FUEL PROCESSING TECHNOLOGY
·
2023
·
IF 7.5
Miaomiao Zheng,Shanshan Yu,Rongguang Yang,Jianbin Liu,Linfeng Zhang,Fuqing Zhang,Huadong Wu,Jia Guo
The electronic structure and hydrophobicity of heterogeneous catalysts are of great importance to catalytic performance. A novel catalyst of functionalized PCN-777-supported Lindqvist-type polyoxometalate derivatives was designed and prepared. The hydrophobicity of the catalyst was improved by simple surface modification. The catalyst was applied in the ODS of dibenzothiophene (DBT) in this study, and the support and catalyst were characterized by Fourier transform infrared (FT-IR), contact angle test , and other methods. Systematic characterization and ODS experiments further confirmed the electron-donating effect of functionalized PCN-777 (tBu-PCN-777) with high hydrophobicity on [C 12 Py] 3 (NH 4 ) 3 Mo 7 O 24. The electron-donating effect leads to a narrow bandgap and high electron density of Mo active sites, ensuring that the catalyst [C 12 Py] 3 (NH 4 ) 3 Mo 7 O 24 /tBu-PCN-777-35% exhibits excellent ODS activity. In particular, [C 12 Py] 3 (NH 4 ) 3 Mo 7 O 24 /tBu-PCN-777-35% completely removed DBT at 60 °C in 50 min, and it continued to be stable after 30 cycles. The sulfur removal efficiency of real diesel oil reached 92.26%. This study demonstrates that functionalized PCN-777 has desulfurization potential and provides new ideas for increasing ODS catalytic activity from the design of electron-donating effect and hydrophobicity.
研究领域:
催化化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Electrochemical Science
·
2023
·
IF 1.5
Mengli Xu,Yuan Shen,Linyu Wang,Coucong Gong,Shouhui Chen
In this work, a novel H 2 O 2 biosensor was developed based on the composites of microperoxidase-11 (MP-11) encapsulated in graphene oxide (GO)-PCN-333 (Al) (PCN stands for porous coordination network, one of the metal-organic frameworks). The PCN-333(Al) firmly and uniformly grew on the surface of GO sheet with large specific surface and excellent electrical conductivity, which provided a lots of pores for the encapsulation of MP-11 in the composites and selectively accumulated analytes into its mesopores to improve the selectivity of enzymatic reaction. The MP-11 molecules might freely move through mesopores of PCN-333 (Al) to maintain bioactivity, which remarkably enhanced the mass transfer rate and quickened the electron transfer for electrochemical biosensors. Scanning electron microscopy was used to characterize the GO and PCN-333(Al)-GO composites. Cyclic voltammetry and differential pulse voltammetry were used to characterize the electrochemical behaviors and performance of the H 2 O 2 biosensor. The target electrode showed excellent performance with a wide linear range from 10 μ M to 800 μ M, a low detection limit of 3 μ M, good stability and high selectivity, which was superior to some other H 2 O 2 biosensors.
研究领域:
生物化学
·
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Environmental Science-Nano
·
2018
·Vol. 6
·期 1
·207-215
·
IF 6.087
Miao Peng,Guijian Guan,Hong Deng,Bin Han,Chen Tian,Junyang Zhuang,Yunyun Xu,Weizhen Liu,Zhang Lin
Considering p-arsanilic acid (p-ASA) as an organoarsenic pollutant, monitoring concentration of p-ASA is significant to maintain environmental security. Photoelectrochemical (PEC) detection is promisingly applied in environmental monitoring for its lower cost and simpler operation, compared to traditional techniques. However, general electrode materials of PEC sensors need to be modified with biological probes due to lack of specific binding sites to analytes, which may lead to complicated sensor fabrication and bio-recognizers inactivation during storage. Herein, a porphyrinic metal–organic framework/reduced graphene oxide (PCN-224/rGO) nanocomposite with simultaneously excellent photoelectric activity and strong binding characteristics was prepared and used to fabricate a PEC sensor for p-ASA detection avoiding the modification of bio-recognizers. Benefiting from the high conductivity of rGO, the separation efficiency of charge carriers was improved in PCN-224/rGO and thereby photocurrent gained an amplification of about 12 times. The PCN-224/rGO nanocomposite had strong affinity to p-ASA via Zr–O–As coordination and π–π stacking. Significantly, the binding of p-ASA could adjust the band position of PCN-224/rGO and facilitate oxygen reduction by releasing more photogenerated electrons, achieving photocurrent enhancement. The developed PEC sensor had a wide detection range, from 10 ng L−1 to 10 mg L−1, with a detection limit of 5.47 ng L−1. Furthermore, the sensor was successfully applied to monitor p-ASA in simulated natural water and swine manure lixivium. This study paved the way for the design of more efficient PEC sensors for environmental monitoring.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
·
2022
·
IF 7.926
Jinjuan Xue,Meng Yuan,Jiamin Gao,Zewu Zhang,Mingxin Wang,Shuaishuai Ma
In this work, a novel PCN-222 metal−organic framework based multitasking membrane was developed for separation of emulsified oils as well as photo-Fenton degradation of refractory aromatic pollutants and inactivation of pathogenic bacteria in water. Fe(III)@PCN-222 nanorods were prepared via impregnation method and subjected to amino-modification, and then robustly anchored on polydopamine (PDA) decorated PVDF membrane via catechol-amine reaction. The as-prepared N-Fe(III)@PCN-222/PDA/PVDF composite membrane exhibited underwater superoleophobicity, and showed high separation efficiency (above 99.4 %) as well as relatively favorable permeation flux (874.9–1592.3 Lm −2 h −1 ) in the separation of emulsified oils ranged from nanoscale to microscale from water. Meanwhile, the membrane serving as a recyclable photo-Fenton platform showed an extensive degradation capacity towards aromatic contaminants and high inactivation activity against bacteria under visible light. The grafted Fe(III) is used as an electron acceptor to promote the separation of photo-generated charge carriers, adjusted the band structure to shorten the bandgap value, and can be reduced to Fe(II) by photo-generated electrons as a Fenton-like catalyst. The photo-Fenton mechanism was studied in detail from the aspects of photoelectric properties, band structure and reactive oxygen species . This work could promote the application of PCN subclass MOFs based superwetting membrane as a recyclable platform for complex wastewater treatment .
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
RARE METALS
·
2025
·
IF 11
Fan Siyu,Xu Tianxi,Yang Hui,Ge Yan,Wang Genlin,Ohno Teruhisa,Xu Bin
In this study, a novel Ce-based metal–organic framework (Ce–OFDC) was synthesized via the hydrothermal method. To enhance its photocatalytic antimicrobial properties, polymeric carbon nitride (PCN) was incorporated into the Ce-OFDC matrix, forming a Ce-OFDC/PCN composite material. Antibacterial assays demonstrated that Ce-OFDC/PCN had significant inhibitory effects on both Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ), achieving inhibition rates of 99.5% and 94.3%, respectively. Notably, the antibacterial performance of Ce-OFDC/PCN was superior to that of Ce-OFDC or PCN alone. Furthermore, photocurrent and electrical impedance scanning measurements demonstrated that the Ce-OFDC/PCN composites showed improved photocurrent response and superior efficiency in separating photogenerated electrons and holes. The photocurrent density of Ce-OFDC/PCN reached 120 μA cm −2 , which was 1.5 times higher than that of PCN (80 μA cm −2 ) and 12 times higher than that of Ce-OFDC (10 μA cm −2 ). Electron paramagnetic resonance analysis indicated that reactive oxygen species played a crucial role in the antimicrobial process, with superoxide radicals (·O 2 − ) and hydroxyl radical (·OH) showing the most prominent influence. We conducted reactive oxygen species (ROS) scavenging experiments to further confirm this view. After adding glutathione (GSH) to remove all ROS, the antibacterial efficiency of Ce-OFDC/PCN decreased by about 40%. Adding D-mannitol to remove ·OH reduced the inhibition rate to 54.7%, and adding superoxide dismutase (SOD) to remove ·O 2 − reduced the inhibition rate to 65.4%. The Ce-OFDC/PCN heterostructure increased the separation efficiency of photogenerated electrons and holes, producing increased reactive oxygen species. That, in turn, contributed to the observed superior photocatalytic antibacterial performance. This research significantly advanced the development of metal–organic framework (MOF)-based materials and provided valuable insights into the design of antimicrobial photocatalysts. Graphic abstract
研究领域:
材料科学
·
环境科学
·
纳米技术
·
化学工程
·
微生物学
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Siqi Chen,Tingting Li,Donglian Deng,Yibing Ji,Ruijun Li
This work innovatively integrated the peroxidase-mimicking activity and red emission property of Fe@PCN-222 framework, designed a cascade reaction system for dual-mode glucose sensing. The Fe 3+ doping significantly improved the catalytic activity of Fe@PCN-222 that can oxidize the substrate o -phenylenediamine (OPD) to generate diminophenazine (DAP) with emission at 566 nm in the presence of H 2 O 2 . Similarly, the Fe@PCN-222 was used to catalyze the colorless TMB to produce blue oxidized TMB (oxTMB) showed absorption at 652 nm. When coupled with glucose oxidase (GOx), the linear ranges of ratiometric fluorescence mode and colorimetric mode for glucose sensing were 1–100 and 10–300 μM, respectively. And the limits of detection (LOD) of 0.78 and 2.41 μM for two modes were obtained, respectively. In addition, the practicability of Fe@PCN-222 nanozyme-based cascade reaction system for detection of glucose in human serum and saliva samples was successfully investigated. It is of great importance to integrate more functions into one skeleton to achieve dual-mode and optimal-performance sensing for expanding potential applications.
研究领域:
生物化学
·
医学诊断
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2025
·
IF 10.5
Haizhi Huang,Hefei Wang,Keyu Du,Xiaoping Yu,Xuping Shentu
Lateral flow immunoassay (LFIA) is an affordable and rapid technique for detecting veterinary drugs such as sulfonamides (SAs). However, balancing accuracy, sensitivity, and convenience remains a challenge. To address this, a microfluidic chip-based LFIA utilizing a zirconium-based organic framework, PCN-222@liposome, was developed to simultaneously detect four Sas: sulfamethizole, sulfamethoxazole, sulfamethoxydiazine, and sulfathiazole, with both colorimetric and fluorescent dual-signal detection. In this study, PCN-222 was modified with liposomes to enhance its biocompatibility and water solubility. Characterization through scanning electron microscopy, transmission electron microscopy, powder X-ray diffraction, and Fourier-transform infrared spectroscopy, confirmed the successful incorporation of liposomes with PCN-222. Under optimized conditions, the PCN-222@liposome-LFIA demonstrated high sensitivity, with detection limits ranging from 0.01 to 0.05 μg/L using fluorescent signals—10 times more sensitive than conventional gold nanoparticle-based LFIA. Finally, the PCN-222@liposome-LFIA integrated with the microfluidic chip successfully detected the four SAs in chicken, shrimp, and milk samples, with recoveries ranging from 89.65 % to 118.78 %. This study presents a simple, sensitive, and efficient method for the rapid detection of veterinary drug residues.
研究领域:
分析化学
·
兽医学
·
纳米技术
·
食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Peide An,Defeng Hu,Yide Han,Hao Meng,Xia Zhang
On accounting of the structure advantages of MOFs in the enzyme mimics and enzyme immobilization, in this work, the Hemin@PCN-222 (Mn) is constructed through an in-situ hydrothermal route by covalently bonded the –COOH of Hemin with the Zr(IV) of PCN-222 (Mn). With the help of the synergistic effects, the resulting Hemin@PCN-222 (Mn) represents excellent peroxidase-like activities in comparison with the single Hemin and PCN-222 (Mn) with a special enzyme activity of 6.71 U mg −1 . The Hemin@PCN-222 (Mn) was then employed as a carrier to immobilize the glucose oxidase (GOx), the immobilization conditions were optimized. Based on that, the optimized GOx@hemin@PCN-222 (Mn) was applied in the following cascade reaction: the glucose oxidation in the presence of oxygen catalyzed by the immobilized GOx firstly, and then the produced H 2 O 2 worked as an oxidant to oxidize ABTS. The quantity of produced ABTS + was monitored to assess the catalytic efficiency, and the contrast experiments were conducted over the mixture of the natural GOx and HRP. The above cascade process could also be used to detect the glucose, and the detection limit is determined. The high efficiency and the stability of the resulting GOx@hemin@PCN-222 (Mn) highlights the prospect applications of the MOFs-based enzyme mimics in the bio-catalysis and biosensing.
研究领域:
生物化学
·
催化
·
生物传感器
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ACTA PHARMACOLOGICA SINICA
·
2022
·Vol. 44
·期 1
·169-177
·
IF 7.169
Zhang Yi-fei,Gao Yue,Yang Jie,Jiang Yi-ming,Huang Min,Fan Shi-cheng,Bi Hui-chang
Pregnane X receptor (PXR) is highly expressed in the liver and plays a pivotal role in xenobiotic and endobiotic metabolism. We previously reported that PXR activation by its specific mouse agonist pregnenolone 16α-carbonitrile (PCN) significantly induces liver enlargement and lipid accumulation. However, the effect of long-term PCN treatment on PXR and mouse liver is still unknown. This study aimed to explore the influence of long-term administration of PCN on mouse liver and hepatic lipid homeostasis. Male C57BL/6 mice were injected intraperitoneally with PCN (100 mg/kg once a week) for 42 weeks. Serum and liver samples were collected for biochemical and histological analysis. PXR activation was investigated by Western blot. Ultra-high-performance liquid chromatography coupled with electrospray ionization high-resolution mass spectrometry (UHPLC-ESI-HRMS)-based lipidomics analysis was performed to explore the change in different lipid categories. The results showed that long-term treatment with PCN significantly promoted hepatomegaly without hepatocyte proliferation and enlargement. Long-term treatment with PCN did not upregulate PXR target proteins in mice, and there was no significant upregulation of CYP3A11, CYP2B10, UGT1A1, MRP2, or MRP4. Lipidomics analysis showed obvious hepatic lipid accumulation in the PCN-treated mice, and the most significant change was found in triglycerides (TGs). Additionally, long-term treatment with PCN had no risk for carcinogenesis. These findings demonstrated that long-term PCN treatment induces hepatomegaly and lipid accumulation without hepatocyte proliferation or enlargement.
研究领域:
药理学
·
毒理学
·
肝病学
·
脂质代谢
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Yani Liu,Haoyu Chen,Lin Chai,Jing Liu,Shu Huang,Feng Liu,Xiaohua Zhu,Youyu Zhang,Meiling Liu,Shouzhuo Yao
The emergence of various nanozymes has revolutionized approaches to detecting total antioxidant capacity (TAC) in food and biological samples; however, the precise quantification of specific antioxidant species such as ascorbic acid (AA) and glutathione (GSH) continue to present significant challenges. Inspired by the functional characteristics of oxidoreductases, we have developed Cu-CeO₂ nanoparticles adorned PCN-224, which exhibit multiple mimetic behaviors, including oxidase (OXD), ascorbate oxidase (AAO), and glutathione peroxidase (GPx)-like activities. This innovative PCN-224@Cu-CeO 2 is designed for the quantitative evaluation of TAC in food, pharmaceuticals, and biological samples. Simultaneously, it enables the accurate determination of AA and GSH levels with favorable selectivity. The integration of nanozymes onto metal-organic frameworks significantly enhances both stability and catalytic efficiency. Furthermore, utilizing the multi-mimetics activity of the same materials simplifies the biosensing processes for TAC and individual antioxidants in tablets, beverages, fruits, and cells, thereby considerably diminishing experimental intricacy. Our findings not only advance the development and applications of novel nanozymes with exceptional multi-mimetic properties but also tackle selectivity challenges associated with colorimetric detection platforms that rely on oxidase and peroxidase activities.
研究领域:
生物化学
·
食品科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Min Xie,Qiaozhen Xu,Tao Lv,Hong Liu
The search for effective and highly selective photocatalysts for CO 2 transformation is exceptionally desirable yet challenging. Herein, a novel BiVO 4 @PCN-224(Cu) heterostructure was constructed by growing BiVO 4 nanosheets on the surface of PCN-224(Cu) rods for visible-light-driven CO 2 photoreduction. The obtained BiVO 4 @PCN-224(Cu) heterostructure could selectively reduce CO 2 into CO in the absence of sacrificial reagents. The CO yield over the optimized sample reached 70.5 μmol g −1 h −1 (corresponding to an apparent quantum yield of 0.42% at 450 nm), a 5.1-fold increase over pristine PCN-224(Cu). The boosted activity of the hybrid could be credited to the S-scheme heterojunction formed at the interface of PCN-224(Cu) and BiVO 4 , which facilitated the separation of photogenerated charges and ameliorated the redox capability. In-situ XPS and hydroxyl radical determination confirmed the S-scheme charge transfer mode. This study provides a new strategy for constructing S-scheme heterojunctions involving metalloporphyrin-based metal-organic frameworks for high-performance CO 2 conversion.
研究领域:
材料科学
·
环境科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2023
·
IF 22.1
Desen Zhou,Xuan Zhang,Zheng Li,Jun Zhang,Tielin Wang,Shaowen Cao
Photocatalytic conversion of CO 2 to usable fuels provides a new strategy for solving energy problems and the greenhouse effect. Porphyrin-based metal-organic frameworks (MOFs) are promising in photocatalysis due to their remarkable light harvesting ability, and the metal active site and its coordination environment can be further adjusted to achieve the high activity. In this work, g-C 3 N 4 /PCN-222 composites with different porphyrin metal centers were fabricated and the g-C 3 N 4 /PCN-222(Fe III ) catalyst showed the highest photocatalytic CO 2 reduction performance than that of g-C 3 N 4 /PCN-222(Fe II ) and other g-C 3 N 4 /PCN-222( M , M = Co, Ni, Cu, Zn) composites. Experimental studies and theoretical calculations showed that the axial coordination in g-C 3 N 4 /PCN-222(Fe III ) distorts the square planar field (Fe-N4) to quasi-octahedral coordination, which led to the moderate adsorption ability of CO 2 reduction intermediate (*CO), resulting in the high photocatalytic activity.
研究领域:
材料科学
·
环境科学
·
化学工程
·
催化
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）