ACS Applied Nano Materials
·
2021
·
IF 5.097
Yiman Zhang,Shiying Fan,Xinyong Li,Liang Wang,Zhifan Yin,Penglei Wang,Moses O. Tadé,Shaomin Liu
The application of carbon-based materials as electrocatalysts for electrochemical dechlorination of chlorinated volatile organic compounds (Cl-VOCs) has stirring extensive concern. However, the relationship between morphology and activity toward carbon-based materials is often overlooked by researchers. Herein, a unique three-dimensional (3D) sea-urchin-like carbon nanosphere containing a hollow interior self-assembled from 1D carbon nanorods (SS-CNRs) has been successfully fabricated. It can be achieved through morphology-preserved thermal conversion of a 3D metal–organic framework (MOF) superstructure, which possesses an identical sea-urchin-like nanostructure consisting of 1D MOF nanorods (SS-MOFNRs). The as-prepared SS-CNRs can be utilized as an efficient cathode catalyst for electrocatalytic dechlorination of 1,2-dichloroethane (1,2-DCA) to selectively produce highly valuable ethylene. Benefiting from the peculiar sea-urchin-like morphology and the void-confinement effect induced by the hollow structure, the SS-CNRs are endowed with an abundant electrode–electrolyte contact area to accelerate the electron transfer. As a result, the as-synthesized catalyst exhibits outstanding electrocatalytic dechlorination performance of 1,2-DCA with high ethylene yield, selectivity, reusability, and stability, where the Faradaic efficiency of ethylene is up to 55% at −2.75 V (vs SCE). This work provides a promising prospect for the rational morphological engineering of carbon-based nanometer materials and the effective transformation of Cl-VOCs to value-added ethylene in a friendlier manner.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Marine Drugs
·
2019
·Vol. 17
·期 8
·438
·
IF 3.772
Xiaoyang Liu,Zixu Wang,Fawen Yin,Yuxin Liu,Ningbo Qin,Yoshimasa Nakamura,Fereidoon Shahidi,Chenxu Yu,Dayong Zhou,Beiwei Zhu
In this study, three synthetic zinc-chelating peptides (ZCPs) derived from sea cucumber hydrolysates with limited or none of the common metal-chelating amino-acid residues were analyzed by flame atomic absorption spectroscopy, circular dichroism spectroscopy, size exclusion chromatography, zeta-potential, Fourier transform infrared spectroscopy, Raman spectroscopy and nuclear magnetic resonance spectroscopy. The amount of zinc bound to the ZCPs reached maximum values with ZCP:zinc at 1:1, and it was not further increased by additional zinc presence. The secondary structures of ZCPs were slightly altered, whereas no formation of multimers was observed. Furthermore, zinc increased the zeta-potential value by neutralizing the negatively charged residues. Only free carboxyl in C-terminus of ZCPs was identified as the primary binding site of zinc. These results provide the theoretical foundation to understand the mechanism of zinc chelation by peptides.Keywords:zinc-chelating peptide;sea cucumber;chelation mechanism
研究领域:
生物化学
·
营养学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CATALYSIS LETTERS
·
2022
·Vol. 153
·期 7
·1974-1987
·
IF 2.936
Dong Fengying,Lin Lin,Su Yue,Zhang Chuan,Wei Wei
Mostly, enzyme activity is greatly reduced after immobilization due to unfavourable conformational change occurred during the immobilization procedure. Herein, we report a novel magnetic nanoparticle-based platform for Bacillus altitudinis esterase (EstBASΔSP) immobilization using dialdehyde starch (DAS) as a molecular glue. First polydopamine (PDA) was coated on the surface of Fe 3 O 4 nanoparticles (Fe 3 O 4 NPs) with a controllable thickness. Thereafter, PDA-functionalized Fe 3 O 4 NPs were modified with dialdehyde starch (DAS) to provide the aldehyde groups, which was employed as a glue to further fix the EstBASΔSP on particle surface via covalent bonding, resulting in the formation of a sea-urchin-like esterase-immobilized magnetic nanoparticle. The obtained nanoparticles (Fe 3 O 4 @PDA/DAS) achieved an enzyme load of 162.72 mg/g and retained 65.7% of its specific enzyme activity, demonstrating better thermal and storage stability compared with the “polydopamine-coated” nanoparticles (Fe 3 O 4 @PDA) and free EstBASΔSP. In addition, in a chloramphenicol palmitate synthesis, the immobilized esterase (EstBASΔSP-Fe 3 O 4 @PDA/DAS) gave 99% conversion and purity in 21 h (chloramphenicol: 0.15 M, enzyme dosage: 50 mg/mL) and retained over 80% of its activity after 12 cycles. This study provides a general strategy for immobilizing enzyme on nanoparticles and employs them as a novel platform for enzyme-mediated biocatalytic reaction. Graphical Abstract
研究领域:
生物化学
·
纳米生物学
·
酶工程
✓ 已验证
产品关联
DOI
高影响因子
Polymers
·
2023
·Vol. 15
·期 9
·2071
·
IF 5
Bing Song,Yang Cao,Liang Wang,Yake Shen,Xiaoming Qian
Ultra-fine fibers derived from sea-island fibers have attracted great attention due to their excellent overall performance. However, green and efficient splitting of sea-island fibers is still a challenging task. In this work, thermoplastic polyvinyl alcohol (TPVA) was prepared by the physical blending of plasticizer. The modified TPVA showed a high decomposition temperature (285 °C) and a wide thermoplastic processing window. This made TPVA match well with polyamide 6 (PA6) to form conjugated melts at 250 °C. Corresponding PVA/PA6 sea-island fibers were first reported to realize water-splitting instead of alkali-extraction of “sea” polymers. The effects of sea/island mass ratios and different spinning speeds on the properties of PVA/PA6 sea-island pre-oriented yarn (POY) were investigated. A higher spinning speed enhanced the orientation-induced crystalline behavior of fiber, therefore increasing the tensile strength of fibers. As the increase of spinning speed from 1000 to 1500 m/min, the crystalline degree of corresponding POYs increased from 9.9 to 14.3%. The plasticizer in PVA did not diffuse to the PA matrix during spinning. However, PVA could induce the crystallization of PA6 via interfacial hydrogen bonding. When the spinning speed was 1500 m/min, and PVA/PA6 was 7:3, the tensile strength reached the highest value of 1.67 cN/dtex. The uniform diameters of ultra-fine PA6 fibers (2–5 μm) were obtained by an environment-friendly water-splitting process. The “sea” phase (TPVA) in sea-island fiber could be removed quickly by boiling water treatment in 3 min. This green and energy-saving sea-island fiber splitting technique is of great significance in reducing CO2emissions during the preparation of super-fine fibers.Keywords:sea-island fiber;conjugated melt spinning;water-splitting;ultra-fine fiber;thermoplastic polyvinyl alcohol
研究领域:
材料科学
·
纺织工程
✓ 已验证
DOI
PubMed
高影响因子
Marine Drugs
·
2021
·Vol. 19
·期 4
·192
·
IF 5.118
Pengrui Wang,Jiapeng Chen,Lujing Chen,Li Shi,Hongbing Liu
Plant volatile organic compounds (VOCs) represent a relatively wide class of secondary metabolites. The VOC profiles of seven seaweeds (Grateloupia filicina,Polysiphonia senticulosa,Callithamnion corymbosum,Sargassum thunbergii,Dictyota dichotoma,Enteromorpha proliferaandUlva lactuca) from the Yellow Sea of China were investigated using multifiber headspace solid phase microextraction coupled with gas chromatography–mass spectrometry (HS-SPME/GC–MS), among them, the VOCs of three red algae Grateloupia filicina, Polysiphonia senticulosa, and Callithamnion corymbosum were first reported. Principal component analysis (PCA) was used to disclose characteristic categories and molecules of VOCs and network pharmacology was performed to predict potential biomedical utilization of candidate seaweeds. Aldehyde was found to be the most abundant VOC category in the present study and (E)-β-ionone was the only compound found to exist in all seven seaweeds. The chemical diversity of aldehydes inE. proliferasuggest its potential application in chemotaxonomy and hinted that divinylbenzene/carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fiber is more suitable for aldehyde extraction. VOCs inD. dichotomawere characterized as sesquiterpenes and diterpenes and the most relevant pharmacological pathway was the neuroactive ligand–receptor interaction pathway, which suggests thatD. dichotomamay have certain preventive and therapeutic values in cancer, especially in lung cancer, in addition to neuropsychiatric diseases.Keywords:volatile organic compounds;seaweeds;characteristic VOCs;chemotaxonomy;biomedical utilization;headspace solid phase microextraction
研究领域:
植物化学
·
药理学
·
海洋生物学
✓ 已验证
DOI
PubMed
高影响因子
Surfaces and Interfaces
·
2026
·
IF 6.3
Yaqi Liu,Yun Ju,Hong Zhang,Jing He,Jie Jiang,Jing Zhao,Mingyi Wang
Sea spray aerosol (SSA) contains abundant anions, which significantly impact CO 2 fixation at the air-water interface in atmospheric microdroplets. However, the underlying molecular mechanism remains unclear. Herein, we simulated SSA using nebulized saltwater microdroplets and investigated the common SSA anions (Cl − , Br − , I − , and SO 4 2− ) intervening in the abiotic carboxylation of succinate with CO 2 at the interface. The combination of online and offline analyses revealed that the SSA anions inhibited the interfacial carboxylation of succinate, with an inhibitory effect inversely proportional to their concentration. Kinetic studies confirmed that the carboxylation reaction occurred at a relatively high rate in the presence of the SSA anions. Furthermore, a mechanistic investigation was performed, which showed that SSA anions inhibited the interfacial carboxylation of succinate by modulating the interfacial electric field. Additionally, the formation of adducts between halogen anions from SSA and succinate suggests a potential pathway for the accumulation of succinate in the early marine environment. This work advances our understanding of air-water interfacial chemistry and provides new insights into prebiotic chemistry in the marine atmosphere.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 13.2
Kai Zheng,Ce Bian,Hetao Chu
Flexible ionotronic sensors hold great promise for tactile electronics owing to their high sensitivity and mechanical compliance. However, conventional ionic conductors suffer from hysteresis and instability, which severely limit their ability to detect high-frequency vibrations. Here, we propose an ionoelastomer that possesses low hysteresis by introducing reversible sea-island structure. The structure, constructed from entropy-elastic segments of acylated poly(ethylene glycol)-b-poly(propylene glycol)-b-poly(ethylene glycol) (PF127-DA), can rapidly respond to external mechanical vibrations, enabling high-frequency sensing. The ionoelastomer-based sensor with dual-microcone structure achieves a maximum sensitivity of 590.2 kPa −1 and a rapid response/recovery time of 0.5/0.5 ms, allowing it to detect vibrations up to 1 kHz. Additionally, the sensor has been applied to audio recognition and an integrated sensor array, demonstrating reliable signal responses in interactive electronics and showing great potential for future interactive and force monitoring applications.
✓ 已验证
产品关联
DOI
高影响因子
Food Bioscience
·
2026
·
IF 6.2
Haoduo Yang,Yiheng Wu,Yu Zhang,Bo Li,Yong-Jiang Xu
Sea buckthorn polyphenols (SBPs) have been reported to alleviate insulin resistance (IR), but their key bioactive compounds and underlying mechanisms remain unclear. In this study, 48 phenolics were annotated from four sea buckthorn varieties. SBPs improved glucose consumption and glycogen synthesis in IR-HepG2 cells, with MON showing the most pronounced effect. Correlation analysis suggested positive associations between several phenolics, including isorhamnetin, kaempferol, quercetin, eriodictyol, and catechin, and cellular glucose metabolism-related indicators. Network pharmacology identified these compounds as representative candidates associated with IR-related targets, including JNK, IRS-1, PI3K, and AKT. Molecular docking further suggested favorable predicted binding affinities between candidate phenolics and selected targets, with isorhamnetin showing relatively strong predicted affinity and cellular activity. Therefore, isorhamnetin was selected as a representative key candidate for mechanistic validation. Mechanistically, isorhamnetin reduced inflammatory and oxidative stress responses, modulated the JNK/IRS-1/PI3K/AKT signaling pathway, promoted glycogen synthesis, suppressed gluconeogenesis, and improved glucose utilization in IR-HepG2 cells. These findings provide preliminary in vitro evidence that isorhamnetin-rich SBPs may serve as promising dietary candidates for improving IR-related glucose metabolic dysfunction.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Tong Wu,Song Ren,Wasim Akram,Tingshan Li,Xiangyu Zhu,Xinran Li,Li Niu,Haojun Fan,Zhe Sun,Jian Fang
A three-dimensional (3D) hierarchical microfiber bundle-based scaffold integrated with silver nanowires (AgNWs) and porous polyurethane (PU) was designed for the Joule heater via a facile dip-coating method. The interconnected micrometer-sized voids and unique hierarchical structure benefit uniform AgNWs anchored and the formation of a high-efficiency 3D conductive network. As expected, this composite exhibits a superior electrical conductivity of 1586.4 S/m and the best electrothermal conversion performance of 118.6 °C at 2.0 V compared to reported wearable Joule heaters to date. Moreover, the durable microfiber bundle–PU network provides strong mechanical properties, allowing for the stable and durable electrothermal performance of such a composite to resist twisting, bending, abrasion, and washing. Application studies show that this kind of Joule heater is suitable for a wide range of applications, such as seat heating, a heating jacket, personal thermal management, etc.
研究领域:
材料科学
·
能源技术
·
纺织工程
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2022
·Vol. 105
·期 6
·3797-3808
·
IF 4.186
Peiping Zhang,Xue Sun,Jiankang Guo,Yan Wang,Wei Zhang,Weikun Ning,Wenqing Li,Cundi Wei,Xuefa Shi,Shiding Miao
Raw deep-sea clays (i.e., pelagic clays) collected from the Indian Ocean were able to function as Fenton catalysts and self-propelled micromotors due to the high content of Fe- and Mn-. The pelagic clays were for the first time observed to be automatic in the H 2 O 2 solution. The pelagic clays existed in the form of poorly crystallized marine sedimentation. The major minerals were found as illite/montmorillonite (I/M) and amorphous ferromanganese nodules, and the minor minerals included kaolinite, quartz, feldspar, and calcite. Significant amounts of oxygen bubbles were generated when the clay particles were dispersed into the H 2 O 2 solution (0.1–10.0 wt.%), and the average velocity of the motors was observed as high as 183.0 μm s –1 in 10.0 wt.% H 2 O 2 . The self-propulsion would induce vigorous mixing in local areas of the solution and was confirmed to benefit the catalytic performance. The clays were employed to remove Rhodamine B (RhB) for a proof-of-concept study. In the acid solution (pH = 1.0–5.0), the removal of RhB was controlled by the Fenton process accompanied by the adsorption of clay particles. In the alkaline solution (pH = 9.0), the removal of RhB was found to follow an adsorptive bubble separation pathway. Both processes were greatly influenced by the self-motion of MnO x motors contained in the pelagic clays.
研究领域:
环境科学
·
材料科学
·
催化化学
✓ 已验证
DOI
高影响因子
AQUACULTURE RESEARCH
·
2016
·Vol. 48
·期 5
·2278-2290
·
IF 1.606
Jing Qian,Chunhua Ren,Ting Chen,Jianjun Xia,Zonghe Yu,Yan Gao,Chaoqun Hu
The broad-spectrum protease inhibitor alpha-2-macroglobulin (α 2 M) is widely found in vertebrates and invertebrates. However, no research regarding α 2 M has been described in sea cucumbers to date. In this study, the first sea cucumber α 2 M named Stm α 2 M was identified from Stichopus monotuberculatus , a tropical species with high edible and economic values in Southern China. The Stm α 2 M cDNA is 5276 bp in length, containing a 5′-untranslated region (UTR) of 279 bp, a 3′-UTR of 344 bp and an open reading frame of 4653 bp that encodes a protein of 1550 amino acids. The Stmα 2 M possesses all the three characteristics of known α 2 M proteins, including the bait region domain, thioester domain and receptor-binding domain. Higher levels of mRNA expression were noticed in intestine, respiratory tree, coelomocytes and tentacle of S. monotuberculatus . Transcriptional expression of Stm α 2 M showed the strongest response to lipopolysaccharides (LPS, 8.19-fold up-regulation) after 6 h post-challenge in coelomocytes. In addition, the α 2 M activity was detected in S. monotuberculatus and protein activity of α 2 M increased remarkably at 6 h after LPS stimulation. As a whole, this study indicated that Stmα 2 M is an important immune-related molecule, and the study on functions of Stmα 2 M may provide some new and valuable ideas for preventing and controlling diseases of cultured sea cucumbers.
研究领域:
免疫学
·
分子生物学
·
海洋生物学
✓ 已验证
产品关联
DOI
高影响因子
FITOTERAPIA
·
2023
·
IF 3.4
Yang Liu,Limei Ran,Yahong Wang,Peng Wan,Hongli Zhou
The polysaccharides from Sea buckthorn leaves (SBLPs) were extracted by hot water and purified by DEAE cellulose , then separated into six polysaccharides (SBLP-S) by DEAE-52 column. Six separated polysaccharides were characterized by Ultraviolet Spectroscopy, Infrared Spectrum, High Performance Liquid Chromatographic and Congo red analysis. The antioxidant activity and immunological activity were investigated in vitro . The results revealed that the monosaccharide composition of SBLP-S-1, SBLP-S-2, SBLP-S-3, SBLP-S-5 and SBLP-S-6 contained Man , GlcN , Rib , Rha , GluA , GalA , Glu, Gal, Xyl , Ara and Fuc , among them, rare glucosamine was found. And SBLP-S-4 contained all above components except GlcN and GluA. FT-IR showed that SBLP-S were sulfated polysaccharide containing uronic acid . Molecular weights of SBLP-S were 338.659, 401.305, 599.849, 393.904, 626.895 and 176.862 kDa. The Congo-red test indicated that SBLP-S-2, SBLP-S-4, SBLP-S-5, and SBLP-S-6 had triple helix conformation. Crude polysaccharides had the strong scavenging activities on DPPH radicals, ABTS radicals and hydroxyl radicals . The six polysaccharides had the activity of immune stimulation on RAW264.7 cell. SBLP-S-2 promoted the phagocytosis best and SBLP-S-6 promoted the NO production best. The results suggested that SBLPs could be used as potential antioxidants and immunomodulatory agents in pharmaceutical and functional food fields.
研究领域:
药理学
·
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）