of 300 mV, which is 150.6 times higher than that of commercial IrO 2 . Ir-O-Mn bonds are unraveled to serve as efficient charge-transfer channels between in-situ electrochemically-formed IrO x clusters and MnO x matrix, fostering the generation and stabilization of highly active Ir 3+ species. Notably, Ir/MnO x -based PEMWE demonstrates comparable performance under 10-fold lower Ir loading (0.2 mg Ir cm −2 ), taking a low cell voltage of 1.63 V to deliver 1 A cm −2 for over 300 h, which positions it among the elite of low Ir-based PEMWEs.
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JOURNAL OF MOLECULAR MEDICINE-JMM
·
2024
·
IF 4.8
Su Qi,Chen Kun,Ren Jiayan,Zhang Yu,Han Xu,Leong Sze Wei,Wang Jingjing,Wu Qing,Tu Kaihui,Sarwar Ammar,Zhang Yanmin
Abstract Non-small cell lung cancer (NSCLC) is a highly malignant tumor with a poor prognosis. Hypoxia conditions affect multiple cellular processes promoting the adaptation and progression of cancer cells via the activation of hypoxia-inducible factors (HIF) and subsequent transcription activation of their target genes. Preliminary studies have suggested that estrogen receptor β (ERβ) might play a promoting role in the progression of NSCLC. However, the precise mechanisms, particularly its connection to HIF-1α-mediated modulation under hypoxia, remain unclear. Our findings demonstrated that the overexpression of ERβ, not ERα, increased cell proliferation and inhibition of apoptosis in NSCLC cells and xenografts. Tissue microarray staining revealed a strong correlation between the protein expression of HIF-1α and ERβ. HIF-1α induced ERβ gene transcription and protein expression in CoCl 2 -induced hypoxia, 1% O 2 incubation, or HIF-1α overexpressing cells. ChIP identified HIF-1α binding to a hypoxia response element in the ESR2 promoter. The suppression of HIF-1α and ERβ both in vitro and in vivo effectively reduced the tumor growth, thus emphasizing the promising prospects of targeting HIF-1α and ERβ as a therapeutic approach for the treatment of NSCLC. Key messages
ERβ, not ERα, increases cell proliferation and inhibition of apoptosis in NSCLC cells and xenografts.
A strong correlation exists between the protein expression of HIF-1α and ERβ.
HIF-1α induced ERβ gene transcription and protein expression in hypoxic cells via binding to HRE in the ESR2 promoter.
The suppression of HIF-1α and ERβ both in vitro and in vivo effectively reduced the NSCLC tumor growth.
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Journal of Food Measurement and Characterization
·
2024
·
IF 2.9
Wen Mengting,Ni Xuewen,Xiao Weilu,Li Yanlei,Gao Zhiming
Currently, thickeners are frequently added to foods to ensure safe diets for dysphagia patients. Konjac glucomannan (KGM) is a commonly used food thickener with health benefits as an excellent dietary fiber, but its rheological properties, such as no yield stress and poor gelling, prevent its direct use as a dysphagia thickener. This study exploited the potential of KGM as a dysphagia thickener through its synergistic interaction with xanthan gum (XG) and investigated the effects of dispersion media (water, juice, and soy milk) on the rheological properties and oral tribology of the KGM-XG thickener. The KGM-XG thickener (15:5 mass ratio of KGM to XG) was added to the dispersion media in an amount of 0.3–0.9% (w/w). The results showed the thickener had the strongest pseudoplasticity and apparent viscosity in water, exhibiting weak gel properties and yield behavior; whereas in juice and soy milk, apparent viscosity decreased due to the medium components interfering with KGM and XG synergistic interaction, and weak gel properties and yield behavior were only exhibited at higher levels (> 0.3%, w/w). The thickener had better ability to resist deformation and recovery in water than in juice and soy milk. The Stribeck curves effectively reflected the oral tribological behavior of the thickened systems, and the addition of the thickener reduced the friction coefficients of water and juice but had no significant effect on soy milk. Overall, KGM-XG is a promising thickener for dysphagia diets and offers a viable strategy for adding more dietary fiber to dietary formulations.
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IONICS
·
2024
·Vol. 30
·期 7
·3819-3829
·
IF 2.4
Zhang Caihong,Zhong Yan,Tu Hong,Yang Zhihao,Chen Guangping,Zhu Xinghua
Iron phosphate (FePO 4 ·2H 2 O) has emerged as the mainstream process for the synthesis of lithium iron phosphate (LiFePO 4 ), whereas FePO 4 ·2H 2 O produced by different processes also has a great influence on the performance of LiFePO 4 . In this paper, FePO 4 ·2H 2 O was produced by two different processes, in which FeSO 4 ferrous and Fe(NO 3 ) 3 ·9H 2 O ferric were used, respectively. After dehydration under the same conditions, a carbon-coated lithium iron phosphate (LiFePO 4 /C) cathode material was synthesized by a high-temperature solid phase method. The results demonstrated that FePO 4 ·2H 2 O contained different impurities due to different raw materials, which led to different particle sizes, specific surface areas, microscopic morphology, and crystal structures. The difference of FePO 4 ·2H 2 O eventually resulted in the difference of LiFePO 4 /C cathode materials in micro-morphology and crystal structure, which affected the electrochemical performance. Under the premise of comprehensively considering the cost and quality of FePO 4 ·2H 2 O, improving the purity of FePO 4 ·2H 2 O is an important method to improve the electrochemical performance of LiFePO 4 /C cathode materials. Simultaneously, it is also expected to provide theoretical guidance for the preparation of lower-cost and better-quality LiFePO 4 /C cathode materials.
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Scientific Reports
·
2024
·Vol. 14
·期 1
·1-12
·
IF 3.8
Hu Deliang,Yang Yuqing,Fang Lei,Fan Shijie,Lin Ling,Luo Puying,Xiong Yuanhuan,Su Yufang
Isoliquiritigenin (ISL), a naturally occurring flavonoid derived from licorice root, exhibits antioxidant, anticancer, anti-inflammatory, and anti-allergic properties, and is frequently detected in both environmental and human samples. Previous studies from our lab have demonstrated that ISL exposure can lead to developmental deformities and aberrant immune responses. However, the molecular mechanisms underlying ISL toxicity in zebrafish embryos remain incompletely elucidated. Therefore, this study aimed to elucidate the effects of ISL exposure on endoplasmic reticulum (ER) stress in zebrafish embryos by assessing the expression levels of ER stress markers HSPA5 and CHOP , along with associated apoptosis factors, under various ISL concentrations, with tunicamycin (TM) serving as a positive control. Furthermore, targeted analyses of ER stress-related pathways were conducted using RNA transcriptome sequencing, and the up-regulated gene was verified by western blot. The results revealed that ISL exposure significantly elevated the expression levels of HSPA5 and CHOP , concomitantly activating ER stress pathways, including pPERK-eIF2α-ATF4 and ATF6 pathways in zebrafish embryos. These findings suggest that the activation of endoplasmic reticulum stress signaling pathways may contribute to the developmental deformities observed in zebrafish embryos following ISL exposure, thereby highlighting the potential ecological risks associated with ISL usage.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2024
·Vol. 35
·期 32
·1-11
·
IF 2.8
Yang Shiju,Qian Libing,Zhang Bo,Wang Tingting,Li Yunfei
The method of preparation is a critical factor affecting the structure and properties of Bi 2 O 3 material. In this work, Bi 2 O 3 was synthesized through calcination (denoted as Bi 2 O 3 –C) and hydrothermal methods (denoted as Bi 2 O 3 –H), utilizing bismuth-based metal–organic framework (Bi–MOF) as the precursor. As an electrode material for supercapacitors, Bi 2 O 3 –H demonstrated outstanding rate performance (515 F g −1 at 50 A g −1 ) and remarkable cycle stability (74% retention after 4000 cycles). Subsequently, the Bi 2 O 3 -H underwent further processing through electron beam irradiation (EBI), resulting in a sample designated as Bi 2 O 3 –I. Following EBI treatment, the crystalline characteristics of Bi 2 O 3 –I and the concentration of oxygen vacancies (OVs) exhibited a significant improvement, thereby augmenting the material's conductivity. Because the positively charged OVs can quickly attract OH − from the electrolyte to the electrode surface, thereby accelerating the REDOX reaction, the current control mechanism of Bi 2 O 3 –I is partially derived from a surface-controlled pseudo-capacitance process. The irradiated Bi 2 O 3 -I electrode demonstrated superior capacitance (990 F −1 at 2 A g −1 ), enhanced rate performance (585 F −1 at 50 A g −1 ), and remarkable cycling stability (83% retention after 4000 cycles).
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RARE METALS
·
2025
·
IF 11
Dong Yu-Guo,Kong Wen-Jing,Ma Zhuang,Yang Yong,Wang Ping,Sheng Shi-Xiong,Dong Lin,Gu Xiao-Li,Chen Zu-Peng
The oxidation of lignin model compounds to esters via C–C bond cleavage has attracted considerable attention, as esters could be used as important polymer precursors and pharmaceutical intermediates. However, most studies focus on designing homogeneous or noble metal catalysts and conducting the reactions under basic conditions. Here, we report an efficient process for the C–C bond cleavage of lignin model compounds and selectively producing esters over different shaped CeO 2 (i.e., nanospheres (S), nanorods (R), nanoparticles (P), and nanocubes (C)) under base-free conditions. Specifically, the yield of methyl anisate from the aerobic oxidation of 1-(4-methoxyphenyl)ethanol reaches 77.6% over CeO 2 -S in one hour (91% in 9 h), exhibiting higher performance compared to other evaluated CeO 2 catalysts (6.4%–40.2%). Extensive characterizations and experimental investigations reveal that the density of weak base sites and oxygen vacancies on the CeO 2 surface is positively correlated with the yield of methyl esters. Furthermore, the reaction pathway is investigated, which confirms that 1-(4-methoxyphenyl)ethanol first undergoes two reactions (i.e., etherification and dehydrogenation) to produce intermediates of 1-methoxy-4-(1-methoxy-ethyl)-benzene and 1-(4-methoxyphenyl)ethanone, respectively, followed by a series of functional group transformations to generate the targeted methyl anisate ultimately. Graphical abstract
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JOURNAL OF NANOBIOTECHNOLOGY
·
2024
·Vol. 22
·期 1
·1-16
·
IF 10.6
Qin Xianyan,Zhang Luhan,Miao Yang-Bao,Jiang Linxi,Zou Liang,Wang Qin,Shi Yi
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by painful swelling and inflammation, arising from the immune system attacking on healthy cells. However, arthritic sites often experience increased lymph flow, hastening drug clearance and potentially reducing treatment effectiveness. To address this challenge, an in situ size amplification has been proposed to reduce lymphatic clearance and thereby enhance arthritis therapy. This system has been developed based on a conjugate of dexamethasone (Dex) and polysialic acid (PSA), linked via an acid-sensitive linker, supplemented with bis-5-hydroxytryptamine (Bis-5HT) on the PSA backbone. Under physiological conditions, the system autonomously assembles into stable nanoparticles (PD5NPs), facilitating prolonged circulation and targeted delivery to inflamed joints. Upon arrival at arthritic joints, Bis-5HT reacts to elevated myeloperoxidase (MPO) levels and oxidative stress, prompting particle aggregation and in-situ size amplification. This in situ size amplification nanocarrier effectively reduces lymphatic clearance and serves as reservoirs for sustained Dex release in acidic pH environments within arthritic sites, thus continuously alleviating RA symptoms. Moreover, investigation on the underlying mechanism elucidates how the in situ size amplification nanocarrier influences the transportation of PD5NPs from inflamed joints to lymphatic vessels. Our study offers valuable insights for optimizing nanomedicine performance in vivo and augmenting therapeutic efficacy.Graphical
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Journal of Coatings Technology and Research
·
2025
·
IF 2.8
Lin Zecheng,Duan Yuan,Ran Liuqun,Ni Simeng,Ding Yongbo,Shen Liang
In this investigation, the alkyd polyol was synthesized via the fatty acid method using oleic acid, trimethylolpropane, neopentyl glycol, and phthalic anhydride as raw materials. A series of water-based polyurethane dispersions (WPUCOs) were prepared by incorporating different levels of branched flexible castor oil into the formulation. The hydroxyl content provided by castor oil accounted for 0%, 10%, 20%, 30%, 40%, and 50% of the total hydroxyl content provided by castor oil and the alkyd polyol, and these variations were designated as WPUCO-0, WPUCO-10, WPUCO-20, WPUCO-30, WPUCO-40, and WPUCO-50, respectively. The WPUCOs were synthesized using an alkyd polyol, castor oil, 4,4'-dicyclohexylmethane diisocyanate (H 12 MDI), and 2,2-dimethylolpropionic acid as key components. These WPUCOs were analyzed using Fourier transform infrared spectroscopy, laser diffraction particle size analysis, and rheological measurements. Waterborne polyurethane-amino resin curing films based on the above-mentioned WPUCOs were then fabricated and characterized through thermogravimetric analysis, differential scanning calorimetry, contact angle measurements, water absorption tests, and gel content determination. Furthermore, waterborne polyurethane-amino baking coatings were also formulated using WPUCOs to evaluate their performance. The results showed that yellowish WPUCOs were successfully prepared. The viscosity and particle size of WPUCOs are observed to rise as the proportion of castor oil in the formulation increases. Among all formulations tested, WPUCO-30 exhibited superior film properties and coating performances. For instance, the water absorption ratio of the resulting waterborne polyurethane-amino resin curing films based on WPUCO-30 was only 2.81%, while achieving a gel content of 93.85%. Additionally, the pencil hardness and impact resistance values for the waterborne polyurethane-amino baking coating based on WPUCO-30 reached 3H and 50 kg·cm, respectively, and glossiness measured at a 20° angle reached 89.6 GU. Moreover, the number of times the coating could withstand acetone scrubbing reached up to 12,408 times. Therefore, castor oil containing three-chain structures can be effectively utilized to enhance the performance characteristics of waterborne polyurethane-amino resin baking films/coatings.
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