JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2024
·
IF 3.3
Wenxian Liu,Liting Xu,Haina Cheng,Zhu Chen,Hongbo Zhou,Yuguang Wang
BACKGROUND The potential for the efficient conversion of lignocellulosic biomass has been extensively explored to produce a wide range of bioproducts. Many approaches have been sought for the deep conversion of lignin to generate products that are toxin-free and beneficial for processing into high-value-added components. RESULTS This study reported a fungus isolated from the deep sea with strong synthesis of multiple lignocellulases, conversion of lignin and guaiacol (0.1%) by 71.6% and 86.1% within 9 days at 30 °C respectively, and outstanding environmental adaptability (20–50 °C and pH 3–8). Metabolic pathway profiling showed that this fungus utilized lignin to rapidly activate multiple ring-opening reactions including the 2,3- and 3,4-cleavage pathways, with the 2,3-cleavage pathway predominating after 5 days. Conversion of metabolic intermediates confirmed the superb potential of this strain for lignin treatment. Meanwhile, its shikimic acid pathway was metabolically active under lignin. CONCLUSION This further expands the potential to produce valuable bioproducts during lignin treatment, especially under ambient conditions, which can significantly enhance high-value precursor compound production. © 2024 Society of Chemical Industry.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Polymers
·
2024
·Vol. 16
·期 3
·405
·
IF 4.7
Xiaoyan You,Hui Liu,Yue Chen,Guoping Zhao
Liposomes show promise for anti-cancer drug delivery and tumor-targeted therapy. However, complex tumor microenvironments and the performance limitations of traditional liposomes restrict clinical translation. Hyaluronic acid (HA)-modified nanoliposomes effectively target CD44-overexpressing tumor cells. Combination therapy enhances treatment efficacy and delays drug resistance. Here, we developed paclitaxel (PTX) liposomes co-modified with ginsenoside compound K (CK) and HA using film dispersion. Compared to cholesterol (Ch), CK substantially improved encapsulation efficiency and stability. In vitro release studies revealed pH-responsive behavior, with slower release at pH 7.4 versus faster release at pH 5. In vitro cytotoxicity assays demonstrated that replacing Ch with CK in modified liposomes considerably decreased HCT-116 cell viability. Furthermore, flow cytometry and fluorescence microscopy showed a higher cellular uptake of PTX-CK-Lip-HA in CD44-high cells, reflected in the lower half maximal inhibitory concentrations. Overall, CK/HA-modified liposomes represent an innovative, targeted delivery system for enhanced tumor therapy via pH-triggered drug release and CD44 binding.Keywords:liposomes;compound K;tumor-targeted therapy;PTX;hyaluronic acid
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF PHYSICS
·
2024
·
IF 4.6
Zhuojia Xie,Zhengguang Zou,Changji Xu,Shenglin Zhong,Min Feng,Xinyu Jiang,Weijian Zhang,Xiuxin Zheng,Wenbin He
We prepared La 0.8- x K x Sr 0.2 Mn 0.95 Co 0.05 O 3 (0 ⩽ x ⩽ 0.1) (LKSMCO) through the modified sol-gel method (S-G) and its structure. Then, the magnetic, magnetocaloric, and critical behavior were analyzed. LKSMCO was confirmed to be the rhombohedral structure within the R-3c space group (No.167) using transmission electron microscopy and X-ray diffraction. For validating the chemical composition of LKSMCO, X-ray photoelectron spectroscopy and EDS were applied, showing that K + was successfully doped. Phase transition of LKSMCO from paramagnetic to ferromagnetic phase near Curie temperature (Tc) was confirmed with a Magnetic Property Measurement System (MPMS). Using normalization and Banerjee's criterion, LKSMCO was demonstrated to be the second-order magnetic phase transition (SOMPT). As shown from the applied magnetic field, the maximal magnetic entropy ( − Δ S M m a x ) of LKSMCO near Tc was 3.87 J/(kg K) ( x = 0.00), 4.28 J/(kg K) ( x = 0.05) and 4.44 J/(kg K) ( x = 0.10). We employed the Kouvel-Fisher approach (KF) and modified Arrott plots to confirm the values of γ, δ , and β . This indicates that critical exponents of LKSMCO were consistent with the Mean-filed model.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-12
·
IF 14.7
Zhang Shi-Nan,Gao Peng,Liu Qian-Yu,Zhang Zhao,Leng Bing-Liang,Chen Jie-Sheng,Li Xin-Hao
Electrochemical nitrate reduction reaction offers a sustainable and efficient pathway for ammonia synthesis. Maintaining satisfactory Faradaic efficiency for long-term nitrate reduction under ampere-level current density remains challenging due to the inevitable hydrogen evolution, particularly in pure nitrate solutions. Herein, we present the application of electron deficiency of Ru metals to boost the repelling effect of counter K + ions via the electric-field-dependent synergy of interfacial water and cations, and thus largely promote nitrate reduction reaction with a high yield and well-maintained Faradaic efficiency under ampere-level current density. The pronounced electron deficiency of Ru metals boosts the repelling effect on hydrated K + ions, as indicated by the distance of K + ions to catalyst surface, which can loosen the water layer to depress hydrogen evolution and accelerate nitrate conversion. Consequently, the optimized electrode loaded with electron-deficient Ru atomic layers can directly produce 0.26 M ammonia solution in pure nitrate solution in 6 h, providing a high yield (74.8 mg mg cat –1 h –1 ) and well-maintained the Faradaic efficiency for over 120 h under ampere-level reduction.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
·
2012
·Vol. 59
·期 11
·1415-1420
·
IF 0.678
Jinyun Peng,Keliang Nong,Lingping Cen
Acid chrome blue K (ACBK) was electropolymerized on the surface of a glassy carbon electrode (GCE) by cyclic voltammetric sweep in the potential range from –0.2 to 0.9 V. The characteristic of poly-ACBK film was studied by different methods such as electrochemical impedance spectroscopy (EIS) and cyclic voltammetry. This modified electrode showed excellent electrocatalytic response to curcumin with the increase of the electrochemical responses. Under the optimal conditions a good linear voltammetric response could be obtained over the range of 1.0 × 10 −7 -7.0 × 10 −5 M and the detection limit was got as 4.1 × 10 −8 M (S/N = 3). The method was successfully applied for the determination of curcumin in human urinev samples.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-13
·
IF 15.7
Wang Zhitong,Liu Dongyu,Xia Chenfeng,Shi Xiaodong,Zhou Yansong,Liu Qiuwen,Huang Jiangtao,Wu Haiyan,Zhu Deyu,Zhang Shuyu,Li Jing,Deng Peilin,Vasenko Andrey S.,Xia Bao Yu,Tian Xinlong
Acidic electrochemical CO 2 conversion is a promising alternative to overcome the low CO 2 utilization. However, over-reliance on highly concentrated K + to inhibit the hydrogen evolution reaction also causes (bi)carbonate precipitation to interfere with catalytic performance. In this work, under the screening and guidance of computational simulations, we present a carbon coated tip-like In 2 O 3 electrocatalyst for stable and efficient acidic CO 2 conversion to synthesize formic acid (HCOOH) with low K + concentration. The carbon layer protects the oxidized In species with higher intrinsic activity from reductive corrosion, and also peripherally formulates a tip-induced electric field to regulate the adverse H + attraction and desirable K + enrichment. In an acidic electrolyte at pH 0.94, only 0.1 M low K + is required to achieve a Faradaic efficiency (FE) of 98.9% at 300 mA cm −2 for HCOOH and a long-time stability of over100 h. By up-scaling the electrode into a 25 cm 2 electrolyzer setup, a total current of 7 A is recorded to sustain a durable HCOOH production of 291.6 mmol L −1 h −1 .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENERGY & FUELS
·
2025
·
IF 5.3
Fang Wang,Xueyan Wu,Yuxuan Han,Yan Lv,Jixi Guo,Xiaoman Li,Yaping Zhang
In cement kiln flue gas emissions, high concentrations of alkali and alkaline earth metals cause the deactivation of the NbCe/Ti catalysts, significantly reducing their operational lifespan under industrial conditions. Here, the NbCe-loaded titanium nanotubes (NbCe/TiNTs) catalyst has been synthesized via hydrothermal and impregnation methods. The NbCe/TiNTs catalyst exhibits superior resistance to potassium (K) and calcium (Ca) poisoning. Notably, NbCe/TiNTs catalyst maintains high NOx conversion across a wide temperature range (192–350 °C). The 5Ca-NbCe/TiNTs and 3K-NbCe/TiNTs catalysts achieve a 90% NOx conversion at 235 and 242 °C, respectively, demonstrating remarkable resistance to K and Ca poisoning. The results indicate that TiNTs supports enhance both the specific surface area and surface acid sites of the catalyst, synergistically improving its resistance to K and Ca poisoning. Furthermore, an in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) study elucidates selective catalytic reduction with the NH3 (NH3-SCR) reaction mechanism, revealing dual contributions from both the Eley–Rideal (E–R) and Langmuir–Hinshelwood (L–H) mechanisms on the catalyst. This work provides a research direction for enhancing the alkali poisoning resistance of NOx removal catalysts.
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2025
·
IF 12.1
Qiankun Zhang,Zhewen Ma,Haimin Zhang,Xuan Lan,Zongkun Bian,Yongchun Luo
This study puts forward an innovative electrolyte design to resolve the problems of scarce efficient proton sources and interface instability in proton batteries. It verifies that hydrogen protons mainly come from water molecule dissociation, with acetic acid acting as an auxiliary source, leading to proton source concentration changes during charging/discharging. To address this, an ionic liquid (1-Ethyl-3-methylimidazolium acetate, abbreviated as [emim][Ac]) electrolyte containing acetic acid (HAc) and potassium acetate (KAc) ([emim][Ac] + 4 m HAc + 1 m KAc) is developed. Experimental results show the battery performs excellently, with a discharge capacity up to 1584 mAh g −1 , and retains 1217 mAh g −1 at a 6000 mA g −1 discharge current density after 300 cycles. Both experiments and simulations confirm H⁺ primarily comes from HAc and H 2 O solvated by K⁺ and imidazolium cations. K⁺ introduces a new “vehicle transport channel” to reduce proton transport resistance, while HAc and KAc form a buffer solution to optimize solvation structure and inhibit side reactions. Ionic liquids provide a stable environment for ion transport. This work offers references for developing high-rate, long-cycle proton batteries.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RARE METALS
·
2025
·
IF 11
Long Xia,Liu Xiao-Chi,Yang Yan-Yi,Dai Jia-Qing,Cao Jue-Xian,Hu Yong
Gaining insights into charge transport related to conformational changes and ion transport in valinomycin (VM) is crucial for understanding the underlying physiological processes and advancing ion carrier applications. Observing these processes in single molecules provides deeper insights and precision than those obtained through conventional ensemble measurements. Herein, we employed a single-molecule conductance measurement method based on the scanning tunneling microscopy break-junction (STM-BJ) to measure the charge transport of individual VM molecules in both non-polar and polar solvents, as well as when mediated by K + ions. Single-molecule conductance measurements revealed that the bracelet and propeller-type conformations of VM in both non-polar and polar solvents significantly affect its conductance. In polar solvents, the propeller-type conformation of VM demonstrated a well-defined conductance signature, single-molecule rectification feature, and through-space transmission mechanism. Specifically, the introduction of K + ions in polar solvents induced a conformational transition from the propeller-type to the bracelet-type form, facilitating K + binding recognition. These observations were further supported by density functional theory combined with non-equilibrium Green’s function calculations. This study enhanced the fundamental understanding of the electronic transport mechanisms in VM and valinomycin-K + molecular junctions, offering insights into VM ionophores and promoting supramolecular sensing applications. Graphical abstract
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-9
·
IF 14.7
Chen Donglin,Sha Juncheng,Mei Xudong,Ye An,Zhao Zhengping,Qiu Xunlin,Liu Xiaoyun,Niu Yueping,Zuo Peiyuan,Zhuang Qixin
As integrated circuits have developed towards the direction of complexity and miniaturization, there is an urgent need for low dielectric constant materials to effectively realize high-fidelity signal transmission. However, there remains a challenge to achieve ultralow dielectric constant and ultralow dielectric loss over a wide temperature range, not to mention having excellent thermal conductivity and processability concurrently. We herein prepare dual-linker freestanding covalent organic framework films with tailorable fluorine content via interfacial polymerization. The covalent organic framework possesses an ultralow dielectric constant (1.25 at 1 kHz, ≈1.2 at 6 G band), ultralow dielectric loss (0.0015 at 1 kHz) with a thermal conductivity of 0.48 Wm −1 K −1 . We show high-fidelity signal transmission based on the large-sized (>15 cm 2 ) COF films, far exceeding the most commercially available polyimide-based printed circuit board. In addition, the covalent organic framework also features excellent electret properties, which allows for active high-temperature electromechanical sensing. The electrode nanogenerator maintains 90% of the output voltage at 120 °C, outperforming the traditional fluorinated ethylene propylene electret. Collectively, this work paves the way for scalable application of ultralow dielectric constant covalent organic framework thin films in signal transmission and electromechanical sensing.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemistry-Switzerland
·
2025
·Vol. 7
·期 5
·150
·
IF 2.4
Ting Geng,Yuhan Qin,Zhuo Chen,Yuhan Sun,Ao Zhang,Mengyuan Lu,Mengzhen Lu,Siying Zhou,Yongguang Li,Guanjun Xiao
Lead-free perovskite variants have emerged as promising candidates due to their self-trapped exciton emission. However, in ASnX3systems, facile oxidation of Sn(II) to Sn(IV) yields A2SnCl6vacancy-ordered derivatives. Paradoxically, despite possessing a direct bandgap, these variants exhibit diminished photoluminescence (PL). Doping engineering thus becomes essential for precise optical tailoring of A2SnX6materials. Herein, through integrated first-principles calculations and spectroscopic analysis, we elucidate the luminescence mechanism in Te4+-doped (NH4)2SnCl6lead-free perovskites. Density functional theory, X-ray diffraction (XRD) patterns and X-ray photoelectron spectroscopy (XPS) confirm Te4+substitution at Sn sites via favorable chemical potentials. Spectral interrogations, including absorption and emission profiles, reveal that the intense emission originates from the triplet STE recombination (3P1→1S0) of Te centers. Temperature-dependent PL spectra further demonstrate strong electron–phonon coupling that induces symmetry-breaking distortions to stabilize STEs. Complementary electronic band structure and molecular orbital calculations unveil the underlying photophysical pathway. Leveraging these distinct thermal responses of PL intensity and peak position, 0.5%Te:(NH4)2SnCl6emerges as a highly promising candidate for non-contact, dual-parameter optical thermometry over an ultra-broad range (100–400 K). This work provides fundamental insights into the exciton dynamics and thermal engineering of optical properties in this material system, establishing its significant potential for advanced temperature-sensing applications.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Jianghua Wu,Faisal Faiz,Mashkoor Ahmad,Miao Zhengjie,Zha Qiang,Wei Xu,Xiaojin Zhao,Xiaofang Pan,Yasir Faiz
The fabrication of supercapacitors with outstanding performance is presented with a distinct defect-rich nanostructures. A one-pot, energy-efficient method for synthesizing defective manganese dioxide nanowires doped with potassium (K 0.35 MnO 2 ) was developed. The introduction of potassium ions at 35 % birnessite resulted in a significant increase in lattice defects and an improvement in conductivity. Addition of KOH induces a phase transition from α-MnO 2 to δ-MnO 2 . These imperfections result in a greater quantity of active sites, which are crucial for the process of energy storage. The K 0.35 MnO 2 structure demonstrates a 405F/g increased capacity at a current density of 1 A/g. The asymmetric supercapacitor (K 0.35 MnO 2 /AC) that was manufactured exhibits a capacitance of 106.4F/g when operating at 1 A/g, while maintaining a maximum energy density of 71.5 Wh kg −1 and a power density of 672 W kg −1 . Furthermore, 92.7 % of the initial capacitance of the device is retained even after 8,000 cycles at 20 A/g. This study presents novel insights into the production of defective materials for energy storage applications through the utilization of a one-pot process as opposed to the multi-step method. In order to produce high-performance supercapacitors for practical applications, the results indicate that defect engineering is a crucial factor.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）