C-Journal of Carbon Research
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2024
·Vol. 10
·期 3
·62
·
IF 3.9
Xuexin Yuan,Qiqi Zhou,Yu Chen,Hai-Jian Yang,Qingqing Jiang,Juncheng Hu,Cun-Yue Guo
In the present work, inexpensive and commercially available diethyltriamine pentaacetic acid (DTPA) was used as an initiator to catalyze the N-formylation reaction of CO2with amines via the construction of C-N bonds in the presence of xanthone as the photosensitizer and PhSiH3as the reducing agent. After a systematic study of various factors, the optimal conditions for the photocatalytic reaction were obtained: 2.5 mmol of amine, 2.5 mmol of PhSiH3, 10 mol% of DTPA, 20 mol% of xanthone, 1 mL of dimethylsulfoxide (DMSO), atmospheric pressure, and 35 W UV lamp irradiation for 48 h. Under the optimal conditions, the catalyst system afforded high performance for the N-formylation of amines (primary and secondary amines) and CO2, and the yields of the N-formylated products of dialkylamines were above 70%. Further studies exhibit that the catalytic system has a wide scope of substrate applications. For various alicyclic secondary amines, heterocyclic secondary amines, aliphatic primary amines, and aromatic primary amines, the corresponding N-formylation products can be obtained efficiently. In addition, the catalyst can be recycled by simple precipitation and filtration. After five cycles of recycling, there was no significant change in the catalytic and structural properties of DTPA. Finally, a possible reaction mechanism is proposed.
研究领域:
化学
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环境科学
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材料科学
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DOI
高影响因子
CHEMOSPHERE
·
2019
·
IF 5.108
Chenglong Yu,Erping Bi
Use of reclaimed water for irrigation is a main way for pharmaceutical compounds such as diclofenac getting into the soil environment. However, the role of minerals, especially iron oxides , in the diclofenac adsorption to soils with low soil organic matter (SOM) is still in the lack of evaluation. In this study, adsorption of diclofenac onto six minerals (five nature minerals-hematite, goethite , magnetite, kaolinite and aluminium oxide and one engineered mineral-activated aluminia) and five reference soils was investigated by column chromatography. Adsorption of diclofenac onto minerals and soils was totally reversible and interactions such as H-bonding were the primary mechanisms. Adsorption affinity of iron oxides was much higher than that of nature silicon and aluminum oxides. Diclofenac tended to be adsorbed by mineral surface -OH groups with high thermodynamic stability, which were dehydroxylated at high temperature. Compared with the SOM-dominated sorption of naphthalene , adsorption of diclofenac onto soils was controlled by bonding with surface -OH groups of iron oxides. Adsorption coefficients of diclofenac onto soils can be well predicted by contents of extracted Fe by diethylenetriamine pentaacetic acid (DTPA) instead of total iron oxides contents, suggesting that the bonding was adsorption site-dependent. These findings highlighted the importance of iron oxides in the adsorption of diclofenac (an anionic pharmaceutical compound) in soils with relatively low SOM (e.g., 1.03-3.45%). It also indicated that contents of effective surface -OH groups and DTPA-Fe were the promising parameters to develop the predictive models for diclofenac adsorption onto minerals and soils, respectively.
研究领域:
环境科学
·
土壤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2014
·
IF 6.007
Qi Huang,Menghua Cao,Zhihui Ai,Lizhi Zhang
In this study, an environmentally benign polyaminocarboxylic ligand diethylenetriamine pentacetate (DTPA) was first used to promote the aerobic 4-chlorophenol (4-CP) degradation with Fe@Fe 2 O 3 core–shell nanowires, and then compared with the most used counterpart ethylenediamine tetraacetate (EDTA) of poor biodegradability. Although the 4-CP removal rate in the Fe@Fe 2 O 3 /DTPA/Air system was slower owing to the preferential degradation of DTPA, the total organic carbon removal rate in the Fe@Fe 2 O 3 /DTPA/4-CP/Air system was much faster than that in the Fe@Fe 2 O 3 /EDTA/4-CP/Air system. We interestingly found that hydroxyl radicals could more easily react with DTPA to produce DTPA radicals than with EDTA to produce EDTA radicals. Ligands (DTPA or EDTA) could significantly accelerate the hydroxyl radicals production with Fe@Fe 2 O 3 , while more hydroxyl radicals were generated in the Fe@Fe 2 O 3 /DTPA/Air system. We also employed gas chromatography-mass spectrometry and ion chromatography to detect organic intermediates and chloride ions to probe the 4-chlorophenol degradation pathways, and found its degradation pathways were dependent on the reactive oxygen species generated in the different systems. This study can clarify the roles of polyaminocarboxylic ligands on the molecular oxygen activation with nanoscale zero-valent iron, and also provide a green chlorophenols removal method.
研究领域:
环境科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Miao Jiang,Kun Wang,Gen Li,Qingliang Zhao,Weiye Wang,Junqiu Jiang,Yipeng Wang,Luzi Yuan
Co-contamination of As, Sb, and Pb in soil has aroused public concern due to their wide application in industries. However, the efficient stabilization materials with simultaneous cations and anions stabilization capacities are still lacking and remain a challenge. Herein, a new type of montmorillonite modified by amorphous ferrihydrite ( [email protected] ) was synthesized and the immobilization performance of [email protected] for As, Sb, and Pb in soil was investigated comprehensively, mainly by TCLP, SBET, and DTPA extraction. The stabilization efficiency assessed by TCLP reached 86.28 % for Sb and 94.60 % for Pb after 56 days, and the As could not be detected in the leachate after 10 days. For As, Sb and Pb, the SBET method achieved a reduction of 87.34 %, 54.59 % and 17.59 % respectively. The DTPA extractable content of the metal(loid)s also declined significantly, especially for As. By applying [email protected] , the soil properties as well as the bacterial richness and diversity in the soil were obviously improved. The [email protected] adsorption data are well fitted to the Langmuir model and the pseudo-second-order model. The principal stabilization mechanisms were ascribed to inner-sphere complexation, surface precipitation and co-precipitation, and structural incorporation into [email protected] This is the first study to exhibit the feasibility of [email protected] as an effective and environmentally friendly stabilizer for remediation of As/Sb/Pb co-contaminated soils.
研究领域:
环境科学
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土壤修复
·
地球化学
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DOI
高影响因子
Regenerative Biomaterials
·
2021
·Vol. 8
·期 6
·
IF 6.353
Yang Li,Fu Shengxiang,Cai Zhongyuan,Liu Li,Xia Chunchao,Gong Qiyong,Song Bin,Ai Hua
The T1−T2 dual-mode probes for magnetic resonance imaging (MRI) can non-invasively acquire comprehensive information of different tissues or generate self-complementary information of the same tissue at the same time, making MRI a more flexible imaging modality for complicated applications. In this work, three Gadolinium-diethylene-triaminepentaaceticacid (Gd-DTPA) complex conjugated superparamagnetic iron oxide (SPIO) nanoparticles with different Gd/Fe molar ratio (0.94, 1.28 and 1.67) were prepared as T1–T2 dual-mode MRI probes, named as SPIO@PEG-GdDTPA0.94, SPIO@PEG-GdDTPA1.28 and SPIO@PEG-GdDTPA1.67, respectively. All SPIO@PEG-GdDTPA nanocomposites with 8 nm spherical SPIO nanocrystals showed good Gd3+ chelate stability. SPIO@PEG-GdDTPA0.94 nanocomposites with lowest Gd/Fe molar ratio show no cytotoxicity to Raw 264.7 cells as compared to SPIO@PEG-GdDTPA1.28 and SPIO@PEG-GdDTPA1.67. SPIO@PEG-GdDTPA0.94 nanocomposites with r1 (8.4 mM−1s−1), r2 (83.2 mM−1s−1) and relatively ideal r2/r1 ratio (9.9) were selected for T1–T2 dual-mode MRI of blood vessels and liver tissue in vivo. Good contrast images were obtained for both cardiovascular system and liver in animal studies under a clinical 3 T scanner. Importantly, one can get high-quality contrast-enhanced blood vessel images within the first 2 h after contrast agent administration and acquire liver tissue anatomy information up to 24 h. Overall, the strategy of one shot of the dual mode MRI agent could bring numerous benefits not only for patients but also to the radiologists and clinicians, e.g. saving time, lowering side effects and collecting data of different organs sequentially.
研究领域:
医学影像学
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纳米医学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
EUROPEAN POLYMER JOURNAL
·
2018
·
IF 3.741
Li Song,Bao Zhang,E Jin,Chunsheng Xiao,Gao Li,Xuesi Chen
Herein, a novel kind of reduction and thermal dual-responsive polymer was synthesized by direct condensation polymerization of poly(ethylene glycol) (PEG) and 3,3′-dithiodipropanoic acid (DTPA). The resulting PEG-DTPA copolymers were soluble in water at room temperature and exhibited reversible thermal-responsive behaviors. The cloud point temperatures of PEG-DTPA copolymers were highly tunable dependent on the polymer concentration and the length of PEG segment. Additionally, the PEG-DTPA copolymers exhibited reduction-responsive behavior due to the presence of disulfide linkage groups in the backbone. This reduction-responsive property allowed the PEG-DTPA copolymers to be used in a drug delivery system. Thus, a triblock copolymer composed of mPEG2k and PEG400-DTPA copolymer was synthesized. The obtained copolymers could self-assemble into spherical micelles and exhibited thermal and reduction dual-responsive structure-variations in aqueous media. Furthermore, the hydrophobic Nile Red was effectively encapsulated into the micelles. The micelles maintained excellent reduction-responsive properties and can release drugs by reduction triggering. These results suggested that the PEG-DTPA copolymer may be promising for use as reduction and thermal dual-responsive drug carriers in cancer therapy.
研究领域:
高分子化学
·
药剂学
·
生物医学工程
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Lu Zhao,Li Ma,Xuetao Jia,Xiaoxue Wang,Wenjing Hou,Gang Shu,Bing Han,Dianxun Fu,Dong Li,Shao-Kai Sun,Jinbin Pan
Contrast-enhanced computed tomography perfusion (CTP) imaging is a critical clinical tool for evaluating cerebral blood flow after acute ischemic stroke (AIS), enabling accurate diagnosis and treatment planning. However, conventional iodine-based contrast agents may lead to allergic reactions and are contraindicated in patients with thyroid disorders. This study introduces Bi-DTPA dimeglumine, a renal-clearable and iodine-free bismuth chelate, for AIS perfusion assessment via CTP imaging. Bi-DTPA dimeglumine is synthesized through a simple and scalable process with nearly 100% yield (laboratory synthesis >100 g) and demonstrates excellent biocompatibility and efficient renal clearance. In a middle cerebral artery occlusion (MCAO) rat model, Bi-DTPA dimeglumine-enhanced CTP imaging accurately visualized vascular perfusion deficits, showing reduced cerebral blood volume (CBV) and cerebral blood flow (CBF), alongside prolonged time-to-maximum (Tmax) and mean transit time (MTT). Compared to iohexol, Bi-DTPA dimeglumine provided superior vascular contrast in computed tomography angiography (CTA), with contrast-to-noise ratio (CNR) improvements of 129.8 and 93.5% in normal and MCAO rats, respectively. Notably, CTP imaging revealed distinct reperfusion dynamics in ischemic regions postrecanalization. This iodine-free imaging agent marks a significant advancement in precise AIS diagnosis and post-treatment evaluation, addressing key limitations of existing contrast agents while enhancing diagnostic accuracy and safety.
研究领域:
医学影像学
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神经科学
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药理学
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Jie Zhang,Xibin Zhou,Jun Wang,Dawei Fang
In this work, a novel Eu 3+ -DTPA-bis(AMC) complex with red luminescence was designed and synthesized for sequential detection of Cu 2+ and biothiols (Cys/Hcy/GSH) based on the displacement strategy with the good selectivity, high sensitivity, and large Stokes shift (288 nm). The possible detection mechanism was verified by UV–vis, the high-resolution mass spectrometry, and the fluorescence decay curve. The experimental parameters, including the solution pH, the incubation time, the concentration ratio of Eu 3+ -DTPA-bis(AMC) to Cu 2+ and biothiols concentration, were optimized. Under the optimal conditions, it shows a good linear relationship between the concentration (0–10 μM) of Cu 2+ and the fluorescence intensity of Eu 3+ -DTPA-bis(AMC), with a low detection limit of 0.065 μM. The linear range and the limit of detection of the Eu 3+ -DTPA-bis(AMC)/Cu 2+ system for Cys/Hcy/GSH were 2.5–22.5/5–45/5–50 μM and 0.11/0.07/0.05 μM, respectively. Surprisingly, the high or low concentration of Eu 3+ -DTPA-bis(AMC)/Cu 2+ can significantly affect the selectivity of the sensing system to biothiols (Cys/GSH/Hcy). When the concentration of the Eu 3+ -DTPA-bis(AMC)/Cu 2+ system is 10.0 μΜ, it could recognize biothiols (Cys/GSH/Hcy) from other substances, but when the concentration is as low as 3.3 μM, it could further specifically distinguished Cys from Hcy/GSH. Owing to the high anti-interference characteristics, accuracy and specificity, the sensing system was well applied to the cascade detection of Cu 2+ in actual environmental samples and Cys in biological and food samples, including FBS, urine, milk, beverage, fresh juice with the satisfactory recoveries from 96.20 to 106.80 %.
研究领域:
分析化学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2026
·
IF 3.9
Ai Xin,Zhang Xiao-Fei,Xu Yu-Lin,Li Ya-Fei,Zuo Xiao-Hua,Zhang Xiao-Lei,Wei Jie,Xie Quan-Wei
Iron-chromium redox flow batteries (ICRFBs) have emerged as a promising candidate for large-scale energy storage due to their cost-effectiveness, long cycle life, power-energy decoupling, and inherent safety. However, conventional ICRFBs using acidic FeCl₂ + CrCl₃ + HCl electrolytes face critical challenges, including severe material corrosion, active species cross-contamination, and parasitic hydrogen evolution reactions. To address these issues, we propose a neutral chelated Fe/Cr electrolyte system utilizing the identical ligand, 1,3-diaminopropanetetraacetic acid (DTPA), for both half-cells. This symmetric ligand design effectively suppresses metal ion crossover while enhancing redox kinetics, as confirmed by Fourier transform infrared (FTIR) and ultraviolet–visible (UV–vis) spectroscopy. The DTPA-complexed electrolytes exhibit high solubility (up to 1.0 mol/L) and environmental benignity, eliminating the need for corrosive acids. The resulting ICRFB demonstrates outstanding performance: a discharge energy density of 12.1 Wh/L, an average capacity decay rate of 0.13% per cycle over 300 cycles, and a coulombic efficiency approaching 100% at 50 mA/cm 2 , with a round-trip energy efficiency of 60%. These metrics are comparable to those of traditional acidic systems but with significantly reduced material degradation and operational risks. Our work validates the chelation strategy as a viable pathway to develop low-cost, long-lifetime ICRFBs, accelerating their practical deployment in grid-scale energy storage applications. Graphical
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Xiaojie Zhang,Kangrui Ma,Hong Peng,Yuefa Gong,Yanjun Huang
Simultaneous removal of chromium(VI) oxyanions and heavy metal cations from contaminated water body is of great significance. In this work, a novel and bifunctional sorbent, imidazolium functionalized polysulfone/DTPA-chitosan composite bead (IMPSF/DACS) was successfully constructed by phase inversion method and applied for co-removal of Cr(VI) and Cu(II) from aqueous solutions. The maximum adsorption capacities for Cr(VI) and Cu(II) on IMPSF/DACS in single system at pH 5 were 56.72 and 43.05 mg g −1 , respectively. In binary system, the removal of Cr(VI) could be further enhanced by the presence of Cu(II) due to the electrostatic shielding effect, while Cu(II) sorption was not significantly affected by the coexistence of Cr(VI). Moreover, IMPSF/DACS could simultaneously reduce low concentrations of Cu(II) and Cr(VI) in simulated contaminated lake water below the limit, while also showing good reusability in co-removal of Cr(VI) and Cu(II). The order of inhibitory effect of competing anions on Cr(VI) removal was as follows: H 2 PO 4 − < Cl − < NO 3 − < SO 4 2− , while the competing hardness cations had a little effects on the adsorption of Cu(II), implying that the Cr(VI) removal was mainly depended on the electrostatic attraction between Cr(VI) and imidazolium ions modified on IMPSF/DACS, and Cu(II) uptake was associated with chelation of DACS encapsulated in IMPSF/DACS beads. These assumptions were confirmed by XPS, FTIR and EDS-mapping techniques.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2023
·Vol. 332
·期 4
·1237-1244
·
IF 1.6
Xi Wenke,Zhang Ge,Xue Jingquan,Li Juan,Liu Yu,Wang Jianjun,Yang Wenjiang
Multimodal imaging has become a trend in the development of molecular imaging. For SPECT/MRI dual-modality imaging, we developed a SPECT/MRI dual-modality probe based on superparamagnetic iron oxide nanoparticles. RGDyk peptide and DTPA chelator were used to realize the functionalization of nanoparticles. Both SPECT imaging and T2-weighted MR imaging in vivo on 4T1 tumor-bearing mice showed targeting of the probe, demonstrating the potential of the SPECT/MRI dual-modality probe as a tool for tumor evaluation and diagnosis.
研究领域:
医学影像学
·
分子生物学
·
纳米医学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL PHYSICS LETTERS
·
2010
·
IF 2.291
Chengling Han,Tingting Chen,Lily Zu
A terbium chelate formed with diethylenetriaminepentaacetic acid and p -aminosalicylic acid (Tb–DTPA–pAS) was labeled on a 23-mer DNA strand and used as donor in the fluorescence resonance energy transfer (FRET) study of DNA hybridization. The change in donor fluorescence lifetime with and without DNA-bind acceptor carboxytetramethylrhodamine (TAMRA) showed high energy transfer efficiency (87%). The distance between the two ends of the 23-mer double-stranded DNA was estimated. This study provides a possibility of using the Tb-chelate as a probe in the studies of the geometry-dependent interaction between DNA strands or proteins.
研究领域:
化学
·
分子生物学
·
生物物理学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）