JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
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2016
·
IF 4.179
Yuan Wang,Yan-Ling Luo,Feng Xu,Ya-Shao Chen,Wei Tang
Ferrocene-containing amphiphilic block copolymers , poly(2-acryloyloxyethyl ferrocenecarboxylate)- block -poly(2-(dimethylamino) ethyl methacrylate) (PAEFc- b -PDMAEMA), were synthesized via sequential ATRP , and self-assembled into globular nanoscaled micelle aggregates. The copolymer micelles exhibited reversible redox on-off switch feature, which was mediated by using H 2 O 2 , KMnO 4 , NaClO and FeCl 3 as a model of oxidants and ascorbic acid as a model of reductants. The micelle nanoparticles were used to load and deliver anticancer drug, 10-hydroxycamptothecine, finding that the encapsulated drug was rapidly delivered by selectively responding to redox environments in cancer cells. MTT assays were performed to uncover cytotoxicity of the developed copolymer micelles and potentiality used for cancer therapy.
研究领域:
高分子化学
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纳米医学
·
癌症治疗
✓ 已验证
产品关联
DOI
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2014
·
IF 0.872
Jingyun Wang,Fangling Ji,Jishuang Xing,Shuang Cui,Yongming Bao,Wenbo Hao
A block copolymer of 2-dimethylaminoethyl methacrylate (DMAEMA) and glycidyl methacrylate (GMA) was grafted onto the surface of magnetic nanoparticles (Fe 3 O 4 ) via atom transfer radical polymerization . The resultant PGMA-b-PDMAEMA-grafted-Fe 3 O 4 magnetic nanoparticles with amino and epoxy groups were characterized by Fourier transform infrared spectroscopy, powder X-ray diffraction, thermo-gravimetric analysis, and scanning electron microscopy. Lipase from Burkholderia cepacia was successfully immobilized onto the magnetic nanoparticles by physical adsorption and covalent bonding. The immobilization capacity of the magnetic particles is 0.5 mg lipase per mg support, with an activity recovery of up to 43.1% under the optimum immobilization condition. Biochemical characterization shows that the immobilized lipase exhibits improved thermal stability, good tolerance to organic solvents with high lg P , and higher pH stability than the free lipase at pH 9.0. After six consecutive cycles, the residual activity of the immobilized lipase is still over 55% of its initial activity.
研究领域:
生物化学
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材料科学
·
酶工程
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产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2017
·
IF 3.981
Yuanyuan Liu,Qing Liu,Haiyan Yu,Shujun Sun,Yun Xue,Yan Wang,Qishu Qu,Chao Yan
A novel fibrous mesoporous silica nanoparticles ( f SiO 2 ) stationary phase grafted with polymer (Poly (2-(dimethylamino) ethyl methacrylate) (PDMAEMA) was developed for open tubular capillary electrochromatography (OT-CEC). The preparation procedure included synthesizing f SiO 2 through biphase stratification approach, removing the surfactants, silanization and in situ graft polymerization with monomers via atom transfer radical polymerization (ATRP). Subsequently, PDMAEMA-modified mesoporous silica nanoparticles (P- f SiO 2 )/ethanol solution was immobilized onto the inner surface of the pretreated capillary and functionalized with octadecylsilane to fabricate the open-tubular column. Separation of polycyclic aromatic hydrocarbons (PAHs) and proteins were carried out to evaluate the performance of the column in CEC. The run-to-run, day-to-day and column-to-column reproducibility in terms retention time of naphthalene was 1.9%, 2.2%, and 3.7%, respectively. The effects of solvent concentration and pH on the separation were evaluated. The method was also used for the separation of real bio-sample, egg white proteins.
研究领域:
分析化学
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Polymeric Materials and Polymeric Biomaterials
·
2017
·
IF 1.515
Ping Jiang,Jinlong Zhang,Shan Shan Jia,Yiqiang Wu,Qinlin Wu
First, ethyl cellulose-g-poly(2-(dimethylamino) ethyl methacrylate) (EC-g-PDMAEMA) was synthesized through atom transfer radical polymerization. Second, the polymer was used to prepare self-supporting microporous membranes through nonsolvent-induced phase separation process. The chemical structures of EC0.2-g-PDMAEMA15 was confirmed by 1H NMR and FTIR. And the copolymer micelles were characterized by UV, laser particle-size analysis, and TEM. The results indicated that the copolymer had pH- and temperature-responsive behaviors. Furthermore, the morphology study of microporous membranes indicated that the pores became smaller and more uniform with the increase of tetrahydrofuran (THF) content and “open time”, and the most optimal preparation conditions were using 75% THF/25% DMF (v/v) as solvents with the “open time” 30 s. What’s more, the membranes were responsive to pH and temperature stimulus in terms of water flux.
研究领域:
材料科学
·
高分子化学
✓ 已验证
DOI
高影响因子
Gels
·
2026
·Vol. 12
·期 9
·830
·
IF 6.4
Ming Zhong,Yang Xiong
To mitigate clay hydration and wellbore instability during deepwater drilling, a pH/temperature dual-responsive graft copolymer, hyperbranched polyethylenimine-g-poly(2-(dimethylamino)ethyl methacrylate) (HPEI-g-PDMAEMA), was designed and synthesized via free radical polymerization. Optimized synthesis at an HPEI/DMAEMA mass ratio of 1:2 with 2.4% AIBN at 70 °C for 10 h yielded a grafting ratio of 35.2% and a molecular weight of 84.3 kDa. The copolymer exhibits a tunable lower critical solution temperature (LCST) of approximately 48 °C at pH 8, decreasing with increasing pH due to tertiary amine deprotonation. Zeta potential measurements confirm that the polymer retains a positive charge (+5 mV at pH 8) under weakly alkaline conditions, enabling strong electrostatic anchoring onto negatively charged clay surfaces. Above the LCST, dynamic light scattering reveals a sharp increase in hydrodynamic diameter from ~30 nm to >200 nm, confirming a hydrophilic-to-hydrophobic transition of PDMAEMA segments that drives the formation of a hydrophobically associated gel barrier. This thermally triggered gelation is fully reversible, as evidenced by repeated heating–cooling cycles with almost complete transmittance recovery. The gel barrier drastically reduces water uptake, with inhibition performance against clay swelling at 60 °C being 18.5 percentage points higher than that at 25 °C. Hot-rolling tests demonstrate that with only 1.5 wt% inhibitor, shale recovery reaches 94.1% at 150 °C (8.8 percentage points higher than unmodified HPEI) and remains above 60% even in 20 wt% CaCl 2 or MgCl 2 brines, highlighting exceptional resistance to divalent cations. Water contact angle on treated clay surfaces increases from 18.5° to 52.6°, confirming effective surface hydrophobization. This work provides a molecular-level gel-engineering strategy where pH governs electrostatic anchoring and temperature triggers reversible hydrophobic gelation, enabling on-demand switching of clay wettability and hydration resistance under high-temperature, high-salinity conditions.
✓ 已验证
DOI
PubMed
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2022
·
IF 6.206
Tongtong Ding,Luyao Xu,Xiangting Liu,Liang Ma,Yingxin Cui,Dalong Li,Xiuhua Sun,Changlu Gao
To achieve prolonged and sustainable release of copper ion in Cu 2 O-containing marine coatings, poly(lauryl methacrylate)-b-poly(2-( N , N -dimethylamino)ethyl methacrylate) (PLMA-b-PDMAEMA) diblock copolymers with different block ratios and molecular weights were synthesized by atom-transfer radical polymerization (ATRP) method. It was proved that the copolymers are able to coordinate with copper ion. And the surface wettability tests showed that the amphiphilic copolymers may undergo structure change in seawater. Taking advantage of the structure transformation and copper coordination abilities, the copolymer was employed to encapsulate Cu 2 O for the preparation of antifouling coatings. A controllable and continuous release of copper ion from Cu 2 O/copolymer coatings was then obtained. More importantly, it showed that higher PLMA/PDMAEMA block ratio exhibited better bactericidal rate. Actually, the bactericidal ability of the coating depends on the time duration of copper ion on the surface instead of the hydrolysis speed of the coating, in other words, the hydrophobic interaction of PLMA with the resin may play a major role in the antifouling performance of the marine coating. Self-polishing coatings Cu 2 O/copolymer/polycaprolactone (PCL) were then prepared and applied for marine field test, the antifouling performances were proved to be comparable to that of the commercially available self-polishing coatings.
研究领域:
材料科学
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海洋生物学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2023
·
IF 6
Jiayi Wang,Yicen Ge,Yue Wang,Rui Sun,Xiao Yang,Haodan Xue,Xiaoyan Ma,Jinyu Liu,Keling Hu
Pd nanoparticles (NPs) supported by micelles formed with poly(2-(dimethylamino)ethyl methacrylate)- b -poly(lauryl methacrylate) (Pd/PDMAEMA- b -PLMA) were prepared and employed as catalyst in the Suzuki-Miyaura cross-coupling reaction of aryl bromides with arylboronic acids in water. Most reactions proceeded with high efficiency at room temperature with only 0.05 mol% Pd loading in the absence of ligands, which afforded the desired functionalized biaryls in 73–98 % yields after 24 h. After reaction, Pd/PDMAEMA- b -PLMA retained in the aqueous phase was easily separated from the insoluble biaryl product and could be further reused two times without significant loss in catalytic efficiency. Characterization of the catalyst disclosed that sub-2 nm Pd NPs were embedded in the hydrophilic corona of polymeric micelles that served as nanoreactors in water.
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产品关联
DOI
高影响因子
Journal of Biobased Materials and Bioenergy
·
2016
·Vol. 10
·期 4
·284-289
·
IF 0.635
Jiang Ping,Jia Shan Shan,Wang Shuang,Xiao Jun Hua,Liu Wenjie,Wu Yiqiang
The pH- and temperature-responsive chitosan-graft-poly(2-(dimethylamino) ethyl methacrylate) (CS-g-PDMAEMA) were synthesized via atom transfer radical polymerization (ATRP) and evidenced by FTIR spectroscopy. Chitosan macroinitiator (CS-Br) was prepared by phthaloylation of amino
groups of chitosan and acylation of hydroxyl groups of chitosan with 2-bromoisobutyryl bromide. The pH and temperature responses of the copolymer micelles were characterized by particle diameter and particle size analyzers. The film prepared from CS-g-PDMAEMA was used as a coating film
on the surface of the grape. And the film prepared from 1 wt% CS-g-PDMAEMA solution was able to slow the loss of water in grape. The results revealed that the CS-g-PDMAEMA had potential application as active coating materials in the storage of fresh grape.
研究领域:
食品科学
·
高分子化学
✓ 已验证
DOI
高影响因子
COMPOSITES SCIENCE AND TECHNOLOGY
·
2019
·
IF 6.309
Dongdong Yao,Zhilin Zhang,Yaping Zheng,Yudeng Wang,Dechao Wang
In this work, several polyacrylic acid (PAA) nanocomposite hydrogels containing different dimensional silica nanoparticles densely grafted with poly(2-(dimethylamino)ethyl methacrylate) (SiO 2 @PDMAEMA nano-objects) have been fabricated. Firstly, the spherical and sheetlike SiO 2 @PDMAEMA core/shell nano-objects were prepared based on self-assembly of poly(2-(dimethylamino)ethyl methacrylate)- block -poly(3-(triethoxysilyl)propyl methacrylate) (PDMAEMA- b -PTEPM) gelable block copolymers in bulk. Then, two different shaped SiO 2 @PDMAEMA nano-objects were introduced into the PAA hydrogel construction processes to obtain the corresponding PAA composite hydrogel , respectively. The results indicated that core/shell nano-objects were well dispersed in the PAA matrix, and the ionic bonds were formed between –N(CH 3 ) 2 groups in shell of nano-objects and –COOH units in matrix. The compressive strength of composite hydrogels containing 1–3 wt% of sheetlike or spherical nano-objects dramatically increased. For example, when the strain was 65%, it was increased to its maximum by 355.8% and 113.5% compared with that of pure PAA hydrogel (163.92 kPa), respectively. In addition, as induction of hybrid nanofillers , the swelling degree and water absorption behavior of composite hydrogels changed. Especially, the spherical nano-objects-doped composite hydrogel showed a lower swelling degree than others. The synergistic role from the shape of inorganic SiO 2 core and alkaline component of shell was demonstrated to affect mechanical performance in PAA composite hydrogel.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Polymer Chemistry
·
2010
·Vol. 1
·期 10
·1638-1643
·
IF 0
Yin Wang,Guohua Jiang,Xinke Sun,Miaojun Ding,Hongyuan Hu,Wenxing Chen
Shell cross-linked polymeric nanoparticles were prepared through an interfacially confined copolymerization of styrene and disulfide cross-linker in a reversible addition-fragmentation chain transfer (RAFT) miniemulsion system using poly(2-(dimethylamino) ethyl methacrylate) (PDMAEMA) as stabilizer and macroinitiator. 1H NMR, FT-IR, and FE-SEM have been applied to investigate the structures and morphologies of the resultant nanoparticles. Fluorescent spectra results show that the as-prepared samples have fluorescent properties, which may be used as a fluorescent carrier for control release of guest molecules.
研究领域:
高分子化学
·
纳米医学
·
药物递送
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生物材料
·
聚合物科学
✓ 已验证
DOI
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Yilei Fang,Mengyu Tang,Xu Wu,Jiajie Zhang,Qian Guan,Yinzhou Luo,Xin Yu,Ranwen Ou
Trace amount of Cr(VI) in water still threatens human health and ecology. Several reported amine-based adsorbents can remove trace Cr(VI) in acidic solutions of pH 2–5, but perform badly at neutral and alkaline conditions, which is insufficient for treating natural waters. Also, the chemical eluate leads to secondary pollution. Here, the amine-rich thermo-responsive poly(dimethylaminoethyl methacrylate) (pDMAEMA) was selected based on its high pK a value and introduced into MOFs to produce pDMAEMA-DUT-5 for effective removal of trace Cr(VI) from natural waters. The composite with a polymer loading of 23.4 wt% achieved the highest adsorption capacity of 182.2 mg g −1 under an optimized condition, that is, at pH 3 and 25 °C. Besides, this material effectively reduced trace Cr(VI) content in natural waters from 100 to 1 μg L −1 by one filtration in a column. Its high selectivity was verified and further confirmed by the strong adsorption energy of Cr(VI) and −N(CH 3 ) 2 . Furthermore, the composite could be fully regenerated in 45 °C water within 10 min, concentrating Cr(VI) for 270 folds in one adsorption–desorption cycle and maintaining over 99 % performance after five cycles. It demonstrated excellent removal efficiency, high selectivity, and thermal regeneration stability. This work presents a simple strategy to design highly selective and reusable ion adsorbents for effective and sustainable removal or recovery of toxic and precious ions, while its thermal regeneration function largely simplifies further treatments.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
DESALINATION
·
2015
·
IF 3.756
Jun Yin,Jiancheng Zhou
To avoid the agglomeration of nanoparticles (NPs) in hybrid membranes and alleviate the leakage of NPs during the oily wastewater treatment process , poly(2-(dimethylamino)ethylmethacrylate- co -3-dimethyl(methacryloyloxyethyl)ammoniumpropanesulfonate) (PDMAEMA- co -PDMAPS) grafted silica (SiO 2 ) [SiO 2 - g -(PDMAEMA- co -PDMAPS)] NPs were prepared by grafting PDMAEMA brushes onto SiO 2 NPs surface via the surface-initiated activators regenerated by electron transfer atom transfer radical polymerization (Si-ARGET ATRP). Subsequently, the quaternization of the tertiary amine groups in PDMAEMA and 1,3-propanesultone was performed to get [SiO 2 - g -(PDMAEMA- co -PDMAPS)] NPs. Then, the organic–inorganic hybrid polyethersulfone (PES) membranes with different ratios of SiO 2 NPs (m membranes) and SiO 2 - g -(PDMAEMA- co -PDMAPS) NPs (M membranes) were fabricated via the non-solvent induced phase separation (NIPS) process. Transmission electron microscopy (TEM) images demonstrated that the modification of SiO 2 NPs with PDMAEMA- co -PDMAPS was favorable for their homogeneous dispersion in organic solvents. The results of scanning electron microscopy (SEM) images indicated that the surface porosity and mean pore size of hybrid membranes were increased compared to the neat PES membrane. Furthermore, the M membranes exhibited better hydrophilicity , pure water flux and oil flux than neat PES membrane and m membranes. It was found from filtration results that the total fouling (R t ) and irreversible fouling (R ir ) were significantly reduced due to higher hydrophilicity of hybrid membranes. In addition, after oil-in-water emulsion filtration, M membranes exhibited higher water flux recovery ratio (FRR) value than that of m membranes and neat PES membrane.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）