ACS Applied Nano Materials
·
2019
·
IF 0
Xian Fang,Xiaoyan Chen,Ying Liu,Qiuju Li,Zhongrun Zeng,T. Maiyalagan,Shun Mao
Rapid determination of trace antibiotics is critical for environmental monitoring and the ecosystem. In this study, a sensitive and selective electrochemical sensor for ciprofloxacin (Cip) detection by anodic stripping voltammetry of Cu2+ is designed. Zr(IV)-based metal–organic framework (MOF) NH2–UiO-66 and reduced graphene oxide (RGO) composites are used as working electrodes, which have a large surface area with porous structure and high electrical conductivity. Because Cip can form a stable composite with Cu2+ due to the complexation reaction, the anodic stripping voltammetry method is used for Cip determination with Cu deposition on the NH2–UiO-66/RGO-modified electrode. When Cip is present, the oxidization current of Cu2+ decreases significantly due to the formation of Cu2+–Cip complex. The prepared NH2–UiO-66/RGO sensor can detect trace levels of Cip down to 6.67 nM with a sensitivity of 10.86 μA μM–1, and a linear working range from 0.02 to 1 μM, which is superior to other electrochemical Cip sensors reported previously. The sensor also shows high selectivity, reproducibility, and stability in Cip sensing. Meanwhile, the electrochemical sensor is capable to detect Cip in real water samples with satisfactory recoveries. The ultrasensitivity, rapid detection, and easy operation of the reported sensors present significant potentials for real-time analysis and monitoring of trace antibiotic contaminants in water.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
ANALYTICAL CHEMISTRY
·
2020
·
IF 6.785
Wei Zhang,Xiaolei Liu,Ping Li,Wen Zhang,Hui Wang,Bo Tang
Elucidating the relationship between glycosylation and phosphorylation of protein post-translational modifications is of great significance for understanding most diseases. Mass spectrometry has been widely used in research of protein phosphorylation and glycosylation. However, to realize in situ and dynamic analysis of the levels of phosphorylation and glycosylation in cells and in vivo, mass spectrometry still has certain difficulties. Herein, a nano-MOF-based fluorescent probe with Zr(IV) and boric acid as the active center was designed and prepared. Fluorescence detection and imaging of phosphate is achieved through the specific interaction of Zr(IV) and phosphate. With aim to achieve specific recognition of glycosylation sites, the boronic acid group was modified in the MOF structure, and the fluorescence of the MOFs was regulated by the alizarin red. Thus, the glycosylation sites were recognized by the competition between alizarin red and glycosyl. Finally, the nanoprobe was successfully applied for in situ fluorescence imaging of the levels of glycosylation and phosphorylation in depressed mice.
研究领域:
生物医学工程
·
分子生物学
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神经科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2024
·
IF 8.1
Guangli Yu,Fei Ni,Wenyue Niu,Yu Chen,Feng Zhang,Guo-Dong Li,Xingfei Song,Yajing Zhang,Kangjun Wang
Metal-organic frameworks (MOFs) recently gained immense popularity for the adsorption of organic impurities. In this work, the adsorptive separation of bisphenol A (BPA) from aqueous mixtures was explored utilizing three types of zirconium-based MOFs, namely MOF-808, UiO-66, and hierarchically porous UiO-66 (HP-UiO-66). The HP-UiO-66, which was etched by sodium acetate as the terminal ligand, generated large mesopores ranging from 40 to 300 Å due to the departure of partial linkers and metallic clusters. The adsorption ability for BPA increased significantly with the introduction of numerous mesopores onto the HP-UiO-66 framework, even though the surface area of HP-UiO-66 was lower compared to that of the pristine UiO-66 and MOF-808. The study revealed that the maximum adsorption capacities ( q ) for BPA by HP-UiO-66 reached up to 295.04 mg g −1 , which was about 88.5% and 17.4% higher in comparison to UiO-66 and MOF-808, respectively. Furthermore, the q value of HP-UiO-66 was also better than many other previously reported MOF adsorbents. The analysis of possible adsorption mechanisms indicated that physical pore-filling was anticipated as the principal mechanism, attributed to the larger window size and high mesopore surface area of HP-UiO-66. Furthermore, X-ray photoelectron and Fourier transform infrared spectroscopic measurements inferred that the synergetic effects of H-bonding and π-π interactions played crucial roles in BPA capture as well. Overall, this study revealed a structure–property relationship in the Zr-MOFs-based adsorbents and opened up a new avenue to exploit unique MOF platforms for the efficient removal of emerging contaminations in the future.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS
·
2016
·Vol. 16
·期 10
·1674
·
IF 2.033
Wenjing Qi,Zhongyuan Liu,Wei Zhang,Mohamed Ibrahim Halawa,Guobao Xu
Zr(IV) can form phosphate and Zr(IV) (–PO32−–Zr4+–) complex owing to the high affinity between Zr(IV) with phosphate. Zr(IV) can induce the aggregation of gold nanoparticles (AuNPs), while adenosine triphosphate(ATP) can prevent Zr(IV)-induced aggregation of AuNPs. Herein, a visual and plasmon resonance absorption (PRA)sensor for ATP have been developed using AuNPs based on the high affinity between Zr(IV)with ATP. AuNPs get aggregated in the presence of certain concentrations of Zr(IV). After the addition of ATP, ATP reacts with Zr(IV) and prevents AuNPs from aggregation, enabling the detection of ATP. Because of the fast interaction of ATP with Zr(IV), ATP can be detected with a detection limit of 0.5 μM within 2 min by the naked eye. Moreover, ATP can be detected by the PRA technique with higher sensitivity. TheA520nm/A650nmvalues in PRA spectra increase linearly with the concentrations of ATP from 0.1 μM to 15 μM (r = 0.9945) with a detection limit of 28 nM. The proposed visual and PRA sensor exhibit good selectivity against adenosine, adenosine monophosphate, guanosine triphosphate, cytidine triphosphate and uridine triphosphate. The recoveries for the analysis of ATP in synthetic samples range from 95.3% to 102.0%. Therefore, the proposed novel sensor for ATP is promising for real-time or on-site detection of ATP.Keywords:gold nanoparticles;adenosine triphosphate;plasmon resonance absorption;sensor
研究领域:
生物化学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Laser & Photonics Reviews
·
2025
·
IF 10
Hui Peng,Wei Tian,Qilin Wei,Linghang Kong,Guang Dai,Jialong Zhao,Bingsuo Zou
Recently, Sb 3+ -activated 0D Zr(IV)-based metal halides have gained enormous attention for their unique optical properties. However, realizing efficient white emission and multiple reversible emissions in a single system remains a great challenge. Parallelly, the currently reported Sb 3+ -activated Zr(IV)-based organic metal halides are mainly through aimless regulation of the type of A-site organic cations, severely limiting their development. Herein, all-inorganic Cs 2 ZrCl 6 :Sb 3+ is employed as the conformational model, three different compounds of Sb 3+ -doped [18-crown-6@A] 2 ZrCl 6 (A = K, Rb, Cs) are developed via supramolecular assembly. All compounds show efficient tunable white emission with luminous efficiency of 91.28% for [18-crown-6@K] 2 ZrCl 6 :Sb 3+ , 84.84% for [18-crown-6@Rb] 2 ZrCl 6 :Sb 3+ , and 78.63% for [18-crown-6@Cs] 2 ZrCl 6 :Sb 3+ , which shall stem from Sb 3+ -induced multi-exciton emission in [SbCl 6 ] 3− octahedron. Particularly, the strong supramolecular interaction can enhance the structural rigidity and suppress nonradiative transitions, which is the dominated reason for [18-crown-6@A] 2 ZrCl 6 :Sb 3+ exhibits efficient emission. The component/excitation/temperature/moisture-dependent multiple reversible PL switching characteristics are observed in Sb 3+ -doped [18-crown-6@A] 2 ZrCl 6 , which allows to demonstrate their applications in advanced optical anti-counterfeiting and information encryption. Moreover, a single-component white light-emitting diode is also fabricated, which shows a high color rendering index of 96.1. Therefore, the work provides a feasible scheme for designing organic Zr(IV) halides with fascinating optical properties.
研究领域:
材料科学
·
光学工程
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2023
·Vol. 19
·期 36
·2302357
·
IF 13.3
Zhilin Li,Mengyan Cao,Zhihui Rao,Xiujian Zhao,Xiao Gong
Low-dimensional hybrid metal halide (LDHMH) materials have attracted considerable attention owing to their intriguing optical properties. To the best of the knowledge, this is the first study to successfully demonstrate both self-trap exciton (STE) and afterglow emissions in Zr-based LDHMH materials. The obtained pure (Ph 3 S) 2 ZrCl 6 crystals showed near-ultraviolet phosphorescence and a green afterglow owing to the organic cation Ph 3 S + , while the Bi-doped and Sb-doped crystals exhibited both STE and afterglow emissions. However, the Te-doped crystals showed only a broad yellow STE emission owing to the [TeCl 6 ] 2− octahedron. In addition, all the crystals showed good stability. Notably, Sb-doped crystals produced white light, which can be adjusted between cold white and warm white using different excitations. Finally, this strategy for both STE and afterglow emissions can be applied to other LDHMH materials for optical applications.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Cleaner Production
·
2023
·
IF 11.1
Junchao Wang,Yongbo Chen,Jinwei Zhang,Gongyan Liu
Zirconium tanning agent, which is mainly composed of low-toxic tetravalent zirconium (Zr 4+ ) salts, has been considered the most promising eco-friendly tanning agent for leather manufacturing, due to its comparable tanning performance with trivalent chrome. However, in the initial penetration stage of the zirconium tanning process, macromolecular multinuclear complexes are commonly formed because of the rapid coordination between hydrated Zr 4+ , which can easily cross-link with active groups of neighboring collagen fibers and thus block subsequently even penetration of zirconium tanning agents, resulting in surface over-tanning and ununiform tanning effects. Herein, to address the aforementioned issues of conventional zirconium tanning, inert-surface modification of collagen fibers was proposed by using PEGylated epoxy copolymers (PEGMA-co-GMA, defined as PPG) to pretreat bated hide, based on the covalent reactions and hydrogen-bond interactions of PPG with amino and carboxyl groups on collagen fibers, respectively. After modification, the surface reactivity of skin collagen was significantly reduced, which was able to delay the cross-linking interactions with zirconium tanning agents and thus promote uniform penetration. Simultaneously, the extra hydroxyls produced from the ring-open reactions of epoxy groups could also mitigate the excessive coordinated complexation of hydrated Zr 4+ , leading to efficient penetration of zirconium tanning agents. Compared with conventional zirconium tanning, research results showed that this inert-surface modification strategy could comprehensively improve the overall leather performance with both efficient and uniform tanning effects. Moreover, the resultant leather qualities, including thermal stability, physical and mechanical properties, and organoleptic properties , are very comparable with chrome-tanned leather. In addition, attributing to the reaction between collagen amino and PPG, the use of sodium chloride was avoided, resulting in a cleaner salt-free pickling process. Altogether, this inert-surface modification strategy represents a significant step forward for effective and cleaner tanning technology , which will accelerate the wide application of Zr(IV) in place of traditional chrome tanning agents.
研究领域:
皮革化学与工程
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材料科学
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生物化学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2021
·
IF 6.953
Jingjing Wang,Jun Wei
Zr(IV)-crosslinked carboxymethyl cellulose/carboxymethyl chitosan hydrogels were prepared using polyethylene glycol (PEG) as pore-forming agent. The hydrogels exhibited porous structure and the pore size increased with the PEG content. The obtained hydrogels were used as adsorbents for removal of phosphate from aqueous solutions. The hydrogel prepared with most amount of PEG displayed largest adsorption amount of phosphate. This result might be attributed to improvement of surface area and pore volume caused by introduction of PEG, which could boost exposure of adsorption sites in the hydrogel and enhance the diffusion of phosphate into interior of the hydrogel. The phosphate adsorption achieved equilibrium within 400 min and the removal process followed pseudo-second-order kinetic model. The maximum adsorption capacity was reached at pH = 2.0, and the adsorption capacity gradually increased with temperature. In the presence of coexisting anions, SO 4 2− ions exerted much more negative effect on phosphate adsorption than Cl − and NO 3 − ions. The phosphate adsorption mechanism was related to electrostatic interaction, ligand exchange and ion exchange. Moreover, the hydrogel exhibited relatively stable adsorption capacity after six adsorption/desorption cycles. The present study presented a facile method for preparing an excellent hydrogel adsorbent for phosphate removal from aqueous solutions.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2020
·
IF 5.339
Chao Xia,Yan Xu,Meng-Meng Cao,Yun-Peng Liu,Jin-Feng Xia,Dan-Yu Jiang,Guo-Hong Zhou,Rong-Jun Xie,Da-Feng Zhang,Hui-Li Li
In the present study, a kind of Eu(III) post-functionalized Zr(IV)-based metal-organic framework (UiO-66(COOH) 2 , Zr-MOF: Eu 3+ ) was synthesized and utilized as an independently luminescent probe for sensing bilirubin (BR) in human serum, a biomarker of jaundice hepatitis. It can be served as a turn-off fluorescent switch for BR because its red emission from Eu 3+ can be easily quenched by BR through a fluorescent resonant energy transfer (FRET) process between BR and its ligands, and as a result, BR is recognized successfully. Particularly, Zr-MOF: Eu 3+ has shown many appealing properties, such as high sensitivity, quick response (less than 1 min), broad response window (0–15 μM), and excellent selectivity. Most importantly, a kind of portable test paper based on Zr-MOF: Eu 3+ probe has been developed for directly assessing the level of BR in real human serum and further diagnosing bilirubin-related diseases via visually observing the luminescent color variation.
研究领域:
生物化学
·
医学诊断
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Electrochemical Science
·
2024
·
IF 1.3
Mengyuan Zhao,Yunhang Liu,Fang Li,Jiale Han,Volodymyr Dubovyk,Hongyuan Zhao
A simple and efficient ultrasonic-assisted strategy was used to prepare the nanocomposite of Vulcan XC-72R carbon (VXC-72R) nanoparticles and Zr(IV)-based metal-organic framework (UIO-66) nanoparticles. For the multifunctional VXC-72R@UIO-66 nanocomposite, VXC-72R nanoparticles possessed good conductivity property and good dispersion, which were conductive to form the interconnected carbon conductive channels; UIO-66 nanoparticles could improve the accumulation ability of methyl parathion (MP) because of the high affinity of Zr-O groups with phosphoric groups. Moreover, the introduction of VXC-72R nanoparticles could effectively make up the conductivity property of UIO-66 nanoparticles. The VXC-72R@UIO-66/GCE sensor presented good MP detection performance with limit of detection (LOD) of 1.35 nM (Linear MP concentration range: 0.01–10 μM). When used for the detection of MP in juice samples, the VXC-72R@UIO-66/GCE sensor showed acceptable recoveries of 96.00–104.67 %.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ELECTROANALYSIS
·
2021
·Vol. 34
·期 4
·701-708
·
IF 3.223
Jing Chen,Shuying Li,Fanghong Xu,Qian Zhang
Widely presented nitrite in drinking water, food and even physiological system endangers human health. Here,bare gold nanoparticles functionalized Zr-based metal-organic framework modified reduced graphene oxide (GNPs/UiO-66-NH 2 /rGO) nanocomposites were prepared by hydrothermal method. This experiment studies the morphology, composition, structure and electrochemical behavior of the sensor. The experimental results show that the sensor has a peak potential of 0.9 V, the concentration range of NO 2 − is 5.0 μM to 768 μM, the linear regression equation of the calibration curve is I pa =0.3646+0.00642 C (R 2 =0.9998), and the LOD is as low as 3.7 μM (S/N=3). Therefore, an electrochemical sensor platform for trace detection of NO 2 − was successfully constructed.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Xing Cheng,Yue Tang,Xiaohuan Huang,Linghui Huang,Han Tao,Yuangen Wu
Artificial enzymes have attracted much attention in food analysis because of their simple preparation, low cost, and strong stability. However, the most used artificial enzymes are based on oxidoreductases such as oxidase, peroxidase, catalase, and laccase. There are few reports on hydrolases like phosphatase for food analysis. Herein, a novel green zirconium-glutamic acid (Zr(IV)-Glu) complex was prepared using Zr ions and glutamic acid. The Zr(IV)-Glu complex was first found to possess excellent phosphatase-like activity, which was used to establish a fluorescent sensor for detecting phytic acid (PA). The Zr(IV)-Glu complex can catalyze the hydrolysis of 4-methylumbellione phosphate disodium salt (4-MUP) to produce blue fluorescent products with fluorescence emission peaks at 448 nm. PA with six phosphate groups can attach on the surface of Zr(IV)-Glu to form Zr-O-P bond and inhibit the catalytic activity of Zr(IV)-Glu, leading to the decrease of fluorescence in the system. The change of fluorescent intensity at 448 nm was positively correlated with the PA content, so that a fluorescent sensor using the phosphatase-like activity of Zr(IV)-Glu was proposed to detect PA. The established sensor has high sensitivity, low detection limit (LOD) of PA to 58 μg·L -1 , strong anti-interference ability, and excellent selectivity. This work can provide a new method for PA detection in food and further expand the application of phosphatase mimics.
研究领域:
分析化学
·
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）