JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2021
·Vol. 33
·期 31
·23880-23887
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IF 2.478
Ding Yanli,Zhang Xiaodan,Zhao Ying
The use of upconversion (UC) materials is an effective strategy for harvesting the near-infrared (NIR) solar photons in perovskite solar cells. Hexagonal β-NaLuF 4 :Yb,Er submicron prisms were synthesized by a facile solvothermal method. Gd 3+ doping is used to enhance the UC emission intensity. We investigated how the concentration of Gd 3+ ions affected the morphological evolution, microstructure, and luminescence performance of NaLuF 4 :Yb,Er and explored the mechanism for improving luminescence at 980 nm excitation. By incorporating the optimized NaLuF 4 :Yb,Er,Gd into the perovskite solar cells’ (PSCs) hole transport layer, the short-circuit density ( J sc ) of UC-PSCs can be enhanced from 19.31 to 21.77 mA cm −2 .
研究领域:
材料科学
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光学
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能源科学
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产品关联
DOI
高影响因子
JOURNAL OF ETHNOPHARMACOLOGY
·
2015
·
IF 2.998
Hui-Hui Xiao,Quan-Gui Gao,Ming-Xian Ho,Yan Zhang,Ka-Chun Wong,Yi Dai,Xin-Sheng Yao,Man-Sau Wong
Ethnopharmacological relevance Sambucus williamsii Hance (SWH), which belongs to the Caprifoliaceae family distributed in various regions of China, Korea and Japan, has been used as a folk medicine for treatment of bone and joint diseases in China for thousands of years. In previous studies, SWH was shown to possess anti-osteoporosis, healing fracture, anti-inflammatory and analgesic activities. Our previous studies showed that SWH extract effectively suppressed ovariectomy-induced increase in bone turnover and improved bone mineral density and bone biomechanical strength in rats as well as in mice. An 8- O -4′ norlignan, (7 R ,8 S )-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-1,3-propanediol (PPD) was previously isolated and identified as the bioactive ingredient in SWH. The present study aimed to characterize the bone protective effects as well as its mechanism of actions in osteoblasts. Materials and methods Bone protective actions of PPD on different cells were determined by proliferation assay, alkaline phosphatase (ALP) activity assay, calcium deposition as well as real-time reverse transcriptase-polymerase chain reaction (RT-PCR). In addition, estrogen receptor (ER) antagonist ICI182,780 and mitogen-activated protein kinase kinase (MEK) inhibitor U0126 blocking assays, competitive ER radioligand binding assay, ERE-dependent luciferase reporter assay and immunoblotting were used to determine if PPD activated ER and if the effects of PPD on osteoblastic functions were ER dependent. Results PPD exerted anabolic effects in osteoblasts and its effects were abolished by co-incubation with ICI182,780 or U0126. PPD induced mRNA expressions of Runx2, ALP, osteocalcin, and increased the ratio of osteoprotegerin/receptor activator of nuclear factor κB (OPG/RANKL). PPD failed to bind to either ERα or ERβ and did not activate ERE-luciferase activity via ER. PPD induced the phosphorylation of extracellular regulated kinases (ERK) and its effect was completely abolished by U0126. It also induced the phosphorylation of ERα at serine 118. Conclusion These data show that PPD is a bioactive compound in SWH that exerts oestrogen-like actions in osteoblast-like cells via ligand-independent, estrogen response element (ERE)-independent and mitogen-activated protein (MAP) Kinase-mediated rapid nongenomic ER signaling pathway.
研究领域:
民族药理学
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分子生物学
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骨代谢研究
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2020
·Vol. 20
·期 3
·1866-1872
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IF 1.134
Li Na,Tan Haihu,Xie Shaowen,Liu Simin,Tong Chao,Ouyang Min,Xu Lijian
Upconversion nanocrystals with uniform size and hydrophilic surface have potential applications in biological medical engineering. In this study, hydrophilic NaYF4:Yb, Er nanospheres were synthesized via hexadecylpyridinium chloride (CPC) mediated hydrothermal process. The
synthesized NaYF4:Yb, Er upconversion nanospheres (UCNSs) were characterized by various characterization methods. Results showed that the synthesized UCNSs exhibited a uniform sphere-like structure with average diameter of ~250 nm. The surface of UCNSs was captured by CPC molecule
indicating hydrophilic properties of UCNSs. The spherical UCNSs composed of mixed phase (α+β) NaYF4 nanocrystals. This is the novel study for synthesis of NaYF4:Ln3+ crystal employing CPC as ligand. Moreover, the effect of CPC concentration on
synthesis of UCNSs was investigated by comparatively studying morphology, crystal phase and luminescent properties of desired sample prepared under different experimental conditions. It was found that high concentrations of CPC ligands were more favorable for forming NaYF4 crystal
nanospheres with morphology that is more regular, have smoother surface, with higher crystallinity and better upconversion fluorescent properties. The possible growing mechanism was proposed and growing of NaYF4:Yb, Er nanospheres followed the classical Ostwald ripening process.
研究领域:
材料科学
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生物医学工程
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纳米技术
✓ 已验证
DOI
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
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2014
·Vol. 16
·期 37
·20009-20012
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IF 4.198
Bin Dong,Rui N. Hua,Bao S. Cao,Zhi P. Li,Yang Y. He,Zhen Y. Zhang,Otto S. Wolfbeis
The size-dependent temperature sensitivity is observed on the upconversion luminescence of NaYF4:Er,Yb microspheres with sizes between 0.7 and 2 μm that are prepared by a poly(acrylic acid)-assisted hydrothermal process. It is found that the fluorescence intensity ratio (FIR) of their green upconversion emissions (with peaks at 521 and 539 nm) is strongly size-dependent at temperatures between 223 and 403 K. As the size of the spheres increases from 0.7 to 1.6 μm, the maximum sensitivity decreases from 36.8 × 10−4 to 24.7 × 10−4 K−1. This effect is mainly attributed to the larger specific surface area of the smaller spheres where a relatively large number of Er(III) ions are located at the surface. This results in an increase in the efficiency of the 4S3/2 → 2H11/2 population process of the Er(III) ions due to stronger electron–phonon interactions with increasing T. Heating of the spheres by NIR light is also supposed to cause enhanced electron–phonon interactions in such particles.
研究领域:
材料科学
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光学
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纳米技术
✓ 已验证
DOI
高影响因子
ACS Applied Nano Materials
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2023
·
IF 5.9
Ru-Kun Ding,Xiao-Song Zhang,Long Liu,Xiao-Kai Gong,Zhao-Wei Zhang,Qian Li,Liu Pei,Lan Li,Jian-Ping Xu
Lead halide perovskites have garnered widespread attention because of their excellent photoelectric and photonic properties. However, their material fabrications and optoelectronic applications are hindered by low stability. Nanoriveted structure perovskites with high stability and long afterglow dual-wavelength emission are synthesized using a shared ion strategy of perovskites and phosphors. The CsPbBr3/CsCaAl2O4:Nd,Er nanoriveted structure perovskites exhibit dual-wavelength emission of blue and green during photoexcitation, as well as a prolonged afterglow. The fabricated flexible electroluminescent devices have spectrally tunable and dual-wavelength emissions even at 60° bending. Because the CsPbBr3 quantum dots (QDs) capture the photon emitted from Er element, the electroluminescent devices retain observable dual-wavelength emissions and high synchronization in their afterglow, which decays after the removal of power. The CsPbBr3/CsCaAl2O4:Nd,Er nanoriveted structure perovskites can also be used as the light-emitting downshift layers to improve the performance of photovoltaic modules in photovoltaic devices. At cryogenic temperatures, the temperature-dependent photoluminescence spectra test reveals the energy transfer between CsPbBr3 QDs and CsCaAl2O4:Nd,Er (contradicts the energy transfer in the afterglow state). These discoveries overcome the limitations of conventional afterglow phosphors, provide new applications for long afterglow materials, and introduce an innovative approach to energy conservation.
研究领域:
材料科学
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光电技术
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纳米技术
✓ 已验证
DOI
高影响因子
OPTICAL MATERIALS
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2025
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IF 4.2
Haoran Zhang,Tianxi Feng,Song Ye,Deping Wang
In this research, the modified upconversion nanocrystals NaYF 4 :Yb,Er were adopted as the precursors for the synthesis of the NaYF 4 :Yb,Er@UiO-66 composite. The XRD, XPS and TEM characterizations indicated that the composite has good crystallinity and uniform morphology. Under 980 nm excitation, the NaYF 4 :Yb,Er@UiO-66 composite exhibits bright upconversion emission that characterized of Er 3+ : 2 H 11/2 → 4 I 15/2 , 4 S 3/2 → 4 I 15/2 , and 4 F 9/2 → 4 I 15/2 radiative transitions. After modified with BPEI (branched polyethyleneimine), the NaYF 4 :Yb,Er@UiO-66/BPEI fluorescence probe was constructed and was used for the detection of Cu 2+ . The results revealed that the integrated emission intensity of Er 3+ displayed a linear relationship with the concentration of Cu 2+ within the range of 5 to 45 μM with a LOD of 0.9615 μM. This study offered a feasible method for constructing UCNC@UiO-66 composites with regular morphology,which may have a potential application as fluorescent probes for the detection of various metal ions by adjusting the doping luminescent center.
研究领域:
材料科学
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分析化学
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ETHNOPHARMACOLOGY
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2019
·
IF 3.414
Nani Wang,Pingcui Xu,Xuping Wang,Weixuan Yao,Zhongming Yu,Renjie Wu,Xiaowen Huang,Yuyang Si,Dan Shou
Ethnopharmacological relevance Oxidative damage to osteoblasts was a key factor in the development of osteoporosis. Er-Xian Decotion (EXD) is widely used in China for the treatment of osteoporosis, which has a variety of antioxidant active ingredients. EXD may be an important source of protection against oxidative damage in osteoblasts, but the anti-osteoporotic active components of EXD is currently unclear. Aim of the study This work established an effective and reliable drug screening method to find main active ingredients in EXD (M-EXD) that can protect osteoblasts against oxidative stress and achieve anti-osteoporosis effects. Materials and methods H 2 O 2 -induced osteoblast cell fishing with UHPLC-QTOF/MS was firstly used to discover the potential active components from EXD. Afterword, the EXD compound-osteoporosis target network was constructed using network pharmacology , thus potentially anti-osteoporosis ingredients were founded, and their combination were defined as the M-EXD. Finally, pharmacology effects of M-EXD was evaluated by ovariectomized rats, prednisolone induced-zebrafish and H 2 O 2 -induced osteoblasts. Results 40 candidate active ingredients in EXD were initially screened out via pathological cell fishing. According to network pharmacology result, M-EXD consisted of 13 ingredients since they had a close relationship with 65 osteoporosis-related targets. Pharmacological evaluation showed that M-EXD significantly ameliorated oxidative stress in H 2 O 2 -induced osteoblast model, evidently reversed the activity of ALP , ROS , GSH-px, NO and MDA compared with the model group. M-EXD showed better anti-oxidative activities than individual ingredients, presenting obvious synergetic effects. In osteoporosis rat and zebrafish models, M-EXD also demonstrated good anti-osteoporotic properties by mitigating the osteoporosis bone loss and increasing serum bone morphogenetic protein 2 , and reversing osteocalcin expression in bone tissue. It significantly ameliorated oxidative stress in the in-vivo models. Moreover, M-EXD and EXD showed similar anti-osteoporotic and anti-oxidative properties, while the rest components of EXD had no satisfactory anti-osteoporotic efficacy. Conclusions Our work successfully identified the main active components in EXD, which could represent the efficacy of EXD on treating osteoporosis, and meanwhile, it also provided an effective strategy to investigate active ingredients from natural medicines, which might be helpful for drug development and application.
研究领域:
民族药理学
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药物开发
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生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Electronic Materials
·
2022
·
IF 4.494
Linghui Shen,Tong Wei,Yongchao Shi,Xiangyu Wang,Liwei Wu,Jiao Cui,Tianyang Zhang,Hongzhi Yu,Zepeng Li
Upconversion (UC) luminescence materials with dynamically adjustable activity under external stimuli are of great interest owing to their potential applications in optical storage and high-sensitivity optical switches. Recently, photochromic (PC) effect was considered as an alternate way to regulate the UC luminescence of inorganic materials; however, external-field-induced bleaching was routinely completed by single stimulation, which limited its practical application. In this work, one kind of smart phosphor, Er-activated Bi7Ti4NbO21 intergrowth bismuth layer-structured ceramics that exhibited both intense UC green emission and prominent PC reaction, was synthesized. The UC luminescence, PC effect, and their coupling properties were researched. Interestingly, light–heat and light–light dual-controlled UC luminescence and PC processes were realized. Accompanying the PC effect, the UC luminescence can be reversibly modified by alternating 405 and 532 nm light stimulation (or thermal stimulation). Under 405 nm irradiation, the UC luminescence quenching ratio can reach up to 80.8%. Meanwhile, the UC luminescence raise ratio can respectively reach up to 426.9 and 118.1% under 250 °C thermal treatment and 532 nm light bleaching. The UC luminescence modulation was exposed to be tightly related to the irradiation coloration and thermal/light decoloration processes. Good fatigue resistance of the UC luminescence switching was also achieved. The mechanisms related to the UC luminescence modulation and PC process were discussed. These results indicated that Er-activated Bi7Ti4NbO21 samples can be adopted as a kind of optical data memory materials.
研究领域:
材料科学
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光学工程
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产品关联
DOI
高影响因子
RSC Advances
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2015
·Vol. 5
·期 115
·94980-94985
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IF 3.84
Chuanying Wang,Xianhua Cheng
In this work, amino-functionalized NaYF4:Yb,Er upconversion nanoparticles (UCNPs) were synthesized by a hydrothermal method. Then a simple self-assembly method was carried out to prepare a NaYF4:Yb,Er upconversion (UC) film on a silicon (Si) substrate, using γ-(2,3-epoxypropoxy)propyltrimethoxysilane (KH-560) as an intermediate coupling agent. The chemical composition and surface morphology of the UC film were characterized using X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR), water contact angle (WCA), and scanning electron microscopy (SEM) measurements. Furthermore, the tribological properties of the UC film were investigated by a UMT tester. The results indicate that the UC film has been successfully prepared on the Si substrate by the formation of chemical bonds and its lifetime is about five times longer than that of the NaYF4:Yb,Er UCNPs on a bare Si substrate. This work provides a facile way to synthesize a NaYF4:Yb,Er UC film with robust adhesion to the substrate, which can be applicable for other UC films.
研究领域:
材料科学
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表面工程
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2014
·Vol. 2
·期 38
·6626-6633
·
IF 0
Min Liu,Yuhang Ye,Cheng Yao,Wenbo Zhao,Xiaohua Huang
Chemiluminescence was used as an excitation light source to construct a universal photoelectrochemical platform based on Mn2+-doped NaYF4:Yb/Er upconversion nanoparticles, which greatly improves the electrochemiluminescence intensity and offers more stable cathodic signals compared to pure NaYF4:Yb/Er NPs. Here, we report for the first time the ECL behaviors of Mn2+-doped NaYF4:Yb/Er NPs, which were synthesized via a facile strategy. Mn2+ doping resulted in a 4-fold ECL intensity enhancement of NaYF4:Yb/Er. The characteristics of Mn2+-doped NaYF4:Yb/Er nanocomposites were obtained using transmission electron microscopy (TEM), energy dispersive X-ray spectrometer (EDS), and fluorescence spectra. After all the results had indicated that NaYF4:Yb/Er upconversion nanoparticles were successfully doped with Mn2+, the electrochemiluminescence platform was built. The as-prepared NaYF4:Yb/Er NPs were rendered water-soluble and then employed as ECL emitters for carcinoembryonic antigen (CEA) determination. The results indicated that the modified electrode can be used to determine CEA without interference from non-specific proteins, with a low detection limit of 5.2 pg mL−1. The biosensor can also be used for quantification of the CEA concentration in real samples.
研究领域:
生物医学工程
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纳米医学
✓ 已验证
DOI
PubMed
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Guangdong Wu,Juanqin Xue,Dashi Lei,Yanyan Zhou,Zhaoyuan Cao,Kang Ren,Qiang Bi,Zhihua Leng
Currently, upconversion nanoparticles (UCNPs) based photocatalysts have been extensively developed to improve solar energy utilization. However, the mechanisms underlying interfacial energy migration of upconversion photocatalyst remain unclear. Herein, a promising composite photocatalyst with complementary properties is designed by integrating β -NaGdF 4 :Yb 3+ /Er 3+ (NGFYE), CdS and multi-walled carbon nanotubes (MWCNTs). The morphology, structure and chemical properties of NGFYE@CdS/MWCNTs ternary photocatalyst are characterized. In addition, the existence of Förster resonance energy transfer process in NGFYE@CdS/MWCNTs photocatalysts, i.e., the migration of excitation energy from Er 3+ − 4 S 3/2 excitation level and higher excitation level (e.g., Er 3+ − 2 H 11/2 ) to CdS nanoparticles, was further confirmed by density functional theory (DFT) calculations. The optimized NGFYE@CdS/MWCNTs photocatalyst presents 71.65 % and 35.29 % degradation of tetracycline hydrochloride (TCH) and ciprofloxacin (CIP) under λ ≥ 800 nm irradiation for 3 h, respectively. This work not only illustrates the interfacial energy migration mechanism between NGFYE and CdS, but also provides insights for the rapid construction of heterojunction materials with efficient energy transfer interfaces.
研究领域:
材料科学
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环境科学
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理论化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF TOXICOLOGICAL SCIENCES
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2019
·
IF 1.732
Yuan Chen,Xiaoxiao Fei,Chenqiao Ye,Qinqing Qian,Zhiqiu Ye,Siqi Xie,Jiamin Chen,Mingliao Zhu,Na Ran,Mingsheng Hou,Lin Xu,Zhangsen Yu
In the past few decades, upconversion nanoparticles (abbreviated as UCNPs) have been more widely applied in the biomedical fields, such as in vitro and in vivo upconversion fluorescent bioimaging, photodynamic therapy, biological macromolecular detection, imaging mediated drug delivery and so on. But meanwhile, there is still not much research on the acute toxicity of upconversion nanoparticles in vivo, such as acute hepatotoxicity. In this work, we studied the in vivo biodistribution and acute hepatotoxicity of multimodal targeted contrast agent NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoprobe, which were synthesized by the solvothermal method and modified with Polyethylene glycol (PEG), Polyetherimide (PEI), folic acid (FA) on the surface. The acute hepatotoxicity in mice was systematically assessed after tail vein injection of different concentration of UCNPs. The results showed that NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoparticles with an average diameter of 44.5 ± 10.4 nm, and three typical upconversion fluorescence emission bands at 520 nm, 540 nm and 660 nm under the excitation of 980 nm laser. In vivo distribution experiments results demonstrated that approximately 87% of UCNPs injected through the tail vein accumulate in the liver. In the acute hepatotoxicity test, the intravenously injection dose of UCNPs was 10, 40, 70 and 100 mg/kg, respectively. The body weight, blood routine, serum biochemistry, histomorphology and liver oxidative stress were detected and observed no significant acute hepatotoxicity damage under the injection dose of 100 mg/kg. In conclusion, NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoprobes are safe and reliable, and have potential applications in the field of tumor targeted multimodal imaging.
研究领域:
生物医学工程
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毒理学
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纳米技术
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分子影像
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）