WEAR
·
2024
·
IF 5.3
Yanfei Liu,Zhikai Fan,Shengtao Yu,Ruize Zhang,Xiangyu Ge,Wenzhong Wang
MoS 2 –Sb 2 O 3 coating is commonly used as solid lubricant for titanium alloys , but the wear-resistance performance is still limited. Core-shell annealed nanodiamond (AND) particle is used as reinforcement for MoS 2 –Sb 2 O 3 coating on Ti6Al4V substrate treated by plasma electrolytic oxidation (PEO) and laser surface texturing (LST). The incorporation of AND particles into the MoS 2 –Sb 2 O 3 coating results in a 39 % decrease in friction and significantly reduces wear on the composite coating . Structural transformation of AND particles to amorphous carbon and graphitic structure promotes the densification of top-layer coating, enhancing lubrication and wear-resistance. Change of contact stress by PEO-LST promotes the formation of dense tribofilm and re-orientation of MoS 2 . This study has implications for the development of solid lubrication coatings for aerospace applications through functional nanomaterials and targeted designed surfaces.
研究领域:
材料科学
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表面工程
·
纳米技术
·
机械工程
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产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Zhiwei Su,Yi Ren,Yanwen Zhou,Caibo Yan,Tingdong Ren
To improve the biological fouling and corrosion resistance of Ti6Al4V (TC4) in marine environments, copper-containing titanium dioxide (TiO 2 (Cu)) films were prepared by magnetron sputtering TiO 2 (Cu) powder targets. The morphologies of the films showed that they became rough and coarse from 1.6 nm of the TiO 2 film to approximately 9 nm of the TiO 2 (Cu) films, which might be owing to the increase in the deposition rates from 1.33 to 2.08 nm/min. No diffraction orientations of the TiO 2 and Cu phases were found compared to those of the TiO 2 (Cu) powder. Ti, O, and Cu were detected using X-ray photoelectron spectroscopy to confirm the composition of the films. The ratio of Cu 2+ increased as the Cu content of the films increased, whereas that of Cu/Cu + scarcely changed. The TiO 2 and TiO 2 (Cu) films exhibited photocatalytic effects and their photocatalytic intensities decreased as the Cu content increased. Hydrophobicity was enhanced by the addition of Cu to the film. The antibiological fouling effect of the TiO 2 (Cu) films remained unchanged as the Cu/Ti ratio varied. Compared with those of TC4 , the corrosion current densities of the TiO 2 (Cu) films decreased by one order of magnitude and the corrosion potentials increased by 350 mV in artificial seawater , indicating that the corrosion resistance of TiO 2 (Cu)/TC4 was improved. Importantly, Cu was in abundance in the films for both antibiological and corrosion resistance functions owing to the saturated ratio of Cu/Cu + irrespective of the Cu/Ti ratio in the films.
研究领域:
材料科学
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海洋工程
·
生物医学
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产品关联
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
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2016
·
IF 3.42
Xiangmei Liu,H.C. Man
For titanium alloy implants, both surface bioactivity and antibacterial infection are the two critical factors in determining the success of clinical implantation of these metallic implants. In the present work, a novel nanocomposite layer of nano-silver-containing hydroxyapatite (Ag-HA) was prepared on the surface of biomedical Ti6Al4V by laser processing. Analysis using SEM, EDS and XRD shows the formation of an Ag-HA layer of about 200 μm fusion bonded to the substrate. Mineralization tests in simulated body fluid (SBF) showed that laser fabricated Ag-HA nanocomposite layer favors the deposition of apatite on the surface of the implants. Antibacterial tests confirmed that all Ag-HA nanocomposite layers can kill bacteria while a higher Ag content would lower the cytocompatibility of these coatings. Cell viability decreases when the Ag content reaches 5% in these coatings, due to the larger amount of Ag leached out, as confirmed by ion release evaluation. Our results reveal that laser fabricated Ag-HA nanocomposite coatings containing 2% Ag show both excellent cytocompatibility and antibacterial capability.
研究领域:
生物医学工程
·
材料科学
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表面工程
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产品关联
DOI
PubMed
高影响因子
Small
·
2025
·
IF 12.1
Zhuo Chen,Zheyun Cao,Zisheng Li,Guoqiang Liu,Feng Zhou,Weimin Liu
While titanium alloys like Ti6Al4V for joint implant are noted for their high strength, low density, and excellent biocompatibility, their clinical application is often hindered by poor wear resistance and insufficient bioactivity. Although various surface modification strategies have been explored to address these issues, the results have remained less than optimal. The purpose of this study is to develop a more effective strategy to maximize the function of Ti6Al4V as joint implant material. Hence, a photothermal lubricating composite hydrogel coating combining load-bearing micropores and hydrophilic polymer brushes is introduced on the Ti6Al4V surface. This microporous frame not only maintains the mechanical stability of the composite coating but also acts as a water reservoir, continuously replenishing water to the friction interface. The polymer brushes grafted within the micropores establish a stable hydration layer, significantly enhancing hydration lubrication performance of the composite coating. Furthermore, the composite coating can generate localized heat under near-infrared light due to its inherent photothermal effect, enabling rapid bacterial elimination and offering a strategy to reduce the risk of tissue infection. This multi-modification approach endows the composite coating with wear resistance, ultralow friction, and efficient antibacterial properties, enabling Ti6Al4V to achieve their maximum efficacy in the biomedical field.
研究领域:
生物医学工程
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材料科学
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表面改性
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骨科植入物
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生物材料
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产品关联
DOI
PubMed
高影响因子
SURFACE & COATINGS TECHNOLOGY
·
2021
·
IF 4.158
Dexin Chen,Yaoxin Li,Xueyang Zhao,Hongyuan He,Guodong Sun,Wei Li,Xiaojian Wang
In this study, different surface textures (Diamond, Cylinder, and Sin) have been designed and produced on Ti6Al4V alloys by selective laser melting technology. TiO 2 /Ag composite coatings were prepared on these textures by merging anodic oxidation and spray deposition methods. Tightly arranged TiO 2 nanotubes (TNTs) with tube diameters of about 100 nm are found on the top and lateral sides of the textures. On the bottom of the textures, dense nanopores were found with a pore diameter of about 50 nm. Compared with the untreated titanium alloy surface, both texture and TNTs structures would endow the titanium alloy surfaces with higher in vitro bioactivity. All three textures have an enhanced antibacterial property and a complete bactericidal effect was achieved by spray deposition of Ag nanoparticles (AgNPs) on all the surfaces. The MC3T3-E1 cells can adhere to the surfaces and proliferate normally, indicating good cytocompatibility of TiO 2 /Ag surfaces. Besides, the deposited AgNPs have been found to promote cell proliferation .
研究领域:
材料科学
·
生物材料
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生物医学工程
·
表面工程
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DOI
高影响因子
Journal of Materials Research and Technology-JMR&T
·
2023
·
IF 6.4
Yuyu Liu,Wei Jiang,Zheng Chen,Quan Xu,Zhiliang Zhang,Jianying He
Due to the intrinsically ultrahigh cooling rate and thermal gradient during laser melting deposition (LMD), columnar-to-equiaxed transition (CET) of grains has been a significant challenge in titanium-based alloys. In this study, two strategies, including the optimization of processing parameters and the addition of ceramics particles, were utilized to promote the CET of Ti6Al4V. The optimal processing parameters of Ti6Al4V were confirmed by response surface methodology (RSM). The width of prior β grains effectively decreases under the minimum dilution of single track. Besides, different contents of TiB 2 and La 2 O 3 were added to Ti6Al4V powder and the in situ (TiB + La 2 O 3 )/Ti6Al4V composites were manufactured using the identified optimal processing parameters. In situ TiB whiskers segregating at the grain boundaries tailor the coarse columnar to equiaxed grains with La 2 O 3 particles dispersed in the composites. With increasing formation of the reinforcements, equiaxed grain size decreases from 23.3 to 11.9 μm. The ultimate tensile strength of the components was improved by 19.6% and 26.4% compared to that of Ti6Al4V. This work provides systematic solutions to suppress the coarse columnar grains and refine the microstructure for titanium-based alloys.
研究领域:
材料科学
·
冶金工程
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产品关联
DOI
高影响因子
TRIBOLOGY INTERNATIONAL
·
2026
·
IF 7.6
Ye Wang,Zhengxuan Hu,Guolong Wu,Qiandi Peng,Qunli Zhang,Jianhua Yao,Wen Han,Chen Wen
To improve the wear resistance of titanium alloy, this study proposes a novel approach that combines laser irradiation and ZrO 2 nanoparticle (NP) doping in the fabrication of wear-resistant micro-arc oxidation (MAO) coating on Ti6Al4V (TC4) alloy. The obtained coatings were characterized by using laser scanning microscopy, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) to analyze their surface morphologies, microstructure and chemical compositions. Tribological properties were evaluated via ball-on-disk sliding wear tests, along with the hardness and adhesion of the coating. The results show that the MAO coating prepared under laser irradiation and ZrO 2 nanoparticle doping (NA- L -MAO) exhibits enhancement in density, uniformity and thickness compared with nanoparticle-doped MAO (NA-MAO) or laser-assisted MAO ( L -MAO) alone. Compared with the MAO coating, the NA- L -MAO coating achieves a porosity of only 4.67%, representing a reduction of ∼41.3%. Meanwhile, its volumetric wear rate reaches 3.56 × 10 −5 mm 3 ·N −1 ·m −1 , which is decreased by ∼88.3% and nearly one order of magnitude lower than that of the MAO coating. The ZrO 2 nanoparticles participate in coating growth via melting or embedding behaviours, enabling filling of micropores and increasing coating thickness. Due to laser irradiation, more ZrO 2 nanoparticles enter the NA- L -MAO coating, and more stable phases (rutile-TiO 2 and t-ZrO 2 ) are formed. Simultaneously, laser irradiation promotes uniform coating growth, lower surface roughness and enhanced coating adhesion. The synergistic effect of laser irradiation and nanoparticle incorporation facilitates more particle penetration into the coating, elevates coating hardness and thus improves the anti-wear performance of the coating.
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2026
·
IF 5.9
Wei Ma,Xinyue Zhang,Jiajia Cen,Qin Chen,Kai Chen,Cunao Feng,Hongyu Zhang,Dekun Zhang
Efficient bone regeneration requires scaffolds that combine mechanical strength with controlled osteoinductive factor delivery. Here, we present a porous Ti6Al4V scaffold (PXTC4) functionalized with polydopamine and integrated with dual-level BMP2–PLA–Alg core–shell microspheres (BMP2-HPLA-Alg) for sustained BMP2 release. The PXTC4 scaffold exhibited high porosity (∼75%) and an elastic modulus (∼6.5 GPa) compatible with cortical bone, while the microspheres ensured heparin-mediated BMP2 adsorption, tunable degradation, and reduced initial burst release by 53.5% compared to the single-level BMP2-Alg microspheres. In vitro studies demonstrated enhanced MC3T3-E1 adhesion, proliferation, cytoskeletal organization, early osteogenic differentiation, and late-stage matrix mineralization. These results indicate that BMP2 synergizes with scaffold topography to create a favorable osteogenic microenvironment. This BMP2-HPLA-Alg microsphere-functionalized porous Ti6Al4V scaffold provides a robust platform with mechanical stability and sustained pro-osteogenic activity, offering a promising strategy for bone regeneration that warrants further in vivo investigation.
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DOI
PubMed
高影响因子
Materials
·
2024
·Vol. 17
·期 15
·3812
·
IF 3.1
Shaohong Liu,Hairui Liu,Limin Zhou,Hao Cui,Manmen Liu,Li Chen,Ming Wen,Haigang Dong,Feng Liu,Wei Wang,Song Li
A novel AgCuTi brazing foil with a unique microstructure was developed, which could achieve strong vacuum brazing of Ti6Al4V (TC4) and sapphire. The brazing foil was composed of Ag solid solution (Ag(s,s)), Cu solid solution (Cu(s,s)), and layered Ti-rich phases, and had a low liquidus temperature of 790 °C and a narrow melting range of 16 °C, facilitating the defect-free joining of TC4 and sapphire. The sapphire/TC4 joint fabricated by using this novel AgCuTi brazing foil exhibited an outstanding average shear strength of up to 132.2 MPa, which was the highest value ever reported. The sapphire/TC4 joint had a characteristic structure, featuring a brazing seam reinforced by TiCu particles and a thin Ti3(Cu,Al)3O reaction layer of about 1.3 μm. The fracture mechanism of the sapphire/TC4 joint was revealed. The crack originated at the brazing seam with TiCu particles, then propagated through the Ti3(Cu,Al)3O reaction layer, detached the reaction layer from the sapphire, and finally penetrated into the sapphire. This study offers valuable insights into the design of active brazing alloys and reliable metal–ceramic bonding.
研究领域:
材料科学
·
焊接工程
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DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Junjie Deng,Rufang Wei,Haofeng Qiu,Xiang Wu,Yanyu Yang,Zhimao Huang,Jiru Miao,Ashuang Liu,Haiyang Chai,Xiao Cen,Rong Wang
Restoration of the lubrication functions of articular cartilage is an effective treatment to alleviate the progression of osteoarthritis (OA). Herein, we fabricated chitosan- block -poly(sulfobetaine methacrylate) (CS-b-pSBMA) copolymer via a free radical polymerization of sulfobetaine methacrylate onto activated chitosan segment, structurally mimicking the lubricating biomolecules on cartilage. The successful copolymerization of CS-b-pSBMA was verified by Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and 1 H nuclear magnetic resonance. Friction test confirmed that the CS-b-pSBMA copolymer could achieve an excellent lubrication effect on artificial joint materials such as Ti6Al4V alloy with a coefficient of friction as low as 0.008, and on OA-simulated cartilage, better than the conventional lubricant hyaluronic acid, and the adsorption effect of lubricant on cartilage surface was proved by a fluorescence labeling experiment. In addition, CS-b-pSBMA lubricant possessed an outstanding stability, which can withstand enzymatic degradation and even a long-term storage up to 4 weeks. In vitro studies showed that CS-b-pSBMA lubricant had a favorable antibacterial activity and good biocompatibility. In vivo studies confirmed that the CS-b-pSBMA lubricant was stable and could alleviate the degradation process of cartilage in OA mice. This biomimetic lubricant is a promising articular joint lubricant for the treatment of OA and cartilage restoration.
研究领域:
材料科学
·
生物医学工程
·
骨科
·
组织工程
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产品关联
DOI
PubMed
高影响因子
Biomaterials Advances
·
2022
·
IF 0
Yanxi Li,Yanjin Lu,Bingrun Qiu,Yiting Ze,Peiran Li,Yu Du,Ping Gong,Jinxin Lin,Yang Yao
Poor vascularization was demonstrated as a factor inhibiting bone regeneration in patients receiving radiotherapy. Various copper-containing materials have been reported to increase angiogenesis, therefore might improve bone formation. In this study, a Ti6Al4V-1.5Cu alloy was prepared using selective laser melting (SLM) technology. The immunomodulatory and pro-angiogenic effects of the Ti6Al4V-1.5Cu alloys were examined. In vitro , Ti6Al4V-1.5Cu stimulated vascular formation by restraining inflammatory factors and provoking angiogenic factors in non-irradiated and irradiated macrophages. In vivo , the angiogenic effects of the Ti6Al4V-1.5Cu alloy were confirmed using an irradiated rat femur defect model. Moreover, we found that the biological effects of the Ti6Al4V-1.5Cu alloy were partially due to the release of copper ions and associated with PI3K-Akt signaling pathway. In conclusion, this study indicated the potential of the Ti6Al4V-1.5Cu alloy to promote angiogenesis by releasing copper ions and inhibiting inflammation in normal and irradiated tissues.
研究领域:
材料科学
·
生物材料
·
组织工程
·
免疫学
·
生物医学工程
✓ 已验证
DOI
PubMed
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