JOURNAL OF SOLID STATE CHEMISTRY
·
2024
·
IF 3.2
Bin Duan,Changchun Ding,Mengjia Zhang,Yuxiang Wu,Yongqiang Li,Wei Jin,Fengyi Wang,Junshan Hu
Exploring novel oxysalt compounds remains significant due to their affordability and versatile applications, such as serving as laser crystals, piezoelectric crystals, frequency-doubling crystals, and luminescent materials. Specifically, this study introduces a new near-single green upconversion luminescent Ca 9 (VO 4 ) 7 : Yb 3+ /Er 3+ material, synthesized through high-temperature solid-phase methods. When subjected to 980 nm near-infrared laser irradiation, the Ca 9 (VO 4 ) 7 : 0.3 Yb 3+ , 0.02 Er 3+ phosphor demonstrates robust green luminescence at 531 nm ( 2 H 11/2 → 4 I 15/2 ) and 558 nm ( 4 S 3/2 → 4 I 15/2 ), accompanied by faint red luminescence at 665 nm ( 4 F 9/2 → 4 I 15/2 ). The optimal doping concentrations for Yb 3+ and Er 3+ ions, yielding the highest upconversion luminescence intensity, are determined to be 0.3 and 0.02, respectively. The investigation elucidates the upconversion luminescence mechanism through the downward shift spectrum in photoluminescence and the pumping power dependence of upconversion green-red luminescence. The primary excitation pathway identified for the upconversion process in Ca 9 Y(VO 4 ) 7 : 0.3 Yb 3+ , 0.02 Er 3+ involves Yb 3+ ( 2 F 5/2 ) + Er 3+ ( 4 I 11/2 ) → Yb 3+ ( 2 F 7/2 ) + Er 3+ ( 4 F 7/2 ). This research contributes to the exploration of new materials, injecting vitality into modern industries and production processes.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2025
·
IF 4.3
Hanyu Jiang,Xuanjun Wang,Siyu Xu,Jin Yu,Zihao Zhang,Xiaogang Mu,Taizhong Huang,Fengqi Zhao
The 1,1-diamino-2,2-dinitroethylene (FOX-7) has been adopted in high-energy explosives. To further improve the thermal safety and detonation performance of FOX-7, a microfluidic crystallization platform with a swirl-shaped chip was employed to prepare ultrafine FOX-7. Results show that the crystal structure of FOX-7 could be precisely controlled by adjusting the operational parameters of microfluidic. The microfluidic techniques prepared superfine FOX-7 exhibit a consistent smaller particle size, narrower particle size distribution, reduced crystal defects, and enhanced sphericity structure. On the other hand, the thermochemical properties of FOX-7 are also improved. The thermal decomposition temperature and critical thermal explosion temperature of ultrafine FOX-7 are increased by 24.6 and 22.1 °C, respectively. The thermal stability, energy release efficiency, and combustion of the microfluidic recrystallization method prepared FOX-7 are greatly improved. This research presents a secure, effective, and eco-friendly methodology for the preparation and manipulation of ultrafine FOX-7 crystals.
研究领域:
材料科学
·
化学工程
·
爆炸物研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Healthcare Materials
·
2018
·Vol. 8
·期 2
·1801458
·
IF 5.609
Haishi Qiao,Jing Jia,Wei Chen,Bin Di,Oren A. Scherman,Chi Hu
The fabrication, characterization, and therapy efficiency of a noncovalent-bonded hydrogel network, which is assembled by utilizing cucurbit[7]uril as a supramolecular linker to “stick” superparamagnetic γ-Fe 2 O 3 nanoparticles onto the polymer backbone of catechol-functionalized chitosan are described. The unique barrel-shaped structure of cucurbit[7]uril not only facilitates host–guest recognition with the catechol derivatives, but also forms robust electrostatic interactions between its carbonyl portals and the γ-Fe 2 O 3 nanoparticles in a supramolecular manner, which leaves the physical and chemical properties of the nanoparticles intact. The γ-Fe 2 O 3 nanoparticles display vibrational movement and heat generation under an alternating magnetic field, endowing the formed hybrid supramolecular hydrogel with both thermo- and chemotherapy modalities, which are demonstrated both in vitro and in vivo. Here, a facile strategy is introduced to construct noncovalent interactions between a polymer matrix and the incorporated nanoparticles, which is amendable to a wide range of biomedical and industrial applications.
研究领域:
生物材料
·
纳米医学
·
肿瘤治疗
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2020
·Vol. 138
·期 20
·50424
·
IF 2.52
Junfeng Qian,Tingting Wu,Jianqun Shi,Hao Chang,Donghui Liu,Yichang Pan
Membrane-based technology is an attractive alternative in terms of CO 2 separation. Pebax-based membranes are regarded as potential candidates for CO 2 separation due to the favorable interaction between its poly (ethylene oxide) chains with CO 2 molecules and inorganic fillers. However, the separation performance for CO 2 /CH 4 mixture is still suffered from the moderate gas permeability and selectivity. To overcome this problem, in this work, amino-functionalized zeolite imidazolate framework (ZIF-7-NH 2 ) nanocrystals were used as fillers to blend with Pebax 1657 for fabricating mixed-matrix membranes (MMMs). XRD, Brunauer–Emmett–Teller (BET), scanning electron microscope, and 1 H nuclear magnetic resonance characterization indicated that ZIF-7-NH 2 with the highest crystallinity was synthesized. Fourier transform infrared spectroscopy, thermogravimetric analysis, differential scanning calorimetry (DSC), and Young's modulus showed that it has good interfacial interaction. Gas separation test results showed that both the CO 2 permeability and CO 2 /CH 4 selectivity of the 31 wt% ZIF-7-NH 2 /Pebax MMMs increased by 80 and 170%, respectively. The improved performance is attributed to the addition of ZIF-7-NH 2 nanocrystals and the favorable interfacial interactions between the polymer and ZIF-7-NH 2 nanocrystals. Furthermore, the polyvinylidene fluoride supported hollow fiber composite membranes also exhibit the long-term stability for CO 2 /CH 4 separation.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
BRITISH JOURNAL OF NUTRITION
·
2023
·
IF 3.6
Fan Du,Min Yan,Lili Duan,Guolong Xie,Xiuhua Yao,Wenjing Hu,Yu Liu,Min Meng,Jiepeng Chen,Di Shao
Menaquinone-7 (MK-7), a multipotent vitamin K2, possesses a wide range of biological activities, a precise curative effect and excellent safety. A simple and rapid LC-APCI-MS/MS method for the determination of MK-7 in human plasma with single liquid–liquid extraction (LLE) extraction and 4·5-min analysis time has been developed and validated. Four per cent bovine serum albumin (BSA) was used as surrogate matrix for standard curves and endogenous baseline subtraction. This method was reproducible and reliable and was used to analyse of MK-7 in human plasma. The endogenous circadian rhythm and bioavailability of MK-7 were investigated in two randomised single-dose, open, one-way clinical trials (Study I and Study II). A total of five healthy male subjects were enrolled in Study I and 12 healthy male subjects in Study II. Single-dose (1 mg) of MK-7 was given to each subject under fasting condition, and all eligible subjects were given a restricting VK2 diet for 4 d prior to drug administration and during the trial. The experiment results of Study I demonstrated that endogenous MK-7 has no circadian rhythm in individuals. Both studies showed MK-7 are absorbed with peak plasma concentrations at about 6 h after intake and has a very long half-life time.
研究领域:
药理学
·
营养学
·
临床研究
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2019
·
IF 5.108
Kangmeng Zhu,Xisong Wang,Dong Chen,Wei Ren,Heng Lin,Hui Zhang
Wood-based biochar, as a metal-free heterogeneous activator of peroxydisulfate (PDS), was successfully prepared by pyrolysis of polar sawdust for efficient removal of Acid Orange 7 (AO7). The results demonstrate PDS could be effectively activated by wood-based biochar, and AO7 was rapidly eliminated in a wide range of pH value (3.0–10.0) with AO7 removal achieved ≥ 99.3% after 14 min reaction. The dominant reactive species in the biochar/PDS system were verified via radical quenching tests and electron paramagnetic resonance (EPR) technique. It is speculated that sulfate radicals (SO 4 •− ) and hydroxyl radicals ( • OH) were formed on the surface of biochar. Based on the results of X-ray photoelectron spectroscopy (XPS), π-electron density and oxygen-containing functional groups (especially C–OH) on biochar surface were active centers for the catalytic reaction. Recycle experiments of biochar for 4 runs were carried out and the regeneration method of the catalyst was also studied.
研究领域:
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
Sugar Tech
·
2021
·Vol. 24
·期 3
·832-840
·
IF 1.591
Yang Yujiao,Zheng Rui,Zhang Pingling,Wen Jing,Luo Yue,Zhao Zhengang,You Lijun,Ho Chi-Tang
Sugarcane is one of the most important crops in the world and rich in polyphenols. In this study, quercetin, apigenin, luteolin, tricin and p -coumaric acid, the major polyphenols in sugarcane, were used to evaluate the antiproliferative activities toward MCF-7 human breast cancer cells independently and in combination. These five polyphenols all showed inhibitory effects against MCF-7 cells within different dose ranges. The combinations of luteolin and three polyphenols (quercetin, apigenin, p -coumaric acid) were studied. p -Coumaric acid together with luteolin exhibited synergistic effects at all concentrations tested: the CI (Combination Index) values at 50%, 75% and 90% inhibition of MCF-7 cell growth were 0.68 ± 0.06, 0.70 ± 0.08 and 0.83 ± 0.09, respectively. Although the two-way combination of luteolin and apigenin showed moderate antagonistic effect (CI, 1.26 ± 0.24) at EC 50 , the CI value dropped as the inhibition rate increased, showing a synergistic effect at the inhibition rate above 70%. The combination of luteolin and quercetin indicated antagonistic effect at the inhibition rate above 50% (Fa 0.5, CI = 1.10 ± 0.05). p -Coumaric acid with quercetin exhibited antagonistic actions (Fa 0.5, CI = 1.62 ± 0.22) at all concentrations tested. In addition, the EC 50 values of luteolin and quercetin against MCF-7 cells decreased by 1.91 and 2.62-fold after combining with 20 µM tricin. The results provide evidence of synergistic relation among polyphenols present in sugarcane in inhibition of cancer cell growth and of their potential clinical application.
研究领域:
肿瘤学
·
植物化学
·
药理学
✓ 已验证
DOI
高影响因子
LIFE SCIENCES
·
2019
·
IF 3.448
Enxia Zhang,Jiasi Liu,Lei Shi,Xin Guo,Ze Liang,Jiaxin Zuo,Hong Xu,Huaxin Wang,Xiaohong Shu,Shanshan Huang,Shubiao Zhang,Xiaohui Kang,Yuhong Zhen
Aims To investigate the effect of 7- O -geranylquercetin (GQ), a derivative of quercetin (Q), on reversing drug resistance in breast cancer MCF-7/ADR cells and reveal the mechanisms related to P-glycoprotein (P-gp). Main methods Cell viability was determined by MTT assay. Accumulation of adriamycin (ADR) in cells was determined by confocal fluorescence microscope and microplate reader while that of rhodamine (Rh) was measured by flow cytometry. Expression levels of P-gp and MDR1 gene in cells were detected by western blot and Real-Time PCR, respectively. Molecular docking of GQ and Q with P-gp was conducted using AutoDock program. Xenograft model was established by inoculating MCF-7/ADR cells in BALB/c-nude mice. Tumor bearing mice were administered with ADR via tail vein injection and/or GQ (Q) by gavage. Expression levels of P-gp in tissues were detected by western blot and immunohistochemistry. Key findings GQ could reverse drug resistance of MCF-7/ADR cells to ADR. GQ inhibited the efflux of ADR by down-regulating the expression of P-gp protein and its encoding gene MDR1 in MCF-7/ADR cells. Molecular modeling showed that GQ matched with P-gp better than Q. GQ enhanced the antitumor effects of ADR and decreased the expression of P-gp in mice and its activities were higher than that of Q. GQ could reverse drug resistance of MCF-7/ADR cells by down-regulating the expression of P-gp in vitro and in vivo. Significances The reversal effect of GQ on P-gp-mediated drug resistance indicates its potential as a reversal agent for drug resistance in cancer chemotherapy.
研究领域:
肿瘤学
·
药理学
·
分子生物学
✓ 已验证
DOI
PubMed
高影响因子
WATER AIR AND SOIL POLLUTION
·
2016
·Vol. 227
·期 10
·1-8
·
IF 1.551
Li Ying,Yang Lijiao,Chen Cheng,Lan Yeqing
In this paper, Zn(0)-catalyzed ozonation degradation of acid orange 7 (AO7) and its impact factors including solution pH, Zn loading, and AO7 initial concentration were investigated through a series of bath experiments. The results demonstrated that Zn could markedly accelerate the degradation of AO7 by ozone (O 3 ) and the degradation efficiency of AO7 increased by 77 and 71 % within 30 min as compared with those in the systems of O 3 alone and Zn/air, respectively. The reuse of Zn resulted in a slight decline in AO7 degradation, suggesting that a coating of ZnO on the surface of Zn particles weakened Zn catalytic activity. The optimal removal of AO7 was achieved in a wide pH range of 4 to 10, and a lower or higher pH was not conducive to the degradation of AO7. In addition, the degradation efficiency of AO7 increased with Zn loading but decreased with AO7 initial concentration. The introduction of free radical scavengers into the system of AO7/Zn/O 3 confirmed that O 2
•− , rather than •OH, was the main free radicals responsible for the rapid removal of AO7. The degradation of AO7 by O 3 assisted with Zn could be well expressed with pseudo-first-order kinetic model.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Journal of Flow Chemistry
·
2023
·Vol. 13
·期 4
·375-383
·
IF 2.7
Lai Liangchuan,Gao Liang,Liu Minjie,Guo Yongxing,Cheng Dang,Jiang Meifen,Chen Fener
Continuous flow technology has been widely adopted in manufacturing active pharmaceutical ingredients (APIs). Herein, we report an expeditious multi-step continuous-flow strategy for an efficient and highly productive flow synthesis of 7-methoxy-1-tetralone, which is an essential intermediate for the opioid analgesic drug (-)-dezocine. Compared with the traditional batch operation, this work presents significant advantages of continuous-flow chemistry with dramatically reduced reaction time, highly improved reaction efficiency, good controls over reaction optimizing conditions, etc. The flow protocol in this work provided the desired product in an overall yield of up to 76.6% with 99% purity, much higher than those from batch process (i.e., 50% yield, 92% purity). Moreover, reaction efficiency is highly improved with a throughput of 0.49 g/h, the total reaction time is markedly reduced from hours in batch to minutes in flow process. Graphical abstract
研究领域:
有机化学
·
制药工程
·
药物合成
✓ 已验证
DOI
高影响因子
OPTICAL MATERIALS
·
2022
·
IF 3.754
Shasha Feng,Jingjing Lv,Fubin Pei,Yi Wu,Qingli Hao,Zhaoyang Tong,Wu Lei,Guangyu He
A highly selective fluorescence sensor based on boron and nitrogen co-doped carbon quantum dots (BN-CDs) was firstly constructed for the determination of 1,1-diamino-2,2-dinitroethylene (FOX-7). The BN-CDs fluorescent probe was prepared by a simple, green, and low-cost one-pot hydrothermal carbonization method. The BN-CDs with good dispersion had strong fluorescence property, and the particle size was about 3 nm. The Fourier transform infrared spectrum and X-ray photoelectron spectroscopy showed that B and N elements were successfully co-doped into CDs. Under the optimal experiment condition, BN-CDs fluorescent probe had a good linear relationship with the concentrations of FOX-7 in the range of 0–80 μM, and the limit of detection was 0.41 μM. The fluorescence of BN-CDs decreased with the increase of FOX-7 concentration, which was ascribed to inner filter effect . The fluorescent sensor has high sensitivity and good selectivity , which can be successfully applied in actual water samples with satisfactory recovery.
研究领域:
分析化学
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Separations
·
2024
·Vol. 11
·期 9
·274
·
IF 2.5
Wenjun Xu,Qianyi Wang,Jintao He,Fuzhen Liu,Xiang Yan,Yin Xu
The development of appropriate and effective periodate (PI) activation technology is currently a popular research area. This study presents a novel efficient photocatalytic activation approach of PI for pollutant degradation based on carbon nitride (g-C3N4) and visible light (Vis). The results show that the system can remove 92.3% of acid orange 7 (AO7) within 60 min under the g-C3N4/PI/Vis reaction system. The degradation rate constant (kobs) reached 4.08 × 10−2min−1, which is 4.21,5.16 times, and 51.3 times higher than that of the g-C3N4/Vis system (9.7 × 10−3min−1), PI/Vis system (7.9 × 10−3min−1) and the g-C3N4/PI system (7.96 × 10−4min−1), respectively. Clearly, the addition of PI significantly enhances the degradation efficiency of AO7 in the system. Additionally, under the same reaction conditions, the presence of PI showed excellent oxidation capacity in the photoactivation process compared with other common oxidants, such as peroxymonosulfate, peroxydisulfate, and H2O2. Moreover, the g-C3N4/PI/Vis system showed excellent removal of AO7 across a wide range of pH levels and in the presence of various anions. Electron paramagnetic resonance (EPR) and quenching experiments suggested that the superoxide anions (•O2−) and singlet oxygen (1O2) dominated in the oxidation of pollutants in the g-C3N4/PI/Vis system. In addition, the catalyst showed relative stability during cyclic testing, although a slight reduction in degradation efficiency was observed. In brief, the g-C3N4/PI/Vis system is highly efficient and environmentally friendly, with significant application potential in wastewater treatment.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）