REACTIVE & FUNCTIONAL POLYMERS
·
2025
·
IF 5.1
Ke Shang,Qingjing Niu,Xiaohui Li,Kongying Zhu,Lixia Ren,Xiaoyan Yuan
Ice formation can cause a serious of cryoinjuries to cells, and development of biocompatible cryoprotectants for ice control is of great importance. Herein, ice-nucleating glycopolymers are synthesized from the alternating copolymer, poly(methyl vinyl ether- alt -maleic anhydride) (PMVEA), by modification with small saccharides via one-step esterification. The prepared water-soluble glycopolymers can trigger ice nucleation at −14 to −12 °C, significantly higher than deionized water, linear poly(vinyl alcohol), and poly(ethylene glycol) (PEG). The structural differences in monosaccharide, disaccharide and trisaccharide-grafted glycopolymers have positive impacts on the chemically induced ice nucleation and the ice crystal morphology, but all of them have weak activities to inhibit ice recrystallization, similar like PEG. Analyses of differential scanning calorimetry and low field nuclear magnetic resonance suggest that the PMVEA-based glycopolymers, which have an alternating structure of hydrophobic methoxyl and hydrophilic carboxyl or saccharide residues, could have strong interactions with water molecules, thus initiating ice nucleation. Particularly, incorporation of trehalose-modified PMVEA in alginate hydrogel can enhance cryosurvival of Lactobacillus rhamnosus after cryopreservation at −20 °C in comparison with cryostorage at −80 °C. This work provides a feasible approach for preparation of ice-nucleating macromolecules for ice control during cryopreservation of cells.
研究领域:
生物材料学
·
低温生物学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POWER SOURCES
·
2022
·
IF 9.794
Chuan Wang,Hao Tang,Hongyu Zhu,Wu Tang,Shan Jia,Di Li,Yu Liu,Meichen Guo,Cong Fan
A novel organic polymer cathode namely poly(anthraquinone- alt -benzene) (PAQB, ∼190 mAh g −1 ) is intentionally designed and synthesized for sodium-ion batteries (SIBs). Full characterizations are carried out to define its polymer nature. Due to the strong π-π interaction of polymer main chains, the insoluble PAQB solid exhibits very efficient desolvation process against the solvated Na + ions in liquid electrolytes when compared to its insoluble dimer analogue (BAQB), leading to its highly impressive cycle stability and long material life. In half cells, PAQB can realize an average discharge capacity of 128 mAh g −1 during the ultra-long lifespan over 1 year. In the full cells with Na 3 Bi anode, the resulting PAQB II Na 3 Bi SIBs can realize the peak discharge capacity of 172 mAh g −1 cathode and stably hold 160 mAh g −1 cathode after 1000 cycles at 200 mA g −1 . To the best of our knowledge, PAQB is among the top cathodes currently reported for SIBs. And this work forwards a significant step for the application of organic electrodes in SIBs.
研究领域:
材料科学
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电化学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Chang Cheng,Xunchang Wang,Feng Wang
Two analogous positional polymers P16PySO and P27PySO have been synthesized via the copolymerization from dibenzothiophene-S,S-dioxide and pyrene building blocks. The effect of the linking pattern on the molecular packing, photophysical and photocatalytic properties of the two isomers was investigated. It was interestingly found that a minor change at the substitution position of pyrene unit was demonstrated to largely influence the photocatalytic properties of the two isomers. P16PySO exhibited an encouraging average hydrogen evolution rate (HER) of 619.5 μmol h −1 and the maximum HER of 774 μmol h −1 , much higher than that of 2,7-counterpart with a moderate rate of 282 μmol h −1 . The increased photocatalytic activity of P16PySO is mainly ascribed to its more ordered molecular packing, broader absorption region, better wettability , and higher photo-generated charge mobilities. Moreover, the optimum HER was increased from 774 to 1013 μmol h −1 when the amount of the photocatalyst P16PySO was increased from 50 to 100 mg, which is among the top solar-to‑hydrogen conversion efficiencies reported so far for the polymeric photocatalysts.
研究领域:
材料科学
·
化学
✓ 已验证
DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2021
·
IF 3.975
Zhiguo He,Xuejiao Han,Hui Xie,Zifeng Yan,Bing Guo,Youwei Yao
Near-infrared (NIR) conjugated polymer nanoparticles (CPNPs) possesses advantages for bioimaging because of their merits in low autofluorescence interference, good biocompatibility, large light extinction coefficient, improved photostability, and facile functionalization capability. Different from conventional post-polymerization methods for fabricating NIR CPNPs, like nanoprecipitation, emulsion and solvent evaporation/miniemulsion, and self-assembly, herein, an efficient one-pot strategy by in-situ miniemulsion polymerization is demonstrated to synthesize CPNPs for NIR fluorescence imaging of cancer cells. Via adjusting the donor-acceptor strength , the new CP, poly(fluorene- alt -6-(2-ethylhexyl)-[1,2,5]thiadiazole[3,4- f ]benzotriazole) ( PFTA ), show absorption and emission maximum at 648 nm and 730 nm, respectively, which is much more red-shifted than its counterpart, poly(fluorene- alt -benzo-2,1,3-thiadiazole) ( PFBT ). DFT calculation demonstrates that the repeating unit of PFTA has a smaller dihedral angel to 33.2° and much reduced energy gap to 2.46 eV, as compared to that of PFBT NPs. Importantly, through controlling surfactant concentrations from 40 g·L −1 to 2.5 g·L −1 during the miniemulsion polymerization, the particles size can be accordingly changed from even 88 to 210 nm. Furthermore, the particles show extinction coefficient of 2.82 × 10 4 M −1 ·cm −1 at 648 nm, photoluminescence quantum yields c.a. 2.4% and fluorescence lifetime c.a. 1.26 ns, respectively. Moreover, the PFTA NPs exhibit biocompatibility, good colloidal stability and bright fluorescence signals to clearly pinpoint breast cancer cells, with a trend that smaller NP size, higher cellular uptake. This work demonstrates the promise of miniemulsion polymerization as a facile method to fabricate NIR CPNPs for bioimaging.
研究领域:
生物学
·
医学
·
材料科学
✓ 已验证
DOI
高影响因子
CONSTRUCTION AND BUILDING MATERIALS
·
2023
·
IF 7.4
Bingzheng Jiang,Dong Chen,Li Wang,Wantai Yang
In this research, a novel method was developed to synthesize methoxy polyethylene glycol-grafted sulfonated poly(maleic anhydride- alt -styrene) (SPMS-g-mPEG) as cement superplasticizers. The method includes three main steps: 1) self-stabilized precipitation polymerization (2SP) of styrene and maleic anhydride for PMS microspheres; 2) gas-solid heterogeneous sulfonation reaction (GSR) of gaseous SO 3 with PMS microspheres; 3) intramolecular sulfonic acid-catalyzed esterification reaction of mPEG with sulfonated PMS (SPMS). GSR can achieve uniform sulfonation of PMS microspheres, while overcoming the inherent drawbacks of the traditional homogeneous solution sulfonation process. SPMS and SPMS-g-mPEG with different structural parameters and uniform structure were successfully prepared and their effects on the fluidity and fluidity retention of cement pastes were systematically compared. For the samples demonstrating the best dispersing ability, the hydration heat and setting time of cement pastes, adsorption kinetics and compressive strength of mortar samples were determined further. Our work provides an innovative and effective approach to superplasticizers with outstanding properties and its uniform structure facilitates the investigation on the relationship between structure and properties.
研究领域:
材料科学
·
化学工程
·
土木工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2023
·
IF 6.1
Tongwen Huang,Ke Zhang,Junqiao Wang,Kaihong He,Xingtao Zhou,Shaoping Nie
Acrylamide (ACR) generated in carbohydrate-rich foods during thermal processing has been demonstrated to exhibit hepatotoxicity. As one of the most consumed flavonoids with diet, quercetin (QCT) possesses the ability to protect against ACR-induced toxicity, albeit its mechanism is unclear. Herein, we discovered that QCT alleviated ACR-induced elevated levels of reactive oxygen species (ROS), AST, and ALT in mice. RNA-seq analysis revealed that QCT reversed the ferroptosis signaling pathway upregulated by ACR. Subsequently, experiments indicated that QCT inhibited ACR-induced ferroptosis through the reduction of oxidative stress. With autophagy inhibitor chloroquine, we further confirmed that QCT suppressed ACR-induced ferroptosis by inhibiting oxidative stress-driven autophagy. Additionally, QCT specifically reacted with autophagic cargo receptor NCOA4, blocked the degradation of iron storage protein FTH1, and eventually downregulated the intracellular iron levels and the consequent ferroptosis. Collectively, our results presented a unique approach to alleviate ACR-induced liver injury by targeting ferroptosis with QCT.
研究领域:
毒理学
·
药理学
·
分子生物学
·
细胞生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2026
·
IF 7.3
Bo Wang,Linjie Wang,Xinyu Chen,Zheng Tang,Jinjin Liu,Shuangquan Liu,Xi Chen,Hao Liang,Xiangheng Niu
Probing the activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) is of significance for clinical diagnosis of hepatic diseases and monitoring of therapeutic effects. Traditional detection methods often rely on a single signal driven by cascade catalysis of multiple natural enzymes, exposing weaknesses, including poor robustness and limited reliability. To overcome the deficiencies, here we design a novel nanoprobe (Na2V6O16/Cu-MOF) with both peroxidase-like catalytic and luminescent properties and establish a colorimetric/fluorescence bimodal method for the on-demand sensing of hepatic ALT and AST. In the bifunctional nanozyme, Na2V6O16 exhibits reposeful enzyme-like activity to trigger the oxidation chromogenic process of 3,3′,5,5′-tetramethylbenzidine (TMB) via H2O2-dependent free radical formation, and the 2-aminoterephthalic acid-coordinated Cu-MOF presents stable luminescence, which can be quenched by blue oxTMB from nanozyme catalysis via the inner filter effect. The presence of ALT or AST mediates the generation of H2O2, which consequently modulates the colorimetric turn-on and fluorescence readouts. With the enzyme–nanozyme cascade catalysis facilitated by Na2V6O16/Cu-MOF as well as its fluorescent feature, high-sensitivity bimodal detection of ALT and AST was obtained. Importantly, the established system offers robust catalytic performance, and the on-demand readouts enable mutual verification of different responses, both of which jointly improve the dependability of target analysis. Our work provides a reliable strategy for transaminase biomarker detection, contributing new insights into the design of multifunctional nanozymes and their applications in constructing advanced catalytic sensing platforms.
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产品关联
DOI
高影响因子
POLYMER INTERNATIONAL
·
2021
·Vol. 70
·期 11
·1612-1620
·
IF 2.99
Kuan Liu,Yuhan Wei,Jinyao Xu,Lingfei Qiu,Shaping Hu,Jiayi Wan,Juhua Feng
A novel conjugated polymer PFCZ-IM containing 2-(thiophen-2-yl)-1H-benzo[d]imidazole units was synthesized and characterized. The basic photophysical properties of the polymer and its fluorescence recognition behaviors toward metal ions and amino acids were investigated. In the study of the response of metal ions, PFCZ-IM had high sensitivity to Fe 3+ , Ag + and Cu 2+ , which significantly quenched the fluorescence of the polymer. The binding of the 2-(thiophen-2-yl)-1H-benzo[d]imidazole moiety to Cu 2+ was investigated by density functional theory calculation. Interestingly, [PFCZ-IM-Cu 2+ ] also exhibited outstanding characteristics of fluorescence ‘turn on’ in the presence of cysteine (Cys), as the interaction between Cu 2+ and Cys caused the polymer to dissociate from the complex. In particular, addition of 30 μmol L –1 of Cys can increase the Cu 2+ -quenching fluorescence of PFCZ-IM by 34.8 times with short response time, demonstrating that [PFCZ-IM-Cu 2+ ] has tremendous potential in the actual detection of Cys. This polymer is expected to be utilized for dual fluorescence detection of specific metal ions and Cys. © 2021 Society of Industrial Chemistry.
研究领域:
材料科学
·
分析化学
·
生物化学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Bingzheng Jiang,Jiaxin Li,Dong Chen,Li Wang,Wantai Yang
The development and application of high-efficiency coal-water slurry (CWS) dispersants can foster the clean utilization of natural coal. CWS with excellent flowability and stability requires good adsorption capacity of dispersant on pulverized coal surface, which is influenced substantially by the architecture and hydrophilicity of dispersants molecule. In this study, a series of neutralized sulfonated poly(styrene- alt -maleic anhydride) (NSPSM) with different molecular weight (M n ) and sulfonation degree (SD) were synthesized by self-stabilized precipitation polymerization (2SP), gas-solid heterogeneous sulfonation reaction (GSR) and neutralization reaction with NaOH. The performance of NSPSM for CWS, and their dispersion and stabilization mechanisms were investigated in detail. Under optimized conditions, maximum slurry concentration (MSC) and water separation ratio (WSR) of slurry with NSPSM could reach 66.5% and 2.0%, respectively, which are superior to commercial naphthalene sulfonate formaldehyde condensate (NSF) dispersant. The outstanding dispersibility of NSPSM was ascribed to its improved adsorption capacity due to increased charge density along polymer chain, which can prevent agglomeration among coal particles through electrostatic repulsion.
研究领域:
化学工程
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
POLYMER BULLETIN
·
2013
·Vol. 70
·期 6
·1795-1803
·
IF 1.332
Liu Jingcheng,Xiong Xiaomei,Liu Ren,Jiang Jinqiang,Liu Xiaoya
Novel branched alternating copolymers poly(styrene- alt -maleic anhydride) (BPSMA) were synthesized through free radical polymerization with styrene, maleic anhydride, and chain transfer monomer, 4-vinyl benzyl thiol. The successful synthesis of BPSMA was confirmed by a triple detection system including gel permeation chromatography, multiangle laser light scattering, and differential viscosity detectors, as well as thermal analysis (differential scanning calorimetry). This methodology proposes good prospects for scaling-up and thereby offers a wide range of branched alternating copolymers at low cost.
研究领域:
材料科学
·
高分子化学
✓ 已验证
DOI
高影响因子
JOURNAL OF PHYSICAL CHEMISTRY B
·
2015
·
IF 3.302
Dongdong Hu,Shaojun Sun,Peiqing Yuan,Ling Zhao,Tao Liu
Multiscale molecular modeling and dissolution behavior measurement were both used to evaluate the factors conclusive on the CO2-philicity of poly(vinyl acetate) (PVAc) homopolymer and poly(vinyl acetate-alt-maleate) copolymers. The ab initio calculated interaction energies of the candidate CO2-philic molecule models with CO2, including vinyl acetate dimer (VAc), dimethyl maleate (DMM), diethyl maleate (DEM), and dibutyl maleate (DBM), showed that VAc was the most CO2-philc segment. However, the cohesive energy density, solubility parameter, Flory–Huggins parameter, and radial distribution functions calculated by using the molecular dynamics simulations for the four polymer and polymer–CO2 systems indicated that poly(VAc-alt-DBM) had the most CO2-philicity. The corresponding polymers were synthesized by using free radical polymerization. The measurement of cloud point pressures of the four polymers in CO2 also demonstrated that poly(VAc-alt-DBM) had the most CO2-philicity. Although copolymerization of maleate, such as DEM or DBM, with PVAc reduced the polymer–CO2 interactions, the weakened polymer–polymer interaction increased the CO2-philicity of the copolymers. The polymer–polymer interaction had a significant influence on the CO2-philicity of the polymer. Reduction of the polymer–polymer interaction might be a promising strategy to prepare the high CO2-philic polymers on the premise that the strong polymer–CO2 interaction could be maintained.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2017
·Vol. 41
·期 23
·14539-14544
·
IF 3.269
Chao Li,Haochen Tan,Jingfang Pei,Chuan Wang,Cong Fan,Fangyi Huang,Bei Cao,Minghui Hao,Yuanxun Li,Zhihong Wang,Jingze Li
A novel polymer (PTPBQ) with alternating terephthalate (TP) and benzoquinone (BQ) moieties is synthesized for the first time as an organic cathode for Li-ion batteries. Both TP and BQ moieties probably could remain electrochemically active and thus may make PTPBQ realize a maximum 4-electron redox behaviour and a theoretical specific capacity of up to ∼390 mAh g−1. In its practical application, Li-ion half cells based on PTPBQ can realize discharge capacities of ∼110 mAh g−1 on average for 400 cycles (40 mA g−1, 0.1C), and ∼180 mAh g−1 on average for 200 cycles (80 mA g−1, 0.2C) when the carbon additive is augmented to 40 wt%.
研究领域:
材料科学
·
储能
·
聚合物化学
·
电化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）