BIOMASS & BIOENERGY
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2026
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IF 7
Ge-liang Xie,Yu Luo,Kai-cheng Xia,Sheng-ren Li,Lujiang Xu,Zhen Fang
Aromatic amines, particularly aniline derivatives, serve as pivotal intermediates in the manufacture of dyes, pharmaceuticals, and polymers. However, their conventional synthesis remains heavily reliant on fossil feedstocks and frequently employs toxic reagents. The valorization of lignin presents a promising, renewable pathway to these valuable compounds, yet the reactivity of lignin-derived phenols varies markedly depending on their functional group substituents. Herein, a pronounced "promotion-inhibition dichotomy" is reported. Alkyl substituents substantially enhance reactivity-achieving a 44.3 mol% yield of aromatic amines from 4-propylphenol, representing a 34.7% increase over phenol. Conversely, methoxy groups exert a strong inhibitory effect in limiting the yield of aromatic amines from 4-propylguaiacol to only 11.0 mol%. Furthermore, Mo-Ga/HZSM-5 catalyst employed under NH 3 -H 2 atmosphere effectively doubled the yield of aromatic amines to 25.9 mol%. A sequential hydrodeoxygenation-amination strategy is further devised, boosting the yield to 34.1 mol%. Notably, by integrating this two-step strategy with a lignin-first biorefining approach, a 16.6 mol% of aromatic amines (based on lignin) could be achieved from birch. This study elucidates key reactivity principles in lignin valorization and demonstrates an integrated strategy that advances the sustainable production of aromatic amines from renewable biomass.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2026
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IF 4.8
Zhima Yangcuo,Xiaodan Zheng,Yajuan Zhang,Xin Yang,Xinyi Zheng,Hang Zhu,Wenhui Chen,Qihong Cai
Under alkaline conditions with sodium hydroxide (NaOH), both 1-naphthol (1-NAP) and 2-naphthol (2-NAP) transitioned from their molecular forms to ionic forms, resulting in redshifts of their fluorescence spectra. Thus, not only the interference of 2-NAP raman peak was eliminated, but the fluorescence intensity of two naphthols was also enhanced, thereby improving the selectivity and sensitivity of their analysis. Due to their structural similarity, the conventional fluorescence spectra of 1-NAP and 2-NAP overlapped and interfered with each other, precluding their simultaneous measurement without prior separation. In this study, the wavelength difference (Δλ) = 140 nm was selected for synchronous fluorescence spectrometry (SFS) scanning to simplify the spectra. However, the interference of 2-NAP on 1-NAP remained significant. So, the second-order derivative technique combined with SFS was adopted. The method that eliminated the severe interference between 1-NAP and 2-NAP and wastewater background by utilizing spectral parameters. Finally, a new second-order derivative SFS for simultaneous determination of 1-NAP and 2-NAP was first established. The detection limits were 0.0850 ng·mL −1 for 1-NAP and 0.1066 ng·mL −1 for 2-NAP, with linear ranges of 0.5–80 ng·mL −1 and 0.5–50 ng·mL −1 , respectively. Recoveries of two naphthols in wastewater were 87.53%–93.50% (1-NAP) and 89.85%–104.00% (2-NAP). The new SFS established in this research has been successfully applied to the analysis and detection of 1-NAP and 2-NAP residues in wastewater, achieving satisfactory results. It is expected to become a new routine detection method for 1-NAP and 2-NAP.
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INTERNATIONAL JOURNAL OF FOOD PROPERTIES
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2026
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IF 3.9
Nian Cao,Yubo Yang,Xiaoling Xiong,Bohan Zhang,Ping Xiang,Fan Yang
This pioneering study investigated the effects of sip volume on sensory perception and drinking comfort during the consumption of Jiangxiangxing Baijiu (JB). Six sip volumes (6, 9, 12, 15, 18, and 20 mL) were tested with 30 participants (15 males and 15 females). Results revealed gender-specific preferences: females tended to prefer sip volumes of 9–12 mL, while males were more likely to favor 18 mL. Using Temporal Dominance of Sensation (TDS) and Check-All-That-Apply (CATA) methods, it was found that oral sensations of sweetness and sauce flavor, as well as post-pharyngeal sensations of “smoothness,” “mellowness,” and “lingering aftertaste,” enhanced drinking comfort. In contrast, oral sensations of spiciness and bitterness, along with post-pharyngeal sensations of “pungency,” “thinness,” “blandness,” and “momentary aftertaste,” impaired comfort. Notably, females may place greater emphasis on oral perception, whereas males could focus more on post-pharyngeal sensations. A novel flavor analysis identified 20 key compounds that influence JB perception. The insights from this research provide valuable contributions to improving the drinking experience of JB.
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Food Chemistry-X
·
2026
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IF 8.2
Zi Ye,Xinyu Wang,Tao Wang,Chuanqi Chu,Zhijia Liu,Leilei Yu,Ming Du,Junjie Yi
p -Cresol plays a pivotal role in shaping the flavor quality of suansun . This study examined the effect of inoculating Levilactobacillus zymae KUST4216, a high p -cresol-producing strain, on the fermentation of suansun . Comparative analyses between uninoculated and inoculated fermentation revealed that both followed similar acidification patterns, but inoculated fermented suansun accumulated significantly more p -cresol (6.62 ± 4.15 mg/kg vs. 0.20 ± 0.14 mg/kg). Inoculation with L. zymae KUST4216 rapidly established microbial dominance, reshaped community succession, and promoted early sugar utilization. Genomic analysis showed enrichment in carbohydrate and amino acid metabolism and abundant CAZymes, supporting efficient precursor supply for aromatic compound biosynthesis. Transcriptomic profiling confirmed coordinated regulation that directed metabolic flux toward p -cresol synthesis. Overall, L. zymae KUST4216 drives p -cresol formation via the tyrosine pathway and stabilizes fermentation ecology, providing mechanistic insight into flavor generation and offering a strategy for enhancing the sensory quality of fermented bamboo shoots through targeted microbial inoculation.
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Surfaces and Interfaces
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2026
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IF 6
Huan Song,Le Song,Fangzhou Wu,Yonglei Xing,Xiaoyong Jin,Fang Wan,Gang Ni
Non-metal doping provides a route to tune metal sites in carbon catalysts for peroxymonosulfate (PMS) activation. Here, a phosphorus-modified N-doped carbon catalyst with an ultralow cobalt loading (Co2-P1-NC; 0.14 wt% Co) was prepared. Under optimized conditions, the Co2-P1-NC/PMS system removed phenol (Ph) within 2.5 min, with an apparent pseudo-first-order rate constant of 2.068 min −1 . Co-free NC and P-NC showed only limited activity, indicating that Co-containing sites account for most of the catalytic enhancement. Quenching tests, electron paramagnetic resonance (EPR), PMSO probing, in situ Raman spectroscopy, electrochemical measurements, and premixing experiments collectively support the coexistence of radical and nonradical routes, with high-valent Co species and interfacial electron transfer making major contributions under the tested conditions. Density functional theory calculations using representative CoN 4 and CoN 3 P models showed that P substitution made PMS adsorption more favorable (from −2.56 to −3.38 eV), whereas the calculated O–O bond length and Bader charge changed only slightly; the adsorption enhancement is therefore attributed mainly to altered geometry and interfacial electronic interactions. P modification also reduced the measured Co leaching concentration from 0.016 to 0.005 mg L −1 . The catalyst rapidly removed several phenolic pollutants, although activity declined during reuse and was inhibited by carbonate and humic acid. These results demonstrate a promising low-Co catalyst design while identifying stability and water-matrix effects as priorities for further development. Download: Download high-res image (308KB) Download: Download full-size image
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LANGMUIR
·
2026
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IF 4.4
Kang Zhou,Hai Yu,Yi Luo,Yuling Wang,Zhongping Tang,Zhiliang Jin,Shuwei Yang,Rui Dong,Ping Wen,Mingjin Fan,Bing Xu,Zhe Chen
Designing high-performance lubricants with reduced ZDDP reliance requires a systematic insight into harmonizing its antiwear function with the antioxidant role of phenolic additives, which remains an unresolved dilemma. Herein, we report a molecular reconfiguration strategy that transforms ZDDP and a novel hindered triphenolic antioxidant (CDDA) into a zinc-phenolic complex, which, in turn, engineers a hierarchical tribofilm with integrated antiwear, friction-reducing, and load-carrying functions. By combining spectroscopic, computational, and tribological analyses, it is demonstrated that zinc ions from ZDDP selectively bind with terminal phenolic −OH groups of CDDA, forming a stable Z-C complex and releasing dialkyldithiophosphoric acid. Although this transformation discounts oxidation stability, it triggers the in situ construction of a robust and hierarchical tribofilm, with a sulfur-rich “foot layer” for adhesion, a porous zinc pyrophosphate “body layer” for load-bearing, and a graphene-like carbon “head layer” for friction reduction. The resulting tribofilm delivers an 83.1% reduction in wear volume and a maximum load-carrying capacity of 900 N, outperforming individual ZDDP or CDDA formulations. This work confirms that molecular reconfiguration not only enables a drastic reduction in ZDDP reliance but also opens a new pathway for programming a tribofilm structure toward high-performance, environmentally adaptive lubrication.
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Zifan Wu,Lu Chen,Yacong Deng,Fengyu Tian,Guangzheng Sun,Yuting Qiu,Yichuan Li,Yuan Pan,Bin Liu,Bin Dong,Yongming Chai
Lignin-derived phenols, with their high energy density and rich aromatic structure, are potentially high-quality feedstocks for the production of aviation fuel-range cycloalkanes. Herein, we fabricated a Ni Mo alloy catalyst anchored on graphitic carbon nitride (g-C 3 N 4 ) coated γ-Al 2 O 3 (10Ni-5Mo/CN@γ-Al 2 O 3 ), which could completely hydrodeoxygenate various lignin-derived phenols into cycloalkanes under mild conditions. 10Ni-5Mo/CN@γ-Al 2 O 3 significantly catalyzed the hydrodeoxygenation of lignin oil at 240 °C under 3 MPa H 2 for 8 h, achieving a deoxygenation degree of 96.5 % and a high propylcyclohexane selectivity (41.8 %), and the resulting products met the requirements for aviation fuels. The study results showed that electron transfer within Ni Mo alloys and the strong interaction between g-C 3 N 4 and surface anchored Ni Mo alloys in 10Ni-5Mo/CN@γ-Al 2 O 3 facilitated the dissociation of H 2 into active hydrogen to hydrogenate the aromatic rings. Meanwhile, the formation of oxygen vacancies enhanced the adsorption and activation ability of the catalyst for oxygen-containing substrates, which was beneficial for the demethoxylation and dehydroxylation reactions. This work provides a new strategy for constructing supported non-noble metal catalysts for the hydrodeoxygenation of lignin oil into aviation fuels.
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CANADIAN JOURNAL OF CHEMICAL ENGINEERING
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2025
·
IF 1.9
Xudong Wang,Yanyang Wu,Tianyou Wang,Bin Wu,Kui Chen,Lijun Ji
M-cresol and p-cresol, typically produced as mixtures in industrial processes, are crucial chemical intermediates. However, their separation is challenging due to their similar structures and properties. ZSM-5 zeolite has shown potential as an adsorbent for separation, while the performance is yet to be improved. In this study, ZSM-5-F(x) was synthesized via hydrothermal method, incorporating F − ions during the synthesis process. The adsorption behaviour of m-cresol and p-cresol on ZSM-5-F(x) was investigated through static experiments, with ZSM-5-F(8) demonstrating the highest selectivity (9.01). Both ZSM-5-F(0) and ZSM-5-F(8) were characterized using XRD, scanning electron microscopy (SEM), and Brunauer-Emmett-Teller (BET) techniques. In addition, the introduction of F − ions increased the material's electronegativity, as demonstrated by the change in zeta potential from 53.22 to −45.93 mV. Single-component adsorption of m-cresol or p-cresol on ZSM-5-F(0) and ZSM-5-F(8) respectively were investigated in detail. The adsorption of m-cresol on ZSM-5-F(8) showed a non-monotonic phenomenon with a significant decrease after 0.06 mol/L. The thermodynamic parameters including Δ G , Δ H , and Δ S were calculated accordingly. All the values |Δ G |, |Δ H |, and |Δ S | of both components on ZSM-5-F(8) were greater than those on ZSM-5-F(0), suggesting that the introduction of F − ions facilitated the adsorption. Competitive adsorption experiments on both ZSM-5-F(0) and ZSM-5-F(8) were conducted at 298.2 K. The results indicated that the selectivity α p/m on ZSM-5-F(8) increased with increasing initial concentration and laid between 13 and 14. After seven consecutive regeneration cycles, the selectivity (α p/m ) only decreased to 13. This study suggests that ZSM-5-F(8) could be a promising adsorbent for m-cresol and p-cresol in industrial applications.
研究领域:
化学工程
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材料科学
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Siyi Kang,Yawei Yang,Jingwei Chen,Jiaqiang E
Waste printed circuit boards (WPCBs) represent a valuable resource for recovery owing to their substantial metallic content. Nonetheless, efficient metal extraction is hindered by the robust epoxy resin matrix. This study introduced a novel supercritical water (SCW)-assisted acid leaching process to achieve rapid epoxy resin decomposition and high-efficiency Cu recovery. A systematic analysis was conducted on the decomposition behavior of epoxy resin and its monomer, bisphenol A diglycidyl ether (BADGE) in supercritical water. Through product characterization, the mechanism of co-action involving hydrolysis, free radical reactions, and solvolysis during the decomposition of epoxy resin has been elucidated. Response surface methodology (RSM) was employed to optimize hydrothermal parameters for BADGE decomposition and predict optimal reaction conditions. Subsequent acid leaching of SCW-decomposed products achieved a high leaching efficiency (98.9 %) and selectivity (99.9 %) of Cu. This integrated SCW-acid leaching process offers a promising and effective solution for WPCB recycling, aligning with the dual goals of environmental sustainability and efficiency in resource recovery.
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BIORESOURCE TECHNOLOGY
·
2025
·
IF 9
Jing Cao,Peiling Liu,Fangmei Teng,Jialing Liu,Yuting Ni,Xianghui Liu,Jiali Mu,Cen Zhang
Achieving both high activity and good stability remains a challenge for the design of MoS 2 -based catalysts in the hydrodeoxygenation (HDO) reaction. Herein, a robust catalyst with single-layer CoMoS anchored on hydrophobic reduced graphene oxide (SL-CoMoS/rGO) was fabricated, which exhibited high activity, selectivity and excellent stability in the HDO of lignin-derived phenolics to arenes. Utilizing the HDO of 4-methylphenol as a probe reaction, the catalyst afforded a conversion of 98.3 % and a toluene selectivity of 99.2 % at a mild condition of 210 °C and 3.0 MPa. The superior HDO performance was ascribed to the high dispersion of MoS 2 particles, which provides a large amount of edge sites for the efficient Co decoration to form the Co-Mo-S active centers. Thus, the Mo-S bond at the edge sites was significantly weakened and the formation of sulfur vacancies was remarkably enhanced. Besides, density functional theory calculations reveal that Co-Mo-S active phase could not only favor the adsorption of 4-methylphenol but also lower the energy barrier of the rate-determining step. Moreover, no obvious deactivation was observed for SL-CoMoS/rGO after six HDO cycles. The excellent durability was benefitted from the hydrophobic surface and lowered reaction temperature, which could effectively alleviate the sulfur loss and particle sintering.
研究领域:
催化化学
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材料科学
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化学工程
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纳米技术
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绿色化学
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Zhenghui Jing,Shuai Ping,Yutong An,Jia Wang,Ke Lei,Zhaohe Niu,Xinlong Zang,Zimin Liu
Spleen is an ideal secondary lymphoid organ for initiating and amplifying tumor-specific immunity; however, suboptimal antigen delivery and immune activation cause immune tolerance, limited tumor therapeutic efficacy and undesired side effects. Herein, we designed a spleen targeted nanovaccine that can carry tumor antigens and microRNA-155 (miR155) to spleen, achieving sufficient and persistent immune responses. To encapsulate miR155, we synthesized a glutathione (GSH)-responsive cationic polymer (PADDAC) that spontaneously self-assembled with miR155 to form nanocomplexes. Afterwards, the nanocomplexes were infused with tumor cell and erythrocyte membranes, granting them the ability to carry tumor associated antigens (TAAs) and target splenic antigen-presenting cells, respectively. We found that the nanovaccine demonstrated spleen-selective accumulation and efficient cytotoxic T lymphocyte activation with protective immune memory. This significantly inhibited the growth of the primary tumor and hindered the development of pulmonary metastasis in a tumor harboring mouse model. Moreover, we generated a personalized nanovaccine, which reduced local tumor recurrence post-surgery. This study highlighted the potential of splenic targeting nanovaccine for tumor preventative and therapeutic applications.
研究领域:
纳米技术
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免疫学
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肿瘤学
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生物医学工程
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RNA递送
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药物递送
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-9
·
IF 15.7
Jia Ming-Yang,Zhou Yue-Wen,Yang Jun-Lei,Liu Qinlei,Cai Zhen-Feng
Ullmann-type coupling reactions are one of the most important transformations in organic synthesis. Achieving catalyst-free Ullmann couplings under mild conditions is crucial to extending the scope of traditional carbon-carbon and carbon-heteroatom couplings. Herein, we show that Ullmann couplings can be effectively achieved at room temperature without the need for metal catalysts in MeOH/H 2 O microdroplets. Mechanistic investigations reveal that the Ullmann reaction in microdroplets is driven by •OH radicals and involves a single-electron transfer pathway via nitrogen-centered radicals. This work not only provides fundamental insights into the •OH radical-mediated coupling reactions in microdroplets but also offers a new strategy for catalyst-free Ullmann couplings.
研究领域:
有机合成
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化学反应机理
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绿色化学
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微滴化学
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