Foods
·
2025
·Vol. 14
·期 11
·1851
·
IF 5.1
Lin Yuan,Jianfeng Yuan,Chen Gao,Haoming Zhao,Chengye Wu,Zhong-Hua Yang
The microbial conversion of inorganic Se into bioactive organoselenium compounds represents a cutting-edge strategy for developing functional foods with enhanced nutritional value. This study introduces Lactiplantibacillus plantarum S1, a novel Se-enriched probiotic strain isolated from traditional Chinese sauerkraut, and systematically optimizes its capacity for selenite biotransformation. Critical fermentation parameters—including sodium selenite supplementation timing (2 μg/mL added at mid-log phase, 7 h post-inoculation), pH (5.0), and anaerobic cultivation duration (12 h)—were identified as key determinants of conversion efficiency. The optimized protocol achieved a 72.3% organoselenium conversion yield, producing 626.6 μg/g cellular organoselenium while maintaining probiotic viability (2.28 × 10 9 CFU/mL). Se speciation analysis demonstrated that 78.51% of intracellular Se existed in organic forms, with protein-bound Se constituting the predominant fraction (85.33%), followed by polysaccharide-associated (6.42%) and nucleic acid-linked (3.38%) species. The strain’s dual functionality as both an efficient Se bioconverter and a resilient probiotic carrier highlights its potential for nutraceutical applications. These findings not only establish a robust bioprocess for Se-enriched probiotic production but also reveal mechanistic insights into preferential Se incorporation into protein matrices. This work bridges microbial Se metabolism research with scalable functional food innovation, offering a sustainable platform for developing Se-fortified products with dual health benefits.
研究领域:
食品科学
·
微生物学
·
营养学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
·
2022
·Vol. 92
·期 8
·1534-1538
·
IF 0.779
Tao Yanzhi,Yu Xiang,Wu Sini,Nong Guangzai
Abstract Selenium is an essential trace element for human body. Flavonoids have been well characterized as antioxidant, antibacterial, anticancer, and immunomodulatory agents. Therefore, a luteolin–selenium complex has been synthesized from selenium dioxide and a flavonoid luteolin. Studies of the structure of the generated complex and mechanism of its formation have indicated that the generated complex contained two luteolin units and one selenium oxide group attached to the two sixth-position carbons of luteolin units. Conversion rate for the complex is determined to be 25.3% of the mass of luteolin, and the selenium content is 11.88% of the mass of the complex.
研究领域:
化学
·
药理学
·
营养学
✓ 已验证
DOI
高影响因子
JOURNAL OF POWER SOURCES
·
2015
·
IF 6.217
Zhian Zhang,Xing Yang,Zaiping Guo,Yaohui Qu,Jie Li,Yanqing Lai
Selenium/carbon-rich (Se/carbon-rich) core–shell composites are prepared by a one-step hydrothermal synthesis method as a cathode for rechargeable lithium batteries . The Se/carbon-rich composites are characterized and examined by X-ray diffraction (XRD), field emission scanning electron microscopy (SEM), transmission electron microscopy (TEM), and thermogravimetry (TGA) measurements. It is demonstrated from galvanostatic discharge/charge process that the Se/carbon-rich composites exhibit the discharge capacity of 558 mA h g −1 in the first cycle and maintain capacity of 181 mA h g −1 after 80 cycles at a rate of 0.5C, which is better than that of the pristine selenium. The result demonstrates that the unique core–shell structure is effective in suppressing the dissolution of polyselenides into the electrolyte and in maintaining high utilization of the active materials during the charge/discharge process. It provides a new selenium-based cathode material for rechargeable lithium batteries .
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
ORGANIC & BIOMOLECULAR CHEMISTRY
·
2025
·
IF 2.7
Fei Yuan,Yiyuan Xin,Caifeng Yuan,Zhuo Chen,Tongling Qin,Wenxia Hu,Jiahuan Duan,E Tang
A simple, exogenous-base-free, and NBS-mediated C-selenocyanation/cyclization reaction of enaminones with KSeCN under mild conditions, providing a facile route to 2-aminoselenazole products, has been developed. This efficient protocol is postulated to first undergo the NBS-oxidated polarity reversal of the reactive SeCN- anion to form N-selenocyanosuccinimide as an electrophilic selenium source, which can induce the C-selenocyanation of enaminones and enamino esters, followed by a nucleophilic cyclization promoted by in-situ yielded HBr.
研究领域:
有机化学
·
合成化学
·
硒化学
✓ 已验证
DOI
PubMed
高影响因子
Small
·
2025
·
IF 12.1
Teng Li,Jiameng Zheng,Jinwei Wu,Zhenrui Li,Anding Xu,Songping Wu,Yurong Yan
Na–Se batteries with high theoretical capacity and rich natural abundance are regarded as desirable substitutes for lithium-ion batteries in the predicament of scarce lithium resources. However, the huge volume expansion of Se and the shuttling effect of polyselenides hinder the development of Na–Se batteries. Herein, the hierarchically porous carbon encapsulated Se (Se/HPC) is successfully prepared by molten Se diffusing into the multi-scaled orthogonal channels of In-MOF derived carbon matrix. The Se/HPC realizes effective nano-confinement of Se phase and accelerates charge transfer during cycling to efficiently buffer the volume expansion of Se, which avoids the shuttling effect and promote electrochemical performance. The Se/HPC achieves admirable electrochemical performance for delivering high capacity of 465 mAh g −1 at a high current density of 50 A g −1 and 533 mAh g −1 after 2800 cycles at 10 A g −1 with 0.003% capacity decay per cycle. Density functional theory calculations demonstrate that the Se─C bond is thermodynamically and kinetically beneficial for the adsorption/diffusion of Na + . This work can inspire the further exploration of utilizing the intrinsic crystal structure of MOF to construct a hierarchically porous carbon matrix in situ as carrier for the active Se component, and provide inspiration for future construction of higher-performance electrode materials.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2016
·
IF 3.15
Hongchao Li,Di Gao,Kun Li,Mengde Pang,Senlin Xie,Rutie Liu,Jianpeng Zou
The tungsten diselenide (WSe 2 ) films with different orientation present unique properties suitable for specific applications, such as WSe 2 with a C-axis⊥substrate for optoelectronics and WSe 2 with a C-axis // substrate for electrocatalysts. Orientation control of WSe 2 is essential for realizing the practical applications. In this letter, a WSe 2 film has been prepared via rapid selenization of a magnetron-sputtered tungsten (W) film. The influence of the magnetron-sputtered W film on WSe 2 film growth was studied systematically. Scanning electron microscopy, X-ray diffractometry and high-resolution transmission electron microscopy were used to evaluate the morphology, microstructure and phase composition of the W and WSe 2 films. The substrate temperature has a significant effect on the W film phase composition, but little effect on the WSe 2 film orientation. The WSe 2 orientation can be controlled by changing the W film microstructure. A dense W film that is deposited at low pressure is conducive to the formation of WSe 2 with a C-axis⊥substrate, whereas a porous W film deposited at high pressure favors the formation of WSe 2 with a C-axis // substrate. A growth model for the WSe 2 film with different texture has been proposed based on the experimental results. The direction of selenium (Se) vapor diffusion differs at the top and side surfaces. This is a key factor for the preparation of anisotropic WSe 2 films. Highly oriented WSe 2 films with a C-axis⊥substrate grow from the dense W film deposited at low pressure because Se vapor can only diffuse into the W film from the top surface where it is converted into selenide. Highly oriented WSe 2 with a C-axis // substrate can be achieved for the porous W film that is deposited at high pressure because the nanopores provide a fast transmission tunnel for Se vapor diffusion. These findings will contribute to the controlled fabrication of WSe 2 film and provide a theoretical basis for its application.
研究领域:
材料科学
·
无机非金属材料
·
薄膜制备
·
纳米材料
·
表面科学
·
半导体材料
✓ 已验证
DOI
高影响因子
Energy Technology
·
2022
·Vol. 11
·期 11
·2200376
·
IF 4.149
Peng Xu,Decheng Zhao,Shupei Liu,Jinghui Ren,Jian Zhou,Ning Wang,Zhoulu Wang,Xiang Liu,Yutong Wu,Yi Zhang
Selenium cathodes are expected to become next-generation energy storage materials due to their high electronic conductivity and volumetric capacity. However, their commercial applications are hindered by polyselenides dissolution and low Se utilization. Herein, a biomass compound, namely lychee seed, is used as a sustainable precursor to design hierarchically porous carbon by a single-step carbonization activation method. With a unique hierarchical porous structure, the lychee seed–derived activated carbon (LSDAC) used to encapsulate selenium delivers a reversible capacity of 446 mA h g −1 at 2 C and 291 mA h g −1 at 5 C after 1000 cycles. The Se/LSDAC electrodes show the most favorable fast-charging and good cycling behavior compared to the previously reported biomass-based carbon materials. By increasing the Se area loading to 9.5 mg cm −2 , the Se/LSDAC cathode maintains an areal capacity of 3.7 mA h cm −2 (3.2 mA cm −2 areal current density) after 80 cycles. High Se loading and economical and fast-charging cathode designs in Li–Se batteries are inspired.
研究领域:
电化学储能
·
材料科学
·
纳米能源材料
·
可持续能源技术
·
先进电池技术
✓ 已验证
DOI
高影响因子
Food Bioscience
·
2024
·
IF 4.8
Furong Wang,Min Yan,Ting Zhang,Zhen Tian,Xinxin Niu,Zimeng Guo,Xian Wang,Xiaoben Li,Wei Song,Yan'e Luo,Yahong Yuan,Tianli Yue
Conversion of inorganic selenium (Se) to its organic form by Saccharomyces cerevisiae ( S. cerevisiae ) has attracted significant attention, for organic Se has higher nutritional value with less negative effects. However, the mechanism of transformation and accumulation of organic Se at the metabolic level remains unclear. We investigated the metabolic response to sodium selenite supplementation in culture medium at 0, 5, 15, and 45 mg/L in two S. cerevisiae strains using an ultra-high performance liquid chromatography-high resolution mass spectrometry-based untargeted method. In total, 455 metabolites were detected, and a separation trend was clearly observed between Se-treated groups and controls. In depth, metabolic pathways involving amino acid, nucleotide metabolism and tricarboxylic acid cycle were significantly affected. Furthermore, high inorganic-Se supplementation effectively decreased the seleno-amino acid proportion in total Se, inhibited cell growth, and decreased glutathione levels. These results provide novel insights into the Se-enrichment process of S. cerevisiae .
研究领域:
微生物学
·
代谢组学
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营养学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 7
·1418
·
IF 4.2
Xiaoli Li,Ying Li,Xueyan Wang,Rui Zhang,Jiaojiao Xue,Yi Ding,Xiuling Chu,Jianqing Su
Acanthopanax senticosuspolysaccharide–nano-selenium (ASPS-SENPS) andA. selenopanaxselenized polysaccharides (Se-ASPS) were synthesized, and their characterization and biological properties were compared. The acid extraction method was used to extract the polysaccharides ofA. selenopanax, followed by decolorization using the hydrogen peroxide method and deproteinization based on the Sevage method, and the purification ofA. senticosuspolysaccharides (ASPS) was carried out using the cellulose DEAE-52 ion column layer analysis method. AnA. senticosuspolysaccharide–nano-selenium complex was synthesized by a chemical reduction method using ASPS as dispersants. The selenization of polysaccharides fromA. selenopanaxwas carried out using the HNO3-Na2SeO3method. The chemical compositions, scanning electron microscopy images, infrared spectra, and antioxidant properties of ASPS-SENPS and Se-ASPS were studied, and they were also subjected to thermogravimetric analysis. The results indicated that the optimal conditions for the synthesis of ASPS-SENPS include the following: when ASPS accounts for 10%, the ratio of ascorbic acid and sodium selenium should be 4:1, the response time should be 4 h, and the reaction temperature should be 50 °C. The most favorable conditions for the synthesis of Se-ASPS were as follows: m (Na2SeO3):m (ASPS) = 4:5, response temperature = 50 °C, and response time = 11.0 h. In the in vitro antioxidant assay, when the mass concentration of Se-ASPS and ASPS-SENPS was 5 mg/mL, the removal rates for DPPH free radicals were 88.44 ± 2.83% and 98.89 ± 3.57%, respectively, and the removal rates for ABTS free radicals were 90.11 ± 3.43% and 98.99 ± 1.73%, respectively, stronger than those for ASPS. The current study compares the physiological and bioactivity effects of ASPS-SENPS and Se-ASPS, providing a basis for future studies on polysaccharides.
研究领域:
药学
·
生物化学
·
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ADVANCED MATERIALS
·
2024
·
IF 27.4
Binhua Zou,Zushuang Xiong,Yanzi Yu,Sujiang Shi,Xiaoling Li,Tianfeng Chen
Osteoclast hyperactivation stands as a significant pathological factor contributing to the emergence of bone disorders driven by heightened oxidative stress levels. The modulation of the redox balance to scavenge reactive oxygen species emerges as a viable approach to addressing this concern. Selenoproteins, characterized by selenocysteine (SeCys 2 ) as the active center, are crucial for selenium-based antioxidative stress therapy for inflammatory diseases. This study reveals that surface-active elemental selenium (Se) nanoparticles, particularly lentinan-Se (LNT-Se), exhibit enhanced cellular accumulation and accelerated metabolism to SeCys 2 , the primary active Se form in biological systems. Consequently, LNT-Se demonstrates significant inhibition of osteoclastogenesis. Furthermore, in vivo studies underscore the superior therapeutic efficacy of LNT-Se over SeCys 2 , potentially attributable to the enhanced stability and safety profile of LNT-Se. Specifically, LNT-Se effectively modulates the expression of the selenoprotein GPx1, thereby exerting regulatory control over osteoclastogenesis inhibition, and the prevention of osteolysis. In summary, these results suggest that the prompt activation of selenoproteins by Se nanoparticles serves to suppress osteoclastogenesis and pathological bone loss by upregulating GPx1. Moreover, the utilization of bioactive Se species presents a promising avenue for effectively managing bone disorders.
研究领域:
生物材料
·
生物医学工程
·
药理学
·
骨骼生物学
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2014
·
IF 2.726
Jie Li,Xingxing Zhao,Zhian Zhang,Yanqing Lai
A hollow carbonized polyaniline spheres/selenium (HCPS/Se) composite was prepared by a simple combination method of a self-assembly method, pyrolysis and vapor phase infusion process as a cathode material for Li–Se rechargeable batteries. The composites were characterized and examined by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, the X-ray photoelectron spectroscopy and electrochemical methods, such as cyclic voltammetry, electrochemical impedance spectroscopy and galvanostatic charge/discharge tests. The HCPS/Se composite cathode can deliver relative high capacity, high Coulombic efficiency and good cycling performance. The electrochemical results show that the HCPS/Se composite cathode exhibits an initial discharge specific capacity of 571.5 mA h g −1 and retains 298.7 mA h g −1 with high Coulombic efficiency after 100 cycles at a high rate of 0.5 C (337.5 mA h g −1 ), which are higher than that of the pristine selenium cathode. The excellent electrochemical properties benefit from the high conductivity and the hollow structures of the carbonized polyaniline spheres.
研究领域:
材料科学
·
电化学
·
能源存储
·
纳米材料
·
电池技术
✓ 已验证
DOI
高影响因子
Journal of Biobased Materials and Bioenergy
·
2020
·Vol. 14
·期 5
·657-663
·
IF 1.126
Liu Jie,Wu Lichao,Tan Yimin
Se-enriched camellia oil has received increasing attention because it can improve the Se intake of diet for Se deficiency areas and has a wide spectrum of biological effects. Six main cultivars of camellia oil in Guangxi, including Camellia oleifera cenxiruanzhi 2 (CR2), CR3,
C. oleifera xianglin 4 (XL4), XL40, C. oleifera changlin 1 (CL1), and CL210, were selected for fertilization experiment to produce Se-enriched camellia oil and investigated the effect of Se enrichment on quality. The Se content in camellia oil of six varieties was significantly increased
by Se fertilizer application. CR2 had the maximum Se content and raise ratio compared to CK, which was 0.87 mg kg−1 and fourfold, respectively. The Se contents in XL1, XL210, CR3, CL4, and CL40 improved by 2.14-, 2.77-, 3.58-, 2.56-, and 3.79-fold, respectively. Se fertilizer
reduced the acid and peroxide values and increased the squalene and tocopherol contents. The acid value decreased by 38.29%–61.30%, the peroxide value decreased by 20.66%–61.79%, the tocopherol content increased by 7.76%–32.78%, and the squalene content increased by 13.53%–77.39%.
The quality indices were significantly different among camellia oil varieties. Principal component analysis showed that CR2 obtained the highest score by comprehensive evaluation. Se fertilization, particularly for CR2 species, can significantly increase the contents of Se as well as functional
components, such as squalene and tocopherol, and thus improve the quality of camellia oil
研究领域:
植物学
·
营养学
·
食品科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）