FOOD HYDROCOLLOIDS
·
2023
·
IF 10.7
Yue Zhang,Shiyu Yang,W. James Hardie,Xue Li,Muyan Xiao,Tao Huang,Tao Xiong,Mingyong Xie
Plant essential oils (EO) are increasingly used as food preservatives due to their antibacterial and antioxidant activities . For such applications, EO are commonly microencapsulated to overcome their poor stability, low solubility and dominant aromas. But, typically, individual EO act against only a narrow range of bacterial species. Therefore, in this study, we aimed to develop a microencapsulated preservative using a combination of three EO and to determine its anti-bacterial action against three common food contaminants, viz. Escherichia coli , Salmonella and Staphylococcus aureus , and one, usually, beneficial species, viz. Lactoplantibacillus plantarum . The EO of cinnamon ( Cinnamomum cassia ), peppermint ( Mentha haplocalyx ) and lemon ( Citrus limon) were combined in the proportions, 1.0 : 1.8: 2.4, respectively and were encapsulated in gelatin-chitosan by spray drying. The particle size, zeta potential , moisture content, and encapsulation rate of the essential oil microcapsules (EOM) were measured. With increasing EOM exposure time, the concentrations of E. coli , Salmonella , S. aureus and L. plantarum decreased by 3, 3, 4, and 5 orders of magnitude, respectively. Cell apoptosis accompanied loss of membrane integrity and permeability, inhibition of lactate dehydrogenase activity and disruption of organic acid metabolism. Gram-positive bacteria ( S. aureus and L. plantarum ) were more susceptible to those effects of EOM than Gram-negative bacteria ( E. coli and Salmonella ). It also demonstrates that in applications as preservatives for probiotic foods requiring live L. plantarum , EOM comprising cinnamon, peppermint or lemon EO should be avoided.
研究领域:
食品科学
·
微生物学
·
药学
·
化学工程
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DOI
高影响因子
Acta Pharmaceutica Sinica B
·
2023
·
IF 14.5
Zinan Zhang,Wenbin Cao,Huanchun Xing,Shuai Guo,Lijuan Huang,Lin Wang,Xin Sui,Kui Lu,Yuan Luo,Yongan Wang,Jun Yang
In the treatment of central nervous system disease, the blood–brain barrier (BBB) is a major obstruction to drug delivery that must be overcome. In this study, we propose a brain-targeted delivery strategy based on selective opening of the BBB. This strategy allows some simple bare nanoparticles to enter the brain when mixed with special opening material; however, the BBB still maintains the ability to completely block molecules from passing through. Based on the screening of BBB opening and matrix delivery materials, we determined that phospholipase A2-catalyzed 1-palmitoyl-2-oleoyl- sn -glycero-3-phosphoserine liposomes can efficiently carry drugs into the brain immediately. At an effective dose, this delivery system is safe, especially with its effect on the BBB being reversible. This mix & act delivery system has a simple structure and rapid preparation, making it a strong potential candidate for drug delivery across the BBB.
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PubMed
高影响因子
JOURNAL OF MATERIALS IN CIVIL ENGINEERING
·
2026
·Vol. 38
·期 6
·04026111
·
IF 3.2
Kuan Li,Jianguang Xie,Zhixiang Zhang,Yangwei Tan,Lei Feng
To address the contradiction between high-temperature construction retention time and normal-temperature curing time of hot mix epoxy asphalt (HEA), in this paper, 2,4,6–tris (dimethylaminomethyl) phenol (TAP) was selected as the accelerator, and the viscosity–time–temperature (VTT) characteristics and the curing rate of the HEA were modulated by varying the accelerator dosage. The VTT characteristics of the HEA during the paving–rolling stage were quantitatively characterized by a rheometer for the first time, and the effect of accelerator dosages and thermal histories on the VTT characteristics of the HEA during the mixing–rolling stage were systematically analyzed. Additionally, the effect of the accelerator dosages on the morphology, curing rate, and mechanical properties of the HEA were thoroughly assessed. The incorporation of accelerator can effectively decrease the reaction activation energy of the hot mix epoxy resin (HER) while maintaining the reaction order without significant alteration. The viscosity of both HER and HEA during the mixing–rolling stage can be precisely regulated by adjusting the dosage of the TAP. Due to the dilution effect of the matrix asphalt, the VTT characteristics of HEA are markedly diminished under varying thermal history conditions when compared with HER, thereby facilitating on-site construction control. The incorporation of an appropriate quantity of accelerator effectively mitigates the coalescence behavior between the epoxy phase and the asphalt phase, thereby substantially enhancing the microstructural homogeneity of the HEA. As the dosage of the accelerator progressively increases from 0% to 2%, both the tensile strength and loss factor of HEA exhibit a trend of initially increasing rapidly and subsequently leveling off gradually. This study is expected to enhance the characterization and regulation of the workability of the epoxy asphalt throughout the construction process.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2014
·
IF 4.058
Songyan Jia,Zhanwei Xu,Z.Conrad Zhang
The production of 5-Hydroxymethylfurfural (HMF) from hexoses is a stoichiometric dehydration process. Water content in a solvent is expected to play an important role in HMF formation by affecting the equilibrium and the reaction kinetics. In this work, the impact of water content on the catalytic conversion of glucose was investigated in detail in different dimethylsulfoxide (DMSO)/H 2 O mixtures ( χ w = 0–1) with chromium trichloride hexahydrate (CrCl 3 ·6H 2 O) as the catalyst at 110–130 °C. Water content in the binary mix was found to dominantly affect the product distribution. Anhydrous DMSO system is favored for HMF formation from glucose but caused a number of side reactions, especially the undesired dehydration of glucose into cellobiose. Adding an appropriate amount of water in DMSO ( χ w = 0.17–0.50) was found to significantly suppress the undesired dehydration side reactions while preserving high HMF yield over the CrCl 3 ·6H 2 O catalyst, therefore remarkably improving the total selectivity of HMF and fructose from glucose conversion. While CrCl 3 ·6H 2 O was essential in isomerizing glucose into fructose, hydrochloric acid (HCl) from CrCl 3 ·6H 2 O hydrolysis in DMSO/H 2 O mixed system catalyzed the dehydration of in situ formed fructose to HMF. Although effective water removal was pronounced toward improving HMF yield from hexose dehydration in previous work, the results of this work indicate that a controlled amount of water in the non-aqueous system is favorable to drive the thermodynamic equilibrium for high HMF yield and desired product selectivity, providing reference information on designing a one-pot process for HMF synthesis from cellulosic materials.
研究领域:
化学工程
·
生物化学
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DOI
高影响因子
Environmental Technology & Innovation
·
2023
·
IF 7.1
Yining Ji,Na Zheng,Bo Wu,Qirui An,Zimeng Li,Siyu Sun,Wenhui Zhang,Xiaoqian Li,Sujing Wang
A novel adsorbent was synthesized for the capture of heavy metals mixture in water by encapsulating hydroxyapatite-modified wood ear mushroom sticks biochar in calcium alginate beads (CA-HAP MB ). The surface structure and adsorption mechanism of the CA-HAP MB were characterized by Scanning electron microscopy and X-ray energy dispersion spectroscopy (SEM-EDS), Fourier transform infrared spectrometer (FTIR), X-ray diffraction patterns (XRD), and X-ray photoelectron spectroscopy (XPS). Under different conditions, CA-HAP MB for Cd 2 + and Pb 2 + were investigated for their adsorption properties in water and their competition. The adsorption capacities of Cd 2 + and Pb 2 + on the aerogel spheres reached 302.2 mg g −1 (2.69 mmol g −1 ) and 564.5 mg g −1 (2.73 mmol g −1 ), respectively (based on Langmuir). The aerogel spheres are easier to collect than biochar materials. The results show that CA-HAP MB composite aerogel spheres have a good application prospect in capturing heavy metal ions from water.
研究领域:
环境科学
·
材料科学
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DOI
高影响因子
Surfaces and Interfaces
·
2024
·
IF 5.7
Guoqiang Zhang,Diandian Shi,Zhiqi Wang,Jianqing Li,Tao He,Jingli Wu,Jinhu Wu
The high-dispersed nano complex ZnO/Co 3 O 4 was first prepared by calcining the ZIF-8@ZIF-67 in Air. Then, the ternary mix-heterojunction ZnIn 2 S 4 /CdIn 2 S 4 /Co 3 O 4 (CdIn 2 S 4 /Z/C) was first in situ constructed by introducing nano complex ZnO/Co 3 O 4 into the CdIn 2 S 4 precursor solution via a solvent thermal reaction. Overall, the CdIn 2 S 4 /Z/C photocatalyst exhibits excellent performance in the photoconversion of CO 2 and H 2 O, which increased by 18.1%∼34.1% for CO, 36.8%∼73.9% for H 2 , and 21.1%∼40.6% for syngas (CO+H 2 ), respectively, compared with CdIn 2 S 4 . The CdIn 2 S 4 /Z/C-40 shows the highest H 2 -evolution rate of 1661.8 μmolg −1 h −1 , which is 87.5% higher than that of CdIn 2 S 4 (886.3 μmolg −1 h −1 ). The CdIn 2 S 4 /Z/C exhibits higher surface S-vacancy concentration, larger specific surface area, stronger light absorption, and photocurrent density than that of CdIn 2 S 4 . The band structure reveals that the ZnIn 2 S 4 /CdIn 2 S 4 /Co 3 O 4 forms a tandem internal electric field at the double heterojunction interface, which is beneficial to improve the migration of photocarrier. This work provides a feasible strategy for constructing synergistic mix-heterojunction photocatalyst for photoconversion of CO 2 and H 2 O.
研究领域:
材料科学
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环境科学
·
能源科学
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Xiaoming Ma,Shan He,Huifang Zhang,Xun Li,Jun Xue,Xiaolin Fan,Yusheng Lu,Yiting Chen,Yanjie Zhang,Jianguo Xu
Herein, we have designed a unique oligonucleotide probe named as bumped switchable molecular probe (BS-MB) and employ it to ultrasensitive detection of miRNA-21. The uniqueness is that the bumped portion renders the BS-MB great design flexibility and divides its long stem into two short stems so that it can play the roles of recognition unit, reporting unit, and polymerization primer and template simultaneously. The opening of BS-MB requires a delayed reaction, allowing the system a better-suppressed background without miRNA-21. In contrast, the introduction of miRNA-21 delayed the full opening of BS-MB, inducing a concurrent three-stage amplification for consuming lots of BS-MBs in one amplification event. During the amplification, lots of target analogues of extended miRNA-21 (E-miRNA-21) and cleavaged miRNA-21 (C-miRNA-21) that can be reused as miRNA-21 to cause further fluorescence enhancement are repeatedly generated. The system retains the simplicity (one oligonucleotide probe) and simplifies the detection procedure (one-step detection). Its mix-to-signaling and one-to-many amplification behaviors are superior to conventional MB based amplification, exhibiting a wide linear response and a low detection limit of 8.1 fM. High specificity against even one-base mutation, desirable recovery rates for testing miRNA-spiked serum samples, and well-defined accuracy for classifying clinically related samples are also demonstrated.
研究领域:
分子生物学
·
生物化学
·
纳米技术
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分析化学
·
生物医学工程
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
·
IF 5.2
Haopeng Zhang,Shisong Ren,Yanjun Qiu
The ethylene-vinyl acetate (EVA) polymers are always doped into waxy bitumen to inhibit network of wax crystals in bitumen. However, the compatibility improvement behaviors between wax-based warm mix (WWM) additives and bitumen by EVA are not clear, and the sustainable components of EVA for corresponding WWM additives to achieve better compatibility improvement are also not determined. This paper investigated compatibility improvement behaviors between commonly used WWM additives and bitumen after the addition of EVA to obtain sustainable components of EVA through experimental method of activation energy of viscous flow (AEVF) and density function theory-molecular dynamic (DFT-MD) calculations. The results show that the repulsions between the end of main-chain with highest electronegativity in WWM additives and polar molecules of EVA can alleviate the aggregation behaviors of WWM additives and EVA displays the best and worst compatibility improvements for additives with shortest and longest carbon chains, respectively. The dispersed asphaltenes combined with EVA can form the composite wax inhibitors (WIs) systems to increase diffusion coefficient and reduce percentage increment values of cohesive energy density (CED) to further disrupt ordered degree of WWM additives. On this basis, the sustainable carbon numbers of main-chain for EVA that are slightly less than average carbon numbers of WWM additives will help to better improve the compatibility of WWM additives. This investigation can provide the inspiration on how to choose the sustainable components of EVA to achieve high-efficiency compatibility improvement for corresponding warm mix asphalts (WMAs) with different average carbon numbers.
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
Materials
·
2025
·Vol. 18
·期 12
·2740
·
IF 3.2
Xin Jin,Shanshan Meng,Haoxuan Fu,Qi Zhao,Deli Li,Zhuolin Li,Ye Yang,Yanhai Yang,Jiupeng Zhang,Qingyue Zhou
Warm-mix recycled asphalt (WMA-R) technology for reclaimed asphalt pavement (RAP) significantly reduces energy consumption and environmental pollution while maintaining the performance of asphalt mixtures. Significant progress has been made at home and abroad in evaluating the impact of regenerated asphalt mixtures on the performance of regenerated asphalt. However, the performance improvement of WMA-R depends on the effective diffusion of regenerated agents and their interaction mechanism with aged asphalt, which has not been fully studied. This paper systematically studies the diffusion characteristics of biomimetic-based warm-mix regenerant in aged asphalt and its impact on the high- and low-temperature performance of asphalt mixtures through MD and experimental verification. The results show that biomimetic-based warm-mix regenerant can significantly improve the diffusion performance of aged asphalt. Through the rutting test and low-temperature bending test, the significant improvement of the biomimetic-based warm-mix regenerant in the rutting resistance and crack resistance of asphalt mixtures was verified.
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高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Rui Zeng,Ying Liu,Yue Lu,Chao Chang,Jine Wu
In order to overcome the technical challenges of poor stability and weak antibacterial effects of individual essential oil in food preservation applications, the present study aimed to encapsulate cinnamon and clove essential oil compound by using spray-drying technique. The combination of cinnamon and clove essential oils was determined to have good synergistic bacteriostatic effects by the checkerboard dilution method, and the best bacteriostatic effect could be obtained when the volume ratio was 7:3 for compounding. Microcapsules were prepared using hydroxypropyl-β-cyclodextrin (HPCD) as wall material and compound essential oil as core material, the optimal conditions for the microcapsule preparation process through a one-way test were: homogenizing speed of 8000 r/min, wall material addition of 2 %, HPCD to EO ratio of 1:3, EO to T-80 ratio of 1.5:1, and homogenizing time of 8 min. The physicochemical properties of the prepared compound essential oil microcapsules (EOM) were characterized, and the results showed that the EOM was successfully encapsulated in HPCD with good physicochemical properties, and the encapsulation rate of the prepared microcapsules was measured to be 65.82 ± 4.00 %. The thermal stability of the encapsulated EOM was improved, and volatilization of the essential oils was effectively inhibited. In addition, the EOM showed antibacterial activity against the five types of bacteria tested, and the number of surviving bacteria decreased by about 17–18 % after 72 h. The preservation experiment of low salt pickles showed that the EOM was more effective in maintaining the quality and prolonging the shelf life of the pickles compared with commercial sodium benzoate, which also demonstrated the potential application of EOM in preserving low-salt pickles. This study provides a feasible and new technical strategy for more effective application of plant essential oils in food preservation.
研究领域:
食品科学
·
植物化学
·
微生物学
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DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2019
·
IF 14.229
Munir Ahmad,Xie Quan,Shuo Chen,Hongtao Yu
Iron containing MOFs have been currently estimated as greater candidates for heterogeneous Fenton catalysts due to their open pores and well dispersed metallic components. However, metals in majority of MOFs are bounded by organic linkers, which reduces Lewis acid sites and make them not available for H 2 O 2 activation. Creating coordinatively unsaturated metal centers (CUCs), acting as Lewis acid sites, is a feasible approach for efficient photo-Fenton activity. Here, we successfully synthesized a photo-Fenton CUCs-MIL-88B-Fe catalyst with mixed-valence (Fe II /Fe III ) on ultrathin Ti 3 C 2 nanosheets. The Lewis acidity was probed by TPD-NH 3 and IR-pyridine analysis and tested for pollutants degradation. The results showed that CUCs-MIL-88B-Fe/Ti 3 C 2 displayed highest photo-Fenton activity under visible light irradiation at pH 3.0 and 10 mM H 2 O 2 . This could be attributed with the CUCs, fast H 2 O 2 activation, high Lewis acidity and carrier separation with Ti 3 C 2 nanosheets due to its high charge mobility. Furthermore, CUCs-MIL-88B-Fe/Ti 3 C 2 exhibited a good stability and reusability.
研究领域:
材料科学
·
环境科学
·
化学工程
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产品关联
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Qian Luo,Nan Ding,Hongxiu Chen,Yaqin Zhang,Miao Zhang,Wenli Gao,Yuanhua Li,Kejun Feng,Xingbo Shi
Effective identification of sulfur ions (S 2- ) in foodstuff is crucial for food safety and human health, but it remains challenging. Traditional single-mode colorimetric sensing methods are simple and sensitive, but are prone to interference from colored substances which can lead to false positives or negatives results. Herein, we develop a novel “mix-response” biosensor for colorimetric and photothermal dual-mode detection of S 2- with good simplicity, sensitivity and portability. In this biosensor, silver-doping Prussian blue nanoparticle (SPB NPs) was used as signal output component, which not only exhibits blue color characteristics, but also has photothermal conversion properties activated by near-infrared (NIR) laser. Upon increasing the S 2- concentration, the prepared SPB NPs undergo etching, leading to the formation of new silver sulfide precipitation (Ag 2 S), along with different colorimetric and photothermal response signals. For the portable visualization of S 2- , the color information was recorded by a smartphone in combination with RGB (red channel) analysis and the evolution of the photothermal signal was documented by a thermal imager. The introduction of smartphone and handheld thermal imager in this “mix-response” biosensor makes it suitable for on-site quantitative detection of S 2- without sophisticated instrument. Moreover, the development of this “mix-response” biosensor does not need the use of recognition probes (e.g. aptamers and reaction intermediates), thereby simplifying the construct procedures of sensing strategies and improving the economic efficiency of detection. More importantly, the photothermal response signals can overcome the interference of colored substances in foods, thereby reducing the false positives or negatives of the detection results.
研究领域:
分析化学
·
食品科学
·
纳米技术
·
生物技术
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）