Micromachines
·
2023
·Vol. 14
·期 10
·1896
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IF 3.4
Zhou Yao,Libing Zhang,Ting Wu,Haijun Song,Chengli Tang
Metal–organic frameworks (MOFs) have broad potential applications in electrochemical glucose detection. Herein, a green ultrasonic synthesis process is presented for preparing two-dimensional (2D) copper–nickel metal–organic framework nanosheets (CuNi-MOFNs) for glucose detection. The synthesized CuNi-MOFNs were characterized using scanning electron microscopy (SEM), scanning transmission electron microscope (STEM), X-ray diffractometer (XRD), and X-ray photoelectron spectrometer (XPS). The CuNi-MOFN nanocomposites were used to cover the glassy carbon electrode (GCE) and the CuNi-MOFNs-modified electrode was studied in alkaline media. Cyclic voltammetry (CV) and amperometric i–t curves indicated that the CuNi-MOFNs-modified electrode revealed great electrochemical performances towards glucose oxidation. Due to the ease of access to active metal sites in large specific surface of nanosheets, the CuNi-MOFNs-modified electrode can effectively improve the electronic transfer rate and enhance electrocatalytic activity of the CuNi-MOFNs-modified electrode. The CuNi-MOFNs-modified electrode showed electrochemical performances for glucose detection with a linear range from 0.01 mM to 4 mM, sensitivity of 702 μAmM−1cm−2, and detection limit of 3.33 μΜ (S/N = 3). The CuNi-MOFNs-modified electrode exhibited excellent anti-interference ability and high selectivity in glucose measurements. Hence, the CuNi-MOFNs-modified electrode has good, promising prospects in non-enzymatic electrochemical glucose detection.Keywords:metal–organic frameworks;copper/nickel nanosheets;non-enzymatic;electrochemical detection;glucose detection
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Food Science and Human Wellness
·
2023
·
IF 7
Xin Wang,Chengyi Hong,Zhengzhong Lin,Zhiyong Huang
A ratiometric fluorescent probe for hypoxanthine (Hx) detection was established based on the mimic enzyme and fluorescence characteristics of cobalt-doped graphite-phase carbon nitride (Co doped g-C 3 N 4 ). In addition to emitting strong fluorescence, the peroxidase activity of Co doped g-C 3 N 4 can catalyze the reaction of O -phenylenediamine and H 2 O 2 to produce diallyl phthalate which can emit yellow fluorescence at 570 nm. Through the decomposition of Hx by xanthine oxidase, Hx can be indirectly detected by the generating hydrogen peroxide based on the measurement of fluorescent ratio I ( F 570 /F 370 ). The linear range was 1.70–272.2 mg/kg ( R 2 = 0.997), and the detection limit was 1.52 mg/kg (3 σ / K , n = 9). The established method was applied to Hx detection in bass, grass carp, and shrimp, and the data were verified by HPLC. The result shows that the established probe is sensitive, accurate, and reliable, and can be used for Hx detection in aquatic products.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Guangli Li,Xiaoman Qi,Jingtao Wu,Xuan Wan,Tianyu Wang,Ying Liu,Yuwei Chen,Yonghui Xia
The overuse of pefloxacin (PEF) leaves residues in foods. Therefore, the development of robust analytical techniques for the selective detection of PEF is of great importance. In this study, a highly stable electrochemical sensing platform has been constructed, using molecularly imprinted polymer (MIP)-coated gold nanoparticle/black phosphorus nanocomposites (BPNS-AuNPs), for the selective detection of PEF. BPNS-AuNPs significantly enhance the black phosphorus (BP) stability and electrochemical activity and offer a larger surface area to accommodate more imprinted sites for selective PEF binding. MIP/BPNS-AuNPs exhibit a broad linear detection range (0.005–10 μM), low detection limit (0.80 nM), and high sensitivity (3.199 μA μM −1 ). The MIP/BPNS-AuNPs show a high binding affinity for PEF, even in the presence of structural analogs, and maintain stable voltammetric signals for at least 35 d. The MIP sensor exhibits consistent high sensitivity in the detection of PEF in real milk and orange juice samples.
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International Journal of Electrochemical Science
·
2023
·
IF 1.5
Mingjing Yin,Shanshan Liu,Xinying Ma,Xiangyan Meng,Mingyong Chao
Eugenol, an active substance widely used in the medical, food, and cosmetic industries, has garnered increasing attention due to its potential adverse effects on human health resulting from excessive use. In this study, a sensitive sensor for the determination of eugenol was developed by electropolymerizing γ-aminobutyric acid ( g ABA) onto the surface of a glassy carbon electrode (GCE). Experiments showed that the poly γ-aminobutyric acid ( pg ABA) membrane exhibited excellent electrocatalytic activity for the oxidation of eugenol, and its oxidation peak current was greatly increased. Under optimized conditions, the oxidation peak current of eugenol was linearly proportional to its concentration in a range of 0.6–100 μmol/L, with a correlation coefficient of 0.9985 and a detection limit of 0.2 μmol/L. The sensor’s ability to detect eugenol in various authentic samples, with recovery rates ranging from 98.0 % to 101.3 %, attests to its great potential for practical application.
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ACS Applied Polymer Materials
·
2023
·
IF 5
Lingyi Li,Shusheng Li,Hongyan Cui,Xiaoli Zhu,Xiang Zheng Kong
In recent years, multiresponsive polymers with nonconjugated chromophores featuring cluster-triggered emission (CTE) have attracted significant attention due to their wide applications and interests in fundamental studies. There is a lack of studies correlating the fluorescent properties to their distinct stimuli-responsiveness although CTE materials have been well studied. Herein, we introduced a poly(ethylene glycol)-polysiloxane copolymer, PEG-Si, which exhibits responsiveness to temperature, pH, CO2, and salinity, with adjustable phase transition and reversible fluorescence. PEG-Si was synthesized by a catalyst-free aza-Michael addition of PEG diacrylate with bis(3-aminopropyl)-tetramethyldisiloxane in dichloromethane. The structure of PEG-Si was characterized using various spectroscopic methods such as NMR and Fourier transform infrared spectroscopy (FTIR). The light transmittance and fluorescence performance of PEG-Si were measured at different temperatures under varying conditions, including polymer composition, concentration, pH, and bubbled CO2, to observe their evolution. The relationship between fluorescence properties and the phase transition process was described. The results demonstrate that PEG-Si can be used as a temperature and pH fluorescence thermometer and biosensor for detection of uric acid with a detection limit of 1.02 μmol/L. This study proposes a practical strategy for designing multiresponsive polymers with CTE features and provides significant insights into the correlation between stimuli-responsiveness and fluorescent properties, which contributes to the development of advanced materials with diverse applications.
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Scientific African
·
2023
·
IF 2.9
Yideneku Feye,Abebe Diro,Getu Sisay,Shimeles Addisu Kitte
This study was aimed to investigate the selective electrochemical determination for dopamine based on thioglyolic acid-modified gold electrode. Negatively charged Au electrode surface was created by making Thioglycolic acid film through thiol functional group. Greater oxidation current and less overpotential was observed for the oxidation of dopamine in phosphate buffer solution of pH 8.0 at thioglyolic acid-modified gold electrode than bare Au electrode due to the electrostatic attraction between the negatively charged thioglyolic acid-modified gold electrode surface and positively charged dopamine. The electrochemical behavior of dopamine at the thioglyolic acid-modified gold electrode showed a linear response from 0.05 to 100.0 µM and the limit of detection is 0.01 µM using chronoamperommetry. The proposed thioglyolic acid-modified gold electrode shows good repeatability and promising application in dopamine hydrochloride injection sample.
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MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 10
·1-7
·
IF 5.7
Quan Changyun,Chen Wenxuan,Yang Minghui,Hou Yi
An electrochemical sensor for the detection of uric acid was constructed using cobalt oxide-modified porous carbon@multi-walled carbon nanotube (MWCNTs) composite material for the modification of the electrode. Firstly, ZIF-67 is generated on carbon nanotubes using the surfactant cetylammonium bromide (CTAB) as template. The vesicles generated by CTAB act as nucleation sites for the in situ growth of ZIF-67. Then, cobalt oxide-modified porous carbon was obtained after high-temperature carbonization of ZIF-67, leading to the formation of cobalt oxide-modified porous carbon@MWCNT composite materials. Co-N and Co-O active sites on the composite material can improve the oxidation of uric acid on the electrode surface, leading to enhanced sensitivity and selectivity for uric acid detection. The sensor has a good linear range from 1 to 40 μM for uric acid detection with a detection limit of 0.09 μM. The sensor was utilized for determination of uric acid in actual serum samples. Graphical abstract
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MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Wei Zhang,Liling Zhang,Shengmiao Sun,Bixuan Wang,Ling Jiang,Liying Zhu
Dopamine (DA) dysfunction is known to cause neurological and physiological disorders, such as schizophrenia, Parkinson's disease, and addictive behavior. Therefore, dopamine detection is essential for both diagnosis and disease prevention. In this study, a novel and effective electrochemical sensor was fabricated based on a carbon quantum dots (CQDs)@molecularly imprinted polymers (MIPs) modified electrode for dopamine detection. The CQDs were obtained by an eco-friendly hydrothermal carbonization method, using sycamore leaves as a natural carbon source. The structure of the prepared CQDs@MIPs composite was confirmed through techniques including Ultraviolet–visible absorption spectroscopy, dynamic light scattering technique, scanning electron microscopy, and transmission electron microscopy. By combining the rapid electron transfer rate of the CQDs with the selective activity of the MIPs , the prepared CQDs@MIPs composite-modified electrode demonstrated greatly enhanced electrochemical performance. The developed sensor exhibited a good response towards dopamine detection, with a considerably lower detection limit (5 × 10 −9 M ) and a wider linear range (5 × 10 −9 –5 × 10 −4 M ) compared to current publications. In addition to the outstanding reproducibility and anti-interference ability, this ‘green sourced’ sensor showed great potential for practical applications, as validated by the satisfactory recovery analysis of dopamine from goat blood serum.
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CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Yutong Shen,Shanshan Chai,Qingling Zhang,Mengdi Zhang,Xue Mao,Liang Wei,Fenglei Zhou,Runjun Sun,Chengkun Liu
The detection of lactate and other bioactive molecules is of great significance in biological research, medical testing, and environmental monitoring. Organic electrochemical transistors are a kind of biosensor devices, which can convert biological signals into electrical signals. In recent years, fiber-based organic electrochemical transistors (FECTs) provide a new approach for the construction of flexible wearable biosensors, promoting greatly the development of flexible wearable electronic products. In this study, a multilayer composite electrode was first prepared by incorporating MXene and PEDOT:PSS onto electrospun oriented polyvinyl formal (PVF) nanofiber bundle, and then assembled into FECT with high sensitivity and selectivity . Meanwhile, a wearable real-time monitoring platform was built to detect the lactate concentrations in human sweat. The results showed that MXene could act as a bridge between PEDOT:PSS and PVF, and the sensing performance of PVF/MXene/PEDOT:PSS-based FECT was enhanced obviously. It had a wide linear response range of 1 nM-100 mM, a sensitivity of 0.442 NCR/decade, a quick response time of 0.5 s, a low detection concentration, an excellent reproducibility, and a superior anti-interference characteristic. Therefore, this work provided more possibilities for the development of wearable biosensor.
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CHINESE JOURNAL OF CHEMISTRY
·
2023
·Vol. 41
·期 24
·3677-3683
·
IF 5.4
Jingwen Zhao,Junchen Wang,Linggao Zeng,Sen Zhou,Xiaoming Yang
Comprehensive Summary Long-wavelength fluorescence carbon dots (CDs) show great importance in multiple fields, especially for the biochemical sensing. Here, we proposed one type of CDs doped with nitrogen and sulfur through the hydrothermal method, which exhibited obvious yellow-fluorescence in aqueous solution. Importantly, the fluorescence intensity of CDs decreased with pH decreasing in the acidic range, thus a linear relationship between pH and fluorescence intensity was established, exhibiting the potential of pH sensing. Additionally, introducing tigecycline into CDs resulted in their decreased fluorescence, thus, we further established a strategy of detecting tigecycline with the concentration range of 200 μM to 7 nM. Meanwhile, we elucidated the static quenching as the major mechanism for CDs responding tigecycline, which was induced by the formed new complex between CDs and tigecycline. Furthermore, the practicality of the method was verified by examining the recovery of tigecycline in the actual lake-water samples.
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JOURNAL OF MATERIALS SCIENCE
·
2023
·Vol. 58
·期 35
·13957-13973
·
IF 4.5
Xu Kaizheng,Ma Yingyi,Yao Shun,Liu Xiaoting
The fabrication and functionalization of three-dimensional (3D) MXene are vital for diverse high-performance applications. Herein, the construction of 3D porous MXene architecture and its functionalization with graphene are synchronously implemented by breath figure method. 3D porous rGO/MXene with multi-scale pores is prepared by simply casting the mixture of GO/surfactant and MXene/surfactant solution under humid environment and the subsequent reduction process. The aggregation inhibition of GO and MXene nanosheets at multi-scale caused by surfactant intercalation and the formation of 3D porous structure, as well as the increase in surface area induced by the introduction of GO, enlarged lamellar spacing and multi-scale porous structure endow porous rGO/MXene with excellent electrochemical performance. The synergy of rGO and MXene leads to further improvement in electrochemical property and its stability. Low detection limit, good anti-interference, repeatability, reproducibility, long-range stability and accuracy of actual sample testing are exhibited when porous rGO/MXene is used for electrochemical detection of DA. Furthermore, the electrochemical performance could be controlled via tuning the porous structure and ratio of GO and MXene. This study not only demonstrates the superiority of porous rGO/MXene toward electrochemical sensing, but also proposes a simple and universal method for controllable construction and functionalization of 3D MXene architecture. Graphical Abstract
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Analytical Methods
·
2023
·Vol. 15
·期 39
·5139-5145
·
IF 3.1
Shuting Zhang,Cuili Li,Zhihong Sun,Jie Liu,Guanglei Fu
Prussian blue (PB) is a typical peroxidase mimic with simple preparation, low cost and high eco-friendliness, but it still has drawbacks of poor stability (e.g., decomposition in aqueous dispersions) and intrinsic optical interference (e.g., high extinction coefficient over a wide wavelength range) in colorimetric assays. Herein, we used nitrocellulose (NC) membranes as synthesis hosts of PB nanoparticles (NPs) to develop a new type of three-dimensional (3D) porous nanozyme pad. By means of an in situ synthesis route, PB NPs were uniformly grown on the surfaces of the fiber scaffolds with desirable stability, which also avoided signal interference from PB NPs owing to the easy handling of the pads in a quantitative solid state. The pads showed significant peroxidase-mimicking activity toward the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) with the output of colorimetric signals. Based on the reduction of oxidized TMB (oxTMB) by dopamine (DA), the pads were exploited for simple and quantitative colorimetric detection of DA with a limit of detection (LOD) of 0.59 μM and a satisfactory accuracy for analysis of real human urine samples. This is the first attempt at exploiting NC membranes as the synthesis hosts to develop nanozyme pads, which solves the above drawbacks of traditional PB-based peroxidase mimics and has promise for various colorimetric bioanalyses, given the structural benefits of NC membranes and their broad applications in biosensors.
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