BIOELECTROCHEMISTRY
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2025
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IF 4.5
Runran Ma,Te Li,Xueying Li,Jianwei Han,Xin Zhang,Tingting Di,Jiabo Wang,Weijun Kong
A ratiometric electrochemical aptasensor was developed for ultra-sensitive detection of cortisol using aptamer (Apt) as recognition element, methylene blue (MB) as signal probe, and zirconium metal–organic framework (Zr-MOF) as carrier loaded with abundant MB for signal amplification. The carboxylated multi-walled carbon nanotubes (cMWCNTs)-modified Au electrode showed excellent electrochemical performance to immobilize complementary DNA (cDNA) for hybridizing with MB@Zr-MOF-Apt via amide bonds. In the presence of cortisol, it would compete with cDNA for binding the Apt, resulting in the detachment of MB@Zr-MOF-Apt complex from the electrode surface, and the electrochemical signal of MB was decreased, while that of [Fe(CN) 6 ] 3−/4− was basically unchanged. The ratio of the electrochemical signals of [Fe(CN) 6 ] 3−/4− to MB was proportional to the cortisol concentration. Due to the greatly enhanced conductivity of the cMWCNTs-decorated Au electrode and the largely improved EC signals of Zr-MOF encapsulated MB probes, this ratiometric electrochemical aptasensor offered high sensitivity with an ultra-low detection limit of 0.0046 nM and a wide linearity of 0.01–1000 nM, as well as satisfactory accuracy with recoveries of 93.79–106.76 % in artificial sweat samples, providing a potential strategy for the detection of more trace hormones in different clinical samples by simply replacing the corresponding aptamers.
研究领域:
分析化学
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生物医学工程
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DOI
PubMed
高影响因子
Processes
·
2025
·Vol. 13
·期 1
·253
·
IF 2.8
Sitong Liu,Shicheng Liu,Letao Li,Letong Yang,Xiaodong Wu,Zhichun Si,Rui Ran,Hui Wu
In this study, a combination of calcination and hydrothermal methods was employed to synthesize a honeycomb-like ZnO/g-C3N5(ZCN) heterojunction in situ. The ZCN heterojunction photocatalyst exhibits remarkable photocatalytic degradation performance, achieving a 97% methyl blue (MB) degradation rate with the rate constant of 0.0433 min−1(almost twice that of ZnO). Optical performance tests reveal that the ZCN heterojunction broadens the absorption edge to 710 nm and enhances the charge carrier separation. The presence of abundant oxygen vacancies, as revealed by X-ray photoelectron spectroscopy analysis, effectively suppresses the recombination of photogenerated electron–hole pairs. Furthermore, density functional theory simulations indicate that the combination of ZnO and g-C3N5creates an internal electric field due to their differing work functions. This leads to the formation of a Z-scheme heterojunction that effectively suppresses charge carrier recombination and preserves the strong redox capabilities of ZnO and g-C3N5. Finally, electron spin resonance results indicate thatO2−and OH are the primary active radicals involved in the degradation process. This study introduces a potential approach for the development of highly efficient Z-scheme photocatalysts for water treatment applications.
研究领域:
材料科学
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环境科学
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光催化
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DOI
高影响因子
CHEMICAL PHYSICS LETTERS
·
2024
·
IF 2.8
Shokir Khojiev,Gulmira Khojieva,Dan Chen,Jun Chen,Hemdan S.H. Mohamed,Jing Liu,Yu Li
In this study, red-emissive carbon quantum dots (R-CQDs) were synthesized using a simple, one-step solvothermal method with 1,3-naphthalenediol as the carbon source. The synthesized R-CQDs were thoroughly characterized in terms of morphology, crystallinity, functional groups, optical, and photocatalytic properties. The R-CQDs exhibited an average particle size of 5 nm, with functional groups aiding in their uniform dispersion in water. Raman spectra revealed the presence of both D and G bands, indicating successful construction of a sp 2 core and sp 3 hybridized matrix. The R-CQDs showed strong absorption at 512 nm and high emission intensity at 610 nm. Additionally, the R-CQDs demonstrated exceptional photocatalytic performance, achieving 96 % methylene blue degradation in 180 min, with a calculated rate constant of 0.0167 min −1 . Their stability across different pH levels further underscores their potential as efficient photocatalysts in a variety of environmental applications.
研究领域:
材料科学
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环境科学
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DOI
高影响因子
LANGMUIR
·
2025
·
IF 3.9
JunZheng Chen,Xue Lv,Yanmin Ma,Wang Xu,Shurui Yi,Di Fang
Photocatalytic technology has attracted great attention in environmental treatment in recent years due to its environmental friendliness. However, the commonly used photocatalyst TiO2 cannot effectively utilize visible light due to its wide bandgap, and the difficulty in recycling the powder catalyst limits the further development of photocatalysis. In this paper, we report a novel PVDF membrane loaded with TiO2/GN/Ag NWs for photocatalytic degradation of MB dye wastewater in the presence of SA by simple vacuum filtration of the photocatalysts loaded on the PVDF membrane, the addition of GN and Ag NWs successfully shortened the band gap of the PVDF/SA/TiO2 membrane (3.2 eV) to that of the PVDF/GN/SA/TiO2/Ag12 membrane (2.6 eV), which effectively enlarged the utilization of TiO2 for visible light and demonstrated efficient and stable photocatalytic degradation of MB dye wastewater under simulated sunlight, and furthermore, the removal efficiency of MB dye wastewater was still maintained at 86% after 5 cycles. This work provides a possibility for the application of TiO2-based PVDF membranes in the photocatalytic degradation of dye wastewater.
研究领域:
环境科学
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材料科学
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化学工程
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纳米技术
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DOI
PubMed
高影响因子
Frontiers in Pharmacology
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2022
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IF 5.988
Ming Ying,Qin Li,Jingbo Wu,Yihang Jiang,Zhourui Xu,Mingze Ma,Gaixia Xu
Breast cancer is characterized by the uncontrolled proliferation of breast epithelial cells under the action of a variety of carcinogens. Although HER2-inhibitors were currently applied for HER2-positive breast cancer patients, they didn’t work for patients with resistance to HER2-targeted anti-cancer drugs. In this work, we prepared novel CuS@BSA-NB2 nanoparticles (NPs) for breast cancer photothermal therapy (PTT). The NPs had good biocompatibility due to the Bovine Serum Albumin (BSA) encapsulating and excellent targeting to HER2 because of nanobody 2 (NB2). Under 808 nm laser irradiation, CuS@BSA-NB2 NPs had high photothermal conversion efficiency and photothermal stability. Meanwhile, we constructed a stable cell line of MDA-MB-231/HER2 with a high expression of HER2 protein. Immunofluorescence and ICP-MS assays showed that CuS@BSA-NB2 NPs can be specifically enriched and be ingested in MDA-MB-231/HER2 cells. Furthermore, CuS@BSA-NB2 NPs had shown a more significant photothermal treatment effect than CuS@BSA under certain treatment conditions for MDA-MB-231/HER2. In addition, the cytotoxicity assay demonstrated that CuS@BSA-NB2 NPs had a low toxicity for MDA-MB-231/HER2 cells. The above results suggested that CuS@BSA-NB2 NPs were great photothermal therapeutic agents to reduce the malignant proliferation of breast epithelial cells and have potential for breast cancer therapy.Keywords: CuS@BSA-NB2 nanoparticles, photothermal therapy, HER2, NB2, MDA-MB-231/HER2
研究领域:
癌症研究
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纳米技术
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治疗学
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产品关联
DOI
PubMed
高影响因子
BIORESOURCE TECHNOLOGY
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2020
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IF 7.539
Shuang Xu,Jihui Li,Zhibing Yin,Sen Liu,Siyao Bian,Yucang Zhang
Fenton modification, involving iron-promoted pyrolysis followed by H 2 O 2 oxidation, was first employed to improve the adsorptive and magnetic capabilities of biochar. Modified biochars were prepared from rubber tree bark and coconut shell through iron-promoted pyrolysis and subsequent H 2 O 2 oxidation, and their adsorption behaviors toward Cr (VI) and MB were evaluated in aqueous solution. The modified biochars pyrolyzed at 300 and 400 ˚C displayed much higher adsorption capabilities than corresponding pristine biochars for Cr (VI) and MB, respectively, ascribing to introduction of COOH, C O and C–O groups by Fenton oxidation. More importantly, saturation magnetization could be enhanced by transforming nonmagnetic iron oxides into γ-Fe 2 O 3 through H 2 O 2 oxidation. The removal of Cr (VI) and MB could be primarily contributed to the adsorption of biochar matrix by reduction/hydrogen bonding/cation exchange/electrostatic interaction and hydrogen bonding/cation exchange/electrostatic interaction, respectively. This would provide a novel and efficient strategy for making highly adsorptive magnetic biochar.
研究领域:
环境科学
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材料科学
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DOI
PubMed
高影响因子
TALANTA
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2026
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IF 6.7
Yuhan Fu,Shu Wang,Jihui Hu,Yadong Zhou,Chunlian Zhan,Lin Yin,Yan Long Meng
An indirect surface-enhanced Raman spectroscopy (SERS) approach based on an MB-Mo-AgNPs probe system was developed to quantify aqueous KH 2 PO 4 standard solutions. Silver nanoparticles (AgNPs), methylene blue (MB), and ammonium molybdate served as the SERS substrate, Raman reporter, and phosphate-responsive reagent, respectively. All concentrations were expressed as KH 2 PO 4 mass concentrations. Across 0.0625–10 mg L −1 KH 2 PO 4 , the MB bands near 1400, 1470, and 1626 cm −1 decreased with increasing concentration. UV–Vis spectroscopy, qualitative dried-state transmission electron microscopy, dynamic light scattering, and zeta-potential measurements supported changes in the probe’s colloidal state, particle association, and interfacial environment, consistent with a possible indirect signal-modulation pathway. These measurements did not establish a specific molecular mechanism or demonstrate MB desorption. The dataset comprised 2040 spectra from 51 independently prepared physical samples at 17 concentrations. In physical-sample-level grouped training–validation–test rotations, the 40 replicate spectra per sample remained within one subset, preventing sample overlap. Single-peak linear regression was compared with full-spectrum partial least squares regression, support vector regression (SVR), a conventional one-dimensional convolutional neural network (1D-CNN), and an attention-enhanced 1D-CNN. The full-spectrum models yielded lower errors than single-peak linear calibration. SVR achieved the lowest quantitative error among the compared models, with an RMSE of 0.0072 ± 0.0010 mg L −1 across three grouped rotations. In the prespecified grouped analysis, the attention-enhanced 1D-CNN yielded lower quantitative error than the conventional 1D-CNN. The results apply only to aqueous KH 2 PO 4 standard solutions and do not validate total-phosphorus determination, real-wastewater analysis, or performance in external matrices.
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DOI
高影响因子
JOURNAL OF POLYMERS AND THE ENVIRONMENT
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2023
·Vol. 31
·期 7
·2999-3014
·
IF 5.3
Song Jie,Chen Lijun,Niu Yuhua,Wei Zhiqiang,Sun Yonghui
From the perspective of environmental protection, high removal rate, reusable and degradable, amino-functionalized porous hydrogel material P-(EA-β-CD/KHA/AC) was synthesized by introducing ethylamino cyclodextrin, humic acid, and activated carbon, using polyacrylic acid as the carrier. MB and Cr (VI) are common wastewater pollutants, thus, Such contaminants must be removed from the water. The gel materials before and after adsorption were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. The removal of MB and Cr(VI) showed high adsorption capacity. At 298 K and pH 8, the adsorption capacities of P-(EA-β-CD/KHA/AC) hydrogel for MB and Cr(VI) were as high as 262.31 and 170.12 mg/g, respectively, and the removal rates were 98.96% and 70.27%, respectively. The adsorption behavior follows the pseudo-second-order kinetic equation, conforming to the Langmuir model; and through intermolecular forces, π–π conjugation, chelation, and other interactions, entropy-increasing, endothermic, and spontaneous process is formed. The regeneration and degradability experiments of P-(EA-β-CD/KHA/AC) hydrogel were conducted and its recycling performance was verified.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
POLYMER DEGRADATION AND STABILITY
·
2022
·
IF 5.204
Qingkun Liu,Peng Wei,Chuanbo Cong,Xiaoyu Meng,Qiong Zhou
A novel antioxidant denoted as HVA-2@MB was synthesized through the reaction of N,N'-1,3-phenylene bismaleimide (HVA-2) and 2-mercaptobenzimidazole (MB) catalyzed by triethylamine. This antioxidant had high molecular weight as well as crosslinking and antioxidation functions. Then, the effect of HVA-2@MB on the crosslinking and antioxidation behaviors of ethylene-propylene-diene rubber (EPDM) was investigated. HVA-2@MB greatly reduced the inhibitory effect of antioxidants on rubber vulcanization and improved the crosslinking density of rubber. In addition, due to the reactivity of HVA-2@MB, the antioxidant groups were chemically bonded to the rubber network, which significantly reduced the migration of antioxidants in the thermo-oxidative environment, thereby improving the thermo-oxidative stability of the rubber. Therefore, compared with MB/EPDM composites, HVA-2@MB/EPDM composites exhibited better mechanical properties and thermo-oxidative stability during thermo-oxidative aging.
研究领域:
材料科学
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高分子化学
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DOI
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Yi Fang,Lang Yang,Feng Rao,Yongming Zheng,Zhenguo Song
In this study, a low-cost porous geopolymers (PGP) were prepared using coal gangue and fly ash as raw materials to remove organic and heavy metal ions from wastewater. Various characterization techniques were employed to investigate the microstructure, morphology, pore size distribution, and surface functional groups of the porous geopolymers. The results indicate that the geopolymer exhibits a porous structure with hydroxyl groups on the surface after foaming. It was found that the porous geopolymers exhibited good adsorption capacity for Methylene Blue (MB), Cu(II), and Pb(II), with optimal adsorption capacities reaching 35.60 mg/g, 98.31 mg/g, and 85.67 mg/g, respectively. Fitting analysis suggests that the adsorption of MB, Cu(II), and Pb(II) is better described by the pseudo-second-order kinetic model and the Freundlich isotherm model. This indicates that the adsorption process is primarily chemical adsorption with multilayer adsorption. Competitive adsorption studies showed that Cu(II) could enhance the adsorption of MB, while Pb(II) had no significant effect on the adsorption of MB. Mechanistic studies revealed that the adsorption of MB by PGP is mainly through pore adsorption, electrostatic attraction, and hydrogen bond formation; whereas the adsorption of Cu(II) and Pb(II) is primarily through pore adsorption, electrostatic attraction, chemical reactions, and ion exchange. Recycling experiments demonstrated that after five repetitions, the adsorption capacity of PGP for the three pollutants remained above 60 %. These findings confirm the potential of porous geopolymers as adsorbents. Preliminary cost analysis shows that the adsorption cost of porous geopolymers is only 2.07 RMB/kg, making the geopolymer adsorbent economically advantageous and promising for application, especially considering its ability to utilize industrial solid waste.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yonggang Du,Yongfei Zhu,Jiayi Li,Yuxuan Li,Jianrui Xiao
Biodegradable and low-cost superhydrophobic absorption materials are still urgently required for the removal of organic compounds from sewage. In this study, sugarcane bagasse (SCB), an abundant and readily available byproduct from sugarcane industries, was used as substrate to fabricate the superhydrophobic adsorbent through a facile dip-coating technique. Firstly, β-FeOOH particles were in-situ grown on the SCB surface, which was further decorated with SiO 2 particles. Next, the modified SCB were coated with benzoxazine based on cardanol and dodecylamine (C D) followed by a thermal curing to obtain a superhydrophobic SCB (PC-D/β-FeOOH@SiO 2 /SCB) with a water contact angle (WCA) of 154°. PC-D/β-FeOOH@SiO 2 /SCB not only exhibited excellent oil absorption capacities in the range of 11.8 to 22.6 g/g for various organic solvents and oils, but also could successfully separate immiscible oil-water mixtures and emulsions with a separation efficiency of over 99.1 %. After 30 cycles of use, the absorption capacity of the modified SCB only displayed a slight decrease and its separation efficiencies for immiscible oil-water mixture, water-in-oil and oil-in-water emulsions are all more than 99.2 %, meanwhile, all these repeatedly used SCB still maintained a superhydrophobicity, demonstrating an outstanding reusability. Moreover, the WCA of PC-D/β-FeOOH@SiO 2 /SCB was still higher than 150 o after 48 h of immersion in HCl, NaOH and NaCl solutions, exhibiting a satisfactory chemical stability. Besides, the prepared SCB also possessed a high photocatalytic degradation activity to methylene blue. Therefore, this work not only provides a sustainable and cheap superhydrophobic absorbent for wastewater treatment, but also presents a route for the better utilization of SCB.
研究领域:
材料科学
·
环境科学
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产品关联
DOI
PubMed
高影响因子
EUROPEAN POLYMER JOURNAL
·
2018
·
IF 3.741
Ruoyun Li,Linbo Wu,Bo-Geng Li
PEG-mb-PBAT (EB, for simplicity) multiblock copolymers were synthesized via chain extension/coupling of poly(ethylene glycol) (PEG) and poly(butylene adipate-co-terephthalate) (PBAT) diols, and used as modifiers to prepare blends of commercial poly( l -lactide) (PLLA) and EB via melt blending. The EB copolymers were characterized by 1 H NMR and DSC, and the PLLA70/EB30 blends were characterized by DSC, SEM, tensile and impact testing. The PEG segments in EB show greatly depressed crystallization as compared with PEG prepolymer, therefore, exhibit excellent plasticization effect on PLLA. Furthermore, they also compatibilize the PBAT microphase with PLLA matrix. Owing to strong interfacial adhesion, the PBAT micro-phases induces highly oriented shear yielding during impact process and therefore act as efficient tougheners of PLLA. Therefore, the blends possess highly improved toughness (impact strength 44 kJ/m 2 ) and excellent ductility (elongation 160%), and at the same time, retain sufficient stiffness. Furthermore, the L/EB blends show superior mechanical performances than the L/EP (PLLA/PEG-mb-PPA) blends reported by us previously.
研究领域:
材料科学
·
高分子化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）