ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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2022
·Vol. 29
·期 27
·40734-40744
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IF 5.19
Zhu Bo,Xu Jiangyan,Xu Zhihui,Wu Meisheng,Jiang Hongmei
A facile soft-template solvent thermal strategy was developed to prepare mesoporous carbon–silica composite (MMCS) by using furfuryl alcohol (FA) as carbon precursor, Pluronic copolymer P123 as template, hydrated iron nitrate as iron source, and teraethylorthosilicate as silicon source and it was applied for the removal of methyl orange (MO). The as-synthesized MMCS with abound of hydrophilic groups processed a high specific surface area, large pore volume, and good magnetic response. With the increased amount of FA, the surface area and functional groups increased, promoting the adsorption effect. The maximum adsorption capacity of MO on MMCS can be high to 113.1 mg g −1 at pH 4 with 150 mg L −1 initial MO concentration. The adsorption isotherm, kinetic, and thermodynamics were all studied and the results showed the adsorption process well fitted Langmuir adsorption isotherm and pseudo-second-order model. Additionally, it was shown that the adsorption process could not be interfered by the co-existence of PO 4 3− , NO 3 − , CO 3 2− , SO 4 2− , and real water matrix. And the proposed adsorbent can remove MO in three practical water samples with satisfied removal rates ranging from 92.8 to 99.8%. Thus, the MMCS prepared in this study could be utilized as an alternative adsorbent for the removal of methyl orange from practical aqueous solution.
研究领域:
材料科学
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环境科学
·
化学工程
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产品关联
DOI
PubMed
高影响因子
Theranostics
·
2019
·
IF 8.063
Zhongyuan Chen,Yueting Peng,Xiaoxue Xie,Yi Feng,Tingting Li,Shun Li,Xiang Qin,Hong Yang,Chunhui Wu,Chuan Zheng,Jie Zhu,Fengming You,Yiyao Liu
Background & Aims : The use of antisense oligonucleotide-based nanosystems for the detection and regulation of tumor-related gene expression is thought to be a promising approach for cancer diagnostics and therapies. Herein, we report that a cubic-shaped iron oxide nanoparticle (IONC) core nanobeacon is capable of delivering an HSP90α mRNA-specific molecular beacon (HSP90-MB) into living cells and enhancing T 2 -weighted MR imaging in a tumor model. Methods : The nanobeacons were built with IONC, generation 4 poly(amidoamine) dendrimer (G4 PAMAM), Pluronic P123 (P123) and HSP90-MB labeled with a quencher (BHQ1) and a fluorophore (Alexa Fluor 488). Results : After internalization by malignant cells overexpressing HSP90α, the fluorescence of the nanobeacon was recovered, thus distinguishing cancer cells from normal cells. Meanwhile, MB-mRNA hybridization led to enzyme activity that degraded DNA/RNA hybrids and resulted in downregulation of HSP90α at both the mRNA and protein levels. Furthermore, the T 2 -weighted MR imaging ability of the nanobeacons was increased after PAMAM and P123 modification, which exhibited good biocompatibility and hemocompatibility. Conclusions : The nanobeacons show promise for applicability to tumor-related mRNA detection, regulation and multiscale imaging in the fields of cancer diagnostics and therapeutics.
研究领域:
纳米技术
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生物医学工程
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癌症研究
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分子生物学
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医学成像
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产品关联
DOI
PubMed
高影响因子
Small
·
2024
·
IF 13
Guanqing Zhang,Fengqing Liu,Qiliang Zhu,Hao Qian,Shouchao Zhong,Jingze Tan,Anmin Zheng,Fujian Liu,Lilong Jiang
Herein, a variety of 2,6-diaminopyridine (DAP) derived nitrogen-doped hierarchically porous carbon (DAP-NHPC-T) prepared from carbonization-induced structure transformation of DAP-Zn-SiO 2 -P123 nanocomposites are reported, which are facilely prepared from solvent-free co-assembly of block copolymer templates P123 with pyridine-rich monomer of DAP, Zn(NO 3 ) 2 and tetramethoxysilane. In the pyrolysis process, P123 and SiO 2 templates promote the formation of mesoporous and supermicroporous structures in the DAP-NHPC-T, while high-temperature volatilization of Zn contributed to generation of micropores. The DAP-NHPC-T possess large BET surface areas (≈956–1126 m 2 g −1 ), hierarchical porosity with micro-supermicro-mesoporous feature and high nitrogen contents (≈10.44–5.99 at%) with tunable density of pyridine-based nitrogen sites (≈5.99–3.32 at%), exhibiting good accessibility and reinforced interaction with SO 2 . Consequently, the DAP-NHPC-T show high SO 2 capacity (14.7 mmol g −1 , 25 °C and 1.0 bar) and SO 2 /CO 2 /N 2 IAST selectivities, extraordinary dynamic breakthrough separation efficiency and cycling stability, far beyond any other reported nitrogen-doped metal-free carbon. As verified by in situ spectroscopy and theoretical calculations, the pyridine-based nitrogen sites of the DAP-NHPC-T boost SO 2 adsorption via the unique charge transfer, the adsorption mechanism and reaction model have been finally clarified.
研究领域:
材料科学
·
化学工程
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
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