Food Packaging and Shelf Life
·
2026
·
IF 10.8
Xin Hu,Zhen Zhang,Chen geng,Peijie Hou,Jun Wang,Yang Li,Lifang Zhang
Food spoilage driven by oxidative stress and microbial contamination remains a major challenge in minimally processed fruits, while the development of flexible biodegradable packaging systems with regulated and responsive bioactivity remains limited. In this study, a flexible bio-based active film was fabricated by incorporating gallic acid (GA) into a biodegradable poly( L -lactide)-b-poly(trimethylene carbonate) (PLLA-b-PTMC, PLT) matrix. Intermolecular hydrogen bonding between GA and PLT induced microstructural reorganization and altered chain mobility, enabling biphasic, diffusion-controlled GA release with pH-dependent behavior. The composite films exhibited reactive oxygen species scavenging activity, dose-dependent antibacterial performance against Escherichia coli and Staphylococcus aureus, and maintained cytocompatibility at effective GA loadings. Application in a fresh-fruit preservation model demonstrated delayed browning and moderated quality deterioration during storage. These findings indicate that regulating polymer–polyphenol interactions can align release behavior with storage-induced environmental changes, contributing to oxidative and microbial spoilage control in minimally processed fruits.
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Materials Today Communications
·
2025
·
IF 4.5
Peng Liu,Junpeng Mao,Lili Gao,Yaxin Gu,Yunxue Liu,Yunwu Yu,Lihua Wang
In this study, we successfully developed a novel mussel-inspired composite loose nanofiltration (LNF) membrane through a facile “one-step” membrane-forming method. The membrane was constructed by co-depositing tannic acid (TA) and polyethyleneimine (PEI) at controlled mass ratios on a polyvinylidene fluoride (PVDF) substrate, mimicking mussel adhesion chemistry. To further enhance membrane performance, we introduced a secondary modification strategy involving metal ion (M + ) coordination via dopamine (DA)-mediated cross-linking. Experimental results demonstrate that the performance of the mussel-inspired LNF membrane was significantly affected by varying the TA/PEI ratio. The T-P-P/DA-Fe 3+ membrane exhibited an impressive pure water flux of 5517.2 L/(m²·h), high dye rejection rate of 99.6 %, notably salt-dye separation selectivity (α) of 708.4, indicating great potential for application in the treatment of textile wastewater.
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FIBERS AND POLYMERS
·
2025
·
IF 2.3
Fang Chengge,Ma Ling,Chen Timson,Chen Ya,Li Zhizhen,Yan Xiaodong,Wang Jing
Metal-phenolic networks (MPNs) have been considered an alternative to the commercial hair dyes. However, it is still challenging to dye white hair black without damaging the hair because the deposition of MPNs is restricted on the surface of the healthy hair. Herein, we develop a novel damage-free strategy that not only promotes surface deposition of MPNs, but also favors internal formation of MPNs. Firstly, basic amino acids that can help open the hair cuticle penetrate into the hair. Then the numerous amino and carboxyl groups of the amino acids serve as coordination sites for Fe 2+ absorption, which facilitates the interfacial and internal growth of MPNs, thereby deepening the color of the dyed hair. As the intake of amino acids increases in the hair, the amount of Fe that enters into the hair increases to enhance the coloration. The dyed hair is capable of withstanding repeated washing with shampoo for at least 15 times without fading. Moreover, the surface MPNs bring about good resistance to UV damage, light fastness, and antioxidant properties, while the amino acids to some extent can repair the potential damage to hair.
研究领域:
材料科学
·
化学
·
化妆品科学
·
生物化学
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FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Wenyue Wang,Xuan Li,Zhongxiang Fang,Jinfeng Bi
Pectin structure plays a vital role in determining the quality of food systems. This study investigated the impact of pectin structural variations on polyphenol oxidase (PPO)-catalyzed catechin oxidation using a series of pectin fractions prepared through polygalacturonase (PG) treatment. PG progressively degraded homogalacturonan (HG) regions, reduced molecular weight, and increased the exposure of hydroxyl and carboxyl groups, thereby converting the pectin matrix from a compact to a disordered state. Among these fractions, pectin enriched in rhamnogalacturonan I (RG-I) with an extended conformation, characterized by longer RG-I chains and fewer branches, exhibited weaker interactions with PPO and catechin, resulting in disordered aggregation and the lowest catalytic efficiency. Integration with molecular docking further revealed that high-HG pectin formed compact hydrophobic networks that restricted substrate access, resulting in high Vmax but low affinity. Conversely, low-HG pectin promoted hydrogen bonding with PPO and catechin, as well as facilitated ordered aggregation. Despite a lower Vmax, it exhibited a markedly reduced Km, resulting in enhanced overall catalytic efficiency. These findings demonstrate that pectin modulates PPO-catalyzed oxidation through steric hindrance, affinity interactions, and aggregation behavior, providing new insights for controlling enzymatic browning in food systems through structural modulation of pectin.
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Food Bioscience
·
2025
·
IF 5.9
Limin Wang,Hong Yun,Yuyou Liu,Weiwei Zhang
In this study, grape seed polyphenol-copper complex (GSPCC) was successfully prepared by complexing grape seed polyphenols (GSP) with divalent copper ions. A systematic investigation was conducted on its antifungal activity and mechanism of action against Gloeophyllum trabeum and Aspergillus niger . The inhibition zone assay showed that the minimum inhibitory concentrations (MIC) of GSPCC against Gloeophyllum trabeum and Aspergillus niger were 0.078 mg/mL and 0.156 mg/mL, respectively, while the minimum fungicidal concentration (MFC) against both fungi were 0.312 mg/mL. Its antifungal activity was superior to that of GSP and copper ions alone. GSPCC increases the permeability of fungal cell membranes, leading to the leakage of intracellular nucleic acids and proteins, while significantly inhibiting the activities of cellulase and hemicellulase. Furthermore, metabolomic analysis indicated that GSPCC interferes with key metabolic pathways of fungi, including amino acid synthesis (especially inhibiting the production of L-arginine and L-glutamate), carbohydrate metabolism (disrupting the tricarboxylic acid cycle and glycolysis process), and lipid metabolism (reducing unsaturated fatty acids and decreasing membrane fluidity). This study confirms that GSPCC is an effective antifungal agent, providing a theoretical foundation for developing novel plant polyphenol-based antifungal agents.
研究领域:
微生物学
·
真菌学
·
生物无机化学
·
植物病理学
·
代谢组学
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Collagen and Leather
·
2023
·Vol. 5
·期 1
·1-13
·
IF 0
Dong Jinhong,Wang Tianyou,Li Haotian,Zhang Jianhua,Zhang Hengjie,Liu Weijie,You Xinru,Gu Zhipeng,Li Yiwen,Chen Xianchun,Fu Qiang
The development of advanced sustainable biomedical materials with superior biosafety and bioactivity for clinical applications is highly desirable. In the present investigation, biomass-based nanoparticles (NPs) were assembled through the Mannich reaction between the plant polyphenols and the broad-spectrum antibiotic tigecycline (TG). The fabricated NPs with uniform size demonstrated excellent oxidative balance effects, pH-responsive release properties and antibacterial performances. Furthermore, the intracellular and in vivo studies confirmed that the NPs are capable of reducing oxidative damage to cells and significantly repairing tissue injury in mice with peritonitis. This work presents an effective method and idea for constructing biomass-based materials for the treatment of infection-induced diseases. Graphical Abstract
研究领域:
生物医学材料
·
药理学
·
微生物学
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Shuailin Liu,Mengna Wang,Yujie Shen,Yinghui Song,Baojun Yang,Jifeng Liu,Xia Gao
OG/ICG, an intelligent nano-prodrug, is engineered by conjugating OPC with GEN, and ICG loading. • OG/ICG remains inert systemically but switches charge and dissociates in acidic infections. • The efficacy of GEN against MRSA was restored through the synergistic action of OPC and photothermia. • Combined chemical, physical, and targeting actions enable full eradication of GEN-resistant MRSA. The waning efficacy of aminoglycosides, like gentamicin (GEN), against methicillin-resistant Staphylococcus aureus (MRSA) necessitates strategies that transcend the protracted pipeline of de novo antibiotic discovery. Herein, we present a “resensitization” strategy enabled by a carrier-free, supramolecular nano-prodrug (OG/ICG NPs), engineered via the oxidative co-assembly of oligomeric proanthocyanidin (OPC) and GEN, followed by indocyanine green (ICG) loading. Distinct from conventional inert delivery systems, this bioactive platform remains stable physiologically but undergoes charge reversal and rapid dissociation within the acidic infection microenvironment. Mechanistically, the released OPC functions as a potent resistance-breaking adjuvant by disrupting cell wall integrity and inhibiting efflux pumps, thereby facilitating massive intracellular GEN accumulation. Under near-infrared (NIR) irradiation, localized hyperthermia synergizes with this chemical attack to compromise membrane permeability and trigger pronounced metabolic collapse, characterized by disrupted fatty acid degradation and ATP depletion, as revealed by both transcriptomic and phenotypic profiling. Furthermore, the nanoplatform promotes regulating macrophage polarization from M1 to M2 phenotype, accelerating abscess resolution and tissue regeneration. This work establishes a robust, dual-responsive paradigm that not only eradicates resistant pathogens through metabolic and structural disruption but also orchestrates an immune-favorable microenvironment for wound healing.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2026
·
IF 6.7
Li Enze,Xu Jingyi,Mao Xinliang,Mao Jiangyi,Mao Like
Polyphenol–saliva interactions
disrupt mucin-mediated
lubrication
and induce astringency, yet most models neglect dynamic salivary replenishment.
Here, a stepwise artificial saliva (AS) addition model was developed
to compare tannic acid (TA) and (−)-epigallocatechin gallate
(EGCG), with or without xanthan gum (XG). Four systems (TA–AS,
EGCG–AS, TA–XG–AS, EGCG–XG–AS)
underwent sequential AS replenishment and were characterized using
colloidal, spectroscopic, tribological, and electronic tongue analyses.
TA–AS progressively formed larger aggregates and exhibited
the highest friction, whereas EGCG–AS generated smaller particles
and showed lower friction at intermediate stages. In XG-containing
systems, TA–XG–AS formed ternary networks with mucin,
stabilizing lubrication and reducing astringency. EGCG–XG–AS
primarily enhanced film retention with limited aggregation. Spectroscopy
and molecular docking suggested stronger TA–mucin interactions,
whereas EGCG interactions were more reversible. Overall, polyphenol
structure and XG modulation under dynamic replenishment governed mucin
lubrication and astringency attenuation.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Jun Zeng,Gang Du,Xue Shao,Ke-Na Feng,Ying Zeng
Theaflavins (TFs) have attracted much attention due to their various bioactivities in black tea. This paper describes the first trial for enzymatic production of TFs by recombinant polyphenol oxidases (PPOs). PPO genes were cloned from nine species and expressed in E. coli . Crude enzyme assays by LC-MS revealed that eight recombinant PPOs were active for TFs production from tea polyphenols as substrates. Much higher activities were observed for crude enzymes of Md2 from Malus domestica (apple), Pp4 from Pyrus pashia (pear), and Ej2 from Eriobotrya japonica (loquat). When immobilized on mesoporous silica, crude Md2 was most active. The purified Md2 was immobilized and showed almost twice activity as high as its free enzyme. While the maximum activity of free enzyme was found at pH 5 and 10–30 °C, the immobilized enzyme had broader range of pH 4–6 and 10–40 °C. The activity of immobilized enzyme was relatively constant during the pH and thermal stability test. When used at 0.2 mg/ml in the beginning, the immobilized enzyme retained approximately 40% of its initial activity after 8 cycles of operation.
研究领域:
生物技术
·
酶学
·
食品科学
·
植物生化
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PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Xiangyang Li,Jun Yang,Mohammad Rizwan Khan,Naushad Ahmad,Wanli Zhang
To overcome the instability and rapid release of natural antimicrobial agents, a photothermal-responsive soy protein isolate (SPI) film was developed by incorporating polydopamine–tea polyphenol nanoparticles (PDA@TP NPs). PDA@TP NPs were synthesized via dopamine self-polymerization and Michael addition, achieving 86.82 % tea polyphenol (TP) encapsulation. Under 808 nm near-infrared (NIR) irradiation, the film rapidly reached 61 °C, enhancing antibacterial activity (99.2 % and 95.3 % inhibition against S. aureus and E. coli ) and enabling controlled TP release. Compared to direct TP addition, PDA@TP NPs improved thermal stability and sustained-release efficiency. The nanocomposite film exhibited enhanced tensile strength (13.5 % increase), reduced water vapor permeability (10.33 × 10 −10 g·m·m −2 ·Pa −1 ·s −1 ), and UV-blocking properties. In strawberry preservation trials, the film extended shelf life from 4 to 8 days under ambient conditions while maintaining fruit quality. This work provides a biodegradable, multifunctional packaging solution integrating photothermal antibacterial action and on-demand release for sustainable food preservation.
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Biosurface and Biotribology
·
2023
·
IF 0
Rong Hu,Xiao Wang,Lu Han,Xiong Lu
Selenium (Se), a well-known essential element in human health, plays a vital role in regulating metabolism owing to its antioxidative nature. However, organic Se compounds are toxic and cannot be used for biomedical applications. Selenium nanoparticles (SeNPs) exhibit low biological toxicity and high bioavailability; however, they are prone to aggregation and are extremely unstable, thereby diminishing their bioactivity and bioavailability. To overcome these limitations, ultra-small, highly stable, and bioactive SeNPs were synthesised based on an in-situ hybridisation strategy by using polyphenol-grafted-chitosan (GA-CS) to control and restrict crystal growth of Se nanoparticles. The resultant GA-CS@nSe exhibited an average particle size of ∼30 nm and was highly stable in aqueous solutions. In addition, GA-CS@nSe displayed improved biocompatibility and enhanced antioxidative activity. Taken together, the authors provide a basis for polyphenol-mediated construction of Se-based particles with increased bioactivity.
研究领域:
纳米技术
·
材料科学
·
生物医学工程
·
药学
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DOI
EcoMat
·
2022
·Vol. 4
·期 3
·e12173
·
IF 12.213
Yu Huyan,Jian-Gan Wang,Shan Tian,Lingbo Ren,Huanyan Liu,Bingqing Wei
Zn metals have gained the immense attention of researchers for their wide employment as the anode of high-performance aqueous batteries. Nonetheless, the Zn anodes suffer from uncontrollable dendrite growth and parasitic side reactions, which substantially shorten the battery lifespan. This study proposes an interfacial assembly of a metal-polyphenol coordination coating on Zn anodes to regulate Zn 2+ deposition behavior. Bismush-coordinated polyphenolic ligands (i.e., tannic acid, TA) create a functional interface that could promote Zn's uniform nucleation and plating/striping kinetics. Moreover, the artificial coating acts as a physical barrier to inhibit surface corrosion. As a consequence, the TA-Bi-modified Zn anodes display a small voltage hysteresis of ~38 mV at 1 mA cm −2 over 2600 h and an ultra-long lifespan for 3100 h (~4.3 months) even at a high-current density of 10 mA cm −2 . When assembled with a vanadium-based cathode, the full Zn-ion batteries achieve improved electrochemical performance.
研究领域:
材料科学
·
电化学
·
能源存储
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高影响因子
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