INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2024
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IF 3.8
Yuehua Xiao,Chengtao Wang,Jiale Xiao,Hangjie Li,Zhengxing Cui,Yeqing Wang,Liang Wang,Feng-Shou Xiao
Oligomerization of alkenes is a promising way for production of high-quality and eco-friendly liquid fuels, where zeolite catalysts are critical. In the zeolite catalysts, mass transfer and accessibility in the reaction are normally influenced by intrinsic micropores of zeolites, in particular, bulky or branched molecules are employed. Here, we report isoamylene (2-methyl-2-butene) dimerization over mesoporous HY zeolites obtained by facile NaOH treatments. These mesoporous HY zeolites exhibited high activity and good stability for the isoamylene dimerization compared with untreated HY zeolite. Powder XRD patterns, N2 physisorption, SEM, TEM, NMR, FTIR, and NH3-TPD techniques were used to characterize the porosity and acidity of the zeolites. These results showed that mass transfer and accessibility to the acid sites of the guest molecules are the key factors for the improvement of catalytic performances.
研究领域:
化学工程
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催化材料科学
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DOI
高影响因子
Catalysis Science & Technology
·
2015
·Vol. 5
·期 9
·4602-4612
·
IF 5.426
Feifei Yang,Shuguang Zhang,Z. Conrad Zhang,Jingbo Mao,Shenmin Li,Jingmei Yin,Jinxia Zhou
Biodiesel is a sustainable and environmentally compatible diesel fuel substitute that presents certain limitations, particularly low-temperature flow properties, which are attributable to its long fatty chain structure. Branched alkyl derivates such as tertiary butyl ethers are efficient biodiesel additives for improved cold flow behaviour of biodiesel. In this study, tert-butoxymethylfurfural (tBMF) is synthesised as a biodiesel additive through etherification of 5-hydroxymethylfurfural (5-HMF), a non-edible biomass-derived building block, with isobutene (IB) on a series of acid zeolites and liquid acids. The catalytic activity and selectivity of a zeolite catalyst involve not only optimisation of the number and strength of its acidic sites and adsorption properties but also promotion of its internal pore space. Efficient solvent systems did not include extremely weakly polar or strongly polar solvents but included moderately polar solvents, such as glycol dimethyl ether which presents suitable hydrophilic/hydrophobic properties. The HY zeolite with a SiO2/Al2O3 mole ratio of 12 in combination with glycol dimethyl ether solvent exhibited an excellent tBMF selectivity of 94 mol% with 59 mol% 5-HMF conversion after 3 h of reaction at 60 °C. Side reactions of 5-HMF dimerisation and the IB oligomerisation were minimal under mild reaction conditions. The activity of the deactivated catalyst was fully recovered by calcination in air, and a detailed deactivation mechanism was proposed.
研究领域:
化学工程
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可再生能源
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催化科学
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DOI
高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2024
·
IF 5.9
Shixiong Chen,Jiarong Wang,Jing Zhang,Qinghao Zeng,Hong Jiang,Haiqing Chang,Tian C. Zhang,Xiaobao Tian,Kai Wang,Ying Liang
Surface modification could remarkably improve the oil–water separation ability of membrane, but suffers from limited survival positive effect layer after long-term operation. Herein, we report a systematic comparative study between bulk and surface modification (i.e., synchronous or sequential electrospun/elecrospraying) on hydrophobic polyvinylidene difluoride (PVDF) membrane. A hydrophilic UiO-66-NH 2 @polyacrylic acid micro/nanospheres (UiO@PAA) was selected as functional layer to improve the separation and adsorption capability of PVDF. The surface modification (SMM) and bulk modification membranes (BMM) exhibited the similar water wetting behavior in air as the same surface layer. The spider filament-like nanofibers of BMM could enhance the mechanical stability and dispersion uniformity of active sites among the PVDF fibers. In terms of oil-in-water emulsions separation ability, the BMM was superior to the SMM with the maximumly increase of separation efficiency and filtration flux to 1.3 % and 192.6 L m -2 h −1 , respectively. As for dye absorption, the BMM showed better adsorption capacity with a removal efficiency over 96 %. For the low concentration of methylene blue, the removal efficiency of SMM was only 94 %, while the removal efficiency of the BMM reached 98 % at room temperature. In addition, the BMM exhibited higher removal efficiency over 94 % compared with that less than 84 % of SMM after eight cycling tests, confirming its advantages in repeatability. This study demonstrates that the bulk modification can endow the initial membrane with better performance and durability, showing more promising prospects in actual wastewater treatment.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
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2020
·
IF 1.808
Lili Zhang,Wen Duan,Yan Huang,Yuyu Zhang,Baoguo Sun,Dandan Pu,Yizhuang Tang,Chao Liu
Taste is one of the main chicken soup characteristic quality factors as it affects palatability as well as consumer acceptability. Metabolomics coupled with sensory analysis method were applied to explore the differences of taste-chemical compositions in chicken carcasses and their correlation to the sensory qualities. Results showed that organic acid were the main taste compounds contained in the five kinds of chicken soup samples. The umami taste intensity of chicken breast meat soup was significantly higher than that of the other four parts (p < 0.05). Seven organic acids (oxalic acid, tartaric acid, formic acid, lactic acid, acetic acid, citric acid, and succinic acid) and a small peptide (anserine) were the main differential taste compounds among chicken soup with five different parts, and they contributed significantly to the taste of chicken soup (taste activity value (TAV) >1).
研究领域:
食品科学
·
生物学
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
·
IF 3.8
Jinjin Zhang,Fumin Wang,Xubin Zhang,Yi Zhai,Kaiwei Wang,Changhao Bing,Xiaolu Fan,Xinyuan He,Qi Shen,Linfang Jiang,Jiawei Wang,Zheng Wang
Achieving excellent conversion and high stability is crucial in promoting practical applications of many emerging oxidative desulfurization (ODS) catalysts. Herein, POM@HUSYs were prepared through an in situ procedure, which enhanced the dispersion of polyoxometalate (POM) and reduced the leaching of active components. The catalyst was prepared in an acidic environment, which served a dual purpose. One purpose was to introduce Lewis acid sites in the zeolite, while the other was to synthesize the corresponding POM to provide Bro̷nsted acid sites. By adjusting the synthesis conditions, catalysts with the best synergistic impact between the Lewis and Bro̷nsted acid sites were discovered. The best sample HPW@HUSY24H-0.06M could achieve 99.2% DBT conversion in 120 min. Additionally, the obtained catalyst could efficiently adsorb the ODS products from the oil phase without extraction. The concept of a synergistic catalytic mechanism guides the future design and development of heterogeneous catalysts for ODS reactions.
研究领域:
催化化学
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材料科学
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环境化学
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DOI
高影响因子
JOURNAL OF DRUG TARGETING
·
2025
·
IF 3.9
Ying Fan,Chuli Liao,Jie Li,Meiling Wu,Jie Liu,Feng Li,Wen Wu
Nitric oxide (NO) is essential for wound healing, promoting angiogenesis and collagen deposition. This study investigates a novel dual-matrix nanocomposite hydrogel incorporating S-nitrosoglutathione (GSNO), a physiological NO donor, to enhance cutaneous wound healing. GSNO was encapsulated in ammonio methacrylate copolymer nanoparticles and embedded in an alginate-based matrix, achieving controlled NO release. GSNO-loaded nanoparticles were prepared using solvent displacement and solvent evaporation methods, resulting in spherical, well-distributed, and positively charged particles. These nanoparticles were cross-linked with negatively charged alginic acid to form a nanocomposite hydrogel. The hydrophobic nanoparticles protected GSNO from degradation, while the hydrophilic alginate matrix sustained the release of active GSNO for up to 10 hours, promoting hemostasis and maintaining a moist wound environment. The hydrogel exhibited good biocompatibility in human fibroblasts and significantly enhanced wound repair by promoting fibroblast formation, neovascularization, and collagen deposition, as demonstrated by hematoxylin and eosin staining and Masson’s trichrome staining. In conclusion, the GSNO-loaded nanocomposite hydrogel significantly accelerated the healing process by enhancing angiogenesis and collagen deposition, offering a promising strategy for improving wound healing.
研究领域:
生物材料学
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医学
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药剂学
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DOI
PubMed
高影响因子
CHEMOSPHERE
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2024
·
IF 8.1
Haoyang Liu,Yang Yu,Shengtao Jiang,Haimin Sun,Weixi Zhang,Jianmeng Chen,Dongzhi Chen
The efficient biodegradation of volatile chlorinated hydrocarbons using microbial fuel cells (MFCs) offers a feasible approach for purifying waste gas and alleviating energy crises. However, power generation is limited by poor pollutant biodegradation and slow electron transfer . The bifunctional bacterium Acinetobacter sp. HY-99C was screened and used to improve the performance of a conventional MFC. The inoculation of strain HY-99C into the conventional MFC promoted the formation of a compact biofilm with high metabolic activity and an enriched bifunctional genus ( Acinetobacter ), which resulted in the accelerated decomposition of chlorinated aromatic compounds into biodegradable organic acids. This led to efficient chlorobenzene removal and power generation from the MFC, with a chlorobenzene elimination capacity of 70.8 g m −3 h −1 and power density of 89.6 mW m −2 , which are improved over those of previously reported MFCs. This study provides novel insights into enhancing pollutant removal and power generation in MFCs.
研究领域:
环境科学
·
微生物学
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DOI
PubMed
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2023
·
IF 5.5
Yu Liang,Lanjiang Wang,Xuekuan Li,Mingxing Tang,Qiong Tang,Jinxiang Dong,Lei Liu
Supported Pt catalysts are widely applied for the hydrogenation of polycyclic aromatic hydrocarbons, but it remains a challenge to achieve deep hydrogenation with high atomic utilization. Herein, a novel approach that combines physical vapor deposition with ozonation treatment was developed to construct the highly dispersed Pt on HY zeolite. The high concentration of O 3 was utilized to remove the ligand of acetylacetone platinum under mild condition due to its strong oxidizing properties, which markedly inhibited the aggregation of the Pt species. The hydrogenation of naphthalene and anthracene was investigated on such catalysts and compared with the catalyst prepared by traditional calcination approach, it was found that the co-existence of Pt single-atom and cluster on HY of 1Pt/HY-O 3 exhibited significantly high catalytic performance in the hydrogenation of naphthalene and anthracene, which was beneficiated from the synergistic effect of Pt single-atoms and clusters on HY support.
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高影响因子
FUEL
·
2024
·
IF 6.7
Qiuxiang Yao,Lei He,Duo Ma,Yong Zhang,Dan Zhang,Ming Sun
The naphthalene derivatives in coal tar naphthalene and anthracene oil fractions mostly contain short-chain alkyl groups. The enrichment of PAHs (polycyclic aromatic hydrocarbons, mainly including naphthalene, anthracene, and pyrene) by the dealkylation of PAHs-rich fraction in coal tar was assumed to obtain high-purity PAHs by distillation. Based on this strategy, using 2-methylnaphthalene as the model compound, and the influences of catalysts with different supports (SiO 2 , Al 2 O 3 , ZSM-5, Beta, and HY) and different active metal components (Ni, Co, Mo, and W) prepared by the equivalent-volume impregnation method on the hydro-dealkylation performance of 2-methylnaphthalene under different technological conditions (temperature, H 2 initial pressure and reaction time) were systematically investigated in a pressurized batch reactor. The experimental results show that the conversion rate of 2-methylnaphthalene is 81.23 % and the selectivity of naphthalene is 64.22 % under conditions of 480 °C, 2 MPa, 4 h, and 6 W-HY. Loading 0.8 wt% La on the 6 W-HY catalyst can improve the dispersion of active metal component W on the support, but it does not change the skeleton structure of the support. In addition, one-dimensional diffusion is the most probable reaction mechanism for 2-methylnaphthalene, and the evolution profiles of naphthalene can be reflected by the reaction mechanism with a reaction order of n = 4 using the model fitting method.
研究领域:
化学工程
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催化
·
石油化学
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DOI
高影响因子
PHARMACEUTICAL RESEARCH
·
2026
·
IF 4.1
Mo Jiajia,He Emily M.,Zhao Yan,Shao Li,Yue Shaoyun,Xie Yanmei,Wu Shiqi,He Jianxun,Zou Yi,Chu Zhaoxing,He Guangwei,Xu Yungen
Purpose Patients with acute coronary syndrome (ACS) require rapid and potent antiplatelet therapy during percutaneous coronary intervention (PCI). Current first-line P2Y₁₂ inhibitors are limited by delayed efficacy or an ultrashort half-life. This study aims to characterize the metabolism and pharmacodynamics of HY-022619, a disodium phosphate ester salt of ticagrelor, to provide a theoretical basis for its clinical use in peri-PCI antithrombotic therapy. Methods The inhibitory activity of HY-022619 against the P2Y₁₂ receptor and ADP-induced platelet aggregation was evaluated in vitro . Molecular docking was performed to compare its receptor-binding mode with ticagrelor. Metabolic stability was assessed in whole blood, liver microsomes, and using recombinant enzymes. Pharmacodynamic profiles were investigated in rats and beagle dogs, with additional assessments of metabolic conversion and bleeding time in dogs. Results HY-022619 showed 22-fold greater P2Y₁₂ receptor inhibition and 15-fold stronger suppression of platelet aggregation than ticagrelor. Molecular docking revealed that enhanced activity was due to an additional salt bridge. HY-022619 remained stable in human and non-rodent whole blood (half-life > 60 min) and was primarily hydrolysed to ticagrelor in the liver by CES1 and CES2. In rats, intravenous administration produced rapid, dose-dependent platelet inhibition within 5 min. In dogs, HY-022619 acted rapidly with efficacy peaking at the end of infusion. It converted completely to ticagrelor within 5 min post-infusion, maintaining antiplatelet effects for 6 h, without significantly prolonging bleeding time compared to ticagrelor. Conclusion HY-022619 demonstrates rapid, potent, and sustained antiplatelet effects, supporting its potential clinical application. Graphical
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PubMed
高影响因子
ENERGY & FUELS
·
2026
·Vol. 40
·期 30
·16618-16630
·
IF 6
Zhang Jing,Liu Fang-Jing,Xia Lei,Wang Meng-Jie,Xia Wei-Zhen,Zhao Mei-Xia,Zhao Yun-Peng,Zhong Mei,Wei Xian-Yong
Selective cleavage of stable C–C bridging bonds
in the macromolecular
framework of low-rank coal is crucial for its mild conversion to aromatics.
Herein, a bifunctional CoMoS/HY catalyst, featuring highly dispersed
CoMoS nanosheets anchored on ordered HY channels (3–4 nm),
was successfully constructed for the selective hydrocracking of low-rank
coal. Strong metal–support interactions stabilize surface Mo
species and enrich weak acid sites. The weak Lewis acid sites are
primarily responsible for driving the polarization and activation
of C–C bridging bonds. Consequently, the incorporation of HY
remarkably boosts intrinsic activity, giving outstanding turnover
frequencies (TOF) of 85.4 h –1 for Mo and 89.7 h –1 for acid sites (both three times higher than unsupported
CoMoS). Under mild conditions (270 ° C, 2 MPa H 2 , 3
h), the catalyst achieved 98.70% diphenylmethane conversion with >96%
selectivity for arenes. When applied to catalytic hydrocracking of
residue from the thermal dissolution of Naomaohu coal, it produced
a liquid oil yield of 37.2 wt %, which is more than five times higher
than that of the noncatalytic hydrocracking, while also demonstrating
deoxygenation and coke suppression capabilities. This work highlights
a metal–acid-driven synergistic pathway for the efficient conversion
of low-rank coal into high-value arenes.
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高影响因子
FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Weifang Yang,Youyou Yang,Liang Wang,Xueze Lv,Jing Li,Huanxian Cui,Chaohua Tang,Qingyu Zhao,Yaxiong Jia,Yuchang Qin,Junmin Zhang
Eggs are nutritious and highly valued by consumers. However, egg flavor varies greatly among different hen breeds. The present study used gas chromatography-olfactometry-mass spectrometry-based volatilomics to identify and compare volatile compounds in Taihe black-boned silky fowl (TS) and Hy-line Brown (HL) egg yolks. In addition, the relationships between the levels of different metabolites and lipids and flavor-associated differences were investigated using multiomics. Twenty-eight odorants in total were identified; among them, the levels of 3-methyl-butanal, 1-octen-3-ol, 2-pentylfuran, and (E, E)-2,4-decadienal differed significantly ( P < 0.05) between TS and HL egg yolks. The difference in flavor compounds results in TS egg yolks having a stronger overall odor and flavor and a higher acceptance level than HL egg yolks. Metabolomic analysis revealed that 112 metabolites in the egg yolks were significantly different between the two breeds. Furthermore, these different metabolites in the egg yolks of both breeds were significantly enriched in phenylalanine , tyrosine , and tryptophan biosynthesis pathways and phenylalanine metabolism, alanine , aspartate, and glutamate metabolism pathways ( P < 0.05), as identified by both metabolite set enrichment and Kyoto Encyclopedia of Genes and Genomes pathway analyses. Lipidomic analysis revealed significant differences in the lipid subclasses, lipid molecules, and fatty acid profiles between the egg yolks from the two breeds. As a result, 48 lipid molecules had variable influence in projection values > 1 based on the partial least squares regression model, which may play a role in the differences in aroma characteristics between the two breeds through oxidative degradation of fatty acids. Our study revealed the metabolite, lipid, and volatility profiles of TS and HL egg yolks and may provide an important basis for improving egg flavor to satisfy various consumer preferences.
研究领域:
食品科学
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农学
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畜牧学
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分析化学
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营养学
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DOI
PubMed
高影响因子
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