CHEMICAL ENGINEERING JOURNAL
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2020
·
IF 10.652
Jixing Cui,Yuanyuan Shao,Haiping Zhang,Hui Zhang,Jesse Zhu
Applying silver into coatings has become a prevalent method in fabricating antimicrobial surfaces. However, the concerns about durability always exist and limit its applications. Here, a highly inhibitory, active, durable, and easy-to-use silver ions-nanosilver antimicrobial additive for powder coatings was fabricated in this study. Silver nanoparticles were chemically bonded to the Ag, Cu, and Zn-ternary ion-exchanged zeolite by α -lipoic acid, which was then encapsulated by hydrophilic polymers. The fabricated silver ions and silver nanoparticles (Ag + -AgNPs) complementary structure provides a synergistic effect. Ag + is the main antimicrobial agent, while AgNPs act as a supplementary reservoir of Ag + . As well, the formed thin layer of silver nanoparticles and hydrophilic film prolongs the release of active Ag + from zeolite, and Ag + facilitates the activation of AgNPs. The results show that this additive indicates excellent antimicrobial activity to E. coli , S. aureus , P. aeruginosa , and C. albicans , and that the coatings with the additive exhibit over 99.99% reduction rate for the tested bacteria and fungi. The coating film is able to maintain over 99% antimicrobial reduction even after 1200 repeated solution wipings, or over 30 wash cycles of artificial sweat solution, indicating high durability. Furthermore, the yellowness of the coating is not evident (Δb < 2) despite the high loading of silver, and the silver nanoparticles have little impact on gloss, haze, and distinctness of the coating film image.
研究领域:
材料科学
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微生物学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
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2013
·Vol. 89
·期 12
·1817-1824
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IF 2.504
Xianxue Li,Tareque Odoom-Wubah,Huimei Chen,Xiaolian Jing,Bingyun Zheng,Jiale Huang
BACKGROUND Biosynthesis of Ag nanoparticles (AgNPs) utilizing renewable materials and nontoxic chemicals has become highly desirable and is currently receiving tremendous attention. In this study, a facile and cellulose-based approach was developed to biosynthesize AgNPs through tandem hydrolysis of silver sulfate and cellulose under hydrothermal conditions. RESULTS Well-defined AgNPs of about 72.0 nm in size were biosynthesized with 0.30 g of cellulose at 200°C for 10 h. The particle sizes of the as-synthesized AgNPs were positively affected by the reaction temperature and time, but on the contrary were negatively affected by the amount of cellulose employed. The results from Fourier transform infrared spectroscopy showed that the cellulose-hydrolyzed products (saccharides or aldehydes) were accountable for the bioreduction of the Ag ions, and the C = O (C–O) groups in the aldehydes or saccharides played critical roles in capping the AgNPs. Additionally, in the presence of the as-synthesized AgNPs, enhanced surface fluorescence of methyl orange was achieved. CONCLUSION A biological and maneuverable strategy was successfully developed for the synthesis of AgNPs by a hydrothermal route through tandem hydrolysis of silver sulfate and cellulose. Thus, this environmentally friendly method is anticipated to be utilized for the biosynthesis of AgNPs and opens up avenues to prepare other metal nanoparticles from metal sulfates. © 2013 Society of Chemical Industry
研究领域:
材料科学
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生物学
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DOI
高影响因子
Micro & Nano Letters
·
2015
·Vol. 10
·期 12
·689-692
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IF 0.853
Jun Zhu,Xiufang Xu,Maomao Yao,Yiqun Zheng,Shifeng Hou
A facile approach to producing silver (Ag) microspheres with a porous structure via a one-pot synthesis is described. The success of this work relies on the use of Cu 2+ to mediate the reduction of silver chloride by oleylamine. The type of additives, amount of copper(II) chloride, type of Ag precursor and reaction temperature were systematically investigated to reveal their roles in the formation of the unique porous structure. The method described provides a convenient route for fabricating porous Ag micro/nanocrystals and could be potentially extended to similar synthesis of other noble metals.
研究领域:
材料科学
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化学
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产品关联
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2020
·
IF 16.683
Xueyan Chen,Honghong Wang,Min Chen,Xiaoxiao Qin,Hong He,Changbin Zhang
Ag-based catalysts are shown to be efficient for formaldehyde (HCHO) oxidation at low temperature, while the role of active Ag species in this reaction remains a controversial issue. In this work, we prepared Ag/TiO 2 catalysts with TiO 2 of different crystal structures (anatase or rutile) as supports and tested their performances in HCHO oxidation. We observed that the crystal structure of the TiO 2 support had a significant influence on the activity of the Ag/TiO 2 catalysts, and Ag/A (anatase) exhibited dramatically superior activity compared with Ag/R (rutile). More interestingly, we observed a clear inflection point in the HCHO conversion curve for the Ag/R catalyst. Combining the results of BET, XRD, TEM, XAFS, H 2 -TPR characterization and DFT calculations, we show that HCHO oxidation on Ag/TiO 2 catalysts is a co-function process of multiple active sites including surface oxygen, Ag 2 O, and metallic Ag species. The low-temperature non-renewable surface oxygen and Ag 2 O species mainly contribute to HCHO oxidation in the low-temperature range, while metallic Ag species are primarily responsible for the reaction at high temperature since metallic Ag is capable of activation of oxygen at high temperature. The relative contents of surface oxygen, Ag 2 O and metallic Ag species are different on the Ag/A and Ag/R catalysts. The dispersion degree of metallic Ag species also differs on the Ag/A and Ag/R, therefore their capacities for oxygen activation are quite dissimilar. The above factors combine to result in distinct catalytic behaviors for Ag/A and Ag/R in HCHO oxidation, as well as the appearance of an inflection point.
研究领域:
催化化学
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环境化学
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材料科学
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表面科学
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物理化学
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DOI
高影响因子
PROCESS BIOCHEMISTRY
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2020
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IF 2.952
Chang-Wei Zhang,Ming-Fei Li,Zhi-Wen Qi,Ran Tao,Jian-Zhong Ye,Xing-Ying Xue,Cheng-Zhang Wang
The aim of this work was to construct a new type of system for the green extraction and efficient separation of Ginkgo biloba leaf polyprenols (GBP). First, cell disruption technologies (enzymolysis, ultrasound, microwave and ball milling) coupled with deep eutectic solvents (DES) were used to extract polyprenyl acetates (PA) from Ginkgo biloba leaves. Results showed that ball milling was the best assisted extraction method, and the amount of PA was 89.88 mg/g. Then, a novel silver-loaded material with selectivity for PA was synthesized, characterized and utilized to absorb PA from the DES extraction solution. The purity of the PA quickly reached 71.28 % after being separated by the silver-loaded material. Finally, saponification and molecular distillation were adopted to remove non-GBP ingredients, and a high-purity GBP (99.80 %) was obtained by optimizing its processing conditions. This study provides a technical support for the development of a green and efficient GBP separation method and lays the foundation for the fabrication of GBP-based drugs, health products and cosmetics.
研究领域:
天然产物化学
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药物分离与纯化
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绿色化学
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植物化学
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分析化学
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DOI
高影响因子
CHEMOSPHERE
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2017
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IF 4.208
Zhenzhen Huang,Piao Xu,Guiqiu Chen,Guangming Zeng,Anwei Chen,Zhongxian Song,Kai He,Lei Yuan,Hui Li,Liang Hu
This study investigated the influence of silver ions (Ag + ) on the cytotoxicity of silver nanoparticles (AgNPs) in Phanerochaete chrysosporium and noted the degree of extracellular secretions in response to the toxicant's stress. Oxalate production was elicited with moderate concentrations of 2,4-dichlorophenol (2,4-DCP) and AgNPs reaching a plateau at 10 mg/L and 10 μM, respectively. Increased oxalate accumulation was accompanied by higher activities of manganese peroxidase (MnP) and lignin peroxidase (LiP). However, the secretion of oxalate, MnP and LiP was significantly inhibited owing to Ag + incorporation into AgNP solution. Production of extracellular polymeric substances (EPS) significantly elevated with an increase in 2,4-DCP concentrations; however, after 24 h of exposure to 100 mg/L 2,4-DCP, an obvious decrease in EPS occurred, indicating that part of EPS could be consumed as carbon and energy sources to ameliorate biological tolerance to toxic stress. Furthermore, AgNP-induced “particle-specific” cytotoxicity was substantially enhanced with additional Ag + as evidenced by its significant negative impact on cellular growth, plasma membrane integrity, and morphological preservation compared with AgNPs at equal Ag concentration.
研究领域:
微生物学
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环境科学
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毒理学
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DOI
PubMed
高影响因子
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
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2022
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IF 3.915
Nan Jin,Jingwen He,Chenyuan Wu,Zejun Chen,Yuling Li,Jianmin Chen,Jianhu Lin
The aim of this study was to explore the function of glycyrrhizic acid (GA) in an anti-psoriatic dermal delivery, whereby GA is originally designed as the matrix agent, with curcumin (Cur) as the active agent and silica as the drug carrier. Formulations with different GA proportions were prepared and named W-GA (without GA), L-GA (13% w/w GA) and H-GA (26% w/w GA). The results showed that GA had no significant effect on the physical characteristics, such as particle size and amorphous state, as exhibited by scanning electron microscopy and x-ray diffractograms, respectively. Compared with W-GA and L-GA, H-GA resulted in 10% less photodegradation of Cur after storage for one month, 0.45 μg more penetrated Cur in the epidermis, 2-fold higher viscosity, fewer signals of imiquimod-induced psoriasiform skin lesions and less histological morphological changes. The findings showed that H-GA significantly inhibited expression of interleukin 17 A in the dermis, and interleukin IL-23 in the epidermis, compared with Cur raw drug powder (RDP), whereas L-GA had no significant effect on the expression. These results indicated that a high GA proportion results in superior anti-psoriatic efficacy. Therefore, Cur-loaded silicas with approximately 26% GA are recommended as the superior formulation for the treatment of psoriasis.
研究领域:
药剂学
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皮肤病学
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药物递送系统
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DOI
PubMed
高影响因子
AMERICAN JOURNAL OF CHINESE MEDICINE
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2025
·Vol. 53
·期 02
·543-566
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IF 5.5
Jia-Yuan He,Fu-Lan Xiao,Qin-Yue Zheng,Chang-Hong Wang,Yi-Yue Tang,Jun-Xuan Fu,Jia-Yi Huang,Lian-Di Zhou,Qi-Hui Zhang
The intestinal absorption of active herbal constituents plays an important role in the biomedical efficacy of Traditional Chinese Medicine (TCM) formulations after oral administration. TCM compounds with low oral bioavailability can reach the distal intestine and then interact with intestinal flora, influencing the botanical pharmacological effects. In this study, in vitro digestion and an ex vivo Ussing chamber model were utilized to evaluate the intestinal absorption behavior of Forsythiae Fructus - Lonicerae Japonicae Flos -containing Yinqiao Jiedu Granule (YQJDG). It was found that the jejunum exhibited active absorption effects for some components of the formula, while the oral bioavailability of other herbal ingredients was low. Through further research using a combined UPLC-MS/MS and 16S rDNA sequencing technique, we studied the existence of the reciprocal interactions between YQJDG and gut microbiome. The in vitro fecal fermentation results showed that YQJDG significantly impacted the microbial community composition. The YQJDG markedly increased the abundance of beneficial microorganisms, such as Parabacteroides distasonis and Streptococcus gallolyticus subsp. Macedonicus, and suppressed the abundance of conditional pathogens including Prevotella steorerea, Haemophilus parainfluenzae , and Bacteroides . These effects may potentially contribute to the body’s immune functions and anti-inflammatory capacities. UPLC-MS/MS analysis suggested that the fecal microbiota chemically transformed constituents with low bioavailability to more readily absorbed potentially active metabolites. These findings provided valuable insights into the absorption characteristics of YQJDG and its interaction with the gut microbiome, further facilitating our understanding of precise pharmacological mechanisms of action of this Chinese herbal formulation.
研究领域:
中药学
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微生物学
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药理学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
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2022
·Vol. 57
·期 11
·6335-6344
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IF 4.682
Liu Lingling,Zhou Shu,Luo Liping,Zheng Jingjing,Ji Lijun
Ag@C fibres with porous silver structure were synthesized with a surface-hydrolyzed polyacrylonitrile (PAN) fibre as a template and by a hydrazine hydrate reduction and carbonization process. The composition and structure of the Ag@C fibres were characterized with a scanning electron microscope, an X-ray diffractometer, a Fourier transform infrared spectrometer, an X-ray photoelectron spectrometer, a Raman spectrometer, and a thermogravimetric analyser. The porous structure of the silver shell combined with carbon was conducive to the release of silver ions and suppressed the loss of silver nanoparticles from the surface of the carbon fibres. The Ag@C fibres showed excellent antibacterial performance. When the dosage of Ag@C fibres prepared with a silver nitrate solution of 0.5 mol/L was 1 mg, 2 mg, 4 mg and 8 mg, the bacterial inactivation rate to Staphylococcus aureus was 97.98%, 99.89%, 99.99%, and 99.99% in 12 h, respectively. The loss of viability only decreased to 80% when 1 mg of Ag@C fibres were used for antimicrobial activity test after five times of recycling. The Ag@C fibres have a broad application prospect in producing fabric products of antibacterial fields. Graphical abstract
研究领域:
材料科学
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微生物学
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DOI
高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 8
·1-8
·
IF 5.479
Mao Anqi,Wei Chunying
DNA-templated silver nanoclusters (DNA-Ag NCs) with cytosine (C)-rich sequences (four or more segments of consecutive (2–5) C-bases) were synthesized. They display green and/or orange/red emissions under different excitation wavelengths. There is indication that more consecutive C-bases lead to longer emission wavelengths. The ratio of the red and green emissions of the DNA-Ag NCs depends on whether the NCs were synthesized under acidic or basic conditions. We also prepared the DNA copper/silver nanoclusters (DNA-Cu/Ag NCs) which can be synthesized in shorter time and display higher stability. The DNA-Cu/Ag NCs, under 470 nm photoexcitation, always display green emission, with a peak at 550 nm, irrespective of whether being prepared under acidic or basic conditions. The fluorescence of the Cu/Ag NCs is selectively quenched by Hg(II) ions which can be quantified by this nanoprobe with a detection limit as low as 2.4 nM. The quenching mechanism was studied by Stern-Volmer plots and lifetime studies which revealed that both static and dynamic quenching are operative.
Schematic presentation of fluorescent DNA-Ag nanoclusters (NCs) exhibiting red and green emission under different pH values, and green emissive DNA-Cu/Ag NCs for sensitive and rapid detection of Hg 2+ .
研究领域:
生物化学
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分析化学
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纳米科学
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产品关联
DOI
PubMed
高影响因子
Royal Society Open Science
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2020
·Vol. 7
·期 1
·
IF 2.646
Tianrui Chen,Hui Yang,Shengchi Bai,Yan Zhang,Xingzhong Guo
With polyol-synthesized silver nanoparticles (AgNPs) as raw materials, the silver electrodes with high conductivity were fabricated via a dip-coating method followed by sintering process, and the effects of the dip-coating and sintering process on the conductivity and surface roughness of silver electrodes were investigated in detail. The silver film with a thickness of 1.97 µm and a roughness of about 2 nm can be prepared after dip-coating at a pulling rate of 500 µm s−1 for 40 coating times. The non-conductive dip-coated silver films are transformed into conductive silver electrodes after conventional sintering in a muffle oven, infrared sintering and microwave sintering, respectively. Compared with high sintering temperature and long sintering time of conventional sintering and infrared sintering, microwave sintering can achieve quick sintering of silver films to fabricate high conductive silver electrodes. The silver electrodes with a sheet resistance of 0.75 Ω sq−1 and a surface roughness of less than 1 nm can be obtained after microwave sintering at 500 W for 50 s. The adjustable dip-coating method followed by quick microware sintering is an appropriate approach to prepare high conductive AgNPs-based electrodes for organic light-emitting diodes or other devices.
研究领域:
材料科学
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电子工程
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产品关联
DOI
PubMed
高影响因子
Electronic Materials Letters
·
2015
·Vol. 11
·期 4
·702-706
·
IF 1.98
Han Wen-Song
In this manuscript, the third-generation hyperbranched polyester was synthesized with 2, 2-dimethylol propionic acid as AB 2 monomer and pentaerythrite as core molecule by using step by step polymerization process at first. Then, the Cu-Ag particles were prepared by co-reduction of silver nitrate and copper nitrate with ascorbic acid in the aqueous solution using hyperbranched polyester as template. Finally, the Cu-Ag@Ag particles were prepared by coating silver on the surface of Cu-Ag particles by reduction of silver nitrate. The synthesized hyperbranched polyester and Cu-Ag@Ag particles were characterized by Fourier transform infrared (FT-IR) spectroscopy, UV-vis spectra, x-ray diffraction, Laser light scattering, thermogravimetric analysis (TGA) and SEM. UV-vis spectra results showed that the Cu-Ag@Ag particles had a strong absorption band at around 420 nm. Laser light scattering and SEM studies confirmed that the most frequent particle sizes of Cu-Ag@Ag particles were 1.2 um. TGA results indicated that the Cu-Ag@Ag particles had good thermal stability.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）