MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Adil Emin,Afei Ding,Salamat Ali,Muhammad Chhattal,Shafqat Ali,Anand Parkash,Qiang Li
In this work, an electrochemical non-enzymatic glucose sensor consisting of di-methanethiol-grafted poly (3,4-propylenedioxythiophene), gold nanoparticles (Au NPs), and reduced graphene oxide (rGO) was synthesized by a one-step method through Au-S chemisorption. The structure and morphology of the as-prepared poly (ProDOT-(MeSH) 2 )/Au/rGO composite were characterized by fourier transform infrared spectrometer (FT-IR), X-ray diffraction (XRD), energy-dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). The electrochemical performance of the composite was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) on glassy carbon electrode (GCE). The results show that because of the hydrogen bond interaction between the thiol group on the polymer units and the functional groups on GO, poly (ProDOT-(MeSH) 2 )/Au/rGO was successfully prepared. In addition, due to the unique morphological structure of the composite and the ability to absorb glucose molecules through hydrogen bonds, the poly(ProDOT-(MeSH) 2 )/Au/rGO electrode possesses excellent selectivity and unique sensitivity (46.13 μA mM −1 cm −2 ) for sensing glucose in the linear range of 0.04–16.0 mM with a detection limit of (S/N = 3) 0.01. This paper demonstrates that the poly(ProDOT-(MeSH) 2 )/Au/rGO composite holds great promise for application as a new glucose sensor in life science.
✓ 已验证
产品关联
DOI
高影响因子
Journal of the American Chemical Society
·
2024
·
IF 14.4
Yu-Qi Wang,Jiaju Fu,Yue Feng,Kaiyue Zhao,Lu Wang,Ji-Yuan Cai,Xiang Wang,Ting Chen,Fan Yang,Jin-Song Hu,Bingjun Xu,Dong Wang,Li-Jun Wan
The activity of the electrocatalytic CO2 reduction reaction (CO2RR) is substantially affected by alkali metal cations (AM+) in electrolytes, yet the underlying mechanism is still controversial. Here, we employed electrochemical scanning tunneling microscopy and in situ observed Au(111) surface roughening in AM+ electrolytes during cathodic polarization. The roughened surface is highly active for catalyzing the CO2RR due to the formation of surface low-coordinated Au atoms. The critical potential for surface roughening follows the order Cs+ > Rb+ > K+ > Na+ > Li+, and the surface proportion of roughened area decreases in the order of Cs+ > Rb+ > K+ > Na+ > Li+. Electrochemical CO2RR measurements demonstrate that the catalytic activity strongly correlates with the surface roughness. Furthermore, we found that AM+ is critical for surface roughening to occur. The results unveil the unrecognized effect of AM+ on the surface structural evolution and elucidate that the AM+-induced formation of surface high-activity sites contributes to the enhanced CO2RR in large AM+ electrolytes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Yunzhu Xu,Dahai Hou,Min Zhao,Tong Zhao,Yong Ma,Yafeng Zhang,Yang Guo,Weiwei Tao,Hui Wang
The construction of highly catalytic nanozymes that are composed of biomolecules remains a difficulty due to complicated synthesis methods and poor catalytic efficiencies. In this study, the authors fabricated noble metal ion supramolecular nanospheres (Fmoc-His-Au) through the combination of electrostatic adsorption and multifarious weak intermolecular force between AuCl4– and amphipathic histidine. The synthesis procedure is extremely simple and easy, and the noncovalent bond interactions between amphiphilic histidine and AuCl4– facilitated the constitution of supramolecular nanostructures and simultaneously stabilized the highly active AuCl4– center, which exhibited great peroxidase (POD)- and oxidase (OXD)-like capacities that could efficaciously transform the dissolved oxygen and H2O2 to reactive oxygen species (ROS). In addition, this simple and innovative nanozyme displayed a preeminent antibacterial and wound healing performance both for Staphylococcus aureus and Escherichia coli bacteria in vitro and in vivo, with the bacteria inhibition percentage of over 98% for S. aureus and E. coli, and exhibited benign biocompatibility and low toxicity. This study paves the way for designing outstanding catalytic enzyme-like supramolecular nanostructures composed of simple amino acids and metal ions for wide nanomedical and pharmaceutical applications.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Bing zhang,Yu-lian Li,Li Wang,Haoyuan Cai
Conventional surface plasmon resonance (SPR) sensor often fails to detect low-concentration small molecules due to insufficient refractive index changes. To address this challenge, we have developed an enhanced SPR sensor utilizing Fe 3 O 4 @Au@polydopamine (PDA) core–shell magnetic nanoparticles as signal amplification tags for the detection of tebuconazole (TBZ). These nanoparticles improve sensitivity through their high refractive indices and enable TBZ enrichment from complex matrices via their magnetic properties. The sensor surface is further modified with PDA, which acts as a reducing agent for Au nanoparticle deposition, enhancing monoclonal antibody (Ab) immobilization and boosting the SPR signal. Our optimized sensor reaches a limit of detection (LOD) at 0.61 ng/mL for TBZ, with a linear response from 1-200 ng/mL, and demonstrates high selectivity and reproducibility, ideal for pesticide monitoring in food samples.
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2010
·
IF 2.6
Chunyuan Song,Zhuyuan Wang,Jing Yang,Ruohu Zhang,Yiping Cui
A detailed method for preparation of 2-mercaptobenzothiazole (MBT)-labeled immuno-Au aggregates as a novel Raman probe for SERS-based immunoassay has been proposed in this paper. The formation kinetics of gold aggregates induced by MBT and the impact of the amount of labeled reporter on the aggregation, as well as the fabrication of MBT-labeled immuno-Au aggregates were characterized comprehensively by UV–vis spectrophotometer . Meanwhile, a chain-like morphology of aggregates was monitored by TEM images. Experimental results show that this Raman tag can act as an efficient label and an enhanced Raman signal of SERS-based immunoassay can be obtained successfully with this novel probe. This work shows the method for the preparation of immune probe for SERS-based immunoassay using MBT as reporter and provides a reference for the preparation of immune probe with other Raman markers for multi-channel SERS-based immunoassay.
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Xiang Zhang,Yurui Xu,Wanyao Chen,Laiyou Wang,Xinghai Ning,Haixiong Ge
UV-nanoimprint lithography (UV-NIL) has been proved to be an efficient method for preparing nanodrug delivery systems. Herein, we used UV-NIL associated with the glancing angle deposition (GLAD) process of electron beam evaporation to prepare Au-coated PLGA nanocylinders loaded with PTX (PTX-PLGA-Au NCs) to enhance anticancer efficacy by the cooperative treatment of photothermal-chemotherapy. PTX-PLGA-Au NCs with different length-to-diameter ratios can be prepared by controlling the concentration of PLGA and regulating the angle of GLAD. Upon 808 nm near-infrared (NIR) irradiation, PTX-PLGA-Au NCs exhibit a stable and repeatable photothermal effect. Besides, hyperthermia generated by the Au layer on the surface of PTX-PLGA-Au NCs under laser irradiation promoted the rapid release of PTX. The in vitro studies demonstrated that PTX-PLGA-Au NCs can achieve the synergistic effect of photothermal-chemotherapy, leading to increased cell cytotoxicity. Therefore, UV-NIL combined with the GLAD process produced a promising nanofabrication method for efficiently developing a multifunctional nanoplatform for cancer treatment.
✓ 已验证
产品关联
DOI
高影响因子
OPTICS AND LASER TECHNOLOGY
·
2024
·
IF 4.6
Hua-Long Du,Nuerguli Kari,Ben Li,Qi Wang
The fiber Surface plasmon resonance (SPR) sensor based on titanium dioxide(TiO 2 ) and Au nanoparticles (Au-NPs) sensitization is offered as a practical means of increasing the sensitivity and figure of merit (FOM). Through finite element simulation and experimental testing, it is found that in TiO 2 with high dielectric constant and high dielectric conductivity, the carrier movement is fast and consumption is low, which enhances the photocurrent signal and leads to charge redistribution, thus enhances the electric field; while the Au-NPs will stimulate the stronger Localized Surface plasmon resonance (LSPR) phenomenon, and both of them will undergo electric field resonance coupling. The sensitivity of the sensor is higher because its surface electric field is 3.67 times stronger than the conventional Au film sensor. When exposed to external conditions, the sensitivity can reach 9715 nm/RIU within the refractive index (RI) at 1.33213–1.34055, which is 4.69 times higher than a conventional Au film sensor. The FOM can reach 57.8 RIU -1 , which is 2.05 times higher than the conventional Au film sensor. In addition, TiO 2 and Au-NPs on the surface of the sensor are less prone to collapse, and the stability test results show that the relative standard deviation (RSD) is 0.5929 %, which exhibits good reliability and stability. The structure of the sensor is very simple, relatively easy to fabricate, and has good applicability in the field of biochemical testing.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Xiangqian Kong,Wenyan Xia,Yuruo Qiu,Bingrui Zhao,Yuan Zhao,Wei Ma
Polystyrene (PS) plastics were potentially present in consumer products through the use of plastics packaging. The migration and enduring presence for bioaccumulation posed significant threats to human health and the environment. It was significant to develop a simple and reliable approach for sensitive PS plastics detection. In this study, Au-Bi 2 Se 3 hybrid nanosheets (NSs) were designed and utilized as SERS probes for the detection of PS plastics. The electron transfer from Bi 2 Se 3 to AuCl 4 − induced the formation of Au NPs on the surface of thin Bi 2 Se 3 NSs. Au-Bi 2 Se 3 hybrid NSs were found to display enhanced SERS activity by using PS plastics as Raman tags. Besides the unique electromagnetic enhanced mechanism from Au NPs, the introduction of Bi 2 Se 3 supported the Dirac plasmon polaritons in electromagnetic modes, and Bi 2 Se 3 with high dielectric constants inhibited the decay of electromagnetic waves. Au-Bi 2 Se 3 hybrid NSs engineered SERS sensor achieved stable and sensitive detection of PS plastics in essence liquid. Different sized PS plastics ranging from 89.3 nm to 1.48 μm were detected with the LODs of ppm levels. These findings highlight the potential of Au-Bi 2 Se 3 hybrid NSs as effective and universal SERS substrates for detecting different sized plastics in real samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Jianglin Tu,Jun Zhang,Hao Song,Xun Zhu,Dingding Ye,Yang Yang,Xiao Yan,Hong Wang,Rong Chen,Qiang Liao
The utilization of crude glycerol, a byproduct of biodiesel, for hydrogen production is a promising approach to recover waste into clean energy. In this study, we develop a novel dual-nanostructured plasmonic Au-NS&NR/TiO 2 by co-loading Au nanorods (Au NR) and nanospheres (Au NS) onto TiO 2 for photothermal catalytic hydrogen production in the presence of glycerol. It is demonstrated that the coupling between the resonant wavelengths of Au nanospheres and nanorods broadens the light response range. The stronger localized electromagnetic field generated by the Au nanorods facilitates the generation of photogenerated charge carriers, while the Au nanospheres enable more efficient utilization of hot electrons. The thermal effect induced by localized surface plasmon resonance enhances molecular collisions, further improving the photothermal catalytic hydrogen production performance. This work highlights the potential application of photothermal catalytic hydrogen production using solar energy in the presence of glycerol.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-16
·
IF 15.7
Zhang Zekun,Guo Hua,Li Shiji,Gao Suihan,Wang Xinyu,Li Mingtao,Yan Wei,Xu Hao
The regulation of product selectivity in electrochemical CO 2 reduction (ECO 2 R) remains fundamentally constrained by the dynamic equilibrium between intermediate transport and surface coverage. In this study, we report a progress in catalytic architecture through precision-engineered Au@Cu 2 O yolk-shell tandem nanoreactors featuring dual-tunable parameters: cavity confinement dimensions and shell thickness gradients. This structural modulation enables dynamic control over both *CO intermediate enrichment and reaction pathway bifurcation. ECO 2 R performance evaluations demonstrate significant product selectivity switching at −1.31 V (vs. reversible hydrogen electrode (RHE)). The Faradaic efficiency (FE) for CH 4 exhibits significant architectural dependence, increasing from 43.02% (thick-shell/large-cavity) to 65.54% (medium-dimension) and then decreasing to 23.26% (thin-shell/small-cavity). Conversely, the FE for C 2 H 4 demonstrates an inverse structural correlation, improving from 6.68% (medium-dimension) to 38.73% (thin-shell/small-cavity). The spatial domain-limiting mechanism of the yolk-shell structure directly controls the transition between protonation-dominated CH 4 formation and coupling-driven C 2 H 4 production. This work establishes a pioneering paradigm for dynamically steering catalytic selectivity through purely geometrical modulation, bypassing traditional compositional tuning limitations, thereby opening avenues for precision design of advanced electrocatalytic systems.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Changsheng Feng,Yu Tian,Lifang Zheng,Yue Chen,Feiyue Ge,Fang Cheng,Xue-Jun Wu
Chiral plasmonic nanostructures provide an effective way to enhance circular dichroism (CD) activities of natural chiral molecules due to the strong coupling effect between molecular chirality and the surface plasmon. Nonetheless, the impact of the nanostructure parameters on the CD enhancement and the origin of the CD response is still not well-investigated. Here, we report a seed-mediated growth method to synthesize discrete Au@Ag core–shell decahedrons in the presence of cysteine by using concave 5-fold twinned Au nanocrystals as seeds. The produced core–shell decahedrons display a strong CD response in the plasmon resonance region, and the maximum Kuhn’s dissymmetry value (g factor) can reach to as high as 5.8 × 10–3 as well as a large CD enhancement factor over 2000. Comprehensive experiments reveal that embedded chiral cysteine in the outmost layer of the Ag shell plays the paramount role in inducing the CD activity, which ensures the good stability of the CD response of the nanostructures under long-term storage. Our finding inspires the rational design and synthesis of plasmonic CD systems with strong enhancement of the CD activities and expands their potential applications in chiral signal amplification and biosensing.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Sustainable Systems
·
2025
·
IF 6.1
Haiyu Ma,Jian Li,René Hübner,Xingyu Tao,Kairui Xu,Mingjia Lu,Jiakun Du,Muwu Li,Zhikun Zheng,Wei Liu
Platinum-based electrocatalysts represent the most promising candidates for the methanol oxidation reaction (MOR) in direct methanol fuel cells. However, the wide commercialization of platinum-based electrocatalysts faces significant challenges, including high material costs, insufficient catalytic activity, limited operational durability, and susceptibility to CO poisoning. To overcome these issues, a new Au-doped Pt-Co aerogel (AG) is fabricated by the facile one-pot aqueous-solution heteroatom doping method. This catalyst demonstrates good electrocatalytic performance for MOR, combining both high activity and remarkable stability. The Au 1 -Pt 67 Co 33 AG with optimized Au doping amount exhibits outstanding mass activity, which is 1.7 times that of its undoped Pt 67 Co 33 AG counterpart and 4.6 times that of the commercial Pt/C catalyst. Furthermore, the Au 1 -Pt 67 Co 33 AG demonstrates significantly enhanced long-term stability under continuous operation. Density functional theory calculations indicate that Au doping reduces the energy barriers for methanol dehydrogenation and lowers the total energy barriers for the *CO oxidation steps, facilitating the rapid dehydrogenation of CH n OH and faster conversion of *CO, thereby significantly enhancing the electrocatalytic activity and stability of the Au 1 -Pt 67 Co 33 AG toward MOR.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）