ANALYTICA CHIMICA ACTA
·
2017
·
IF 4.95
Tong Chen,Ling Zhu,Huiyuan Lu,Guangsan Song,Yuanyuan Li,Hongbin Zhou,Ping Li,Wanning Zhu,Hechen Xu,Lijun Shao
The mixed phosphorylated/methacryloyl polysaccharide derivative was prepared and immobilized onto porous silica surface through the radical polymerization . The successful immobilization of polysaccharide on the silica support was confirmed by FT-IR spectra, elemental analysis and transmission electron microscopy (TEM), and so on. The new stationary phase (MCPP-SP) showed both hydrophilic interaction liquid chromatography (HILIC) and per aqueous liquid chromatography (PALC) characteristics. The chromatographic behaviors were evaluated by investigating the effects of water content, column temperature, mobile phase pH and salt concentration, and a typical PALC retention feature of MCPP-SP based column was observed at high percentage of water content. Compared with C18 column, using MCPP-SP column, separation of polar compounds including synthetic pigments and sulfa compounds in the PALC mode was successfully accomplished. The results demonstrated that MCPP-SP column exhibited stronger retention efficiency for various polar compounds. PALC as a green chromatography analytical method was suitable for the replacement of HILIC.
研究领域:
分析化学
·
色谱技术
·
绿色化学
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PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2026
·
IF 7.3
Hang Du,Shuxia Zhang,Dacheng Hao,Sijia Li,Chang Guo,Leyu Wang
Abstract Per- and polyfluoroalkyl substances (PFASs), as a class of persistent organic pollutants, pose a great risk to the ecological environment and human health. The development of rapid and accurate assays for PFASs detection is therefore critically important, yet remains challenging. In this work, we designed a fluorescence sensor system based on single-atom catalysts (SACs) for the detection of PFASs. PFASs could block the atom-specific catalytic sites through hydrophobic–hydrophobic interaction and electrostatic interaction, attenuating the catalytic activity, which leads to the weakening of the colorimetric reaction of 3,3′,5,5′-tetramethylbenzidine (TMB). The resultant colored product (TMBOX) exhibits a substantially reduced fluorescence quenching effect on subsequently added fluorescent carbon dots (CDs). In other words, the bright fluorescence of CDs was well maintained in the presence of a trace amount of PFASs; otherwise, it was significantly quenched in the absence of PFASs. The sensor for PFOA was proposed based on Fe SACs with a detection limit of 1.8 ppb (4.4 nM). Furthermore, when various PFASs interact with a series of SACs, different fluorescence intensity changes could be observed due to the different affinities. Thus, three SACs (Fe, Co, and Cu SACs) were used as the sensing units to construct a fluorescence sensor array. When combined with linear discriminant analysis (LDA) and hierarchical cluster analysis (HCA), qualitative and quantitative detection of six structural PFASs was achieved. This study provides a novel strategy for rapid screening and multidimensional sensing analysis of organic pollutants in real environmental water samples.
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Separation Science Plus
·
2025
·Vol. 8
·期 9
·e70121
·
IF 1.6
Chunmiao Bo,Xuyan Quan,Yan Li,Weilong Zhao,Shengwei Guo
Green separation has garnered escalating attention in recent years. The goal is to develop stationary phases that provide sufficient retention and separation in pure water or high-content water as the mobile phase. Here, vinylcaprolactam (VCl) polymer-modified silica (SiO 2 @poly(VCl)) was prepared through ATRP technique, and then carbon dots (CDs) were further bonded at the end of poly(VCl) chains, fabricating SiO 2 @poly(VCl)-CDs hydrophilic stationary phase. Characterization of SiO 2 @poly(VCl)-CDs demonstrated that poly(VCl) and CDs were successfully decorated onto SiO 2 surface. Since the acrylamide groups in poly(VCl) and charged amino as well as carboxyl groups in CDs, the packed SiO 2 @poly(VCl)-CDs column was employed for per aqueous liquid chromatography (PALC) using nucleic bases, organic acids, and β-agonists as test solutes, resulting in good separation. Most importantly, the baseline separation for those solutes was achieved by using 100% water as the mobile phase. Beyond that, using 100% water of green separation condition, SiO 2 @poly(VCl)-CDs column had the superior ability in separation and determination of cyclic adenosine monophosphate (cAMP) from jujube. Accordingly, our devised SiO 2 @poly(VCl)-CDs stationary phase possesses the excellent separation ability toward polar compounds under pure water, having the property of green chromatography.
研究领域:
分析化学
·
色谱学
·
绿色化学
·
药物分析
·
分子生物学
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DOI
高影响因子
ENVIRONMENTAL RESEARCH
·
2026
·
IF 8.2
Fanke Tong,Ruitong Zhang,Deyan Li,Han Qu,Xiang Li,Qiang Gao,Delin Qi,Shubo Deng,Wei Wang
Per and polyfluoroalkyl substances (PFAS) have been classified as emerging pollutants requiring global control, and the development of highly efficient adsorbents is a key technological challenge hindering the effective treatment of PFAS. In this study, we prepared a novel fluorinated amino covalent organic framework (COF-FS-NH 2 ) via multimonomer hybrid synthesis and post-synthesis modification. The kinetic data of PFAS adsorption on COF-FS-NH 2 were well fitted using the pseudo-second-order model. Using the Langmuir model, the maximum adsorption capacities of COF-FS-NH 2 for perfluorooctanoic acid (PFOA), perfluoro-2,5-dimethyl-3,6-dioxanonanoic acid (HFPO-TA), perfluoro-2,5-dimethyl-3,6-dioxaheptanoic acid (C7 HFPO-TA), and perfluoro(2-methyl-3-oxahexanoic) acid (GenX) were found to be 0.331, 0.289, 0.319, and 0.210 mmol/g, respectively. PFAS adsorption mainly relied on the electrostatic interaction between the amino group of COF-FS-NH 2 and the anionic group of PFAS as well as the van der Waals forces. Compared with the conventional activated carbon and resin materials, COF-FS-NH 2 exhibited high selectivity and adsorption capacity for PFAS, with high removal percentage (> 80%) for the four PFAS at environmental concentration (10 μg/L). This study demonstrates that COF-FS-NH 2 has great potential for the efficient removal of PFAS from water, providing a new material strategy for practical water remediation.
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PubMed
高影响因子
ENVIRONMENTAL RESEARCH
·
2021
·
IF 6.498
Ying Liu,Nan Lin,Cao Dai,Jianliang Xu,Yi Zhang,Mingxing Xu,Fei Wang,Yanjie Li,Da Chen
Per- and polyfluoroalkyl substances (PFASs) are anthropogenic compounds that are widely accumulated in human tissues, and the liver is considered a primary target organ for PFASs exposure. The occurrence and distribution of 21 PFASs in liver tissues with tumors (n = 55) and without tumors (n = 55) are investigated in this study. Eleven perfluorinated carboxylic acids (PFCAs) and five perfluorinated sulfonic acids (PFSAs) were detected at high frequencies (45.5%–100 %), while the detection frequencies of five perfluoroalkyl phosphate (PFPAs) were relatively lower (≤29.1 %). PFSAs and PFCAs accounted for up to 82.5%–92.7 % of the total PFASs. Although it was not found to be statistically significant, the concentrations of the total PFASs were slightly higher in the tumor liver samples (mean 64.3, range 5.70–303 ng/g) than those in the non-tumor liver samples (mean 62.7, range 4.08–240 ng/g).The perfluorooctanoic acid (PFOA), perfluorotridecanoic acid (PFTrDA), and perfluorobutanesulphonate (PFBS) showed significant differences (p < 0.05) between the tumor and non-tumor liver samples, and the different distribution levels of these three PFASs may have been a consequence of oxidative stress . The total concentrations of PFASs in the three age groups were in the decreasing order of middle-aged people (45–60) > old people (>60) > young people (<45). The PFASs in females were generally lower than in males, which may have been related to women's special excretion methods (such as childbirth and breastfeeding). The results should be valuable for further mechanistic studies regarding the toxic effects of PFASs in human livers.
研究领域:
环境科学
·
毒理学
·
医学
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PubMed
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2022
·Vol. 29
·期 56
·85454-85464
·
IF 5.19
Wang Wenfeng,Yuan Shu,Kwon Jung-Hwan
The prevalence of per- and polyfluoroalkyl substances (PFASs) in agricultural soils has raised concerns regarding the health risks associated with the consumption of PFAS-contaminated agricultural products. The present study investigated the uptake and translocation of nine PFASs in lettuce using a hydroponic setting. During the uptake experiments, long-chain PFASs (≥ C8) exhibited greater accumulations in lettuce roots, while short-chain PFASs (≤ C7) manifested preferential transport to the shoots. The average root concentration factors of PFASs were positively correlated with their log K ow values. A significantly negative relationship was found between the average translocation factors of PFASs and their molecular volume. Sorption of long-chain PFASs by lettuce roots was enhanced after heating the roots to increase the cell membrane permeability. The accumulation of perfluorododecanoic acid increased significantly in shoots of lettuce plants without roots as compared to whole lettuce plants. Results of the present study indicate that sorption to root surface tissues and efficiency in passing through the root Casparian strip are two important factors that affect the uptake and distribution of PFASs within plants.
研究领域:
环境科学
·
植物生理学
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Mingkun Zhang,Xianjun Tan,Wenhui Ding,Zhenying Jiang,Kai He,Bo Zhao,Haruka Takeuchi,Yuxiong Huang
The residual fluorion (F – ) generated during per- and polyfluoroalkyl substances (PFASs) treatment presents a new environmental burden, while minimum attention has been redirected to its removal. In this study, Al-based electrocoagulation (EC) technique was optimized to effectively remove the residual F – during PFASs wastewater treatment. At EC’s optimal operating conditions, it can achieve over 81.7 % removal efficiency within 30 min. Furthermore, EC exhibited a stable performance on removing F – across a wide range of pH (3–11), and could form stable flocs under neutral pH conditions. The in-depth characterization of flocs has revealed the dynamic change of Al-F species along the EC process, and removal mechanisms were proved to be a combination of complexation, ion exchange, hydrogen bonding and precipitation. In addition, the optimized EC showed stable removal efficiency of F – with the co-existence of multiple PFASs. Hence, we have effectively removed the residual F – during PFASs wastewater treatment, and provide new insights to better understand the defluorination mechanisms in the EC process.
研究领域:
环境科学
·
水处理工程
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高影响因子
Water
·
2024
·Vol. 16
·期 11
·1513
·
IF 3
Jingqi Huang,Zhen Zhao,Jing Liu,Shiyue Li
Jiangsu High-Tech Fluorochemical Industrial Park in Changshu City, Jiangsu Province, is the largest fluorochemical industrial park in Asia. The occurrence of per- and polyfluoroalkyl substances (PFASs) in surface water and widespread local plants was investigated in Jiangsu High-Tech Fluorochemical Industrial Park. Thirty-two target PFASs were detected in dissolved-phase, particle-phase and plant samples. The concentrations of total PFASs ranged from 1650 to 8250 ng/L in the dissolved-phase samples, 132 to 6810 ng/g dw in the particle-phase samples and 25.8 to 9460 ng/g dw in different plant tissues. Perfluorohexanoic acid (PFHxA), Perfluorooctanoate acid (PFOA) and 6:2 fluorotelomer carboxylic acid (6:2 FTCA) were predominant PFASs and contributed 80−91% to ΣPFAS in water samples. A total of 67 emerging PFAS were identified in all samples using nontargeted analysis.Typha orientalisshowed better accumulation ability, with an average ΣPFAS concentration of 3450 ng/g dw and the highest root concentration factor (RCF) of 171.Typha orientalis,Eichhornia crassipesandAlternanthera sessilishave potential for use in PFAS phytostabilization.
研究领域:
环境科学
·
化学
·
生态学
·
毒理学
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DOI
高影响因子
OPTICS LETTERS
·
2020
·Vol. 45
·期 5
·1047-1050
·
IF 3.714
Guoquan Qian,Wenlong Wang,Guowu Tang,Xianchao Guan,Wei Lin,Qi Qian,Dongdan Chen,Changsheng Yang,Jiantao Liu,Guiyao Zhou,Shanhui Xu,Zhongmin Yang
In this work, Tm:YAG (Tm:${{\rm Y}_3}{{\rm Al}_5}{{\rm O}_{12}}$) ceramic-derived multimaterial fiber was fabricated by using the molten core method, which has a high gain per unit length of 2.7 dB/cm at 1950 nm. To our knowledge, this is the highest gain per unit length at 2 µm band in similar Tm:YAG-derived multimaterial fibers. A distributed Bragg reflector (DBR) fiber laser was built based on a 10-cm-long as-drawn fiber. The achieved 1950 nm laser, which has a maximum output power of $\sim{240}\;{\rm mW}$ and a slope efficiency of 16.5%, was pumped by a self-developed 1610 nm fiber laser. What is more, an all-fiber-integrated passively mode-locked fiber laser based on the 10-cm-long as-drawn fiber was realized. The mode-locked pulses operate at 1950 nm with duration of $\sim{380}\;{\rm ps}$, and the repetition rate is 26.45 MHz. The results described here indicate that the Tm:YAG ceramic-derived multimaterial fiber with high gain per unit length has promising applications in 2 µm all-fiber fiber lasers.
研究领域:
光学工程
·
材料科学
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PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2017
·
IF 6.32
Xiaochun Li,Fan Yang,Jessica X. H. Wong,Hua-Zhong Yu
We demonstrate herein an integrated, smartphone-app-chip (SPAC) system for on-site quantitation of food toxins, as demonstrated with aflatoxin B1 (AFB1), at parts-per-billion (ppb) level in food products. The detection is based on an indirect competitive immunoassay fabricated on a transparent plastic chip with the assistance of a microfluidic channel plate. A 3D-printed optical accessory attached to a smartphone is adapted to align the assay chip and to provide uniform illumination for imaging, with which high-quality images of the assay chip are captured by the smartphone camera and directly processed using a custom-developed Android app. The performance of this smartphone-based detection system was tested using both spiked and moldy corn samples; consistent results with conventional enzyme-linked immunosorbent assay (ELISA) kits were obtained. The achieved detection limit (3 ± 1 ppb, equivalent to μg/kg) and dynamic response range (0.5–250 ppb) meet the requested testing standards set by authorities in China and North America. We envision that the integrated SPAC system promises to be a simple and accurate method of food toxin quantitation, bringing much benefit for rapid on-site screening.
研究领域:
食品安全
·
生物医学工程
·
分析化学
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DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Yang Zhao,Minyu Wang,Weihua Chu
Per- and polyfluoroalkyl substances (PFAS) have been called "forever chemicals" due to their inherent chemical stability. Their potential toxic effects on aquatic animals and health risk assessments have not been fully elucidated. In this study, we investigated the toxic effects of PFASs at environmentally relevant concentrations (200 ng/L) on crucian carp ( Carassius auratus ). The results showed that PFAS reduced the comfort behaviour of crucian carp and was associated with reduced levels of acetylcholinesterase and dopamine in the brain. PFAS exposure also decreased the activities of total superoxide dismutase, catalase and glutathione peroxidase, while increasing the levels of malondialdehyde. PFAS caused over-expression of the pro-inflammatory cytokines TNF-α, IFN-γ and stress-related genes Caspase-3 , HSP-70 in the fish brain. Pathological staining showed that PFAS caused multifocal demyelination and perineural vacuolization in brain, intestinal tissue also showed reduced villus length and focal damage. PFASs altered the composition of the gut microbiota of crucian carp, significantly increasing the abundance of potentially pathogenic bacteria and the potential pathogenicity of the microbiota. It is suggested that PFASs may cause varying degrees of tissue damage by destabilising the gut microbiota. These results provide insights for assessing the toxicity of PFAS contaminants at aquatic environmental concentrations.
研究领域:
环境毒理学
·
水生生物学
·
微生物学
·
神经科学
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DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2026
·
IF 8.2
Lidong Feng,Tianxiao Leng,Haoyu Sun,Long-Fei Ren,Jiahui Shao
Both phosphate and per- and polyfluoroalkyl substance (PFAS) contaminants pose significant threats to aquatic ecosystems, demanding urgent remediation strategies. Herein, this study proposed a sustainable approach that utilized droplet-microfluidics-assisted chemical cross-linking to graft waste PFAS onto monodisperse microspheres, converting it into a stable, high-performance, and eco-friendly phosphate adsorbent (PFAS-FMM). Importantly, the scalable droplet-microfluidic technology enabled precise control over microsphere dimensions (100–150 μm) and tailored core/shell architecture for effective cross-linker encapsulation. Meanwhile, unlike conventional cross-linking, the single-site grafting enabled by shell microcracks effectively avoided active-site masking and maximized amino group utilization by 4.29-fold, as evidenced by typical polyethylenimine (PEI)-based adsorbents. This structural advantage strengthened the electrostatic attraction and hydrogen bonding of the PFAS-FMM for phosphate adsorption. As a result, the optimized PFAS-FMM exhibited exceptional phosphate (50 mg P/L) adsorption capacity (Qmax of 252.5 mg/g PFAS) and satisfactory kinetics (equilibrium within 120 min). Meanwhile, it demonstrated tolerance to multiple competing anions and maintained an adsorption capacity of over 85% across five cycles. Crucially, microsphere encapsulation eliminated free PFAS leaching, avoiding risks of secondary environmental pollution and ecotoxicity. The application potential was also confirmed by the positive result of the overall sustainability footprint (OSF) (score of 87.5%). These findings provided inspiration for the synthesis of functional materials and presented a strategy for concurrent mitigation of dual aquatic pollutants via waste valorization.
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高影响因子
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