PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
·
2022
·
IF 7.926
Hailin Yu,Huili Zhang,Xin Wei,Yong Chen,Bo Yu,Yingjun Wang,Hongsheng Liu
Efficient purification of oily sewage, recycling, and standard discharge have become key issues for the sustainable development of oil fields. In this study, the surface of PPFS was organically modified by a silane coupling agent . Then, covalently bonded cationic block inorganic-organic composite coagulant was prepared by chosen sodium polyacrylate as the template. This unique structure significantly enhances the positive charge and molecular chain length of the coagulant, thus improving its ability to perform charge neutralisation, adsorption bridging, and sweep coagulation. The characteristic functional groups and thermophysical properties of the composite coagulant were analysed by FTIR and thermogravimetric analysis . The transformation of random copolymers to block copolymers was determined by 1 H NMR, thus confirming the successful synthesis of the cationic block structures. The turbidity removal and oil removal properties of oily sewage were investigated by coagulation experiment. The Zeta potential , dynamic and static light scattering, and field emission scanning electron microscopy (SEM) were used to study the effect of composite coagulants on the microscopic morphology and coagulation of flocs. Finally, the coagulation mechanism of the compound coagulant was analyzed with the dynamic change of the particle size of the flocs. The cationic block structure in TP(AM-DAC-PPFS) can effectively neutralise the negative charges on the surface of impurity particles and emulsified oil. The optimal dosage of TP(AM-DAC-PPFS) was 30 mg·L −1 , at which the turbidity and oil removal rates can reach 98.3% and 93.8%, respectively.
研究领域:
环境工程
·
水处理
·
高分子科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Jiajia Liu,Juntao Wang,Yaxing Guo,Xiumin Yang,Qiuhua Wu,Zhi Wang
In this work, a porous extended network covalent organic framework designated as TP-NDA-COF was synthesized by the reaction of 2,4,6-trihydroxy-benzene-1,3,5-tricarbaldehyde (TP) and 1,5-naphthalenediamine (NDA). The structure and morphology of the TP-NDA-COF was characterized by means of Fourier transform infrared spectra (FT-IR), thermal gravimetric analysis (TGA), X-ray diffraction (XRD) and scanning electron microscope (SEM). The TP-NDA-COF was applied as a solid-phase extraction adsorbent for the extraction of some chlorophenols from water and lemon black tea beverage samples prior to high performance liquid chromatography-UV detection. The main experimental parameters that affect the extraction efficiency including the type and volume of eluent, sample solution volume, sample loading rate and sample solution pH were investigated. Under the optimal conditions, the calibration curves were linear in the range of 0.30–60.0 ng mL −1 with the determination coefficients ( R 2 ) of 0.9996–0.9998 for water samples and in the range of 0.60–60.0 ng mL −1 with the R 2 values from 0.9990 to 0.9996 for beverage samples. At the signal to noise ratio of 3 (S/ N = 3), the method LODs for the analytes were 0.10–0.15 ng mL −1 for water samples and 0.20–0.50 ng mL −1 for lemon black tea beverage, respectively. Good repeatability was achieved with the relative standard deviations of less than 7%. The results showed that the SPE-HPLC method can be used for the determination of chlorophenols in environmental water and foodstuffs samples.
研究领域:
环境科学
·
分析化学
·
材料科学
✓ 已验证
DOI
高影响因子
DESALINATION
·
2025
·
IF 9.8
Fengrui Yang,Xinyu Ma,Jun Wei,Xuanhua Chen,Zhi Wang
The efficient extraction of lithium from salt-lake brine still faces challenges due to the insufficient performance of nanofiltration (NF) membranes. In this study, a nanofiltration membrane was fabricated by first pre-crosslinking polyethyleneimine (PEI) with 1,3,5-triformylphloroglucinol (Tp), followed by interfacial polymerization (IP) with trimesoyl chloride (TMC). The pre-crosslinking step incurred no amine loss. However, the higher molecular weight and increased steric hindrance of the product reduced its subsequent crosslinking with TMC. An optimal balance enables the simultaneous enhancement of both the overall crosslinking density, which is contributed by both pre-crosslinking and TMC crosslinking, and the positive charge density of the membrane. The optimized membrane (Tp 0.12) achieved a pure water permeability of 8.57 L·m −2 ·h −1 ·bar −1 and an ideal LiCl/MgCl₂ selectivity of 32.9, representing 179 % and 700 % of the values for the pristine membrane, respectively. Moreover, the optimal membrane remained effective even when the Mg 2+ /Li + ratio in the feed was as high as 140 or the total salt concentration reached up to 10,000 ppm. This work provides a simple and efficient new pathway for preparing high-performance selective nanofiltration membranes for lithium extraction.
研究领域:
材料科学
·
膜技术
·
分离科学
·
环境工程
·
锂资源回收
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2019
·Vol. 15
·期 50
·1905080
·
IF 10.856
Xiaojing He,Bo Situ,Meng Gao,Shujuan Guan,Bairong He,Xiaoxue Ge,Shiwu Li,Maliang Tao,Hang Zou,Ben Zhong Tang,Lei Zheng
Two-photon photodynamic therapy (TP-PDT) is emerging as a powerful strategy for stereotactic targeting of diseased areas, but ideal photosensitizers (PSs) are currently lacking. This work reports a smart PS with aggregation-induced emission (AIE) feature, namely DPASP, for TP-PDT with excellent performances. DPASP exhibits high affinity to mitochondria, superior photostability, large two-photon absorption cross section as well as efficient reactive oxygen species generation, enabling it to achieve photosensitization both in vitro and in vivo under two-photon excitation. Moreover, its capability of stereotactic ablation of targeted cells with high-precision is also successfully demonstrated. All these merits make DPASP a promising TP-PDT candidate for accurate ablation of abnormal tissues with minimal damages to surrounding areas in the treatment of various diseases.
研究领域:
诊疗学
·
生物医学工程
·
分子影像
·
癌症治疗
✓ 已验证
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Ningfan Song,Zihan Chen,Jinghua Shi,Dezhi Shi,Li Gu
In the present study, a Pd/Cu bimetallic catalyst supported on a chelating resin (TP207) was prepared in order to selectively reduce nitrate to N 2 with ZVI (zero valent iron) as a reductant. The effects of Pd/Cu mass ratio, temperature, and initial solution pH on the removal of nitrate and TN were then examined. The highest nitrate (63.2%) removal was obtained under neutral conditions at a ratio of Pd/Cu 2:1, in which 57.8% of TN was removed and N 2 accounted for more than 90% of the final products. Additional ammonia (30–40%) were formed when the reaction was conducted at a higher temperature (313 K) compared to when performed at 303 K. The mechanism study for nitrate reduction indicated that this catalyst could broaden the suitable pH range and improve the selectivity of N 2 without the generation of other intermediate compounds or by-products in comparison to ZVI and its combination with a non-supported Pd/Cu catalyst. The slow rate of ZVI corrosion, high Fe(Ⅱ) proportion in corrosion products and high N/H ratio at neutral pH conditions may serve as reasons for the high N 2 selectivity. The chelating resin also played a key role via its load capacity and dispersion ability to Pd/Cu particles in enhancing N 2 selectivity. Accordingly, the proposed method may have great potential application for nitrate reduction to N 2 , which warrants further study.
研究领域:
环境科学
·
催化化学
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-18
·
IF 14.7
Weng Haobo,Zou Weijuan,Tian Fangyan,Xie Huilin,Liu Ao,Liu Wen,Liu Yu,Zhou Nianwei,Cai Xiaojun,Wu Jianrong,Zheng Yuanyi,Shu Xianhong
Heart failure causes considerable morbidity and mortality worldwide. Clinically applied drugs for the treatment of heart failure are still severely limited by poor delivery efficiency to the heart and off-target consumption. Inspired by the high heart delivery efficiency of inhaled drugs, we present an inhalable cardiac-targeting peptide (CTP)-modified calcium phosphate (CaP) nanoparticle for the delivery of TP-10, a selective inhibitor of PDE10A. The CTP modification significantly promotes cardiomyocyte and fibroblast targeting during the pathological state of heart failure in male mice. TP-10 is subsequently released from TP-10@CaP-CTP and effectively attenuates cardiac remodelling and improved cardiac function. In view of these results, a low dosage (2.5 mg/kg/2 days) of inhaled medication exerted good therapeutic effects without causing severe lung injury after long-term treatment. In addition, the mechanism underlying the amelioration of heart failure is investigated, and the results reveal that the therapeutic effects of this system on cardiomyocytes and cardiac fibroblasts are mainly mediated through the cAMP/AMPK and cGMP/PKG signalling pathways. By demonstrating the targeting capacity of CTP and verifying the biosafety of inhalable CaP nanoparticles in the lung, this work provides a perspective for exploring myocardium-targeted therapy and presents a promising clinical strategy for the long-term management of heart failure.
研究领域:
心脏病学
·
纳米医学
·
药理学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Small
·
2024
·
IF 13
Lili Xu,Jianli Nan,Songxue Han,Zhixuan Yu,Shuangli Wu,Youxing Fang,Shaojun Dong
In nature, active Mn 3+ –ligand complexes produced by laccase catalyzed oxidation can act as the low-molecular mass, diffusible redox mediators to oxidize the phenolic substrates overcoming the limitations of natural enzymes. Learning from the metal–ligand coordination of natural functional units, high-valence Mn metal–organic framework (Mn MOF) is constructed to simulate the catalysis in natural mediator system. Benefiting from the characteristics of nanoscale size, rich metal coordination unsaturated sites, and mixed valence state dominated by Mn(III), Nano Mn(III)-TP exhibits superior laccase-mimicking activity, whose V max (maximal reaction rate) is much higher than that of natural laccase. Referring to natural systems, relevant free radical experiments prove that the material induces the production of active oxygen species with the assistance of carboxylic acid, and active oxygen species further oxidize phenolic substrates. Based on its robust performances, the primary oxidative degradation of an emerging pollutant triclosan (TCS) is creatively applied, an important antiasthmatic medicine terbutaline sulfate (TBT) detection, and the synthesis of non-toxic and black near-natural dyes for dyeing. By simulating the essential mediators of natural enzymatic catalysis, an Mn MOF-based material that demonstrates multiple novel applications is successfully developed, which introduces a new reliable strategy for achieving versatile nature-mimicking catalysis.
研究领域:
催化
·
材料科学
·
环境化学
·
分析化学
·
有机合成
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Xiaona Dong,Ruonan Feng,Xiaoxue Yang,Yuanming Jiang,Lulu Chen,Liwei Chen,Canlan Jiang,Tianming Cai
Peroxydisulfate-based in-situ chemical oxidation (PDS-ISCO) is a promising technology for soil remediation. The weak potential of soil constituents for PDS decomposition results in the low degradation efficiency of soil contaminants. Herein, we propose a new soil remediation strategy by accelerating the activation efficiency of PDS using chelating and reducing reagents (CRs) to complex and reduce soil Fe-minerals. Experimental results demonstrated that the introduction of tea polyphenols (TP) into soil-PDS system could effectively improve the reduction of Fe-minerals and the degradation of triphenyl phosphate (TPHP) in soil. With increasing TP concentration from 0 to 40 mM, the degradation efficiency of TPHP increased from 10.8% to 58.6% in an upland soil (T1 soil). TP could directly complex and reduce the solid-phase Fe-minerals, leading to a significant increase of Fe(II) content, especially the insoluble Fe(II) content, which could further induce the PDS activation. Results of radical quenching experiments, electron paramagnetic resonance (EPR) analysis, and kinetic solvent isotope effect (KSIE) evaluation showed that sulfate radicals (SO 4 •− , especially surface-bound SO 4 •− ), hydroxyl radicals (HO•, especially surface-bound HO•), and singlet oxygen ( 1 O 2 ) played major roles in TPHP degradation, with the estimated contributions of 39.03%, 43.99%, and 16.98%, respectively. The higher content of high active Fe fractions, such as amorphous Fe, the larger yields of Fe(II) species and TPHP degradation. Increased content of soil organic matter (SOM) and pH value from 2.5 to 8.0 may reduce TPHP degradation. The effects of inorganic anions and Mn-minerals, presented in natural soil, on TPHP degradation were very limited. Simulated in-situ soil remediation using soil column confirmed that this strategy is suitable for the large-scale remediation of contaminated soil.
研究领域:
环境科学
·
土壤化学
·
污染控制
·
化学工程
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yan Liu,Yuetao Zhang,Zijie Li,Zhiqi Li,Shaoke Zhou,Yong Xia,Lei Mou
Rapid, accurate, and cost-effective strategies for the multiplexed and quantitative detection of multiple infectious disease biomarkers are still lack in hospital. Here, we introduce a multiplexed screen-printed electrode for the simultaneous detection of three infectious disease biomarkers: HBsAg, anti-HIV, and anti-TP. The electrode modified with in-situ deposition of gold nanoparticles (AuNPs) and MXene multilayered nanosheets. Comprehensive characterization confirms the morphology and electrochemical response of the AuNPs&MXene modified screen-printed electrode (AuNPs&MXene-SPE). AuNPs&MXene composite contributes to enhance sensitivity by maximizing surface area and improving electron transfer efficiency. The AuNPs&MXene-SPE exhibits outstanding detection performance for HBsAg, anti-HIV, and anti-TP. The AuNPs&MXene-SPE sensors achieve broad detection ranges (0.05–1000 ng/mL for HBsAg, 0.35–140 ng/mL for anti-HIV, and 0.25–100 ng/mL for anti-TP) accompanied by low limits of detection (0.01, 0.11, and 0.10 ng/mL, respectively). Applied to standard serum samples, the sensors showcase precision with relative standard deviations consistently below 5.0 %, affirming their suitability for complex solution environments. These sensors offer notable advantages, including cost-effectiveness, rapid response, high sensitivity, and specificity, eliminating the necessity for expensive equipment, which open avenues for the realization of point-of-care testing (POCT).
研究领域:
电化学
·
生物传感器
·
纳米材料
·
传染病
·
即时检测
✓ 已验证
产品关联
DOI
高影响因子
Materials Express
·
2023
·Vol. 13
·期 12
·2092-2100
·
IF 0.7
Liu Qin
Renal injury, which is a prevalent condition, significantly impacts the health of competitive wrestlers. However, there is a limited number of therapeutic methods and drugs available for its treatment. To tackle this issue, a renal targeted drug based on functionalized polymer nanoparticles
(FPNPs) is being studied. The primary methods in the preparation of FPNPs involve utilizing the thin film hydration technique to create nanoparticles and encapsulating the drug TP within them as a treatment for renal injury, thus forming TP-FPNPs. Subsequently, the renal targeting of TP-FPNPs
is analyzed using in vitro organ fluorescence imaging techniques. Furthermore, a renal IRI model is constructed to assess the pharmacokinetics of TP-FPNPs using the application method. The preparation results of TP-FPNPs reveal a hydrated particle size of approximately 90 nm, which
remains in the renal region for over 48 hours. Additionally, the concentration content surpasses that of other organs by more than threefold after 12 hours. Moreover, in the application results, TP-FPNPs continue to possess a concentration of 302.5 ng/g even after 48 hours post-injection.
Based on the aforementioned results, it can be concluded that TP-FPNPs exhibit specific targeting, biocompatibility, and an extended retention time. Thus, this study is expected to effectively achieve the effect of treating renal injury in martial arts athletes, establishing an experimental
foundation for its clinical treatment.
研究领域:
纳米技术
·
药学
·
肾病学
·
运动医学
✓ 已验证
DOI
高影响因子
AQUACULTURE
·
2023
·
IF 4.5
Tingting Ye,Min Li,Yuanbin Lin,Zengjian Su
Aquaculture has expanded significantly in recent years, and the effluent it produces has had a significant negative impact on the environment. The survival and growth rates of aquaculture products may impact by the eutrophication of the water body if the effluent from aquaculture is not handled. In this study, chitosan-based aerogel was used as a carrier to immobilize the degrading bacteria, and the adsorption capacity of the carrier material for methyl blue was 1.30 mg·g −1 . The Caulerpa lentillifera was added to the shrimp tank at the same time as a biofilter , and a composite in-situ treatment system using microbes and macroalgae was built to handle the effluent from the mariculture industry to test the reduction rates of the nutrients from the wastewater. The outcomes demonstrated that the immobilized bacteria used had reduction rates of COD , NH 4 + and NO 2 − in wastewater that were 48.82%, 9.14% and 40.74% greater than those of the free bacteria, respectively. The reduction effect of macroalgae for nutrients in wastewater is also very ideal, in which the reduction rates of TP and TN reach 32.43% and 74.94% respectively. When the immobilized degrading bacteria and macroalgae are combined, the reduction rates of COD, TN and TP in water reach 68.61%, 59.03% and 34.25%. At the same time, the survival rate of shrimp and the biomass of macroalgae have increased to a positive extent, with increases of 12.5% and 140%, respectively. These results demonstrate that the introduction of immobilized degrading bacteria and macroalgae into the shrimp culture system can effectively reduce the accumulation of nutrients in the shrimp culture system and have a positive impact in a variety of ways.
研究领域:
环境科学
·
水产养殖
·
废水处理
·
生物技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CATALYSIS
·
2022
·
IF 8.047
Minjie Xu,Xianglin Liu,Guiyao Song,Yingying Cai,Bianfang Shi,Yitao Liu,Xiaoxu Ding,Zixu Yang,Pengfei Tian,Chenxi Cao,Jing Xu
Different iron species exhibit distinct activity and selectivity in CO 2 hydrogenation reaction. Herein, by controlling calcination temperature, Fe-Al interaction in Na promoted Fe-Al catalysts has been regulated, which further leads to various compositions of iron oxide (FeO x ) and iron carbides (Fe 7 C 3 and Fe 5 C 2 ) after CO activation and CO 2 hydrogenation reaction. The phase compositions and structures of Fe-Al catalysts are carefully distinguished by multiple characterizations, including XRD, XPS, MES and TEM, and the reactivity of different phases is studied with the combination of experiments (kinetics, TP and in situ DRIFTS) and Density Functional Theory (DFT) calculations. Our FeAl350 with the highest FeC x content shows the highest CO 2 conversion of 48.2% and the lowest CO selectivity of 10.1%, and FeAl900 with the highest Fe 5 C 2 / FeC x ratio presents the highest C 5+ selectivity of 44.6%. Finally, a correlation between different compositions of iron species with the activity and selectivity of Fe-based for CO 2 hydrogenation to olefins was established.
研究领域:
催化
·
化学工程
·
材料科学
·
环境化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）