TALANTA
·
2014
·
IF 3.511
Qing Han,Xi Wang,Zaiyue Yang,Wanying Zhu,Xuemin Zhou,Huijun Jiang
Based on magnetic field directed self-assembly (MDSA) of Fe 3 O 4 @rGO composites, a novel magnetic molecularly imprinted electrochemical sensor (MIES) was fabricated and developed for the determination of the azo dye amaranth . Fe 3 O 4 @rGO composites were obtained by a one-step approach involving the initial intercalating of iron ions between the graphene oxide layers via the electrostatic interaction , followed by the reduction with hydrazine hydrate to deposit Fe 3 O 4 nanoparticles onto the reduced oxide graphene nanosheets . In molecular imprinting, the complex including the function monomer of aniline, the template of amaranth and Fe 3 O 4 @rGO was pre-assembled through π–π stacking and hydrogen bonding interactions, and then was self-assembled on the surface of magnetic glassy carbon electrode (MGCE) with the help of magnetic field induction before electropolymerization. The structures and morphologies of Fe 3 O 4 @rGO and the doped molecularly imprinted polymers (MIPs) were investigated by Fourier transform infrared spectrometer (FT-IR), Raman spectra and scanning electron microscope (SEM). Besides, the characterization by differential pulse voltammetry (DPV) showed that Fe 3 O 4 @rGO composites promoted the electrical conductivity of the imprinted sensors when doped into the MIPs. The adsorption isotherms and adsorption kinetics were employed to evaluate the performances of MIES. The detection of amaranth was achieved via the redox probe K 3 [Fe(CN) 6 ] by blocking the imprinted cavities, which avoided the interferences of oxidation products and analogs of amaranth. Furthermore, the prepared MIES exhibited good sensitivity, selectivity, reproducibility and efficiency for detecting amaranth in fruit drinks. The average recoveries were 93.15–100.81% with the RSD <3.0%.
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2022
·
IF 5.122
Yingying Xiang,Yujiao Tu,Lei Jiang,Lin Yuan,Ze Liu,Qiang Xie,Xuequan Xiong,Fei Song
As one of the most widely used azo synthetic dyes, long-term consumption of excessive amaranthcan cause a threat to health. It is very urgent to establish high selective and sensitive method for amaranth detection. Orange fluorescent carbon dots utilizing l -methionine and o-phenylenediamine as raw materials, namely S,N-CDs, were prepared via one-step hydrothermal method . Dialysis, thin layer chromatography and chromatographic column were employed for further purification. The purified dual-mode nanoprobe based on fluorescent and UV absorption was successfully established. For fluorescent, excellent linear ranges of 5–70 μM and 110–195 μM were obtained, and low detection limit was 345.22 nM. For UV absorption, excellent linear ranges of 0–155 μM with low detection limit 12.70 nM. It revealed that inner filter effect and static quenching dominated in amaranth quenching the fluorescent of S,N-CDs. Furthermore, the dual-mode nanoprobe could be efficiently applied to determine amaranth in fruit juice, carbonated drink, and strawberry jam samples. It provided a new insight on the purification of carbon dots and detection of amaranth by dual-mode nanoprobe.
研究领域:
食品科学
·
分析化学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2021
·
IF 4.464
Yiyong Wu,Guangli Li,Yaling Tian,Jinxia Feng,Jingyun Xiao,Jun Liu,Xia Liu,Quanguo He
A novel amaranth electrochemical sensor was produced by electrodepositing a molecularly imprinted polypyrrole film in the presence of amaranth on a multi-walled carbon nanotube (MWCNT) surface. Template molecules were completely eluted through an innovative strategy that only requires the application of a fixed electrical potential in a blank phosphate buffer solution. Obviously, this strategy is much faster and more eco-friendly. The molecularly imprinted polymer (MIP)-based electrochemical sensor was systematically investigated by scanning electron microscopy, atomic force microscopy, X-ray diffraction, cyclic voltammetry, and electrochemical impedance spectroscopy. The resultant MIP/MWCNT modified glass carbon electrode (MIP/MWCNT/GCE) shows satisfactory electroactive surface area and charge transfer resistance. As expected, the electrochemical response signals were significantly amplified at the MIP/MWCNT/GCE. Under optimal conditions, the proposed MIP/MWCNT/GCE exhibits extraordinarily good analytical performance for amaranth detection, with two wide detection ranges (0.007 μM to 1.0 μM, and 0.40 μM to 17 μM) and detection possible down to 0.4 nM. Moreover, the polypyrrole MIP films show high binding affinity and specifically identifies amaranth molecules, enabling the robust detection of amaranth in a complicated matrix with excellent selectivity, reproducibility, and stability. The proposed sensor achieves accurate detection of amaranth concentration in various fruit drinks with acceptable recovery.
研究领域:
分析化学
·
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Guanru Chang,Yunlong Wang,Baoyou Gong,Yazhong Xiao,Yan Chen,Shaohua Wang,Shikuo Li,Fangzhi Huang,Yuhua Shen,Anjian Xie
Integration of multimodal treatment strategies combined with localized therapy to enhance antitumor efficacy and reduce side effects is still a challenge. Herein, a novel composite hydrogel containing rGO, amaranth extract (AE) and gold nanoparticles (AuNPs) was prepared by using AE as both reductant and cross-linking agent. The chlorophyll derivatives in AE were also employed as a photodynamic therapy drug. Meanwhile, AuNPs and rGO both have obvious photothermal effects and can accelerate the generation of cytotoxic singlet oxygen (1O2). The temperature increase of rGO/AE/AuNPs precursor is up to 6.3 °C under 808 nm laser irradiation at a power density of 200 mW·cm–2. The hydrogel shell on in situ tumor cells was easily formed and regulated by near-infrared irradiation within 10 min, which could both retain a high concentration of drugs on the lesion site and prevent them from migrating to normal tissue, thus reducing the side effects. Compared with rGO/AE and AE, rGO/AE/AuNPs showed a remarkably improved and synergistic antitumor effect. The hydrogel possesses good biocompatibility and high hydrophilicity and could be used for loading chemotherapeutics, which provides a new approach for located and multiple antitumor therapies.
研究领域:
生物医学工程
·
纳米医学
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Qiaoyun Zhang,Weiwei Cheng,Di Wu,Yuling Yang,Xiao Feng,Chengcheng Gao,Linghan Meng,Xinchun Shen,Yan Zhang,Xiaozhi Tang
An electrochemical sensor was fabricated by modifying nanoporous gold (NPG)-coated glassy carbon electrode (NPG/GCE) with functionalized graphene oxide /chitosan/ionic liquid nanocomposites (fGO/CS/IL). The introduction of ionic liquid (IL) and chitosan (CS) induced higher dispersibility of functionalized graphene oxide (fGO), and was beneficial for the combination of fGO/CS/IL with NPG/GCE. As a result of the synergistic effect of NPG and fGO/CS/IL, the resulted functionalized graphene oxide/chitosan/ionic liquid nanocomposites/nanoporous gold /glassy carbon electrode (fGO/CS/IL/NPG/GCE) showed the highest redox peak current response signal of Amaranth (E123) due to ultrahigh surface area, electronic conductivity as well as the improvement of the surface structure. Under optimized conditions, the enhanced peak currents represented excellent analytical performance for detection of Amaranth in the concentration range from 8.0 to 1200.0 nM. Meanwhile, the fGO/CS/IL/NPG/GCE presented satisfactory sensitivity and selectivity, excellent reproducibility, and long-time stability. For practical applications, the fGO/CS/IL/NPG/GCE was validated for the determination of Amaranth in three types of drinks with satisfactory results.
研究领域:
分析化学
·
电化学
·
材料科学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 9
·631
·
IF 5.4
Li Jiejun,Wang Hui,Li Xinyi,Zhao Pengcheng,Fei Junjie,Xie Yixi
Amaranth (AM) is a widely used synthetic azo food colorant that poses severe toxicological risks upon excessive consumption, creating an urgent need for its ultra-sensitive detection. We report a high-performance electrochemical sensor based on the electrostatic co-aggregation of V 2 O 3 @NC and NHCS for the high-fidelity quantification of AM. A unique “capture-and-catalysis” synergistic mechanism governs this composite interface. Specifically, the highly porous NHCS framework provides exceptional capacity to capture and pre-concentrate target molecules while acting as a highly conductive “electronic bridge.” Subsequently, the abundant mixed-valence (V 3+ /V 5+ ) sites of the V 2 O 3 @NC serve as a robust electrocatalytic engine to drive the catalysis, significantly amplifying the AM oxidation signal. Combining electrochemical kinetic analysis with DFT calculations (including HOMO and MEP), we reveal that this electrocatalytic evolution proceeds via a directional 1 H + /2e − transfer mechanism. Under optimal conditions, the V 2 O 3 @NC/NHCS sensor exhibits a broad linear range (0.01–12 µM) and an extremely low LOD of 0.80 nM. Practical analysis of commercial beverages yielded recoveries of 95.0%–104.3%, with results perfectly matching orthogonal UV-Vis cross-validation. This work provides a robust platform for azo dye screening and profound insights into the rational design of “capture-and-catalysis” composite interfaces. Graphical abstract
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2014
·
IF 3.259
Meiling Wang,Yunqiao Gao,Qian Sun,Jianwei Zhao
In the present work, a novel strategy based on new carbon nanotube (CNT) and polypyrrole (ppy) composite modified electrode for the simultaneous determination of the isomers of Amaranth (E123) and Ponceau 4R (E124) was proposed. Due to the increasing dispersibility and effective surface area of the CNT caused by decoration of ppy to the CNT, the proposed electrode exhibited excellent electrochemical sensitivity and high selectivity toward the oxidation of Amaranth and Ponceau 4R. The linear response ranges for Amaranth and Ponceau 4R were 5.0 × 10 −9 M–5.0 × 10 −7 M, and 8 × 10 −9 M–1 × 10 −6 M and corresponding detection limits as low as 5.0 × 10 −10 M and 1.0 × 10 −9 M, respectively. This proposed method was successfully applied in the detection of Ponceau 4R and Amaranth in fruit drink samples.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Analytical Methods
·
2017
·Vol. 10
·期 9
·3149-3157
·
IF 2.038
Jing Shasha,Zheng Huijun,Zhao Li,Qu Lingbo,Yu Lanlan
A new sensitive electrochemical sensor based on poly(sodium 4-styrenesulfonate) (PSS) functionalized graphene and Co 3 O 4 nanoparticle clusters (PSS-GN/Co 3 O 4 ) ternary composite was fabricated via two-step synthesis. The PSS-GN/Co 3 O 4 nanocomposite significantly increased the oxidative activity of amaranth due to the individual merit and mutual effect of PSS-GN and Co 3 O 4 nanoparticle clusters which improved the performance of the electrochemical sensor with high sensitivity. Cyclic voltammetry (CV) and linear sweep voltammetry (LSV) measurements were used for the detection of amaranth. Under the optimal conditions, the oxidation peak currents of amaranth increased proportionally to the concentration within the range of 0.01–1.0 and 1.0–6.0 μmol L −1 , and the limit of detection was 4.0 nmol L −1 . The proposed modified electrode was highly sensitive and was successfully applied to determine amaranth in the soft drinks with satisfactory recoveries. The as-prepared PSS-GN/Co 3 O 4 /GCE electrochemical sensor offers a feasible way for designing simpler, low cost, and environment-friendly sensors based on Co 3 O 4 nanoparticle clusters.
研究领域:
分析化学
·
材料科学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
CHEMOSPHERE
·
2023
·
IF 8.8
Daying Chen,Lin Zhao,Danning Chen,Pengfei Hou,Jiashu Liu,Chuanbin Wang,Moses Akintayo Aborisade,Meilin Yin,Yongkui Yang
Efficient, stable, and easily producible electrodes are useful for treating dye wastewater through electrochemical oxidation . In this study, an Sb-doped SnO 2 electrode with TiO 2 nanotubes as the middle layer (TiO 2 -NTs/SnO 2 –Sb) was prepared through an optimized electrodeposition process. Analyses of the coating morphology, crystal structure, chemical state, and electrochemical properties revealed that tightly packed TiO 2 clusters provided a larger surface area and more contact points, which is conducive to reinforcing the binding of SnO 2 –Sb coatings. Compared with a Ti/SnO 2 –Sb electrode without a TiO 2 -NT interlayer, the catalytic activity and stability of the TiO 2 -NTs/SnO 2 –Sb electrode significantly improved ( P < 0.05), as reflected by the 21.8% increase in the amaranth dye decolorization efficiency and 200% increase in the service life. The effects of current density, pH, electrolyte concentration, initial amaranth concentration, and the interaction between various combinations of parameters on the electrolysis performance were investigated. Based on response surface optimization, the maximum decolorization efficiency of the amaranth dye could reach 96.2% within 120 min under the following set of optimized parameter values: 50 mg L −1 amaranth concentration, 20 mA cm −2 current density, and 5.0 pH. A potential degradation mechanism of the amaranth dye was proposed based on the experimental results of a quenching test, ultraviolet–visible spectroscopy, and high-performance liquid chromatography-mass spectrometry. This study provides a more sustainable method for fabricating SnO 2 –Sb electrodes with TiO 2 -NT interlayers to treat refractory dye wastewater.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2023
·
IF 8.8
Jingjuan Wang,Juan Wu,Mimi Sun,Jing Bai,Xiangjie Bo
This study presents the first integrated electrochemical platform (IEP) with point-of-use and portable features for on-site determination of ponceau 4R (RP), amaranth (AM), and tartrazine (TZ) in food by integrating a mass-producible Pt nanoparticles/laser-engraved graphene (Pt NPs/LEG)-based sensing chip and a reusable electrochemical miniaturized workstation. The sensing chip utilizes Pt NPs/LEG with unique architectures as electrode material and exhibits desirable analytical performance towards RP, AM, or TZ with satisfied linear range (0.25–50 μM for RP, AM, and TZ), high sensitivity (7.29 μA μM −1 cm −2 , 7.18 μA μM −1 cm −2 , and 2.02 μA μM −1 cm −2 for RP, AM, and TZ, respectively) and low limit of detection (50 nM, 58 nM, and 204 nM for RP, AM, and TZ, respectively). The sensing chip shows excellent selectivity, high stability, outstanding reproducibility, and acceptable mechanical stability. IEP can be implemented to test RP, AM, or TZ in real samples with satisfactory accuracy and recoveries.
研究领域:
分析化学
·
纳米技术
·
食品科学
·
电化学
·
传感器
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2019
·
IF 4.916
Lanqing Li,Huijun Zheng,Lili Guo,Lingbo Qu,Lanlan Yu
A special electrochemical sensor was developed based on molecularly imprinted polymer (MIP), which was formed by the dopamine (DA) self-polymerization on the surface of Pd-Cu bimetallic alloy functionalized poly (diallyldimethylammonium chloride) -dispersed graphene (PDDA-Gr). This sensor takes advantages of molecularly imprinted technique and nanocomposite to realize the application of amaranth determination with high selectivity and sensitivity. In this study, the nanocomposite PDDA-Gr-(Pd-Cu) characterized by various techniques provides large surface area and accelerates the electron transfer process. The imprinted composite deposited on the surface of PDDA-Gr-(Pd-Cu), not only provides abundant specific cavities to amaranth , but also decreases the thickness of molecularly imprinted polymer leading to high conductivity. The electrochemical behavior of amaranth on the modified electrode was studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). After optimization, the anodic peak current showed a linear relationship with the concentration of amaranth in the range of 0.006–10 μM, and the limit of detection (LOD) was 2 nM. The proposed sensor distinguished amaranth from other structurally similar substances such as sunset yellow and tartrazine with good results. In addition, the molecularly imprinted sensor proposed in this study was successfully applied to determine amaranth in the soft drink with satisfactory recoveries.
研究领域:
电分析化学
·
食品安全
·
纳米材料
·
传感器技术
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2015
·
IF 3.391
Meiling Wang,Yinlu Sun,Xiongbo Yang,Jianwei Zhao
Graphene oxide (GO) is a pH-dependent amphiphile. In this paper, it was found that carbon nanotubes (CNTs) can be highly dispersed in graphene oxide “water” with the aid of prototype ionic liquid of 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF 6 ]). The introduction of [BMIM][PF 6 ] not only can minimize the defects of poor electrical conductivity of GO, but also can improve the dispersibility of CNT in water. Hence, a new composite of CNT/GO-[BMIM][PF 6 ] with high dispersibility and strong conductivity was presented for the first time and employed in the sensitive determination of Amaranth in soft drinks. The detection limit achieved (0.1 nM) is much lower than the guideline values in soft drinks. The ease of preparation, low background current, high sensitivity and stability can create novel avenues and applications for fabricating robust sensors for determination of other azo dyes in foods.
研究领域:
分析化学
·
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）