INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Wanbing Li,Xiaoyu Jiang,Bolong Fang,Haoze Li,Chao Chang,Jine Wu
The aim of this study was to develop and evaluate hollow sodium chloride microspheres with enhanced salinity perception as a strategy to reduce overall salt intake in foods. This experimental systematically evaluated the water content, hygroscopicity, particle size distribution, conductivity, scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and electron tongue of hollow salt microspheres prepared from hydroxypropyl-β-cyclodextrin (HP-β-CD), soluble soybean polysaccharide (SSPS), maltodextrin (MD), gum arabic (GA), and β-glucan (β-glucan). The results showed that there were significant differences in the characteristics of hollow sodium chloride microspheres prepared by different carriers. The salt microspheres prepared with HP-β-CD as the carrier exhibited low water content (1.89 %), anti-hygroscopicity (1.67 g/100 g), and fast solubility. The conductivity test results showed that the release rate of sodium ions in the salt microspheres prepared with HP-β-CD was nearly six times higher than that of ordinary sodium chloride, which could rapidly evoke the perception of saltiness. EDS analysis further confirmed that the salt microspheres prepared with HP-β-CD carrier had a higher sodium chloride content on the surface (26.25 %), thus contributing to enhancing salty taste perception. In addition, the salt microspheres prepared with soybean-soluble polysaccharide as the carrier showed a perfectly spherical hollow structure, and the caking property was lower than that of the other salt microspheres. The results of the electronic tongue analysis showed that the salt microsphere solution prepared using soybean-soluble polysaccharide had a stronger salty taste perception ability. In summary, the hollow salt microspheres prepared using HP-β-CD and SSPS showed outstanding advantages in salt taste perception properties. In the later stage, the compound ratio between the carriers will be studied, which provides a new technical reference for the salt reduction strategy of the food industry.
研究领域:
食品科学
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材料科学
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DOI
PubMed
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2018
·Vol. 18
·期 12
·8201-8206
·
IF 1.354
Ding Xu,Zhu Geng,Guan Jian-Ning,Han Guo-Zhi
In this paper, we first report the selective reduction of nitro group in aryl halides catalyzed by silver nanoparticles modified with β-CD. Taking advantage of hydrophobic lumen and donor–acceptor behavior of β-CD, the halogenated alkyl groups on the aromatic
ring can be enveloped in the inner cavity that thereby inhibits the reduction of the halogen. For validating the mechanism proposed by us, different silver nanoparticles were applied in parallel experiments. In our experiments, UV-vis spectra and NMR spectra were used to characterize the selectivity.
This strategy represents an outstanding improvement on the synthesis of halogenated aromatic amines in comparison with the traditional route, and greatly expands the application of silver nanoparticles in catalytic field.
研究领域:
化学
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材料科学
·
催化反应
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PubMed
高影响因子
REVIEWS ON ADVANCED MATERIALS SCIENCE
·
2022
·Vol. 61
·期 1
·138-145
·
IF 5.028
Yong Guo,Minghu Nie,Yingjie Wang,Zhen Zhong,Yunfeng Liu
Adsorbent is an important waste water-based drilling fluid treatment agent, which can adsorb and settle heavy metal ions, high polymer organics, and other soluble harmful substances in the waste drilling fluid. Traditional adsorbents such as polyaluminum chloride and polyacrylamide will produce other metal ions or toxic monomers after hydrolysis, which cannot fully meet the requirements of safety and environmental protection. Therefore, a new environmentally friendly waste water-based drilling fluid adsorbent, named RH-β-CD, was prepared by the Wilson etherification reaction, which was initiated by epichlorohydrin and ceric ammonium nitrate, and successfully grafted rhamnolipid and amine strong adsorption groups onto β-cyclodextrin. The adsorption effect and environmental protection performance of RH-β-CD on the organic matter and chromium ion in waste sulfonated water-based drilling fluid were evaluated and compared with commonly used adsorbents such as activated carbon, PAM, and polyaluminum chloride. The results show that RH-β-CD can effectively adsorb the organic matter in the filtrate of waste water-based drilling fluids, reduce its chemical oxygen consumption, and reduce the concentration of heavy metal ions in the filtrate. The effect is better than PAM, activated carbon, and polyaluminum chloride, with the BOD 5 /COD cr >20% and EC 50 >1,000,000 mg·L −1 , which is environmentally friendly.
研究领域:
环境科学
·
化学工程
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DOI
高影响因子
MACROMOLECULES
·
2023
·
IF 5.5
Xiangbin Sun,Peng Cao,Xue Bai,Yufeng He,Pengfei Song,Rongmin Wang
Bacterial infections have emerged as the primary adversary, causing severe health complications and incalculable economic losses. To tackle this issue, it is imperative to develop novel and highly effective antimicrobial agents. In this study, a series of double-armed antibacterial polymers (CD-QPS) were synthesized via Steglich esterification and reversible addition–fragmentation chain transfer polymerization (RAFT) polymerization. Notably, this represents a significant breakthrough in the field of antibacterial polymers derived from the quaternary phosphonium salt ionic liquid (QPSIL) and β-cyclodextrin (β-CD) via RAFT polymerization. Leveraging the controllable polymerization degree offered by RAFT and the functional group density resulting from its three-dimensional topological structure, CD-QPS exhibited exceptional antibacterial activity against Escherichia coli and Staphylococcus aureus with bacteriostatic rates reaching 100 and 99.9%, respectively. What is even more exciting is that CD-QPS demonstrated minimum inhibitory concentrations (MICs) as low as 20 μg mL–1 for E. coli and 40 μg mL–1 for S. aureus, surpassing those reported for other antibacterial materials as well as the standard drug ampicillin (32/62.5 μg mL–1). Furthermore, preservation tests conducted on oranges confirmed that CD-QPS exerted long-term antibacterial effects for an astonishing duration of 14 days. Additionally, the cytotoxicity test verified good biocompatibility of CD-QPS. In brief, we not only provide a new strategy for constructing double-armed polymers known as CD-QPS but also introduce a novel antimicrobial agent with high efficiency and long-term performance.
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高影响因子
Coatings
·
2019
·Vol. 9
·期 7
·421
·
IF 2.33
Lei Peng,Musong Lin,Sheng Zhang,Li Li,Qiang Fu,Junbo Hou
A self-healing coating with UV-shielding property was prepared in this paper. The self-healing property was based on the inclusion between a host (β-CD-TiO2) and a guest HEMA-Ad). After inclusion of the host and guest, the host–guest complex (HEMA-Ad/β-CD-TiO2) was polymerized with other reactive monomers (HEMA and BA) to obtain the final coating. The coating had good hydrophobicity (water contact angle >90°, moisture absorption rate <2%) and excellent UV-shielding performance (ultra-violet protect factor >90%), and could be firmly bonded to a soft substrate. In addition, the coating had good self-healing property, which means that cracks in the material can recover many times after being damaged and that the UV-shielding ability can be fully restored with the self-healing process.Keywords:coating;self-healing;UV-shielding;host–guest
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
Journal of Materials Chemistry B
·
2015
·Vol. 3
·期 37
·7417-7426
·
IF 4.726
Lei Xu,Wenyan Zhang,Haibo Cai,Feng Liu,Yong Wang,Yun Gao,Weian Zhang
A light-controlled porphyrinic photosensitizer release system was developed based on host–guest TPP–Azo/PEG–β-CD supramolecular amphiphiles, which could significantly enhance the efficiency of photodynamic therapy. TPP–Azo was prepared via esterification between TPP and Azo derivatives, and further used to construct supramolecular amphiphiles with PEG–β-CD. TEM images showed that TPP–Azo/PEG–β-CD amphiphiles can self-assemble into spherical micelles, and then disaggregate under irradiation with 365 nm UV light. The phototoxicity and bio-distribution of TPP–Azo/PEG–β-CD micelles against the MCF-7 cell line were also evaluated by MTT assay, flow cytometry and confocal scanning laser microscopy, respectively. According to MTT assay, the IC50 of the spherical micelle was 31.2 μg mL−1, but it became 20.6 μg mL−1 upon pre-irradiation with 365 nm UV light. This shows for the first time that UV light can well stimulate the release of porphyrin photosensitizers and improve the photodynamic therapy efficiency based on the system of host–guest supramolecular amphiphiles.
研究领域:
生物化学
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药理学
·
肿瘤学
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PubMed
高影响因子
FIBERS AND POLYMERS
·
2021
·Vol. 23
·期 2
·343-351
·
IF 2.153
Zhang Ruquan,Lei Min,Hu Bingyu,Tu Hu,Hu Min
A preparation method of compound foam dressing with antibacterial effect is introduced in this paper. Garlic oil, a natural antibacterial agent was coated with β-CD to form the garlic oil/β-CD microcapsule (MC). Then the microcapsule was added to the spinning solution with polyvinyl alcohol (PVA) and chitosan (CS) and was spun onto foam dressing to prepare garlic oil/CS/PVA nanofiber/foam compound dressings. The addition of garlic oil/β-CD microcapsule endowed the compound foam dressing with good antibacterial properties. The results shown that with the increase of MC, the antibacterial activity of compound dressing was further increased. MC 1.6 displayed the best antibacterial ability against E. coli and S. aureus (67.28 and 69.15 %), respectively. The liquid absorption properties increased from 16.86% to 17.91 % and the moisture content increased from 3.26 % to 5.29 %, compared to that of foam dressings. The mechanical properties of garlic oil/CS/PVA nanofiber/foam compound dressings increased by 4.6 N mm −2 compared with the foam compound dressings, and the elongation at break increased by about 11.3 %.
研究领域:
材料科学
·
生物医学工程
·
微生物学
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DOI
高影响因子
JOURNAL OF FOOD SCIENCE
·
2025
·Vol. 90
·期 2
·e70056
·
IF 3.4
Yihan Wang,Kai Wang,Xiaofeng Xiang,Shuming Zhang,Jie Huang,Chunhong Tang,Qiang Wang
The high cholesterol content of beef tallow is one of the potential risks affecting the nutritional value and safety of beef tallow hotpot. In this study, a novel pectin-crosslinked β-cyclodextrin (β-CD) complex was successfully prepared by the cross-linking method to reduce the cholesterol content in beef tallow. When 3% (by mass of beef tallow) of the pectin-crosslinked β-CD
complex was added, the removal rate of cholesterol in beef tallow reached 73.43%, which was significantly higher than that of the currently known materials, including β-CD. Moreover, the indexes such as fatty acid composition, chromaticity, and aroma components of beef tallow before and after cholesterol removal were measured. The results showed that the fatty acid composition and chromaticity value of beef tallow treated with the pectin-crosslinked β-CD complex did not change significantly, but the contents of aromatic components, aldehydes, ketones, and alcohol flavor compounds in beef tallow increased significantly. Through characterization experiments, it was confirmed that compared with β-CD, the pectin-crosslinked β-CD complex required a higher temperature to reach the maximum thermal decomposition rate, indicating that its structure had higher thermal stability and could effectively remove cholesterol under high-temperature conditions. In addition, after the nematode toxicity experiment, there was still a survival rate of 97.97%, indicating that the pectin-crosslinked β-CD complex could effectively reduce the cholesterol content in beef tallow without toxicity. These results suggest that the pectin-crosslinked β-CD complex has great potential as an adsorbent for removing cholesterol from animal fats and oils in the food industry.
研究领域:
食品科学
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生物化学
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DOI
PubMed
高影响因子
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2013
·Vol. 169
·期 6
·1811-1821
·
IF 1.893
Wang Ting,Li Bin,Lin Li
A novel functional material of β -cyclodextrin ( β -CD) grafting cellulose beads containing immobilized silver nanoparticles (AgNPs) is presented in this paper. The morphology was characterized by scanning electron microscopy, energy-dispersive X-ray, and X-ray photoelectron spectroscopy. Phenolphthalein probe molecule technique was used to detect the activity of the grafting β -CD, and the results demonstrated that the deposition of AgNPs had no influence on its encapsulation ability. Acid resistance of the AgNPs on the bead material was studied by atomic absorption spectrometry. The stability of the AgNPs was enhanced due to the grafting of β -CD. Tube dilution method was applied to study the bacteriostatic effect, and the minimal inhibitory doses of the novel material against Escherichia coli and Staphylococcus aureus were 12.5 and 25 mg, respectively. The minimal bactericidal doses for the two bacteria were 25 and 25 mg, respectively.
研究领域:
材料科学
·
微生物学
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DOI
PubMed
高影响因子
International Journal of Nanomedicine
·
2023
·
IF 8
Jian Lin,Tianpeng Shi,Yi Wang,Zhiqi He,Zhixiang Mu,Xiaojun Cai,Hui Deng,Jianliang Shen,Fen Liu
Background Much attention has been paid to sustained drug release and anti-infection in wound management. Hydrogels, which are biocompatible materials, are promising tools for controlled drug release and infective protection during wound healing. However, hydrogels also demonstrate limitations in the highly efficient treatment of wounds because of the diffusion rate. In this work, we explored pH-sensitive hydrogels that enable ultra-long-acting drug release and sustained antibacterial properties.Methods We constructed a hybrid gelatin methacrylate (GelMA) system with sustainable antibacterial properties combining hyaluronic acid (HA)-coated mesoporous silica nanoparticles (MSN), which loaded host-guest complexes of chlorhexidine (CHX) with β-cyclodextrins (β-CD) (CHX⊂CD-MSN@HA@GelMA). The release mechanism of CHX was explored using UV-vis spectra after intermittent diffusion of CHX. The hybrid hydrogels were characterized, and the drug content in terms of the release profile, bacterial inhibition, and in vivo experiments were investigated.Results Except for dual protection from both hydrogels, MSN in the HA improved the drug loading efficiency to promote the local drug concentration. It showed that complicated CHX-loaded MSN releases CHX more gradually and over a longer duration than CHX-loaded MSNs. This demonstrated a 12-day CHX release time and antibacterial activity, primarily attributable to the capacity of β-CD to form an inclusion complex with CHX. Meanwhile, in vivo experiments revealed that the hydrogels safely promote skin wound healing and enhance therapeutic efficacy.Conclusion We constructed pH-sensitive CHX⊂CD-MSN@HA@GelMA hydrogels that enable ultra-long-acting drug release and sustained antibacterial properties. The combination of β-CD and MSN would be better suited to release a reduced rate of active molecules over time (slow delivery), making them great candidates for wound dressing anti-infection materials.
研究领域:
生物医学工程
·
材料科学
·
药剂学
·
伤口护理
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DOI
PubMed
高影响因子
International Journal of Polymer Science
·
2018
·
IF 1.718
Xin Wang,Pin Chen,Xiaohong Hu
The focus of nanoparticle research is on exploring its application in all kinds of field. Among these, multifunctional nanoparticle attracts increasing interest due to its fittest property and adjustable property. Herein, a multifunctional and multistage nanoparticle considering the advantage of both nanogel and pH-responsive property has been designed and synthesized in the research. The composite nanoparticle was obtained by in situ processing and polymerization technique using acetylated β-cyclodextrin and gelatin as materials. Gelatin was first encapsulated into Ac-β-CD nanoparticle in order to investigate optimal fabrication conditions of W/O/W technique. The results showed that the nanoparticle had monodisperse characteristic and coarse spherical morphology, which was influenced by factors such as PVA concentration and water/oil ratio. In further step, two-phase composite nanoparticle could be obtained by combined W/O/W technique and in situ polymerization using optimal preparative parameters of W/O/W technique. Two-phase structure could be confirmed by TEM images and DLS results. Fabrication temperature had no effect on the diameters of composite nanoparticle, but influenced the encapsulated efficiency of nanogel. Finally, composite nanoparticle showed quick pH response property at mild acid medium and no obvious cytotoxicity.
研究领域:
材料科学
·
生物医学工程
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Huasheng Lai,Gongke Li,Zhuomin Zhang
In this work, a native beta-cyclodextrin capped silver nanoparticles decorated Ti 3 C 2 T x nanosheets (Ti 3 C 2 T x -AgNPs@β-CD) surface-enhanced Raman scattering (SERS) substrate was developed by a facile one-pot method. The two-dimensional Ti 3 C 2 T x nanosheets not only acted as the supporter to load AgNPs, but also served as chemical enhancement material. Meanwhile, β-CD played a critical role in the control of morphology and size of AgNPs, and its supramolecular structure also endowed the Ti 3 C 2 T x -AgNPs@β-CD substrate with selectivity. The Ti 3 C 2 T x -AgNPs@β-CD substrate exhibited excellent sensitivity, good intra-batch and inter-batch reproducibility, and long-term stability by detecting methylene blue model molecule. Then, the substrate was applied for selective determination of erythrosin B among pigment additives via the host-guest size-matching effect. The proposed SERS method with linear range of 1−100 mg/L and detection limit of 30 μg/L could realize rapid SERS analysis of erythrosin B in dyed food samples within 15 min with recoveries of 78.1 %–113.2 %. Erythrosin B was actually found in dyed cherry with 49 mg/kg and marshmallow with 16 mg/kg, and the result matched well with that of UV–vis method. Such a robust substrate possessed great values for efficient and rapid on-site SERS analysis in food safety issues.
研究领域:
食品安全
·
分析化学
·
纳米材料科学
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DOI
高影响因子
危险品化学品经营许可证（带存储）