JOURNAL OF MATERIALS CHEMISTRY
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2012
·Vol. 22
·期 41
·21979-21986
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IF 5.968
Meina Wang,Xiangyou Liu,Chuanbao Cao,Long Wang
Monodisperse CuInS2–ZnS nanocrystals were synthesized in organic solvents and effectively transferred to aqueous phase with the aid of trimethyl(tetradecyl)ammonium bromide (TTAB). TTAB-stabilized CuInS2–ZnS (CIS–ZnS–TTAB) nanocomposites exhibited good aqueous stability and preserved the high luminescence of the nanocrystals after phase transfer. More intriguingly, without any further modification, CIS–ZnS–TTAB showed a striking nuclear homing property, preferentially accumulating in the nuclei of living cells. This novel probe CIS–ZnS–TTAB may have applications in nuclear selective imaging and as a multifunctional drug carrier for nuclear targeted drug delivery. Our work provides a simple but effective way for hydrophobic nanomaterials to achieve both phase transfer and nuclear selectivity simultaneously.
研究领域:
材料科学
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生物医学工程
·
纳米技术
✓ 已验证
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2021
·
IF 4.464
Zhipeng Li,Shuo Wu,Guizheng Zou
Discriminating the electrochemiluminescence (ECL) of differed luminophores is crucial for ECL multiplexing. However, because of the limited potential window for ECL assay and the overlapped triggering-potential-range between different luminophores, the potential-resolved ECL multiplexing with good resolutions ( R s ) is still a great challenge. Herein, a single anodic ECL from two luminophores in the aqueous solution was discriminated completely (baseline separation, R s ≥ 1.5) in a potential-resolved way with the water-soluble CuInS 2 @ZnS ( [email protected] ) nanocrystals (NCs) and [Ru(bpy) 2 (dcbpy)] 2+ as luminophores and N 2 H 4 as the co-reactant. N 2 H 4 could be electrochemically oxidized to reducing radicals and then reacted with the electrochemically oxidized [email protected] NCs and [Ru(bpy) 2 (dcbpy)] 2+ in sequence to produce co-reactant ECL. The potential-resolved ECL of [email protected] NCs/N 2 H 4 and [Ru(bpy) 2 (dcbpy)] 2+ /N 2 H 4 could be well defined and distinguished from each other upon potential scanning ( R s = 2.60) and utilized for simultaneously determining human prostate specific antigen and carcinoma antigen 125 at the pathological cut-off concentration ( R s = 1.56).
研究领域:
分析化学
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生物化学
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材料科学
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生物医学工程
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DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2022
·
IF 4.831
Xiaoping Chen,Jianwei Lin,Yafeng Zhuang,Siqi Huang,Jinghua Chen,Zhizhong Han
A new ratiometric fluorescence sensor is prepared for selective detection of chlorotetracycline (CTC) through dual-mode fluorescence method. The sensor is composed of carbon dots (CDs) with blue emission and carboxyl-modified CuInS 2 /ZnS quantum dots (QDs) with dark-red emission. Usually QDs are used as fluorescent probes or signal sources, but it is interesting in this strategy that CuInS 2 /ZnS QDs innovatively work as quenching agent to reduce the fluorescence of CDs, mainly due to the fluorescence resonance energy transfer (FRET). After the addition of CTC, the interaction between CDs and CuInS 2 /ZnS QDs is restrained, resulting in the fluorescence recovery of CDs, whilst the QDs’ fluorescence remains unaffected. In this work, CTC is detected in the range of 0–50 μM by conventional fluorescence and synchronous fluorescence methods under an excitation wavelength of 360 nm or Δλ = 90 nm, and the detection limits of the two methods are 0.46 μM and 0.36 μM, respectively. The designed sensor displays good selectivity compared with other tetracycline drugs with similar structure to CTC, different ions and various natural - amino acids. And the sensor can also be applied to determine CTC in tap water and milk.
研究领域:
分析化学
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纳米技术
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环境科学
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食品科学
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DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2020
·
IF 4.65
Bing Deng,Yanqing Zhu,Jingling Li,Xia Chen,Kun He,Juan Yang,Kaili Qin,Zhuoneng Bi,Xiudi Xiao,Shuaijun Chen,Xueqing Xu,Gang Xu
The Publisher regrets that this article is an accidental duplication of an article that has already been published in , http://dx.doi.org/10.1016/j.jallcom.2020.155439 . The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal
研究领域:
材料科学
·
光学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2019
·
IF 6.361
Liwang Liu,Hong Li,Zirui Liu,Ya-Hong Xie
Colloidal quantum dots (QDs) have attracted a great amount of attention for their appealing optoelectronic properties. In this work, the CuInS 2 (CIS)/ZnS core/shell QDs based on 4.3 nm cores with various layers of ZnS shell (0 to 10) were synthesized. With the sequential growth of a ZnS shell over a CIS core, the band alignment of core/shell QDs converts from a type I to quasi-type II structure. This conversion prolongs the carrier lifetime and affects the electron transfer rate ( K et ) and electron transfer efficiency ( η ET ). A comparative study indicates that the photovoltaic performance of CIS based QDSCs can be markedly improved by optimizing the layers of ZnS shell. The highest photo conversion efficiency (PCE) of 2.07% is obtained at optimum ZnS thickness of about 1.55 nm. These results show tuning the thickness of shell to change the band alignment is an effective strategy to manipulate the carriers transportation behaviors and thus affect the PCE of CIS-based optoelectronic devices.
研究领域:
材料科学
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光电子学
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产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2014
·Vol. 5
·期 11
·8404-8414
·
IF 3.708
Yongbo Yang,Jinrui Wang,Xiaoda Li,Li Lin,Xiuli Yue
This paper reported the development of a multifunctional contrast agent for near infrared (NIR) fluorescent/ultrasonic bimodal imaging and gene delivery. CuInS2–ZnS alloyed quantum dots (ZCIS QDs) were coated with polyethyleneimine (PEI) to complex plasmid DNA (pDNA), followed by adsorption onto the surface of microbubbles (MBs) generated from the surfactant mixture of Span 60 and Tween 80. It was found that the obtained composite agent of MBs@QDs@PEI/pDNA had excellent capability to enhance both ultrasound and fluorescence imaging. In addition, an in vitro cell experiment showed that pDNA could be released from MBs@QDs@PEI/pDNA and internalized by target HeLa cells to realize a relatively high transfection efficiency by ultrasound-targeted microbubble destruction. Furthermore, the cytotoxicity, immune toxicity and histological evaluation showed that MBs@QDs@PEI/pDNA had a good biocompatibility for medical application. Therefore, such a multifunction agent could operate as a promising platform for targeting gene delivery under the guidance of NIR fluorescent/ultrasonic bimodal imaging.
研究领域:
医学影像
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基因治疗
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纳米技术
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生物医学工程
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DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2022
·
IF 8.008
Xuwen Gao,Xiancheng Liu,Ying Zeng,Qingqing Zhang,Bin Zhang,Guizheng Zou
The investigation on electrochemiluminescence (ECL) multiplexing bioassays mainly focuses on simultaneously detecting either proteins or nucleic acids. To overcome the limitation of a short waveband for spectrum-resolved ECL multiplexing bioassays, herein, a highly monochromatic (FWHM <40 nm) and bandgap-engineered ECL luminophore, that is, mercaptopropionic acid-capped and Zn2+-mediated aggregation-induced emission (AIE) assembly of Au nanocrystals (NCs) (Zn2+-AIE-AuNCs), of strong emission and the maximum emission wavelength at 485 nm is developed. The highly monochromatic and bandgap-engineered ECL (485 nm) of Zn2+-AIE-AuNCs can multiplex with the single-waveband and surface-defect-involved ECL (775 nm) of dual-stabilizer-capped CuInS2@ZnS NCs (CIS@ZnS-NCs), enabling a spectrum-resolved ECL multiplexing strategy with different NCs luminophores of a similar particle size as tags. This ECL multiplexing strategy can be utilized to simultaneously detect antigen and DNA probe together without any additional signal amplification procedure and obvious spectroscopic cross-talk, in which the highly monochromatic ECL from Zn2+-AIE-AuNCs is utilized to dynamically determine human carcinoembryonic antigen from 1 pg/mL to 50 ng/mL with a limit of detection (LOD) of 0.3 pg/mL, while the single-waveband ECL from CIS@ZnS-NCs is employed to linearly detect wild-type p53 from 1 pM to 50 nM with a LOD of 0.5 pM. The ECL immunoassay of the proposed strategy is free from the interference of the synchronously conducted DNA probe assay and vice versa, which would open an avenue to couple the immunoassay and DNA probe assay together for clinical colon and breast cancer identification.
研究领域:
分析化学
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生物医学工程
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纳米技术
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临床诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）