APPLIED CATALYSIS B-ENVIRONMENTAL
·
2026
·
IF 19.7
Ximan Wang,Yanshu Chen,Dehui Bian,Sigen A,Wenyue Zhao,Yunfeng Wu,Siqi Bao,Yingchen Duan
Novel Yb-BiOI/Ce-MgAl-LDH S-scheme heterojunction boosts photo-Fenton degradation. • Substrate molecular orbitals govern the selective 1 O 2 -dominated degradation. • S-scheme heterojunction achieves 100% TC-HCl degradation within 20 min. • The system demonstrates excellent environmental adaptability and stability. • Photocatalytic mechanism elucidated via experiments and DFT calculations. Developing highly selective catalytic systems remains a grand challenge in advanced water remediation. A novel S-scheme Yb-BiOI/Ce-MgAl-LDH heterojunction was rationally designed to synergistically boost photo-Fenton degradation via targeted singlet oxygen ( 1 O 2 ) generation. Unambiguously validated by in situ XPS and density functional theory (DFT) calculations, the S-scheme charge-transfer pathway efficiently accelerated spatial carrier separation while preserving maximum redox potentials. Consequently, the composite rapidly degraded the parent tetracycline hydrochloride within 20 min and achieved a mineralization efficiency of 52.5%, exhibiting outstanding degradation performance. Crucially, mechanism studies and density functional theory analyses have demonstrated that this highly selective reaction process, driven primarily by 1 O 2 as the dominant reactive oxygen species, is essentially determined by the energy levels of the specific molecular orbitals of the substrate. Pathway elucidation, coupled with in silico predictions and empirical phytotoxicity bioassays, comprehensively confirmed the substantial reduction in intermediate ecotoxicity. Ultimately, the scientific value of this work lies in providing deep mechanistic insights into S-scheme-driven selective oxidation, offering a robust and sustainable paradigm for designing targeted detoxification systems in wastewater treatment. Download: Download high-res image (262KB) Download: Download full-size image
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OPTICS AND LASER TECHNOLOGY
·
2026
·
IF 5.2
Like Li,Shunye Huang,Yi Li,Xiaoman Chen,Qiwei Li,Hui Tang,Xuqiang Wu,Yong Zhao
Due to its narrow treatment window, the vancomycin concentration in the patient’s body needs to be monitored regularly to guide dose optimization and ensure safety and efficacy. Here, we developed a fiber-optic surface plasmon resonance (SPR) vancomycin sensor based on gold nanoparticles (AuNPs)/multiwalled carbon nanotubes (MWCNTs)/DNA aptamer synergistic modification. AuNPs can effectively enhance the local electromagnetic field and plasmon resonance effects, while MWCNTs have a strong electronic conductivity and a high specific surface area. The synergistic effect of the two can achieve dual amplification of the SPR signal, thereby improving the sensitivity. Vancomycin aptamer can specifically capture vancomycin molecules and induce spatial conformational changes, thereby increasing the effective refractive index. Experimental results confirmed that within 30 μM–400 μM, the sensitivity of vancomycin detection is as high as 0.0527 nm/μM, and the detection limit is 18.11 μM. Moreover, the vancomycin sensor exhibits excellent stability and specificity. The vancomycin sensor is low-cost, easy to use, and has the potential to be applied for rapid and accurate determination of vancomycin in clinical settings.
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Nature Communications
·
2026
·
IF 18.1
Wu Jing,Yang Jingying,Liu Qisijing,Zhang Pixian,Zheng Bowen,Liu Linyuan,An Tingtao,Wang Hao,Xu Fupei,Shen Yudi,Wang Shuo
Characterizing exercise-induced fatigue is challenging due to difficulties in monitoring biochemical and electrophysiological signals consistently. While wearable sensors able to monitor both signals are available, they struggle to maintain stable signal acquisition across exercise-rest scenarios because of significant sweat variation. Here we describe the development of a system, FatigueVisual, combining an adaptive sweat-regulating hybrid electronic textile (e-ASRHT) patch with artificial intelligence (AI) analytics to improve fatigue management. The key innovation lies in the precise regulation of the breakthrough pressure of micropores in fabric electrodes and sweat-excreting areas, allowing for accurate sweat management. This design enables efficient enrichment at an ultralow sweat rate (5.0×10 −4 ml cm −2 min −1 ) while rapidly transporting excess sweat at a rate 2533 times the human physiological limit, ensuring stable chemical-electrophysiological sensing from exercise to rest. A cloud-connected AI model, trained on over 200,000 time-resolved observations collected from 10 participants, recognizes six fatigue-related states and provides personalized exercise management via a mobile app. Validation in three participants showed 87.3% agreement with clinical assessments. The system reduced exercise fatigue by 51.8% and accelerated recovery by 48 h compared with the control group. In practice, FatigueVisual may enable intelligent sports health management.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2026
·
IF 4.1
Cui Jinggang,Chen Yan,Yue Shuang,Deng Jianbo,Zhang Wenqi,Wen Shengye,Zhao Lingbo,Zhang Rumeng,Yang Shuang,Jiang Junhong
Protein glycosylation is a major post-translational modification that regulates tumor initiation and progression; however, its dynamic modeling during multistep evolution of lung adenocarcinoma (LUAD) remains poorly understood, particularly in clinically archived tissues. Here, we established an integrated multi-omics workflow combining global proteomes, N-glycans, and site-specific intact N-glycopeptides to comprehensively characterize glycosylation in formalin-fixed paraffin-embedded (FFPE) specimens spanning four pathological stages of LUAD progression: inflammatory nodules (IN), atypical adenomatous hyperplasia (AAH), adenocarcinoma in situ (AIS), and invasive adenocarcinoma (IAC). Using optimized protein extraction, hydrophilic interaction liquid chromatography (HILIC)–based glycopeptide enrichment, and high-resolution LC–MS/MS, we achieved large-scale identification of proteins, N-glycans, and intact glycopeptides from archival clinical samples. Integrated analyses revealed progressive remodeling of site-specific N-glycosylation during malignant transformation, characterized by increased glycan branching, fucosylation, and sialylation during the transition from premalignant lesions to invasive cancer. Sialylated glycans reached their highest abundance in the premalignant AAH stage, whereas highly branched and fucosylated complex N-glycans predominated in invasive adenocarcinoma, indicating stage-dependent glycan remodeling throughout disease progression. Functional enrichment analyses linked these glycosylation alterations to extracellular matrix organization, neutrophil degranulation, and immune-associated pathways, while representative glycoproteins, including CEACAM6 and FGB, exhibited coordinated changes in protein abundance and site-specific glycoform micro-heterogeneity across pathological stages. Collectively, this study demonstrates the feasibility of deep glycoproteomic profiling using archived FFPE tissues and provides a comprehensive molecular atlas of glycosylation remodeling during LUAD progression. These findings establish a valuable resource for elucidating disease mechanisms and identifying stage-specific glycosylation biomarkers and potential glycan-targeted therapeutic candidates for early lung adenocarcinoma. Graphical
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ACS Omega
·
2026
·Vol. 11
·期 28
·41554-41564
·
IF 5.2
Li Kaina,Fu Mingjie,Jiang Lei,Luo Huixiang,Jiang Chenyu,Fang Xuehui,He Tieguang,Song Xueping,Yin Yongjun
The complex lignocellulosic
structure of sugarcane leaves
poses
a major challenge for direct composting, leading to slow degradation
and long processing cycles. To address this, efficient pretreatment
is crucial for enhancing resource recovery. In this study, a combined
potassium hydroxide (KOH) and urea pretreatment was applied to sugarcane
leaves, and its effects on feedstock composition, structural properties,
biodegradability, and cocomposting performance were systematically
investigated. Under the selected pretreatment conditions (2.5% KOH,
1.5% urea, 80 ° C, 2 h), the lignin content decreased markedly
from 17.09 to 4.67%, while cellulose was largely preserved. This led
to a substantial reduction in the lignin-to-cellulose ratio. Structural
analyses revealed increased surface roughness and porosity, attenuation
of characteristic lignin peaks, and enhanced crystallinity after pretreatment.
Prior to composting, the pretreated material was subjected to a 15-day
solid-state biodegradation test to evaluate its degradability. The
results showed that the degradation rate was 165.5% higher than that
of the untreated control. Subsequently, the pretreated sugarcane leaves
were co-composted with cattle manure. Compared to conventional composting
of untreated leaves under identical conditions, the pretreatment shortened
the maturation time by about 50% and increased the total potassium
content in the final compost by 63.6%. Furthermore, the pretreatment
promoted the conversion of organic matter into humic substances, thereby
improving compost stability and maturity. This process ultimately
enhanced the nutrient content and agronomic safety of the final product.
This study demonstrates that the combined KOH-urea pretreatment is
an effective strategy for substantially enhancing the biodegradability
of sugarcane leaves, accelerating the composting process, and producing
high-quality organic fertilizer. It thus provides a viable pathway
for the efficient resource utilization of this agricultural waste.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·124383
·
IF 7.5
Zhengyan Liu,Xiaoli Su,Jie Li,Nan Jiang,Muhammad Imran,Yunxia Chen
A plasma-catalytic system coupled with floating electrode discharge with metal foam-supported catalysts was developed for efficient toluene degradation. The influences of different transition metal oxides (Co, Mn, Ce) loaded onto Fe foam (FF) substrates on the crystal structure, surface morphology and catalytic performance were systematically investigated. Catalysts were symmetrically placed on both sides of the floating electrode. Among the investigated metal oxides, Co was found to form a uniformly distributed CoFe 2 O 4 surface layer on the FF substrate, while Mn and Ce were heterogeneously dispersed as MnO 2 and CeO 2 , respectively. All metal-loaded catalysts enhanced the discharge power of the reactor, attributed to surface charge accumulation on metal oxides. The Co/FF catalyst exhibited the highest toluene degradation efficiency, CO 2 selectivity and O 3 decomposition capability. This plasma-Co/FF system significantly reduced the O 3 concentration from 112 ppm (plasma alone) to 26.2 ppm at a specific input energy (SIE) of 232 J/L. Density functional theory (DFT) calculations suggest that Co sites in CoFe 2 O 4 possess a lower O 3 adsorption energy and higher charge density potential to a higher oxygen vacancy formation tendency, promoting O 3 activation. This study provides an understanding of the mechanistic basis for the rational design of efficient plasma-catalytic systems for toluene removal.
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Innovative Food Science & Emerging Technologies
·
2026
·
IF 6.9
Zhaoyu Wang,Weiliang Hua,Yihua Zhou,Liang Pan,Yanhong Bi,Guangfu Song
The molecular basis of deep eutectic solvent (DES)-mediated extraction of arbutin was investigated using a computational chemistry method for the first time to uncover the impressionable chemical functionality of DESs. The hydrogen-bonding interactions among hydrogen bond acceptors, hydrogen bond donors, and arbutin were investigated based on density functional theory, through electrostatic potential (ESP) distribution, molecular polarity index (MPI), independent gradient model based on Hirshfeld partition (IGMH), and atoms-in-molecules (AIM) analyses. ChCl/LA (1:3) exhibited superior extraction efficiency for arbutin among the examined DESs. The ESP distribution matching study revealed that CA, LA, Gly, and PG displayed a higher overall charge distribution compatibility with ChCl than UR. In the DES–arbutin systems, ChCl/LA (1:3) showed its strongest and most stable binding characteristic with arbutin, as evidenced by the optimal electrostatic matching and the highest MPI value with arbutin. IGMH analysis indicated that both the hydroxyl and carboxyl groups in LA endowed a stronger hydrogen-bonding interaction between arbutin and ChCl/LA compared to that between arbutin and ChCl/Gly and ChCl/UR. This was further supported by the fact that the absolute value of the interaction energy of ChCl/LA (1:3) (−30.33 kcal/mol) was higher than those of other DESs (−15.86 to −26.26 kcal/mol). Moreover, AIM analysis revealed that the highest bond critical point (BCP) electron density of ChCl/LA (1:3)–arbutin was at BCP 236 (O 1 ···H 34 O) = 0.0488 a.u., corresponding to a hydrogen bond energy of −10.1534 kcal/mol, indicating the strongest hydrogen bond interaction. These findings provide a novel molecular-scale rationale for designing effective DESs for natural-product extraction.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yixuan Jiang,Yanlin Zhao,Fan Zhao,Xiaowei Cao,Dingding Jing,Haifeng Huang,Qinglei Hang
Chiral D Au NCs capillary SERS for label-free non-invasive saliva D-Glc assay. • Sensor achieves 0.30 nM LOD, covering clinical saliva glucose ranges. • Assay finishes in 10 min with 50 μL sample, high accuracy and anti-interference. • Assay shows correlation with GOD-POD gold std. (R 2 = 0.9313) and 0.947 AUC. • It offers a promising tool for early diabetes screening and clinical translation. Early, non-invasive screening and risk prediction of diabetes are crucial for effective prevention and control, as well as for delaying the onset and progression of complications. In this study, we developed a capillary surface-enhanced Raman scattering (SERS) sensor based on chiral gold nanocubes (D Au NCs) for the non-invasive, label-free, and rapid detection of d -glucose (D-Glc) in saliva. By leveraging the chiral recognition capability and strong SERS activity of D Au NCs, the sensor specifically identifies D-Glc and significantly amplifies its characteristic Raman signals, enabling quantitative analysis in complex saliva matrices without labeling. The sensor demonstrates outstanding analytical performance, covering the clinically relevant range of salivary glucose concentrations with a detection limit as low as 0.30 nM. Based on a capillary detection platform, the assay is simple and rapid, completed within 10 min using only a 50 μL micro-sample, while demonstrating strong anti-interference capability and high detection accuracy. Clinical saliva testing showed strong correlation with the glucose oxidase-peroxidase (GOD-POD) gold standard (R 2 = 0.9313), enabling reliable discrimination between healthy individuals and diabetic patients. Receiver operating characteristic (ROC) analysis yielded an area under the curve (AUC) of 0.947, confirming its high efficacy in diabetes risk screening and strong diagnostic performance. Consequently, the D Au NCs-based capillary SERS sensor provides a promising strategy for early, non-invasive diabetes screening and prevention, possessing broad potential for clinical translation and application.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2026
·
IF 3.1
Zumin Xie,Gaobo Lou,Fanfeng Ma,Yifan Chen,Xingguo Cheng,Wending Tao,Jing Han,Qian Li,Qiang Wu
With increasing environmental awareness, developing renewable and biodegradable bio-based greases is a research priority. Herein, phosphorylated cellulose nanofibrils (PCNF) were selected as a bio-based thickener due to their renewability, excellent network-forming ability, and improved interfacial properties. However, the inherent hydrophilicity of PCNF limits its compatibility with non-polar vegetable oils. To overcome this, methyltrimethoxysilane (MTMS) was used for hydrophobic modification of PCNF, and fully bio-based greases were fabricated by combining modified PCNF (M-PCNF) with castor oil. The effects of MTMS silanization degree and M-PCNF content on the microstructure, physicochemical properties, rheology, and tribology of the greases were systematically investigated. Results show that increasing silanization degree enhances penetration, oil separation, and mechanical stability but reduces viscosity and structural strength. Increasing M-PCNF content improves thickening capacity, viscosity, structural strength, and rebuild rate. Notably, the friction coefficient of M-PCNF-based greases stabilizes at 0.04–0.06, lower than that of commercial lithium grease, demonstrating excellent friction-reducing stability. This work provides a feasible strategy for high-performance bio-based greases and offers insights into structure–property relationships relevant to cellulose-based thickener design for green lubrication.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.7
Junhao Lu,Jun Wang,Yaojin Duan,Lan Ma,Dongfeng Zhai,Ihar Razanau,Kunming Pan,Yaru Li,Saifei Pan
Designing transition metal phosphides (TMPs) with remarkable performance and high stability for hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) plays a significant role in the commercial application of water splitting. Bimetallic phosphide (NiCoP) exhibits favorable electrocatalytic activity; however, it still suffers from intrinsic limitations such as insufficient intrinsic activity, inferior electrical conductivity, and a tendency toward particle agglomeration. To address these issues, a CeO 2 modified NiCoP particle catalyst (referred to as CeO 2 -NiCoP/Ti 3 C 2 T x ) loaded on a few layers of Ti 3 C 2 Tx MXene was synthesized using an HCl/LiF etching and hydrothermal phosphorization method. The CeO 2 -NiCoP/Ti 3 C 2 T x catalyst exhibits significantly lower overpotentials (287 mV for OER and 147 mV for HER) to achieve a current density of 10 mA cm −2 . Moreover, the catalyst demonstrates outstanding durability, with 93.6% and 84.6% retention of its activity after 27 h of OER and 25 h of HER, respectively.The favorable performance of CeO 2 -NiCoP/Ti 3 C 2 T x in HER and OER can be attributed to several advantages. Few-layer Ti 3 C 2 T x enhances the electrical conductivity of the material, and its large specific surface area prevents particle agglomeration, thus improving the material stability.The -O/-OH functional groups on the surface of Ti 3 C 2 T x endow the material with strong hydrophilicity, which facilitates the full contact between active sites and the electrolyte and accelerates the mass transfer and charge transfer kinetics. CeO 2 effectively optimizes the adsorption energy of NiCoP toward hydrogen intermediates by regulating the microelectronic structure of NiCoP, thereby boosting the HER kinetics.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2026
·
IF 9.1
Zipeng Jin,Junhua Wang,Kunting Li,Taibao Xiao,Wa Gao,Lei Xu,Siqi Bao,Baiyan Li
Achieving efficient charge transfer and separation relies on constructing effective electron-transfer channels tailored to composite photocatalysts. Herein, an S-scheme heterojunction was constructed between g-C 3 N 4 and covalent triazine frameworks (CTFs) to establish a directional internal electric field (IEF). The effects of donor (D) chain extension and increased acceptor (A) number on intramolecular electron transport was conducted. DFT calculations and photoelectrochemical tests indicated that, with the stepwise structural evolution from A1-D-A1 (CTF-1) to A1-D-D-A1 (CTF-2) and further to A1-D-A2-D-A1 (CTF-Azo), the electron density within the CTFs framework gradually increased. When integrated into the S-scheme heterojunction, this concerted structural engineering created an electron-rich interface that efficiently channeled electrons to adsorbed oxygen, yielding a 1.89-fold enhancement in·O 2 − generation compared to g-C 3 N 4 . This rational design enabled 1 wt% CTF-Azo/g-C 3 N 4 to achieve 92% degradation of Levofloxacin (LVX) within 120 min under visible light irradiation and demonstrated a 2.61-fold improvement over g-C 3 N 4 along with deep mineralization. A plausible photocatalytic degradation pathway was proposed, and toxicity evaluation confirmed a reduced ecological risk of the generated intermediates. Moreover, 1 wt% CTF-Azo/g-C 3 N 4 demonstrated robust performance in various complex water systems, highlighting its practical potential. This work demonstrates that orchestrating D-A molecular motifs with S-scheme heterojunctions offers a powerful paradigm for precision electron steering toward efficient antibiotic photodegradation.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2026
·
IF 4.8
Shiqiang Sun,Chuanjun Yuan,Ming Li,Meng Wang,Guo Cheng,Ke Liang
By using naturally abundant diatomite with unique particle and porosity structures as the silica precursor, a novel green-emitting diatomite-derived Zn 2 SiO 4 :Mn phosphor has been obtained as a dual functional sensor for developing latent fingerprints, serving as a fingerprint powder and a reagent for small particle reagents (SPRs). Parameters including calcination duration, calcination temperature, molar ratio of manganese salt to zinc and manganese salts, and molar ratio of zinc and manganese salts to diatomite have been adjusted to optimize luminescent property of this phosphor. Formation mechanism has been proposed based on the change of particle morphology and mesopore structure. With respect to material synthesis, high porosity of diatomite plays a critical part in ensuring uniform doping of Mn 2+ , lowering reaction temperature, sparing inert or reducing atmosphere. Furthermore, surplus diatomite in the precursors results in basic retention of particle morphology which is favorable for latent fingerprint development. Efficient green emission centered at 525 nm of the diatomite-derived Zn 2 SiO 4 :Mn under 254 nm excitation originates from the 4 T 1 → 6 A 1 transition, making it a very capable fluorescent fingerprint powder that can suppress interferences from various surfaces, especially with the aid of 530 nm band-pass filter as an optical filter and green channel of RGB images as a digital filter. Given that the luminescence of diatomite-derived Zn 2 SiO 4 :Mn phosphor is not subject to external environment factors such as water or dissolved components, a fluorescent SPR prepared by adding a certain amount of this powder (10 mg mL −1 ) to an aqueous solution of sodium dodecyl sulfate (0.050 wt%) shows better performance compared with some commercially available SPRs. Latent fingerprints on glass sheets can be clearly visualized even if they have been immersed in water as long as 5 days. Therefore, the successful acquisition of green luminescent diatomite-derived Zn 2 SiO 4 :Mn contributes to both the synthesis of this popular green-emitting phosphor and the application of fingerprint development.
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