COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
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IF 4.9
Libo Sun,Qingtai Xie,Heshun Jing,Jindong Xie,Wenyu Tan,Baorong Duan,Xun Sun,Caixia Qi,Huijuan Su
The development of nanogold catalysts with high activity and high stability is of great significance for their industrial applications. In this paper, Au-PDA@Fe 3 O 4 catalysts were prepared through the gold sol adsorption method. First, micron-sized magnetic Fe 3 O 4 spheres were synthesized via a solvothermal method, serving as the core to endow the catalyst with excellent recyclability. Subsequently, a layer of polydopamine (PDA) shell was polymerized on the magnetic core surface. By controlling the timing of introducing the gold sol containing Au nanoparticles (NPs), the spatial position of Au NPs within the PDA layer was regulated, leading to a series of magnetic core-shell nano gold catalysts with varying spatial positions of Au. Using the 4-nitrophenol (4-NP) hydrogenation as the probe, the influence of Au spatial position, Au size, and other conditions on the catalytic performance was investigated. Results showed that, in the prepared Au-PDA@Fe 3 O 4 -16 catalyst, the Au NPs are encapsulated within the PDA shell and positioned close to the outer layer. This not only provides remarkable stability to the Au NPs but also maintains their proximity to the surface of the PDA shell, allowing easier access of the substrate 4-NP to the Au NPs and conferring good reactivity upon the catalyst. The strong electron metal-support interaction between PDA and Au enables PDA to effectively stabilize Au NPs. The prepared Au-PDA@Fe 3 O 4 -16 catalyst exhibits excellent stability, maintaining a high conversion rate of 91 % even after 14 cycles of use. Our findings not only deepen the understanding of the catalytic mechanisms involved but also pave the path towards the creation of highly efficient and robust gold-based catalysts, facilitating their widespread utilization in industrial applications.
研究领域:
材料科学
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催化化学
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Bioengineering and Biotechnology
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2022
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IF 6.064
Zhang Yifei,Ning Rende,Wang Wei,Zhou Yejin,Chen Yao
Osteosarcomas commonly develop in the metaphysis of the long diaphysis, resulting in pronounced malignancy and high rates of early pulmonary metastasis. At present, osteosarcoma patients exhibit relatively poor survival rates owing these metastases and to the emergence of tumor chemoresistance. As such, there is an urgent need to identify other approaches to treating affected patients. Herein, we synthesized Fe3O4@PDA nanocomposites that exhibited excellent biocompatibility and low toxicity in human and animal model systems. The resultant nanoparticles were able to improve T2 magnetic resonance imaging and to enhance the signal-to-noise ratio associated with osteosarcoma tumors in animal models. Moreover, we were able to successfully leverage these Fe3O4@PDA particles as a photothermal agent capable of significantly inhibiting the growth of tumors and preventing their metastasis to the lung compartment. Together, these results highlight a novel therapeutic platform that has the potential to guide both the more effective diagnosis and treatment of osteosarcoma patients in clinical applications.
研究领域:
医学影像学
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肿瘤学
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纳米医学
✓ 已验证
DOI
高影响因子
Energies
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2020
·Vol. 13
·期 6
·1484
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IF 2.702
Honghai Wang,Yifan Lu,Hongli Liu,Yi Yin,Jun Liang
A magnetic nano-solid acid catalyst Fe3O4-PDA-SO3H was synthetized through an efficient method, as an eco-friendly and more efficient catalyst. The obtained catalyst has uniform core-shell structure, appropriate particle size, and high acid density. Fe3O4-PDA-SO3H was applied to catalyze the esterification of levulinic acid (LA) with alcohols of different chain length to produce the levulinate esters. The catalytic effect was optimized from the aspects of catalyst dosage, reaction temperature, and acid-alcohol molar ratio. Furthermore, the response surface optimization method was used to obtain the optimal conditions. Verified under these conditions, the experimental results showed that the conversion rate of LA can reach 95.87%, which was much higher than common cationic exchange resin Amberlyst 36 and Amberlyst 46. Furthermore, the recovery and reuse of the Fe3O4-PDA-SO3H was demonstrated six times without obvious loss in the activity.
研究领域:
化学工程
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材料科学
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催化化学
✓ 已验证
DOI
高影响因子
CHEMICAL PHYSICS LETTERS
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2025
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IF 3.1
Simin Li,Ziran Chang,Fengbing Tang,Tianshuo Sui,Lemin Li,Jingbo Mu,Zhennan Shi
The QS@PDA/Co-Mn-ZIF catalyst, synthesized using quartz sand as a base material, effectively degrades TCH through the activation of PMS. The Co-Mn-ZIF component activates PMS, while PDA ensures the adhesion of ZIF to quartz, facilitating catalyst recovery. This design enhances electron transport and metal ion redox reactions, generating reactive species that degrade TCH. It achieves a 94 % TCH removal rate from a 100 mg/L solution within 40 min, demonstrating stability under various pH and water conditions. The catalytic mechanism was elucidated·through radical trapping experiments and electron paramagnetic resonance analysis. QS@PDA/Co-Mn-ZIF shows great potential for treating recalcitrant and high-concentration organic wastewater.
研究领域:
环境科学
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催化化学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
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2019
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IF 5.256
Heng Zhang,Zhen Wang,Xiaoqing Yang,Zi-Long Li,Linhao Sun,Jimei Ma,Hong Jiang
A sensitive nanocomplex probe prepared from fluorescent polydopamine nanoparticles (F-PDA) and cobalt oxyhydroxide (CoOOH) nanosheets was established for the determination of α-glucosidase activity. In this detection system, the fluorescence of F-PDA was firstly quenched by CoOOH nanosheets based on fluorescence resonance energy transfer (FRET). Subsequently, ascorbic acid was produced from 2-O-α- d -glucopyranosyl- l -ascorbic acid which was selectively hydrolyzed by α-glucosidase. CoOOH was reduced to Co 2+ by the released ascorbic acid, which resulted in the recovery of F-PDA nanoparticles fluorescence. In consequence, α-glucosidase activity was determined by the fluorescence recovery degree of the F-PDA nanoparticle. This fluorescent method showed a good linear relationship with the activity of α-glucosidase from 2 to 80 U L −1 and low detection limit of 1.65 U L −1 (S/N = 3). This fluorescence probe with high selectivity and sensitivity demonstrated a remarkable applicability in human serum samples and provided an alternative for α-glucosidase inhibitors screening in the discovery of anti-diabetes drugs.
研究领域:
生物化学
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医学检测
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纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2022
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IF 14.224
Zhefei Zhao,Li Yu,Lingxia Zheng,Tianyang Guo,Zhuoqing Lv,Shuang Song,Huajun Zheng
The development of catalysts with high atom utilization and activity is the biggest challenge for electrocatalytic hydrodechlorination (EHDC) technology . Herein, a design strategy of TiO 2 @PDA inorganic-organic core-shell skeleton for loading lower dosage of noble palladium (Pd) with robust activity is reported. The self-supported TiO 2 @PDA nanorod arrays provides exposed surface area for anchoring Pd and PDA as interlayer controls the Pd nucleation to form nanodots with high dispersion, realizing high atom utilization. Moreover, the strong interaction between PDA and Pd realizes the coexistence of electron-rich and deficient Pd species with suitable proportion, which facilitate the H* formation and the C-Cl bond activation, respectively, resulting in the promoted activity. The optimal TiO 2 @PDA/Pd electrode exhibits a low dosage of Pd (0.093 mg cm −2 ) and excellent activity for 4-chlorophenol reduction with a mass activity (MA) of 23.96 min −1 g −1 , which is 3.31 times as high as that of TiO 2 /Pd. The design scheme with inorganic-organic core-shell skeleton as support is benefit for developing highly efficient and lower price elctrocatalysts for EHDC.
研究领域:
材料科学
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环境科学
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电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
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IF 5.2
Hankui Sang,Congming Tang,Kai Ma,Xinli Li
The scarcity of fresh water resources necessitates us to develop an efficient technique for sustainable production of clean water from seawater and wastewater. Here, we constructed the 1 T-MoS 2 /PDA (polyaniline) as a photothermal material for purification of seawater and wastewater to produce clean water through interfacial evaporation by virtue of sunlight. 1 T-MoS 2 has a higher evaporation capacity of water than 2 H-MoS 2 , which was selected to prepare 1 T-MoS 2 /PDA composite for photothermal conversion. As expected, 1 T-MoS 2 /PDA composite offers a higher evaporation rate of water than both 1 T-MoS 2 and PDA , which owes to an excellent light absorbance, low light reflectance and good wettability . Under irradiation of 1 sun, the evaporation rate of water over the 1 T-MoS 2 /PDA composite in pure water reached 1.51 kg m −2 h −1 , and the photothermal conversion efficiency reached 92%. Encouragingly, 1 T-MoS 2 /PDA composite can be well used to treat real seawater and various wastewater such as organic dye solution and heavy metal ion solution, in which the evaporation rate of water is close to pure water, and the quality of water is better than the standard of drinking water established by the World Health Organization (WHO). Besides, 1 T-MoS 2 /PDA composite still maintain an excellent evaporation performance after treatment of acidic solution and alkaline solution, indicating an excellent durability. This work provides a feasible solution for producing clean water by solar-driven interfacial evaporation from seawater and wastewater.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
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2025
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IF 7.8
Shanshan Huang,Bolin Li,Gezi Li,Siyuan Zheng,Kanglin Tian,Weimin Xie,Simiao Wu,Jun Wang,Ying Yu,Xiaoman He
There is currently an urgent need to develop technologies for ciprofloxacin (CIP) removal in wastewater owing to its widespread usage in human and animal populations and subsequent transmission into surface water. Aluminum (Al 2 O 3 ) is an excellent carrier, and polydopamine (PDA) is a surface modifier with a high nitrogen content and strong adhesion, and may represent a potential tool for CIP removal in wastewater. However, minimal research has been conducted on using PDA to improve the interactions between carrier and active components and thus improve the ozone utilization efficiency as well as catalytic activity and stability in CIP removal schemes. To address this research gap, study successfully prepared Fe-Mg/PDA@Al 2 O 3 composite materials for the catalytic ozone removal of CIP from water. The influencing factors and degradation mechanisms of the catalytic ozone treatment of ciprofloxacin wastewater and possible antibiotic degradation pathways were proposed. The removal of CIP was mainly carried out through indirect oxidation dominated by hydroxyl radicals (•OH), in addition to catalyst adsorption and direct ozone oxidation, and the oxidative degradation of CIP conformed to a pseudo-first-order reaction kinetic model. Under ideal operating conditions, the CIP degradation efficiency of Fe-Mg/PDA@Al 2 O 3 /O 3 system reached 91.35% after 15 min. The mineralization efficiency of Fe-Mg/PDA@Al 2 O 3 /O 3 system was significantly higher than that of the single-ozone system. After four repeated uses of Fe-Mg/PDA@Al 2 O 3 , the CIP degradation efficiency remained stable, and the metal ion leaching concentration was within the limit, indicating that Fe-Mg/PDA@Al 2 O 3 demonstrated a high catalytic performance and stability.
研究领域:
环境科学
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水处理工程
✓ 已验证
产品关联
DOI
高影响因子
COMPOSITES PART B-ENGINEERING
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2025
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IF 14.2
Jianhang Du,Xiaogang Bao,Jing Wen,Chen Tang,Chenxu Wang,Changgui Shi,Chengqing Yi,Guohua Xu,Dejian Li
Bone defects caused by osteoporosis present a significant clinical challenge. The primary obstacles to osteoporotic bone regeneration are the persistent decline in osteogenic differentiation potential of bone marrow mesenchymal stem cells (BMSCs) and the abnormally high activity of osteoclasts. Emerging research highlights the crucial role of immunomodulation in osteoporosis. Harnessing the immunomodulatory capabilities of bioactive materials to improve the compromised osteoporotic microenvironment may enhance the osteogenic differentiation potential of BMSCs while reducing osteoclast differentiation and resorption. This strategy offers promising avenues for treating osteoporotic bone defects. In this study, we developed an innovative 3D-printed SrCO 3 @PCL/PDA composite scaffold. Through 3D printing, the polycaprolactone (PCL) matrix was customized to achieve biomimetic structural and mechanical design. The introduced strontium carbonate (SrCO 3 ) allows for the responsive release of Sr 2+ ions in the acidic osteoporotic microenvironment, suppressing osteoclast activity and maintaining a regenerative-friendly environment. The polydopamine (PDA) coating enhances the biocompatibility of the scaffold, thereby promoting cell adhesion and proliferation on its surface. Notably, this novel composite scaffold effectively promotes macrophage polarization towards the M2 phenotype rather than the M1 phenotype, exerting an immunomodulatory effect that improves osteoporotic bone regeneration. In vivo experiments further validated our hypothesis. This innovative composite scaffold offers a promising strategy for the comprehensive treatment of osteoporotic bone defects.
研究领域:
生物材料学
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骨科医学
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免疫学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF INORGANIC BIOCHEMISTRY
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2020
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IF 3.212
Chuhan Zhang,Mingming Zhao,Hangjin Zou,Xinming Zhang,Rongtian Sheng,Yang Zhang,Boyu Zhang,Chenye Li,Yanfei Qi
A new composite, AgPW@PDA@Nisin, with shell-core structure was successfully synthesized by a polydopamine (PDA) surfaced conjugated nisin (an antibacterial 34 amino acid polycyclic peptide) as shell and polyoxometalates (Ag 3 PW 12 O 40 = AgPW) as core. The composite was characterized by the zeta potential , scanning electron microscopy (SEM), transmission electron microscope (TEM), X-ray diffraction analysis (XRD), fourier transform infrared (FT-IR). The AgPW@PDA@Nisin showed flower hierarchical structure and potential antibacterial activity against S. aureus ATCC29213. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of it were 4 and 32 μg/mL. AgPW@PDA@Nisin nanoflowers-induced bacterial death bears the characteristic of cell morphology, membrane integrity and permeability changing, nucleotide leakage. It indicated that the AgPW@PDA@Nisin interfere with the cell membrane, resulting in antibacterial activity against S. aureus. The cytotoxicity of the nanoflowers was low on HDF-a (human dermal fibroblasts) cells. A new class of hybrid inorganic-organic nanoflowers based on polyoxometalates and nisin with enhanced antibacterial properties can be developed for food preservation.
研究领域:
微生物学
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材料科学
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食品科学
✓ 已验证
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2024
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IF 4.3
Lun Han,Xu Wang,Bin Yu,Xiaoyuan Qin,Baocheng Liu,Xu Han,Huifen Yuan,Bin Yu,Zhiqi Zhao
Glucose is a key biomarker of diabetes, and effective glucose monitoring methods are crucial to the prevention and management of diabetes. Therefore, in this paper, Fe 3 O 4 /DEX/PDA@Au (Raman reporters) @Au nanocomposites were synthetized that with DTNB (5,5′-dithiobis(2-nitrobenzoic)), MMTA (2-mercapto-4-methyl-5-thiazole acetic acid), MBA (4-mercaptobenzoic acid) and 4-Mpy(4-Mercaptopyridine) were used separately as Raman reporters. Fe 3 O 4 and PDA (Polymerized dopamine) could supply more high surface area of active sites and high SERS (Surface-Enhanced Raman Scattering) substrate, which has high stability and reproducibility. Dextran coating is an effective way to prepare biocompatible materials TEM, XRD, TG and VSM were used to analyze the size, morphology and magnetic properties of the nanocomposites. Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au that integrates a multi-hotspot structure and magnetic separation techniques were studied the enhancement effect of Raman spectra, and glucose solutions with different concentrations were tested. Furthermore, the optimal Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au nanocomposites were supplied as SERS substrates for detection of glucose accurately and quickly in sweat. SERS signal intensity is linearly correlated with glucose concentration within the measurement range of 5 × 10 -3 to 10 mM, and the minimum detectable concentration is 5 µM. The Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au nanocomposites exhibit high reliability, specificity and repeatability of the strategy were then verified by practical detection of sweat.
研究领域:
生物医学工程
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
·
2022
·
IF 3.571
Xueni Zhong,Qianqian Lv,Qiyun Yong,Wenping Hu,Dan Li,Shuhui Ji,Liuyue Zhan,Wenbin Chen,Min Li,Jinsheng Lin,Cuirong Sun
Elagolix sodium (ELS) is a marketed product using to release moderate to severe endometriosis-associated pain. It contains functional groups such as carboxyl group , secondary amino group , 2,4-dioxo pyrimidinyl and several benzyl or benzyl-like position hydrogen atom that are susceptive to occur stress degradation. Forced degradation studies of ELS reveal different degradation profiles of the drug substance which are conducted under photo, thermal, acidic, neutral, alkaline and hydrogen peroxide oxidative conditions in the direction of the ICH guidances. With structural elucidation of LC-PDA/UV-MS n and NMR, the degradants were identified, and seven new degradants are reported in this study. It is confirmed that most of the degradation behaviors of ELS are related to the carboxyl group and secondary amino group in the 3-carboxyl propylamine side chain. Under the oxidative condition using hydrogen peroxide as the oxidant , the secondary amine was oxidized to form an N -hydrogen amine degradant and two further degradants of amine and carbonyl analogs were generated. Under the alkaline degradation condition, the ELS is proven to be stable and no obvious degradants are produced. On the other hand, under the acidic and neutral degradation condition, the 2,4-dioxo pyrimidinyl core of elagolix sodium is stable but the carboxyl group and secondary amine will occur ring cyclization to form the δ -lactam analogs of elagolix sodium. The plausible mechanisms for the degradation of acidic, thermal, photo-degradative and hydrogen peroxide mediated oxidative of elagolix sodium are proposed. It is worth to note that DP-3–4 are the potential degradants which are only found in the solution degradation and are not the real impurities of elagolix sodium.
研究领域:
药物化学
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分析化学
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药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）