Journal of X-Ray Science and Technology
·
2024
·
IF 1.7
Yichi Zhang,Fen Tao,Ruoyang Gao,Ling Zhang,Jun Wang,Guohao Du,Tiqiao Xiao,Biao Deng
BackgroundK-edge subtraction (KES) tomography has been extensively utilized in the field of elemental sensitive imaging due to its high spatial resolution, rapid acquisition, and three-dimensional (3D) imaging capabilities. However, previous studies have primarily focused on the qualitative analysis of element contents, rather than quantitative assessment.ObjectiveThe current study proposes a novel method for quantitative elemental analysis based on K-edge subtraction tomography.MethodsThe linear correlation between the slice grayscale of standard samples and the difference in their linear absorption coefficients is confirmed. This finding suggests that the grayscale data from slices may be employed to perform quantitative estimations of elemental compositions.ResultsIn order to verify the accuracy and validity of this method, the target element contents in standard and actual samples are quantitatively analyzed, respectively. The results demonstrate that the method is capable of achieving nanometer-resolved quantitative elemental sensitive imaging with a relative error of less than 3% in the target elemental content.ConclusionsThe method described in this paper is expected to expand the scope of applications for K-edge subtraction tomography and provide a novel approach to achieve more precise and convenient quantitative elemental analysis.
研究领域:
医学影像学
·
材料科学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2021
·Vol. 104
·期 8
·4119-4130
·
IF 3.784
Yu Huang,Liang Shu,Suwei Zhang,Zhen Zhou,Yue-Yu-Shan Cheng,Biaolin Peng,Lisha Liu,Yuanyuan Zhang,Xuping Wang,Jing-Feng Li
With the development of advanced electrical and electronic devices and the requirement of environmental protection, lead-free dielectric capacitors with excellent energy storage performance have aroused great attention. However, it is a great challenge to achieve both large energy storage density and high efficiency simultaneously in dielectric capacitors. This work investigates the energy storage performance of sol-gel-processed (K,Na)NbO 3 -based lead-free ferroelectric films on silicon substrates with compositions of 0.95(K 0.49 Na 0.49 Li 0.02 )(Nb 0.8 Ta 0.2 )O 3 -0.05CaZrO 3 - x mol% Mn (KNN-LT-CZ5- x mol% Mn). The appropriate amount of Mn-doping facilitates the coexistence of orthorhombic and tetragonal phases, suppresses the leakage current, and considerably enhances the breakdown strengths of KNN-LT-CZ5 films. Consequently, large recoverable energy storage density up to 64.6 J cm −3 with a high efficiency of 84.6% under an electric field of 3080 kV cm −1 are achieved in KNN-LT-CZ5-5 mol% Mn film. This, to the best of our knowledge, is superior to the majority of both the lead-based and lead-free films on silicon substrates and thus demonstrates great potentials of (K,Na)NbO 3 -based lead-free films as dielectric energy storage materials.
研究领域:
材料科学
·
能源存储
✓ 已验证
DOI
高影响因子
Cell Death & Disease
·
2025
·Vol. 16
·期 1
·1-15
·
IF 9.6
Dai Xiaochan,Yang Xi,Feng Yifan,Wu Xinyuan,Ju Yahan,Zou Rong,Yuan Fei
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in people over the age of 55. AMD currently affects approximately 8% of the world’s population, and the number is growing as the global population ages. Growing evidence suggests that pathological choroidal neovascularization (CNV) is often related to more severe and rapid vision loss and blindness associated with AMD. The typical clinical treatment is intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents. However, some patients do not respond well to this therapy, and the potential risks of long-term repeated injections cannot be ignored. Therefore, there is an urgent need to explore the specific mechanisms of CNV development and find new, safe, and effective treatments. In this study, our data indicate that ferroptotic damage of retinal pigment epithelium (RPE) and its induced VEGFA overexpression are critical promoting factors in the development of CNV. Vitamin K can mediate the protection of RPE cells from ferroptotic damage and regulate the expression of eIF2α-ATF4-VEGFA in a VKOR/FSP1-dependent manner, inhibiting new angiogenesis to alleviate CNV. On the contrary, vitamin K antagonists (VKA) represented by warfarin, can promote RPE ferroptotic damage and related vascular proliferation in mice and eventually aggravate CNV lesions. However, vitamin K still showed significant protective effects even in the presence of VKA. Due to its significant anti-ferroptosis and anti-neovascular effects, as well as its relative safety and convenience of use, vitamin K has excellent potential in the treatment of CNV and is expected to become a clinically effective and safe new CNV treatment strategy.
研究领域:
眼科学
·
分子生物学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Coatings
·
2023
·Vol. 13
·期 6
·1085
·
IF 3.4
Zhenchuan Lu,Kamale Tuokedaerhan,Haotian Cai,Hongguo Du,Renjia Zhang
This article presents the sol-gel method for depositing La2O3thin films on n-type Si substrates and quartz substrates, and investigates the impact of annealing temperature on the microcomposition, surface morphology, optical properties, and band characteristics of the films. X-ray diffraction (XRD) analysis indicates that the films are amorphous below 500 °C, with annealing resulting in a hexagonal-phase La2O3(h-a2O3) and new non-hydrated impurities. Fourier-transform infrared (FTIR) analysis reveals that the prepared La2O3film is unaffected by moisture. Atomic force microscopy (AFM) and scanning electron microscopy (SEM) provide evidence that the La2O3film has a smooth, uniform surface without cracks. The roughness increases from 0.426 nm to 1.200 nm, and the film thins from 54.85 nm to 49.80 nm as the annealing temperature rises. The film’s transmittance is above 75%, as measured by UV-Vis, and the calculated optical bandgap increases from 5.11 eV to 5.75 eV. The calculated band offset of the La2O3film is greater than 1 eV, which meets the minimum requirements for MOS devices, thus providing promising prospects for La2O3films in MOS applications.Keywords:high k gate dielectric;sol-gel;La2O3;thin film
研究领域:
材料科学
·
半导体物理
✓ 已验证
产品关联
DOI
高影响因子
Journal of Physical Chemistry Letters
·
2023
·
IF 5.7
Yirong Su,Peng Ran,Juan Hui,Yang “Michael” Yang
Conventional flat panel X-ray imaging (FPXI) employs a single scintillator for X-ray conversion, which lacks energy spectrum information. The recent innovation of employing multilayer scintillators offers a route for multispectral X-ray imaging. However, the principles guiding optimal multilayer scintillator configuration selection and quantitative analysis models remain largely unexplored. Here, we propose to adopt the K-edge absorption coefficient as a key parameter for selecting tandem scintillator combinations and to utilize the coefficient matrix to calculate the absorption efficiency spectrum of the sample. Through a dual scintillator example comprising C4H12NMnCl3 and Cs3Cu2I5, we establish a streamlined quantitative framework for deducing X-ray spectra from scintillation spectra, with an average relative error of 6.28% between the calculated and measured sample absorption spectrum. This insight forms the foundation for our quantitative method to distinguish the material densities. Leveraging this tandem scintillator configuration, in conjunction with our analytical tools, we successfully demonstrate the inherent merits of dual-energy X-ray imaging for discerning materials with varied densities and thicknesses.
研究领域:
医学成像
·
放射学
·
材料科学
·
X射线光谱学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry C
·
2019
·Vol. 7
·期 23
·6914-6923
·
IF 6.641
Yi-Xuan Liu,Hao-Cheng Thong,Chunlin Zhao,Qing Liu,Xingyu Xu,Ke Wang,Jing-Feng Li
The understanding of certain basic issues in (K,Na)NbO3 (KNN)-based systems is still missing, one of which being the influence of ZrO2 addition on the behaviors of KNN-based solid solutions at trace levels possibly introduced during the process of material preparation. Herein, KNN solid solutions with trace ZrO2 addition (0, 0.01, 0.05, and 0.1 mol%) were prepared by a normal sintering method. The dielectric permittivity and the piezoelectric coefficient d33 reach the maximum (εr = 497 and d33 = 139 pC N−1) with 0.1 mol% ZrO2 addition. Moreover, the microscopic results supported by PFM are in agreement with those from the macroscopic perspective. To establish the relationship among the ZrO2 addition contents, the induced defects and the properties of the solid solutions, a related defect model is proposed to support the experimental observation and the origin of induced defects is discussed. The results demonstrate that the properties of the KNN solid solutions can be closely affected by trace zirconia addition.
研究领域:
材料科学
·
陶瓷材料
✓ 已验证
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2021
·
IF 5.909
Hailu Fu,Jilei Lin,Shuang Cao,Bosheng Chen,Renhua Huang,Hao Chen,Tao Ding,Pengfei Sun,Ligang Luo
A series of cobalt-based catalysts (Co 3 O 4 , Mn/Co 3 O 4 , K-Co 3 O 4, and K-Mn/Co 3 O 4 ) were prepared for toluene catalytic combustion and anti-K poisoning experiments. Co 3 O 4 catalyst has exhibited good performance in toluene oxidation , but it has poor anti-K poisoning performance. The Mn/Co 3 O 4 catalyst has shown excellent low-temperature catalytic activity , good resistance to K poisoning at T 90 of 226 °C, and achieved a complete toluene conversion at about 235 °C; the activity after the addition of K slightly reduced at T 90 of 237 °C. A series of characterizations indicated that adding Mn can effectively promote the Co 2+ ↔Co 3+ cycle, increase the Co 3+ content on the catalyst surface, and enhance the redox performance of the catalyst. On the other hand, MnO x intercepts K species and generates Mn-O-K, blocking most of the poisonous effects of K on cobalt oxide , thereby protecting the active species (Co 3+ and surface-adsorbed oxygen) and acidic sites on the Co 3 O 4 surface. Finally, GC-MS and in-situ infrared characterization were adopted to investigate the reaction mechanism of the catalysts. Two reaction paths of the Co 3 O 4 catalyst may co-occur. Still, the reaction path of the Mn/Co 3 O 4 catalyst is relatively simple; that is, the chemically adsorbed toluene molecules are oxidized through surface-active oxygen, after which various intermediate by-products are formed successively. Finally, they are completely degraded into CO 2 .
研究领域:
环境科学
·
催化化学
✓ 已验证
DOI
高影响因子
CHINESE JOURNAL OF PHYSICS
·
2024
·
IF 4.6
Zhuojia Xie,Zhengguang Zou,Changji Xu,Shenglin Zhong,Min Feng,Xinyu Jiang,Weijian Zhang,Xiuxin Zheng,Wenbin He
We prepared La 0.8- x K x Sr 0.2 Mn 0.95 Co 0.05 O 3 (0 ⩽ x ⩽ 0.1) (LKSMCO) through the modified sol-gel method (S-G) and its structure. Then, the magnetic, magnetocaloric, and critical behavior were analyzed. LKSMCO was confirmed to be the rhombohedral structure within the R-3c space group (No.167) using transmission electron microscopy and X-ray diffraction. For validating the chemical composition of LKSMCO, X-ray photoelectron spectroscopy and EDS were applied, showing that K + was successfully doped. Phase transition of LKSMCO from paramagnetic to ferromagnetic phase near Curie temperature (Tc) was confirmed with a Magnetic Property Measurement System (MPMS). Using normalization and Banerjee's criterion, LKSMCO was demonstrated to be the second-order magnetic phase transition (SOMPT). As shown from the applied magnetic field, the maximal magnetic entropy ( − Δ S M m a x ) of LKSMCO near Tc was 3.87 J/(kg K) ( x = 0.00), 4.28 J/(kg K) ( x = 0.05) and 4.44 J/(kg K) ( x = 0.10). We employed the Kouvel-Fisher approach (KF) and modified Arrott plots to confirm the values of γ, δ , and β . This indicates that critical exponents of LKSMCO were consistent with the Mean-filed model.
研究领域:
材料科学
·
物理学
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2015
·
IF 3.545
Shenguang Ge,Lina Zhang,Yan Zhang,Haiyun Liu,Jiadong Huang,Mei Yan,Jinghua Yu
A low-cost, simple, portable and sensitive paper-based electrochemical sensor was established for the detection of K-562 cell in point-of-care testing. The hybrid material of 3D Au nanoparticles/graphene (3D Au NPs/GN) with high specific surface area and ionic liquid (IL) with widened electrochemical windows improved the good biocompatibility and high conductivity was modified on paper working electrode (PWE) by the classic assembly method and then employed as the sensing surface. IL could not only enhance the electron transfer ability but also provide sensing recognition interface for the conjugation of Con A with cells, with the cell capture efficiency and the sensitivity of biosensor strengthened simultaneously. Concanavalin A (Con A) immobilization matrix was used to capture cells. As proof-of-concept, the paper-based electrochemical sensor for the detection of K-562 cells was developed. With such sandwich-type assay format, K-562 cells as model cells were captured on the surface of Con A/IL/3D AuNPs@GN/PWE. Con A-labeled dendritic PdAg NPs were captured on the surface of K-562 cells. Such dendritic PdAg NPs worked as catalysts promoting the oxidation of thionine (TH) by H 2 O 2 which was released from K-562 cells via the stimulation of phorbol 12-myristate-13-acetate (PMA). Therefore, the current signal response was dependent on the amount of PdAg NPs and the concentration of H 2 O 2 , the latter of which corresponded with the releasing amount from cells. So, the detection method of K-562 cell was also developed. Under optimized experimental conditions, 1.5×10 −14 mol of H 2 O 2 releasing from each cell was calculated. The linear range and the detection limit for K-562 cells were determined to be 1.0×10 3 –5.0×10 6 cells/mL and 200 cells/mL, respectively. Such as-prepared sensor showed excellent analytical performance with good fabrication reproducibility, acceptable precision and satisfied accuracy, providing a novel protocol in point-of-care testing of cells.
研究领域:
生物医学工程
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2021
·Vol. 105
·期 1
·461-468
·
IF 3.784
Baoyu Deng,Yiming Ma,Tianxiang Chen,Huajing Wang,Jinfeng Lin,Cong Lin,Xiao Wu,Chunlin Zhao,Tengfei Lin,Min Gao,Xinghua Zheng,Changqing Fang
Dense (K, Na)NbO 3 ceramics are successfully fabricated via the cold sintering process at 350°C under a uniaxial pressure of 400 MPa for 4 h. Equimolar KOH and NaOH solutions were utilized as a transient alkaline flux. The microstructure and dielectric properties were studied in detail. Scanning electron microscope and the relative densities reveal dense structures of the ceramics. After post-annealing at 800°C for 1 h, the ceramics show good electrical performance. The relative dielectric permittivity is 829 (at 10 kHz) at room temperature, and the piezoelectric constant ( d 33 ) reaches up to 148 pC/N. The cold sintering technique with equimolar KOH and NaOH solutions as a transient alkaline flux endow KNN ceramics with excellent dielectric and piezoelectric properties, showing a potential way to fabricating other KNN-based ceramics at low temperature.
研究领域:
材料科学
·
电子工程
✓ 已验证
产品关联
DOI
高影响因子
FUEL
·
2022
·
IF 8.035
Xiaohe Wang,Hongwei Chen,Maosheng Zhang,Chaoran Wang,Yufei Wang,Pu Bai,Libo Li,Wenfu Yan
Silicoaluminophosphate (SAPO) zeolites as one of the most important members of zeolitic materials, providing equally high adsorption capacity of CO 2 as aluminosilicate zeolites, can be used as promising candidate materials for selective adsorption and separation of CO 2 . In this work, desirable from both economic and environmental viewpoints, a green and cost-effective one step synthesis strategy of K-SAPO-34 zeolite was developed in a wholly inorganic system under hydrothermal conditions. The pure K-SAPO-34 crystals can be obtained in a wide range of initial gel compositions. The as-synthesized K-SAPO-34 has high proportion of framework Si (Si / (Si + Al + P) = 0.37) and framework charge density ((Al – P) / (Si + Al + P) = 0.36). Because the presence of silica islands in K-SAPO-34 framework leads to a decrease in the number of extra framework cations per unit cell, the K-SAPO-34 in this work has a high CO 2 adsorption capacity (64.1 cm 3 /g) than the conventional K-SAPO-34 prepared by ion-exchange (1.9 cm 3 /g). Moreover, the K-SAPO-34 in this work has a superior separation performance for CO 2 /N 2 and CO 2 /CH 4 .
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
FUEL
·
2013
·
IF 3.357
Anqiu Liu,Bing Liu,Yimei Wang,Rongshen Ren,Zehui Zhang
Synthesis of 5-ethoxymethylfurfural (EMF) from the etherification of 5-hydroxymethylfurfural (HMF) and the dehydrative etherification of fructose over K-10 clay supported dodecatungstophosphoric acid (abbreviated as K-10 clay-HPW). 30% wt.% K-10 clay-HPW was found to be the efficient and robust catalyst for the synthesis of EMF. The highest EMF yield of 91.5% was obtained from HMF after 10 h at 100 °C. Further more, the catalyst also showed high catalytic activity for the dehydrative etherification of fructose with EMF yield of 61.5%. The reaction work-up is very simple and the catalyst could be reused several times without the significant loss of its catalytic activity.
研究领域:
化学工程
·
可再生资源转化
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）